Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals

Cell Growth and Differentiation

Volumn 9, Issue 6, 1998, Pages 465-474

  Vaziri, Cyrus ^a   Stice, Ligaya ^a   Faller, Douglas V ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; PROTEIN P21; BUTYRIC ACID DERIVATIVE; CDKN1A PROTEIN, MOUSE; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; ONCOPROTEIN; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL SYNCHRONIZATION; CELL TRANSFORMATION; CELL TYPE; DNA SYNTHESIS INHIBITION; FIBROBLAST; GENE DISRUPTION; GROWTH INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; ANIMAL; CELL STRAIN 3T3; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION; GENETIC TRANSFECTION; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY;

3T3 CELLS; ANIMALS; BUTYRIC ACID; BUTYRIC ACIDS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DOSE-RESPONSE RELATIONSHIP, DRUG; G1 PHASE; GENE EXPRESSION; MICE; MICE, KNOCKOUT; ONCOGENE PROTEINS, VIRAL; PHOSPHORYLATION; RETINOBLASTOMA PROTEIN; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031596491     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Cummings, J. H., Pomare, E. W., Branch, W. J., Naylor, C. P. E., and MacFarlane, G. T. Short chain fatty acids in human large intestine, portal, hepatic, and venous blood. Gut, 28: 1221-1227, 1987.
2. D'Anna, J. A., Tobey, R. A., and Gurley, L. R. Concentration-dependent effects of sodium butyrate in Chinese hamster cells: cell cycle progression, inner histone acetylation, histone H1 dephosphorylation, and induction of an H1-like protein. Biochemistry, 19: 2656-2971, 1980.
3. Daniell, E. Cells inhibited by butyrate support adenovirus replication. Virology, 107: 514-519, 1980.
4. 1 phase. J. Cell. Biochem., 27: 239-247, 1983.
5. Staiano-Coico, L., Steinberg, M., and Higgins, P. J. Epidermal cell shape regulation and subpopulation kinetics during butyrate-induced terminal maturation of normal and SV40-transformed keratinocytes: epithelial models of differentiation therapy. Int. J. Cancer, 46: 733-738, 1990.
6. Balk, S., Gunther, H., and Morisi, A. Butyrate reversibly arrests the proliferation of normal and Rous sarcoma virus-infected chicken heart mesenchymal cells. Life Sci., 803-808, 1984.
7. Campisi, J., Medrano, E. E., Morreo, G., and Pardee, A. Restriction point control of cell growth by a labile protein: evidence for increased stability in transformed cells. Proc. Natl. Acad. Sci. USA, 79: 436-440, 1982.
8. Medrano, E. E., and Pardee, A. B. Prevalent deficiency in tumor cells of cycloheximide-induced cycle arrest. Proc. Natl. Acad. Sci. USA, 77: 4123-4126, 1980.
9. Boffa, L. C., Lupto, J. R., Mariani, M. R., Ceppi, M., Newmark, H. L., Scamati, A., and Lipkin, M. Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats. Cancer Res., 52: 5906-5912, 1992.
10. Hague, A., Manning, A. M., Hanlon, K. A., Huschtscha, L. I., Hart, D., and Paraskeva, C. Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large bowel cancer. Int J. Cancer, 55: 498-505, 1993.
11. 1, events and regulation of cell proliferation. Science (Washington DC), 240: 603-608, 1989.
12. Cantley, L. C., Auger, K. R., Carpenter, C., Duckworth, B., Graziani, A., Kapeller, R., and Soltoff, S. Oncogenes and signal transduction. Cell, 64: 281-302, 1991.
13. 1 cyclins. Cell, 73: 1059-1065, 1993.
14. Siavoshian, S., Blottiere, H. M., Cherbut, C., and Galmiche, J. P. Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells. Biochem. Biophys. Res. Commun., 232: 169-172, 1997.
15. Lallemand, F., Courilleau, D., Sabbah, M., Redeuilh, G., and Mester, J. Direct inhibition of the expression of cyclin D1 gene by sodium butyrate. Biochem. Biophys. Res. Commun., 229: 163-169, 1996.
16. Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
17. Herwig, S., and Strauss, M. The Rb protein: a master regulator of cell cycle, differentiation and apoptosis. Eur. J. Biochem., 246: 581-601, 1997.
18. Johnson, D. G., Schwarz, J. K., Cress, W. D. and Nevins, J. R. Expression of transcription factor E2F1 induces quiescent cells to enter S-phase. Nature (Lond.), 365: 349-352, 1993.
19. 1 cyclin-dependent kinases. Genes Dev., 9: 1149-1163, 1995.
20. Ko, L. J., and Prives, C. p53: puzzle and paradigm. Genes Dev., 10: 1054-1073, 1996.
21. Steinman, R. A., Hoffman, B., Iro, A., Guillouf, C., Lieberman, D. A., and el-Houseini, M. E. Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene, 9: 3389-3396, 1996.
22. Datto, M. B., Yu, Y., and Wang, X. F. Functional analysis of the transforming growth factor β responsive elements in the WAF1/Cip1/p21 promoter. J. Biol. Chem., 270: 28623-28628, 1995.
23. Nakano, K., Mizuno, T., Sowa, Y., Orita, T., Yoshino, T., Okuyama, Y., Fujita, T., Ohtani-Fujita, N., Matsukawa, Y., Tokino, T., Yamagishi, H., Oka, T., Nomura, H., and Sakai, T. Butyrate activates the WAF-1/CIP1 gene promoter through sp1 sites in a p53-negative colon cancer cell line. J. Biol. Chem., 272: 22199-22206, 1997.
24. Botz, J., Zerfass-Thome, K., Spitkovsky, D., Delius, H., Vogt, B., Eilers, M., Hatzigeorgiou, A., and Jansen-Durr, P. Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter. Mol. Cell. Biol., 16: 3401-3409, 1996.
25. Munger, K., Werness, B. A., Dyson, N., Phelps, W. C., Harlow, E., and Howley, P. M. Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J., 8: 4099-4105, 1989.
26. Nevins, J. R. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science (Washington DC), 258: 424-429, 1992.
27. Werness, B. A., Levine, A. J., and Howley, P. M. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (Washington DC), 248: 76-79, 1990.
28. Albanese, C., Johnson, J., Watanabe, G., Eklund, N., Vu, D., Arnold, A., and Pestell, R. G. Transforming p21 ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J. Biol. Chem., 270: 23589-23597, 1995.
29. Gorman, C. M., Howard, B. H., and Reeves, R. Expression of recombinant plasmids in mammalian cells is enhanced by sodium butyrate. Nucleic Acids Res., 11: 7631-7648, 1983.
30. Klehr, D., Schlake, T., Maass, K., and Bode, J. Scaffold-attached regions (SAR elements) mediate transcriptional effects due to butyrate. Biochemistry, 37: 3222-3229, 1992.
31. Candido, E. P. M., Reeves, R., and Davie, J. R. Sodium butyrate inhibits histone deacetylation in cultured cells. Cell, 14: 105-113, 1978.
32. Turner, B. M. Histone acetylation and control of gene expression. J. Cell Sci., 99: 13-20, 1991.
33. Wolffe, A. P., and Pruss, D. Targeting chromatin disruption: transcription regulators that acetylate histones. Cell, 84: 817-819, 1996.
34. Grunstein, M. Histone acetylation in chromatin structure and transcription. Nature (Lond.), 389: 349-352, 1997.
35. 2 phases by trichostatin A. Exp. Cell Res., 177: 122-131, 1988.
36. Faller, D. V., and Perrine, S. P. Butyrate in the treatment of sickle cell disease and β-thalassemia. Curr. Opin. Hematol., 2: 109-117, 1995.
37. Boosalis, M. S., Ikuta, T., Pace, B. S., daFonseca, S., White, G. L., Faller, D. V., and Perrine, S. P. Abrogation of II-3 requirements and stimulation of hematopoetic cell proliferation in vitro and in vivo by carboxylic acids. Blood Cells Mol. Dis., 23: 434-442, 1997.
38. Torkelson, S., White, B., Faller, D. V., Phipps, K., Pantazis, C., and Perrine, S. P. Erythroid progenitor proliferation is stimulated by phenoxyacetic and phenylalkyl acids. Blood Cells Mol. Dis., 22: 150-158, 1996.
39. 1 arrest in 3T3 fibroblasts. J. Biol. Chem., 272: 2762-2769, 1997.
40. Chomczynski, P., and Sacchi, N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.