Bitter Melon (Momordica charantia) extract inhibits breast cancer cell proliferation by modulating cell cycle regulatory genes and promotes apoptosis

Cancer Research

Volumn 70, Issue 5, 2010, Pages 1925-1931

  Ray, Ratna B ^a   Raychoudhuri, Amit ^a   Steele, Robert ^a   Nerurkar, Pratibha ^b  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF HAWAII   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CLASPIN; CYCLIN B1; CYCLIN D1; MOMORDICA CHARANTIA EXTRACT; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN P21; PROTEIN P53; SURVIVIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL STRAIN MDA MB 231; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; FLUORESCENCE ACTIVATED CELL SORTING; GENE CONTROL; GENE FUNCTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOMORDICA CHARANTIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; BREAST NEOPLASMS; CASPASES; CELL CYCLE PROTEINS; CELL DIVISION; CELL GROWTH PROCESSES; CELL LINE, TUMOR; ENZYME ACTIVATION; FEMALE; G2 PHASE; GENES, CDC; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MOMORDICA CHARANTIA; PLANT EXTRACTS;

EID: 77950278220     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-3438     Document Type: Article

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