-
1
-
-
78650575238
-
Vaccines to combat the neglected tropical diseases
-
J.M. Bethony, R.N. Cole, X. Guo, S. Kamhawi, M.W. Lightowlers, and A. Loukas Vaccines to combat the neglected tropical diseases Immunol Rev 239 2011 237 270
-
(2011)
Immunol Rev
, vol.239
, pp. 237-270
-
-
Bethony, J.M.1
Cole, R.N.2
Guo, X.3
Kamhawi, S.4
Lightowlers, M.W.5
Loukas, A.6
-
2
-
-
77958082295
-
Developing vaccines to combat hookworm infection and intestinal schistosomiasis
-
P.J. Hotez, J.M. Bethony, D.J. Diemert, M. Pearson, and A. Loukas Developing vaccines to combat hookworm infection and intestinal schistosomiasis Nat Rev Microbiol 8 2010 814 826
-
(2010)
Nat Rev Microbiol
, vol.8
, pp. 814-826
-
-
Hotez, P.J.1
Bethony, J.M.2
Diemert, D.J.3
Pearson, M.4
Loukas, A.5
-
3
-
-
49449092450
-
Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis
-
P.J. Hotez, J.M. Bethony, S.C. Oliveira, P.J. Brindley, and A. Loukas Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis Expert Rev Vaccines 7 2008 745 752
-
(2008)
Expert Rev Vaccines
, vol.7
, pp. 745-752
-
-
Hotez, P.J.1
Bethony, J.M.2
Oliveira, S.C.3
Brindley, P.J.4
Loukas, A.5
-
4
-
-
56149124411
-
Hookworm-related anaemia among pregnant women: A systematic review
-
S. Brooker, P.J. Hotez, and D.A. Bundy Hookworm-related anaemia among pregnant women: a systematic review PLoS Negl Trop Dis 2 2008 e291
-
(2008)
PLoS Negl Trop Dis
, vol.2
, pp. 291
-
-
Brooker, S.1
Hotez, P.J.2
Bundy, D.A.3
-
5
-
-
77953193904
-
Impact of hookworm infection and deworming on anaemia in non-pregnant populations: A systematic review
-
J.L. Smith, and S. Brooker Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review Trop Med Int Health 15 2010 776 795
-
(2010)
Trop Med Int Health
, vol.15
, pp. 776-795
-
-
Smith, J.L.1
Brooker, S.2
-
6
-
-
0028851648
-
Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area
-
M. Albonico, P.G. Smith, E. Ercole, A. Hall, H.M. Chwaya, and K.S. Alawi Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area Trans R Soc Trop Med Hyg 89 1995 538 541
-
(1995)
Trans R Soc Trop Med Hyg
, vol.89
, pp. 538-541
-
-
Albonico, M.1
Smith, P.G.2
Ercole, E.3
Hall, A.4
Chwaya, H.M.5
Alawi, K.S.6
-
7
-
-
6044246292
-
Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: A pressing public health agenda for helminth control
-
DOI 10.1016/j.ijpara.2004.08.001, PII S0020751904001651
-
M. Albonico, D. Engels, and L. Savioli Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control Int J Parasitol 34 2004 1205 1210 (Pubitemid 39382392)
-
(2004)
International Journal for Parasitology
, vol.34
, Issue.11
, pp. 1205-1210
-
-
Albonico, M.1
Engels, D.2
Savioli, L.3
-
8
-
-
0017752540
-
Skin penetration of infective hookworm larvae. II. The path of migration of infective larvae of Ancylostoma braziliense in the metacarpal foot pads of dogs
-
J.C. Vetter, and M.E. van der Linden Skin penetration of infective hookworm larvae. II. The path of migration of infective larvae of Ancylostoma braziliense in the metacarpal foot pads of dogs Z Parasitenkd 53 1977 263 266 (Pubitemid 8212770)
-
(1977)
Zeitschrift fur Parasitenkunde
, vol.53
, Issue.3
, pp. 263-266
-
-
Vetter, J.C.M.1
Leegwater, V.D.2
Linden, M.E.3
-
9
-
-
0017771950
-
Skin penetration of infective hookworm larvae. I. The path of migration of infective larvae of Ancylostoma braziliense in canine skin
-
J.C. Vetter, and M.E. van der Linden Skin penetration of infective hookworm larvae. I. The path of migration of infective larvae of Ancylostoma braziliense in canine skin Z Parasitenkd 53 1977 255 262 (Pubitemid 8212769)
-
(1977)
Zeitschrift fur Parasitenkunde
, vol.53
, Issue.3
, pp. 255-262
-
-
Vetter, J.C.M.1
Leegwater, V.D.2
Linden, M.E.3
-
10
-
-
4143058228
-
Hookworm infection
-
P.J. Hotez, S. Brooker, J.M. Bethony, M.E. Bottazzi, A. Loukas, and S. Xiao Hookworm infection N Engl J Med 351 2004 799 807
-
(2004)
N Engl J Med
, vol.351
, pp. 799-807
-
-
Hotez, P.J.1
Brooker, S.2
Bethony, J.M.3
Bottazzi, M.E.4
Loukas, A.5
Xiao, S.6
-
11
-
-
10444241029
-
Human hookworm infection in the 21st century
-
DOI 10.1016/S0065-308X(04)58004-1, PII S0065308X04580041
-
S. Brooker, J. Bethony, and P.J. Hotez Human hookworm infection in the 21st century Adv Parasitol 58 2004 197 288 (Pubitemid 39643145)
-
(2004)
Advances in Parasitology
, vol.58
, pp. 197-288
-
-
Brooker, S.1
Bethony, J.2
Hotez, P.J.3
-
12
-
-
79956215244
-
Twenty-first century progress toward the global control of human hookworm infection
-
R. Bungiro, and M. Cappello Twenty-first century progress toward the global control of human hookworm infection Curr Infect Dis Rep 13 2011 210 217
-
(2011)
Curr Infect Dis Rep
, vol.13
, pp. 210-217
-
-
Bungiro, R.1
Cappello, M.2
-
13
-
-
0032900715
-
Necator americanus (human hookworm) aspartyl proteinases and digestion of skin macromolecules during skin penetration
-
A. Brown, N. Girod, E.E. Billett, and D.I. Pritchard Necator americanus (human hookworm) aspartyl proteinases and digestion of skin macromolecules during skin penetration Am J Trop Med Hyg 60 1999 840 847 (Pubitemid 29233091)
-
(1999)
American Journal of Tropical Medicine and Hygiene
, vol.60
, Issue.5
, pp. 840-847
-
-
Brown, A.1
Girod, N.2
Billett, E.E.3
Pritchard, D.I.4
-
14
-
-
0345118193
-
Hookworm cathepsin D aspartic proteases: Contributing roles in the host-specific degradation of serum proteins and skin macromolecules
-
DOI 10.1017/S0031182002002706
-
A.L. Williamson, P.J. Brindley, and A. Loukas Hookworm cathepsin D aspartic proteases: contributing roles in the host-specific degradation of serum proteins and skin macromolecules Parasitology 126 2003 179 185 (Pubitemid 36308254)
-
(2003)
Parasitology
, vol.126
, Issue.2
, pp. 179-185
-
-
Williamson, A.L.1
Brindley, P.J.2
Loukas, A.3
-
15
-
-
11844256383
-
Mechanism and biological significance of CD44 cleavage
-
DOI 10.1111/j.1349-7006.2004.tb03179.x
-
O. Nagano, and H. Saya Mechanism and biological significance of CD44 cleavage Cancer Sci 95 2004 930 935 (Pubitemid 40089583)
-
(2004)
Cancer Science
, vol.95
, Issue.12
, pp. 930-935
-
-
Nagano, O.1
Saya, H.2
-
16
-
-
0026511191
-
Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans
-
P.J. Hotez, S. Narasimhan, J. Haggerty, L. Milstone, V. Bhopale, and G.A. Schad Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans Infect Immun 60 1992 1018 1023
-
(1992)
Infect Immun
, vol.60
, pp. 1018-1023
-
-
Hotez, P.J.1
Narasimhan, S.2
Haggerty, J.3
Milstone, L.4
Bhopale, V.5
Schad, G.A.6
-
17
-
-
0025607058
-
Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis
-
P. Hotez, J. Haggerty, J. Hawdon, L. Milstone, H.R. Gamble, and G. Schad Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis Infect Immun 58 1990 3883 3892
-
(1990)
Infect Immun
, vol.58
, pp. 3883-3892
-
-
Hotez, P.1
Haggerty, J.2
Hawdon, J.3
Milstone, L.4
Gamble, H.R.5
Schad, G.6
-
18
-
-
31844452690
-
Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration
-
DOI 10.1128/IAI.74.2.961-967.2006
-
A.L. Williamson, S. Lustigman, Y. Oksov, V. Deumic, J. Plieskatt, and S. Mendez Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration Infection and immunity 74 2006 961 967 (Pubitemid 43185531)
-
(2006)
Infection and Immunity
, vol.74
, Issue.2
, pp. 961-967
-
-
Williamson, A.L.1
Lustigman, S.2
Oksov, Y.3
Deumic, V.4
Plieskatt, J.5
Mendez, S.6
Zhan, B.7
Bottazzi, M.E.8
Hotez, P.J.9
Loukas, A.10
-
19
-
-
0033179482
-
The families of pathogenesis-related proteins, their activities, and comparative analysis of PR-1 type proteins
-
DOI 10.1006/pmpp.1999.0213
-
L.C. Van Loon, and E.A. Van Strien The families of pathogenesis-related proteins, their activities, and comparative analysis of PR-1 type proteins Physiol Mol Plant Pathol 55 1999 85 97 (Pubitemid 29402750)
-
(1999)
Physiological and Molecular Plant Pathology
, vol.55
, Issue.2
, pp. 85-97
-
-
Van Loon, L.C.1
Van Strien, E.A.2
-
20
-
-
23844481209
-
Characterization of the SCP/TAPS gene family in Drosophila melanogaster
-
DOI 10.1016/j.ibmb.2005.03.003
-
G.E. Kovalick, and D.L. Griffin Characterization of the SCP/TAPS gene family in Drosophila melanogaster Insect Biochem Mol Biol 35 2005 825 835 (Pubitemid 41556946)
-
(2005)
Insect Biochemistry and Molecular Biology
, vol.35
, Issue.8
, pp. 825-835
-
-
Kovalick, G.E.1
Griffin, D.L.2
-
21
-
-
0037376935
-
Wide distribution of cysteine-rich secretory proteins in snake venoms: Isolation and cloning of novel snake venom cysteine-rich secretory proteins
-
DOI 10.1016/S0003-9861(03)00028-6
-
Y. Yamazaki, F. Hyodo, and T. Morita Wide distribution of cysteine-rich secretory proteins in snake venoms: isolation and cloning of novel snake venom cysteine-rich secretory proteins Arch Biochem Biophys 412 2003 133 141 (Pubitemid 36324373)
-
(2003)
Archives of Biochemistry and Biophysics
, vol.412
, Issue.1
, pp. 133-141
-
-
Yamazaki, Y.1
Hyodo, F.2
Morita, T.3
-
22
-
-
0029989299
-
Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae
-
J.M. Hawdon, B.F. Jones, D.R. Hoffman, and P.J. Hotez Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae J Biol Chem 271 1996 6672 6678
-
(1996)
J Biol Chem
, vol.271
, pp. 6672-6678
-
-
Hawdon, J.M.1
Jones, B.F.2
Hoffman, D.R.3
Hotez, P.J.4
-
23
-
-
0032934497
-
Ancylostoma secreted protein 2: Cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum
-
DOI 10.1016/S0166-6851(99)00011-0, PII S0166685199000110
-
J.M. Hawdon, S. Narasimhan, and P.J. Hotez Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum Mol Biochem Parasitol 99 1999 149 165 (Pubitemid 29182679)
-
(1999)
Molecular and Biochemical Parasitology
, vol.99
, Issue.2
, pp. 149-165
-
-
Hawdon, J.M.1
Narasimhan, S.2
Hotez, P.J.3
-
24
-
-
48949107733
-
Transcriptional changes in the hookworm, Ancylostoma caninum, during the transition from a free-living to a parasitic larva
-
B.J. Datu, R.B. Gasser, S.H. Nagaraj, E.K. Ong, P. O'Donoghue, and R. McInnes Transcriptional changes in the hookworm, Ancylostoma caninum, during the transition from a free-living to a parasitic larva PLoS Negl Trop Dis 2 2008 e130
-
(2008)
PLoS Negl Trop Dis
, vol.2
, pp. 130
-
-
Datu, B.J.1
Gasser, R.B.2
Nagaraj, S.H.3
Ong, E.K.4
O'Donoghue, P.5
McInnes, R.6
-
25
-
-
70350359468
-
Male-enriched transcription of genes encoding ASPs and Kunitz-type protease inhibitors in Ancylostoma species
-
A.F. Costa, R.B. Gasser, S.R. Dias, and E.M. Rabelo Male-enriched transcription of genes encoding ASPs and Kunitz-type protease inhibitors in Ancylostoma species Mol Cell Probes 23 2009 298 303
-
(2009)
Mol Cell Probes
, vol.23
, pp. 298-303
-
-
Costa, A.F.1
Gasser, R.B.2
Dias, S.R.3
Rabelo, E.M.4
-
26
-
-
77955293684
-
Massively parallel sequencing and analysis of the Necator americanus transcriptome
-
C. Cantacessi, M. Mitreva, A.R. Jex, N.D. Young, B.E. Campbell, and R.S. Hall Massively parallel sequencing and analysis of the Necator americanus transcriptome PLoS Negl Trop Dis 4 2010 e684
-
(2010)
PLoS Negl Trop Dis
, vol.4
, pp. 684
-
-
Cantacessi, C.1
Mitreva, M.2
Jex, A.R.3
Young, N.D.4
Campbell, B.E.5
Hall, R.S.6
-
27
-
-
0142124395
-
Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum
-
DOI 10.1016/S0020-7519(03)00111-5
-
B. Zhan, Y. Liu, M. Badamchian, A. Williamson, J. Feng, and A. Loukas Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum Int J Parasitol 33 2003 897 907 (Pubitemid 37297457)
-
(2003)
International Journal for Parasitology
, vol.33
, Issue.9
, pp. 897-907
-
-
Zhan, B.1
Liu, Y.2
Badamchian, M.3
Williamson, A.4
Feng, J.5
Loukas, A.6
Hawdon, J.M.7
Hotez, P.J.8
-
28
-
-
59149091643
-
Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum
-
J. Mulvenna, B. Hamilton, S.H. Nagaraj, D. Smyth, A. Loukas, and J.J. Gorman Proteomics analysis of the excretory/secretory component of the blood-feeding stage of the hookworm, Ancylostoma caninum Mol Cell Proteomics 8 2009 109 121
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 109-121
-
-
Mulvenna, J.1
Hamilton, B.2
Nagaraj, S.H.3
Smyth, D.4
Loukas, A.5
Gorman, J.J.6
-
29
-
-
13844275516
-
X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection
-
DOI 10.1016/j.jmb.2004.12.023
-
O.A. Asojo, G. Goud, K. Dhar, A. Loukas, B. Zhan, and V. Deumic X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection J Mol Biol 346 2005 801 814 (Pubitemid 40247719)
-
(2005)
Journal of Molecular Biology
, vol.346
, Issue.3
, pp. 801-814
-
-
Asojo, O.A.1
Goud, G.2
Dhar, K.3
Loukas, A.4
Zhan, B.5
Deumic, V.6
Liu, S.7
Borgstahl, G.E.O.8
Hotez, P.J.9
-
30
-
-
40649090624
-
Necator americanus: The Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro
-
M.A. Bower, S.L. Constant, and S. Mendez Necator americanus: the Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro Exp Parasitol 118 2008 569 575
-
(2008)
Exp Parasitol
, vol.118
, pp. 569-575
-
-
Bower, M.A.1
Constant, S.L.2
Mendez, S.3
-
31
-
-
0028305898
-
A hookworm glycoprotein that inhibits neutrophil function is a ligand of the integrin CD11b/CD18
-
M. Moyle, D.L. Foster, D.E. McGrath, S.M. Brown, Y. Laroche, and J. De Meutter A hookworm glycoprotein that inhibits neutrophil function is a ligand of the integrin CD11b/CD18 J Biol Chem 269 1994 10008 10015 (Pubitemid 24196615)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.13
, pp. 10008-10015
-
-
Moyle, M.1
Foster, D.L.2
McGrath, D.E.3
Brown, S.M.4
Laroche, Y.5
De Meutter, J.6
Stanssens, P.7
Bogowitz, C.A.8
Fried, V.A.9
Ely, J.A.10
Soule, H.R.11
Vlasuk, G.P.12
-
32
-
-
0028020563
-
Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18
-
P.J. Muchowski, L. Zhang, E.R. Chang, H.R. Soule, E.F. Plow, and M. Moyle Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18 J Biol Chem 269 1994 26419 26423 (Pubitemid 24328464)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.42
, pp. 26419-26423
-
-
Muchowski, P.J.1
Zhang, L.2
Chang, E.R.3
Soule, H.R.4
Plow, E.F.5
Moyle, M.6
-
33
-
-
0028557171
-
The A-domain of beta 2 integrin CR3 (CD11b/CD18) is a receptor for the hookworm-derived neutrophil adhesion inhibitor NIF
-
P. Rieu, T. Ueda, I. Haruta, C.P. Sharma, and M.A. Arnaout The A-domain of beta 2 integrin CR3 (CD11b/CD18) is a receptor for the hookworm-derived neutrophil adhesion inhibitor NIF J Cell Biol 127 1994 2081 2091
-
(1994)
J Cell Biol
, vol.127
, pp. 2081-2091
-
-
Rieu, P.1
Ueda, T.2
Haruta, I.3
Sharma, C.P.4
Arnaout, M.A.5
-
34
-
-
0033991240
-
Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus
-
L. Sen, K. Ghosh, Z. Bin, S. Qiang, M.G. Thompson, and J.M. Hawdon Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus Vaccine 18 2000 1096 1102
-
(2000)
Vaccine
, vol.18
, pp. 1096-1102
-
-
Sen, L.1
Ghosh, K.2
Bin, Z.3
Qiang, S.4
Thompson, M.G.5
Hawdon, J.M.6
-
35
-
-
26444585581
-
Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals
-
DOI 10.1096/fj.05-3936fje
-
J. Bethony, A. Loukas, M. Smout, S. Brooker, S. Mendez, and J. Plieskatt Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals FASEB J 19 2005 1743 1745 (Pubitemid 41429549)
-
(2005)
FASEB Journal
, vol.19
, Issue.12
, pp. 1743-1745
-
-
Bethony, J.1
Loukas, A.2
Smout, M.3
Brooker, S.4
Mendez, S.5
Plieskatt, J.6
Goud, G.7
Bottazzi, M.E.8
Zhan, B.9
Wang, Y.10
Williamson, A.11
Lustigman, S.12
Correa-Oliveira, R.13
Xiao, S.14
Hotez, P.J.15
-
36
-
-
25144446399
-
Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials
-
DOI 10.1016/j.vaccine.2005.04.040
-
G.N. Goud, M.E. Bottazzi, B. Zhan, S. Mendez, V. Deumic, and J. Plieskatt Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials Vaccine 23 2005 4754 4764 (Pubitemid 41557326)
-
(2005)
Vaccine
, vol.23
, Issue.39
, pp. 4754-4764
-
-
Goud, G.N.1
Bottazzi, M.E.2
Zhan, B.3
Mendez, S.4
Deumic, V.5
Plieskatt, J.6
Liu, S.7
Wang, Y.8
Bueno, L.9
Fujiwara, R.10
Samuel, A.11
Ahn, S.Y.12
Solanki, M.13
Asojo, O.A.14
Wang, J.15
Bethony, J.M.16
Loukas, A.17
Roy, M.18
Hotez, P.J.19
-
37
-
-
42649132461
-
Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults
-
J.M. Bethony, G. Simon, D.J. Diemert, D. Parenti, A. Desrosiers, and S. Schuck Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults Vaccine 26 2008 2408 2417
-
(2008)
Vaccine
, vol.26
, pp. 2408-2417
-
-
Bethony, J.M.1
Simon, G.2
Diemert, D.J.3
Parenti, D.4
Desrosiers, A.5
Schuck, S.6
-
38
-
-
70149124302
-
Survival of the fittest: Allergology or parasitology?
-
C.M. Fitzsimmons, and D.W. Dunne Survival of the fittest: allergology or parasitology? Trends Parasitol 25 2009 447 451
-
(2009)
Trends Parasitol
, vol.25
, pp. 447-451
-
-
Fitzsimmons, C.M.1
Dunne, D.W.2
-
39
-
-
0020608172
-
Secretion of a proteolytic anticoagulant by Ancylostoma hookworms
-
P.J. Hotez, and A. Cerami Secretion of a proteolytic anticoagulant by Ancylostoma hookworms J Exp Med 157 1983 1594 1603 (Pubitemid 13088999)
-
(1983)
Journal of Experimental Medicine
, vol.157
, Issue.5
, pp. 1594-1603
-
-
Hotez, P.J.1
Cerami, A.2
-
40
-
-
0016339003
-
Intestinal trauma resulting from feeding activities of Ancylostoma caninum
-
U.P. Kalkofen Intestinal trauma resulting from feeding activities of Ancylostoma caninum Am J Trop Med Hyg 23 1974 1046 1053
-
(1974)
Am J Trop Med Hyg
, vol.23
, pp. 1046-1053
-
-
Kalkofen, U.P.1
-
41
-
-
33847258857
-
Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum
-
J. Feng, B. Zhan, Y. Liu, S. Liu, A. Williamson, and G. Goud Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum Mol Biochem Parasitol 152 2007 132 138
-
(2007)
Mol Biochem Parasitol
, vol.152
, pp. 132-138
-
-
Feng, J.1
Zhan, B.2
Liu, Y.3
Liu, S.4
Williamson, A.5
Goud, G.6
-
42
-
-
0000033507
-
The influence of extracts of Ancylostoma caninum on the coagulation of the blood and haemolysis
-
L. Loeb The influence of extracts of Ancylostoma caninum on the coagulation of the blood and haemolysis J Infect Dis 7 1910 625 631
-
(1910)
J Infect Dis
, vol.7
, pp. 625-631
-
-
Loeb, L.1
-
43
-
-
0027155257
-
Ancylostoma factor Xa inhibitor: Partial purification and its identification as a major hookworm-derived anticoagulant in vitro
-
M. Cappello, L.P. Clyne, P. McPhedran, and P.J. Hotez Ancylostoma factor Xa inhibitor: partial purification and its identification as a major hookworm-derived anticoagulant in vitro J Infect Dis 167 1993 1474 1477 (Pubitemid 23146209)
-
(1993)
Journal of Infectious Diseases
, vol.167
, Issue.6
, pp. 1474-1477
-
-
Cappello, M.1
Clyne, L.P.2
McPhedran, P.3
Hotez, P.J.4
-
44
-
-
0030249127
-
Ancylostoma caninum anticoagulant peptide: Cloning by PCR and expression of soluble, active protein in E. coli
-
DOI 10.1016/0166-6851(96)02658-8
-
M. Cappello, J.M. Hawdon, B.F. Jones, W.P. Kennedy, and P.J. Hotez Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli Mol Biochem Parasitol 80 1996 113 117 (Pubitemid 26284391)
-
(1996)
Molecular and Biochemical Parasitology
, vol.80
, Issue.1
, pp. 113-117
-
-
Cappello, M.1
Hawdon, J.M.2
Jones, B.F.3
Kennedy, W.P.4
Hotez, P.J.5
-
45
-
-
0029014045
-
Ancylostoma caninum anticoagulant peptide: A hookworm-derived inhibitor of human coagulation factor Xa
-
M. Cappello, G.P. Vlasuk, P.W. Bergum, S. Huang, and P.J. Hotez Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa Proc Natl Acad Sci U S A 92 1995 6152 6156
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 6152-6156
-
-
Cappello, M.1
Vlasuk, G.P.2
Bergum, P.W.3
Huang, S.4
Hotez, P.J.5
-
46
-
-
0035007328
-
Ancylostoma caninum anticoagulant peptide-5: Immunolocalization and in vitro neutralization of a major hookworm anti-thrombotic
-
DOI 10.1016/S0166-6851(01)00276-6, PII S0166685101002766
-
L.M. Harrison, J.L. Cordova, and M. Cappello Ancylostoma caninum anticoagulant peptide-5: immunolocalization and in vitro neutralization of a major hookworm anti-thrombotic Mol Biochem Parasitol 115 2001 101 107 (Pubitemid 32493857)
-
(2001)
Molecular and Biochemical Parasitology
, vol.115
, Issue.1
, pp. 101-107
-
-
Harrison, L.M.1
Cordova, J.L.2
Cappello, M.3
-
47
-
-
79952446683
-
Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum
-
D. Jiang, B. Zhan, R.S. Mayor, P. Gillespie, B. Keegan, and M.E. Bottazzi Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum Mol Biochem Parasitol 177 2011 42 48
-
(2011)
Mol Biochem Parasitol
, vol.177
, pp. 42-48
-
-
Jiang, D.1
Zhan, B.2
Mayor, R.S.3
Gillespie, P.4
Keegan, B.5
Bottazzi, M.E.6
-
48
-
-
75749103376
-
Identification of an anticoagulant peptide that inhibits both fXIa and fVIIa/tissue factor from the blood-feeding nematode Ancylostoma caninum
-
D. Li, Q. He, T. Kang, H. Yin, X. Jin, and H. Li Identification of an anticoagulant peptide that inhibits both fXIa and fVIIa/tissue factor from the blood-feeding nematode Ancylostoma caninum Biochem Biophys Res Commun 392 2010 155 159
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 155-159
-
-
Li, D.1
He, Q.2
Kang, T.3
Yin, H.4
Jin, X.5
Li, H.6
-
49
-
-
0000455702
-
Anticoagulant repertoire of the hookworm Ancylostoma caninum
-
DOI 10.1073/pnas.93.5.2149
-
P. Stassens, P.W. Bergum, Y. Gansemans, L. Jespers, Y. Laroche, and S. Huang Anticoagulant repertoire of the hookworm Ancylostoma caninum Proc Natl Acad Sci U S A 93 1996 2149 2154 (Pubitemid 26079896)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.5
, pp. 2149-2154
-
-
Stanssens, P.1
Bergum, P.W.2
Gansemans, Y.3
Jespers, L.4
Laroche, Y.5
Huang, S.6
Maki, S.7
Messens, J.8
Lauwereys, M.9
Cappello, M.10
Hotez, P.J.11
Lasters, I.12
Vlasuk, G.P.13
-
50
-
-
3342988385
-
Ancylostoma ceylanicum anticoagulant peptide-1: Role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa
-
DOI 10.1016/j.molbiopara.2004.05.011, PII S0166685104001550
-
J. Mieszczanek, L.M. Harrison, and M. Cappello Ancylostoma ceylanicum anticoagulant peptide-1: role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa Mol Biochem Parasitol 137 2004 151 159 (Pubitemid 38987952)
-
(2004)
Molecular and Biochemical Parasitology
, vol.137
, Issue.1
, pp. 151-159
-
-
Mieszczanek, J.1
Harrison, L.M.2
Cappello, M.3
-
51
-
-
67349125443
-
An anticoagulant peptide from the human hookworm, Ancylostoma duodenale that inhibits coagulation factors Xa and XIa
-
W. Gan, L. Deng, C. Yang, Q. He, J. Hu, and H. Yin An anticoagulant peptide from the human hookworm, Ancylostoma duodenale that inhibits coagulation factors Xa and XIa FEBS Lett 583 2009 1976 1980
-
(2009)
FEBS Lett
, vol.583
, pp. 1976-1980
-
-
Gan, W.1
Deng, L.2
Yang, C.3
He, Q.4
Hu, J.5
Yin, H.6
-
52
-
-
0348048783
-
Anticoagulant peptides from Ancylostoma caninum are immunologically distinct and localize to separate structures within the adult hookworm
-
DOI 10.1016/j.molbiopara.2003.10.015
-
J. Mieszczanek, L.M. Harrison, G.P. Vlasuk, and M. Cappello Anticoagulant peptides from Ancylostoma caninum are immunologically distinct and localize to separate structures within the adult hookworm Mol Biochem Parasitol 133 2004 319 323 (Pubitemid 38032880)
-
(2004)
Molecular and Biochemical Parasitology
, vol.133
, Issue.2
, pp. 319-323
-
-
Mieszczanek, J.1
Harrison, L.M.2
Vlasuk, G.P.3
Cappello, M.4
-
53
-
-
33646789135
-
A survey of the intestinal transcriptomes of the hookworms, Necator americanus and Ancylostoma caninum, using tissues isolated by laser microdissection microscopy
-
DOI 10.1016/j.ijpara.2006.01.015, PII S0020751906000385
-
N. Ranjit, M.K. Jones, D.J. Stenzel, R.B. Gasser, and A. Loukas A survey of the intestinal transcriptomes of the hookworms, Necator americanus and Ancylostoma caninum, using tissues isolated by laser microdissection microscopy Int J Parasitol 36 2006 701 710 (Pubitemid 43765726)
-
(2006)
International Journal for Parasitology
, vol.36
, Issue.6
, pp. 701-710
-
-
Ranjit, N.1
Jones, M.K.2
Stenzel, D.J.3
Gasser, R.B.4
Loukas, A.5
-
54
-
-
0033013065
-
1) inhibits platelet aggregation and adhesion in vitro
-
DOI 10.1086/314724
-
R.C. Chadderdon, and M. Cappello The hookworm platelet inhibitor: functional blockade of integrins GPIIb/IIIa (alphaIIbbeta3) and GPIa/IIa (alpha2beta1) inhibits platelet aggregation and adhesion in vitro J Infect Dis 179 1999 1235 1241 (Pubitemid 29196506)
-
(1999)
Journal of Infectious Diseases
, vol.179
, Issue.5
, pp. 1235-1241
-
-
Chadderdon, R.C.1
Cappello, M.2
-
55
-
-
0038015446
-
Isolation and molecular cloning of a secreted hookworm platelet inhibitor from adult Ancylostoma caninum
-
DOI 10.1016/S0166-6851(03)00121-X
-
A. Del Valle, B.F. Jones, L.M. Harrison, R.C. Chadderdon, and M. Cappello Isolation and molecular cloning of a secreted hookworm platelet inhibitor from adult Ancylostoma caninum Mol Biochem Parasitol 129 2003 167 177 (Pubitemid 36794569)
-
(2003)
Molecular and Biochemical Parasitology
, vol.129
, Issue.2
, pp. 167-177
-
-
Del Valle, A.1
Jones, B.F.2
Harrison, L.M.3
Chadderdon, R.C.4
Cappello, M.5
-
56
-
-
4143084912
-
A pore-forming haemolysin from the hookworm, Ancylostoma caninum
-
DOI 10.1016/j.ijpara.2004.04.013, PII S0020751904001122
-
T.A. Don, M.K. Jones, D. Smyth, P. O'Donoghue, P. Hotez, and A. Loukas A pore-forming haemolysin from the hookworm, Ancylostoma caninum Int J Parasitol 34 2004 1029 1035 (Pubitemid 39093802)
-
(2004)
International Journal for Parasitology
, vol.34
, Issue.9
, pp. 1029-1035
-
-
Don, T.A.1
Jones, M.K.2
Smyth, D.3
O'Donoghue, P.4
Hotez, P.5
Loukas, A.6
-
57
-
-
0032514902
-
Lysosomal degradation on vesicular membrane surfaces: Enhanced glucosylceramide degradation by lysosomal anionic lipids and activators
-
DOI 10.1074/jbc.273.46.30271
-
G. Wilkening, T. Linke, and K. Sandhoff Lysosomal degradation on vesicular membrane surfaces. Enhanced glucosylceramide degradation by lysosomal anionic lipids and activators J Biol Chem 273 1998 30271 30278 (Pubitemid 28545494)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.46
, pp. 30271-30278
-
-
Wilkening, G.1
Linke, T.2
Sandhoff, K.3
-
58
-
-
4344630150
-
A novel Fasciola hepatica saposinlike recombinant protein with immunoprophylactic potential
-
DOI 10.1645/GE-215R
-
A.M. Espino, and G.V. Hillyer A novel Fasciola hepatica saposinlike recombinant protein with immunoprophylactic potential J Parasitol 90 2004 876 879 (Pubitemid 39128753)
-
(2004)
Journal of Parasitology
, vol.90
, Issue.4
, pp. 876-879
-
-
Espino, A.M.1
Hillyer, G.V.2
-
59
-
-
0036387114
-
Hemolytic activity and developmental expression of pore-forming peptide, clonorin
-
J.Y. Lee, P.Y. Cho, T.Y. Kim, S.Y. Kang, K.Y. Song, and S.J. Hong Hemolytic activity and developmental expression of pore-forming peptide, clonorin Biochem Biophys Res Commun 296 2002 1238 1244
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 1238-1244
-
-
Lee, J.Y.1
Cho, P.Y.2
Kim, T.Y.3
Kang, S.Y.4
Song, K.Y.5
Hong, S.J.6
-
60
-
-
2342445863
-
Solution Structure of the Pore-forming Protein of Entamoeba histolytica
-
DOI 10.1074/jbc.M312978200
-
O. Hecht, N.A. Van Nuland, K. Schleinkofer, A.J. Dingley, H. Bruhn, and M. Leippe Solution structure of the pore-forming protein of Entamoeba histolytica J Biol Chem 279 2004 17834 17841 (Pubitemid 38560551)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.17
, pp. 17834-17841
-
-
Hecht, O.1
Van Nuland, N.A.2
Schleinkofer, K.3
Dingley, A.J.4
Bruhn, H.5
Leippe, M.6
Grotzinger, J.7
-
61
-
-
33846809115
-
Saposin-like proteins from the intestine of the blood-feeding hookworm, Ancylostoma caninum
-
DOI 10.1017/S003118200600148X, PII S003118200600148X
-
T.A. Don, Y. Oksov, S. Lustigman, and A. Loukas Saposin-like proteins from the intestine of the blood-feeding hookworm, Ancylostoma caninum Parasitology 134 2007 427 436 (Pubitemid 46208025)
-
(2007)
Parasitology
, vol.134
, Issue.3
, pp. 427-436
-
-
Don, T.A.1
Oksov, Y.2
Lustigman, S.3
Loukas, A.4
-
62
-
-
80053450286
-
Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm
-
C. Willis, C.K. Wang, A. Osman, A. Simon, D. Pickering, and J. Mulvenna Insights into the membrane interactions of the saposin-like proteins Na-SLP-1 and Ac-SLP-1 from human and dog hookworm PLoS One 6 2011 e25369
-
(2011)
PLoS One
, vol.6
, pp. 25369
-
-
Willis, C.1
Wang, C.K.2
Osman, A.3
Simon, A.4
Pickering, D.5
Mulvenna, J.6
-
63
-
-
65649122615
-
Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus
-
N. Ranjit, B. Zhan, B. Hamilton, D. Stenzel, J. Lowther, and M. Pearson Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus J Infect Dis 199 2009 904 912
-
(2009)
J Infect Dis
, vol.199
, pp. 904-912
-
-
Ranjit, N.1
Zhan, B.2
Hamilton, B.3
Stenzel, D.4
Lowther, J.5
Pearson, M.6
-
64
-
-
4143054944
-
A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms
-
DOI 10.1074/jbc.M405842200
-
A.L. Williamson, P. Lecchi, B.E. Turk, Y. Choe, P.J. Hotez, and J.H. McKerrow A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms J Biol Chem 279 2004 35950 35957 (Pubitemid 39100602)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.34
, pp. 35950-35957
-
-
Williamson, A.L.1
Lecchi, P.2
Turk, B.E.3
Choe, Y.4
Hotez, P.J.5
McKerrow, J.H.6
Cantley, L.C.7
Sajid, M.8
Craik, C.S.9
Loukas, A.10
-
65
-
-
1942519435
-
Blood 'n' guts: An update on schistosome digestive peptidases
-
DOI 10.1016/j.pt.2004.03.004, PII S1471492204000777
-
C.R. Caffrey, J.H. McKerrow, J.P. Salter, and M. Sajid Blood 'n' guts: an update on schistosome digestive peptidases Trends Parasitol 20 2004 241 248 (Pubitemid 38510321)
-
(2004)
Trends in Parasitology
, vol.20
, Issue.5
, pp. 241-248
-
-
Caffrey, C.R.1
McKerrow, J.H.2
Salter, J.P.3
Sajid, M.4
-
66
-
-
0030879653
-
Hemoglobin metabolism in the malaria parasite Plasmodium falciparium
-
DOI 10.1146/annurev.micro.51.1.97
-
S.E. Francis, D.J. Sullivan Jr., and D.E. Goldberg Hemoglobin metabolism in the malaria parasite Plasmodium falciparum Ann Rev Microbiol 51 1997 97 123 (Pubitemid 27433044)
-
(1997)
Annual Review of Microbiology
, vol.51
, pp. 97-123
-
-
Francis, S.E.1
Sullivan Jr., D.J.2
Goldberg, D.E.3
-
67
-
-
0036718532
-
Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity
-
A.L. Williamson, P.J. Brindley, G. Abbenante, P. Prociv, C. Berry, and K. Girdwood Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity FASEB J 16 2002 1458 1460
-
(2002)
FASEB J
, vol.16
, pp. 1458-1460
-
-
Williamson, A.L.1
Brindley, P.J.2
Abbenante, G.3
Prociv, P.4
Berry, C.5
Girdwood, K.6
-
68
-
-
0037312504
-
Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion
-
DOI 10.1086/367708
-
A.L. Williamson, P.J. Brindley, G. Abbenante, B.J. Datu, P. Prociv, and C. Berry Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion J Infect Dis 187 2003 484 494 (Pubitemid 36184590)
-
(2003)
Journal of Infectious Diseases
, vol.187
, Issue.3
, pp. 484-494
-
-
Williamson, A.L.1
Brindley, P.J.2
Abbenante, G.3
Datu, B.J.D.4
Prociv, P.5
Berry, C.6
Girdwood, K.7
Pritchard, D.I.8
Fairlie, D.P.9
Hotez, P.J.10
Zhan, B.11
Loukas, A.12
-
69
-
-
50049136204
-
A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus
-
N. Ranjit, B. Zhan, D.J. Stenzel, J. Mulvenna, R. Fujiwara, and P.J. Hotez A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus Mol Biochem Parasitol 160 2008 90 99
-
(2008)
Mol Biochem Parasitol
, vol.160
, pp. 90-99
-
-
Ranjit, N.1
Zhan, B.2
Stenzel, D.J.3
Mulvenna, J.4
Fujiwara, R.5
Hotez, P.J.6
-
70
-
-
0026437469
-
Metabolism of lipid peroxidation products by the gastro-intestinal nematodes Necator americanus, Ancylostoma ceylanicum and Heligmosomoides polygyrus
-
P.M. Brophy, and D.I. Pritchard Metabolism of lipid peroxidation products by the gastro-intestinal nematodes Necator americanus, Ancylostoma ceylanicum and Heligmosomoides polygyrus Int J Parasitol 22 1992 1009 1012
-
(1992)
Int J Parasitol
, vol.22
, pp. 1009-1012
-
-
Brophy, P.M.1
Pritchard, D.I.2
-
71
-
-
25444502978
-
Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum
-
DOI 10.1128/IAI.73.10.6903-6911.2005
-
B. Zhan, S. Liu, S. Perally, J. Xue, R. Fujiwara, and P. Brophy Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum Infect Immun 73 2005 6903 6911 (Pubitemid 41368859)
-
(2005)
Infection and Immunity
, vol.73
, Issue.10
, pp. 6903-6911
-
-
Zhan, B.1
Liu, S.2
Perally, S.3
Xue, J.4
Fujiwara, R.5
Brophy, P.6
Xiao, S.7
Liu, Y.8
Feng, J.9
Williamson, A.10
Wang, Y.11
Bueno, L.L.12
Mendez, S.13
Goud, G.14
Bethony, J.M.15
Hawdon, J.M.16
Loukas, A.17
Jones, K.18
Hotez, P.J.19
-
72
-
-
77950278221
-
Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus
-
B. Zhan, S. Perally, P.M. Brophy, J. Xue, G. Goud, and S. Liu Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus Infect Immun 78 2010 1552 1563
-
(2010)
Infect Immun
, vol.78
, pp. 1552-1563
-
-
Zhan, B.1
Perally, S.2
Brophy, P.M.3
Xue, J.4
Goud, G.5
Liu, S.6
-
73
-
-
34447571783
-
X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus
-
O.A. Asojo, K. Homma, M. Sedlacek, M. Ngamelue, G.N. Goud, and B. Zhan X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus BMC Struct Biol 7 2007 42
-
(2007)
BMC Struct Biol
, vol.7
, pp. 42
-
-
Asojo, O.A.1
Homma, K.2
Sedlacek, M.3
Ngamelue, M.4
Goud, G.N.5
Zhan, B.6
-
74
-
-
37349102676
-
The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus
-
DOI 10.1016/j.exppara.2007.05.010, PII S0014489407001609
-
S. Xiao, B. Zhan, J. Xue, G.N. Goud, A. Loukas, and Y. Liu The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus Exp Parasitol 118 2008 32 40 (Pubitemid 350299333)
-
(2008)
Experimental Parasitology
, vol.118
, Issue.1
, pp. 32-40
-
-
Xiao, S.1
Zhan, B.2
Xue, J.3
Goud, G.N.4
Loukas, A.5
Liu, Y.6
Williamson, A.7
Liu, S.8
Deumic, V.9
Hotez, P.10
-
75
-
-
0025330875
-
Glutathione transferase in helminths
-
P.M. Brophy, and J. Barrett Glutathione transferase in helminths Parasitology 100 1990 345 349 (Pubitemid 20168031)
-
(1990)
Parasitology
, vol.100
, Issue.2
, pp. 345-349
-
-
Brophy, P.M.1
Barrett, J.2
-
76
-
-
55949089700
-
Heme transport and detoxification in nematodes: Subproteomics evidence of differential role of glutathione transferases
-
S. Perally, E.J. Lacourse, A.M. Campbell, and P.M. Brophy Heme transport and detoxification in nematodes: subproteomics evidence of differential role of glutathione transferases J Proteome Res 7 2008 4557 4565
-
(2008)
J Proteome Res
, vol.7
, pp. 4557-4565
-
-
Perally, S.1
Lacourse, E.J.2
Campbell, A.M.3
Brophy, P.M.4
-
77
-
-
28644432297
-
Crystal structure of a new class of glutathione transferase from the model human hookworm nematode Heligmosomoides polygyrus
-
DOI 10.1002/prot.20649
-
D.J. Schuller, Q. Liu, I.A. Kriksunov, A.M. Campbell, J. Barrett, and P.M. Brophy Crystal structure of a new class of glutathione transferase from the model human hookworm nematode Heligmosomoides polygyrus Proteins 61 2005 1024 1031 (Pubitemid 41753170)
-
(2005)
Proteins: Structure, Function and Genetics
, vol.61
, Issue.4
, pp. 1024-1031
-
-
Schuller, D.J.1
Liu, Q.2
Kriksunov, I.A.3
Campbell, A.M.4
Barrett, J.5
Brophy, P.M.6
Hao, Q.7
-
78
-
-
0035062825
-
A common class of nematode glutathione S-transferase (GST) revealed by the theoretical proteome of the model organism Caenorhabditis elegans
-
DOI 10.1016/S1096-4959(00)00360-2, PII S1096495900003602
-
A.M. Campbell, P.H. Teesdale-Spittle, J. Barrett, E. Liebau, J.R. Jefferies, and P.M. Brophy A common class of nematode glutathione S-transferase (GST) revealed by the theoretical proteome of the model organism Caenorhabditis elegans Comp Biochem Physiol B Biochem Mol Biol 128 2001 701 708 (Pubitemid 32275998)
-
(2001)
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology
, vol.128
, Issue.4
, pp. 701-708
-
-
Campbell, A.M.1
Teesdale-Spittle, P.H.2
Barrett, J.3
Liebau, E.4
Jefferies, J.R.5
Brophy, P.M.6
-
79
-
-
2142695776
-
Binding of Hematin by a New Class of Glutathione Transferase from the Blood-Feeding Parasitic Nematode Haemonchus contortus
-
DOI 10.1128/IAI.72.5.2780-2790.2004
-
A.J. van Rossum, J.R. Jefferies, F.A. Rijsewijk, E.J. LaCourse, P. Teesdale-Spittle, and J. Barrett Binding of hematin by a new class of glutathione transferase from the blood-feeding parasitic nematode Haemonchus contortus Infect Immun 72 2004 2780 2790 (Pubitemid 38542406)
-
(2004)
Infection and Immunity
, vol.72
, Issue.5
, pp. 2780-2790
-
-
Van Rossum, A.J.1
Jefferies, J.R.2
Rijsewijk, F.A.M.3
LaCourse, E.J.4
Teesdale-Spittle, P.5
Barrett, J.6
Tait, A.7
Brophy, P.M.8
-
80
-
-
0023771061
-
Light, long-lasting Necator infection in a volunteer
-
P.C. Beaver Light, long-lasting Necator infection in a volunteer Am J Trop Med Hyg 39 1988 369 372
-
(1988)
Am J Trop Med Hyg
, vol.39
, pp. 369-372
-
-
Beaver, P.C.1
-
81
-
-
0034703067
-
A broad spectrum Kunitz type serine protease inhibitor secreted by the hookworm Ancylostoma ceylanicum
-
DOI 10.1074/jbc.M002715200
-
A.M. Milstone, L.M. Harrison, R.D. Bungiro, P. Kuzmic, and M. Cappello A broad spectrum Kunitz type serine protease inhibitor secreted by the hookworm Ancylostoma ceylanicum J Biol Chem 275 2000 29391 29399 (Pubitemid 32043812)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.38
, pp. 29391-29399
-
-
Milstone, A.M.1
Harrison, L.M.2
Bungiro, R.D.3
Kuzmic, P.4
Cappello, M.5
-
82
-
-
0012813996
-
The bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor): A milestone protein
-
DOI 10.2174/1389203033487180
-
P. Ascenzi, A. Bocedi, M. Bolognesi, A. Spallarossa, M. Coletta, and R. De Cristofaro The bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor): a milestone protein Curr Protein Pept Sci 4 2003 231 251 (Pubitemid 36656736)
-
(2003)
Current Protein and Peptide Science
, vol.4
, Issue.3
, pp. 231-251
-
-
Ascenzi, P.1
Bocedi, A.2
Bolognesi, M.3
Spallarossa, A.4
Colletta, M.5
De Cristofaro, R.6
Menegatti, E.7
-
83
-
-
79951770643
-
Identification and characterization of a serine protease inhibitor with two trypsin inhibitor-like domains from the human hookworm Ancylostoma duodenale
-
X. Jin, L. Deng, H. Li, Z. Zhang, Q. He, and C. Yang Identification and characterization of a serine protease inhibitor with two trypsin inhibitor-like domains from the human hookworm Ancylostoma duodenale Parasitol Res 108 2011 287 295
-
(2011)
Parasitol Res
, vol.108
, pp. 287-295
-
-
Jin, X.1
Deng, L.2
Li, H.3
Zhang, Z.4
He, Q.5
Yang, C.6
-
84
-
-
0037398198
-
Molecular cloning of a novel multidomain Kunitz-type proteinase inhibitor from the hookworm Ancylostoma caninum
-
DOI 10.1645/0022-3395(2003)089[0402:MCOANM]2.0.CO;2
-
J.M. Hawdon, B. Datu, and M. Crowell Molecular cloning of a novel multidomain Kunitz-type proteinase inhibitor from the hookworm Ancylostoma caninum J Parasitol 89 2003 402 407 (Pubitemid 36523241)
-
(2003)
Journal of Parasitology
, vol.89
, Issue.2
, pp. 402-407
-
-
Hawdon, J.M.1
Datu, B.2
Crowell, M.3
-
85
-
-
1842426271
-
Malnutrition in African adults. 5. Effects of hookworm infestation on absorption of foodstuffs
-
S.J. Dark Malnutrition in African adults. 5. Effects of hookworm infestation on absorption of foodstuffs Br J Nutr 13 1959 278 282
-
(1959)
Br J Nutr
, vol.13
, pp. 278-282
-
-
Dark, S.J.1
-
86
-
-
0014021867
-
Functional and structural studies of small bowel in ankylostomiasis
-
B.N. Tandon, B.C. Das, A.K. Saraya, and M.G. Deo Functional and structural studies of small bowel in ankylostomiasis BMJ 1 1966 714 716
-
(1966)
BMJ
, vol.1
, pp. 714-716
-
-
Tandon, B.N.1
Das, B.C.2
Saraya, A.K.3
Deo, M.G.4
-
87
-
-
1842431649
-
Molecular Characterization of Ancylostoma ceylanicum Kunitz-Type Serine Protease Inhibitor: Evidence for A Role in Hookworm-Associated Growth Delay
-
DOI 10.1128/IAI.72.4.2214-2221.2004
-
D. Chu, R.D. Bungiro, M. Ibanez, L.M. Harrison, E. Campodonico, and B.F. Jones Molecular characterization of Ancylostoma ceylanicum Kunitz-type serine protease inhibitor: evidence for a role in hookworm-associated growth delay Infect Immun 72 2004 2214 2221 (Pubitemid 38419936)
-
(2004)
Infection and Immunity
, vol.72
, Issue.4
, pp. 2214-2221
-
-
Chu, D.1
Bungiro Jr., R.D.2
Ibanez, M.3
Harrison, L.M.4
Campodonico, E.5
Jones, B.F.6
Mieszczanek, J.7
Kuzmic, P.8
Cappello, M.9
-
88
-
-
77953941153
-
Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network
-
C.A. Figueiredo, M.L. Barreto, L.C. Rodrigues, P.J. Cooper, N.B. Silva, and L.D. Amorim Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network Infect Immun 78 2010 3160 3167
-
(2010)
Infect Immun
, vol.78
, pp. 3160-3167
-
-
Figueiredo, C.A.1
Barreto, M.L.2
Rodrigues, L.C.3
Cooper, P.J.4
Silva, N.B.5
Amorim, L.D.6
-
89
-
-
77954644772
-
The immunology of human hookworm infections
-
H.J. McSorley, and A. Loukas The immunology of human hookworm infections Parasite Immunol 32 2010 549 559
-
(2010)
Parasite Immunol
, vol.32
, pp. 549-559
-
-
McSorley, H.J.1
Loukas, A.2
-
90
-
-
84859158485
-
T cells in helminth infection: The regulators and the regulated
-
M.D. Taylor, N. van der Werf, and R.M. Maizels T cells in helminth infection: the regulators and the regulated Trends Immunol 33 2012 181 189
-
(2012)
Trends Immunol
, vol.33
, pp. 181-189
-
-
Taylor, M.D.1
Van Der Werf, N.2
Maizels, R.M.3
-
91
-
-
34548174685
-
Structural and functional characterization of a secreted hookworm macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74
-
DOI 10.1074/jbc.M702950200
-
Y. Cho, B.F. Jones, J.J. Vermeire, L. Leng, L. DiFedele, and L.M. Harrison Structural and functional characterization of a secreted hookworm Macrophage Migration Inhibitory Factor (MIF) that interacts with the human MIF receptor CD74 J Biol Chem 282 2007 23447 23456 (Pubitemid 47311922)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.32
, pp. 23447-23456
-
-
Cho, Y.1
Jones, B.F.2
Vermeire, J.J.3
Leng, L.4
DiFedele, L.5
Harrison, L.M.6
Xiong, H.7
Kwong, Y.-K.A.8
Chen, Y.9
Bucala, R.10
Lolis, E.11
Cappello, M.12
-
92
-
-
0141862287
-
Recombinant nematode anticoagulant protein c2 and other inhibitors targeting blood coagulation factor VIIa/tissue factor
-
DOI 10.1046/j.1365-2796.2003.01224.x
-
A.Y. Lee, and G.P. Vlasuk Recombinant nematode anticoagulant protein c2 and other inhibitors targeting blood coagulation factor VIIa/tissue factor J Intern Med 254 2003 313 321 (Pubitemid 37211255)
-
(2003)
Journal of Internal Medicine
, vol.254
, Issue.4
, pp. 313-321
-
-
Lee, A.Y.Y.1
Vlasuk, G.P.2
-
93
-
-
0030856003
-
Antithrombotic efficacy of a recombinant nematode anticoagulant peptide (rNAP5) in canine models of thrombosis after single subcutaneous administration
-
S.S. Rebello, H.S. Blank, W.E. Rote, G.P. Vlasuk, and B.R. Lucchesi Antithrombotic efficacy of a recombinant nematode anticoagulant peptide (rNAP5) in canine models of thrombosis after single subcutaneous administration J Pharmacol Exp Ther 283 1997 91 99 (Pubitemid 27438950)
-
(1997)
Journal of Pharmacology and Experimental Therapeutics
, vol.283
, Issue.1
, pp. 91-99
-
-
Rebello, S.S.1
Blank, H.S.2
Rote, W.E.3
Vlasuk, G.P.4
Lucchesi, B.R.5
-
94
-
-
0029584119
-
Neutrophil inhibitory factor is neuroprotective after focal ischemia in rats
-
DOI 10.1002/ana.410380615
-
N. Jiang, M. Moyle, H.R. Soule, W.E. Rote, and M. Chopp Neutrophil inhibitory factor is neuroprotective after focal ischemia in rats Ann Neurol 38 1995 935 942 (Pubitemid 26004599)
-
(1995)
Annals of Neurology
, vol.38
, Issue.6
, pp. 935-942
-
-
Jiang, N.1
Moyle, M.2
Soule, H.R.3
Rote, W.E.4
Chopp, M.5
-
95
-
-
0028811225
-
Neutrophil inhibitory factor prevents neutrophil-dependent lung injury
-
J.W. Barnard, M.G. Biro, S.K. Lo, S. Ohno, M.A. Carozza, and M. Moyle Neutrophil inhibitory factor prevents neutrophil-dependent lung injury J Immunol 155 1995 4876 4881
-
(1995)
J Immunol
, vol.155
, pp. 4876-4881
-
-
Barnard, J.W.1
Biro, M.G.2
Lo, S.K.3
Ohno, S.4
Carozza, M.A.5
Moyle, M.6
-
97
-
-
31344458952
-
Structure and function of matrix metalloproteinases and TIMPs
-
DOI 10.1016/j.cardiores.2005.12.002, PII S0008636305005651
-
H. Nagase, R. Visse, and G. Murphy Structure and function of matrix metalloproteinases and TIMPs Cardiovasc Res 69 2006 562 573 (Pubitemid 43139720)
-
(2006)
Cardiovascular Research
, vol.69
, Issue.3
, pp. 562-573
-
-
Nagase, H.1
Visse, R.2
Murphy, G.3
-
98
-
-
0036318078
-
Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms
-
B. Zhan, M. Badamchian, B. Meihua, J. Ashcom, J. Feng, and J. Hawdon Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms Am J Trop Med Hyg 66 2002 238 244 (Pubitemid 34756090)
-
(2002)
American Journal of Tropical Medicine and Hygiene
, vol.66
, Issue.3
, pp. 238-244
-
-
Zhan, B.1
Badamchian, M.2
Meihua, B.3
Ashcom, J.4
Feng, J.5
Hawdon, J.6
Shuhua, X.7
Hotez, P.J.8
-
99
-
-
54049129199
-
Molecular cloning and characterization of Ac-TMP-2, a tissue inhibitor of metalloproteinase secreted by adult Ancylostoma caninum
-
B. Zhan, R. Gupta, S.P. Wong, S. Bier, D. Jiang, and G. Goud Molecular cloning and characterization of Ac-TMP-2, a tissue inhibitor of metalloproteinase secreted by adult Ancylostoma caninum Mol Biochem Parasitol 162 2008 142 148
-
(2008)
Mol Biochem Parasitol
, vol.162
, pp. 142-148
-
-
Zhan, B.1
Gupta, R.2
Wong, S.P.3
Bier, S.4
Jiang, D.5
Goud, G.6
-
100
-
-
77949329252
-
The hookworm tissue inhibitor of metalloproteases (Ac-TMP-1) modifies dendritic cell function and induces generation of CD4 and CD8 suppressor T cells
-
C. Cuellar, W. Wu, and S. Mendez The hookworm tissue inhibitor of metalloproteases (Ac-TMP-1) modifies dendritic cell function and induces generation of CD4 and CD8 suppressor T cells PLoS Negl Trop Dis 3 2009 e439
-
(2009)
PLoS Negl Trop Dis
, vol.3
, pp. 439
-
-
Cuellar, C.1
Wu, W.2
Mendez, S.3
-
101
-
-
1842484056
-
Purification and Molecular Cloning of and Immunization with Ancylostoma ceylanicum Excretory-Secretory Protein 2, An Immunoreactive Protein Produced by Adult Hookworms
-
DOI 10.1128/IAI.72.4.2203-2213.2004
-
R.D. Bungiro Jr., C.V. Solis, L.M. Harrison, and M. Cappello Purification and molecular cloning of and immunization with Ancylostoma ceylanicum excretory-secretory protein 2, an immunoreactive protein produced by adult hookworms Infect Immun 72 2004 2203 2213 (Pubitemid 38419935)
-
(2004)
Infection and Immunity
, vol.72
, Issue.4
, pp. 2203-2213
-
-
Bungiro Jr., R.D.1
Solis, C.V.2
Harrison, L.M.3
Cappello, M.4
-
102
-
-
79953236271
-
Ancylostoma ceylanicum excretory-secretory protein 2 adopts a netrin-like fold and defines a novel family of nematode proteins
-
K. Kucera, L.M. Harrison, M. Cappello, and Y. Modis Ancylostoma ceylanicum excretory-secretory protein 2 adopts a netrin-like fold and defines a novel family of nematode proteins J Mol Biol 408 2011 9 17
-
(2011)
J Mol Biol
, vol.408
, pp. 9-17
-
-
Kucera, K.1
Harrison, L.M.2
Cappello, M.3
Modis, Y.4
-
103
-
-
0037134046
-
Allergy, parasites, and the hygiene hypothesis
-
M. Yazdanbakhsh, P.G. Kremsner, and R. van Ree Allergy, parasites, and the hygiene hypothesis Science 296 2002 490 494
-
(2002)
Science
, vol.296
, pp. 490-494
-
-
Yazdanbakhsh, M.1
Kremsner, P.G.2
Van Ree, R.3
-
104
-
-
80054745689
-
Hookworm products ameliorate dextran sodium sulfate-induced colitis in BALB/c mice
-
G.G. Cancado, J.A. Fiuza, N.C. de Paiva, C. Lemos Lde, N.D. Ricci, and P.H. Gazzinelli-Guimaraes Hookworm products ameliorate dextran sodium sulfate-induced colitis in BALB/c mice Inflamm Bowel Dis 17 2011 2275 2286
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 2275-2286
-
-
Cancado, G.G.1
Fiuza, J.A.2
De Paiva, N.C.3
Lemos Lde, C.4
Ricci, N.D.5
Gazzinelli-Guimaraes, P.H.6
-
105
-
-
80052868010
-
Suppression of inflammatory immune responses in celiac disease by experimental hookworm infection
-
H.J. McSorley, S. Gaze, J. Daveson, D. Jones, R.P. Anderson, and A. Clouston Suppression of inflammatory immune responses in celiac disease by experimental hookworm infection PLoS One 6 2011 e24092
-
(2011)
PLoS One
, vol.6
, pp. 24092
-
-
McSorley, H.J.1
Gaze, S.2
Daveson, J.3
Jones, D.4
Anderson, R.P.5
Clouston, A.6
-
106
-
-
67650134618
-
Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice
-
N.E. Ruyssers, B.Y. De Winter, J.G. De Man, A. Loukas, M.S. Pearson, and J.V. Weinstock Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice Inflamm Bowel Dis 15 2009 491 500
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 491-500
-
-
Ruyssers, N.E.1
De Winter, B.Y.2
De Man, J.G.3
Loukas, A.4
Pearson, M.S.5
Weinstock, J.V.6
-
107
-
-
79952427391
-
Effect of hookworm infection on wheat challenge in celiac disease - A randomised double-blinded placebo controlled trial
-
A.J. Daveson, D.M. Jones, S. Gaze, H. McSorley, A. Clouston, and A. Pascoe Effect of hookworm infection on wheat challenge in celiac disease - a randomised double-blinded placebo controlled trial PLoS One 6 2011 e17366
-
(2011)
PLoS One
, vol.6
, pp. 17366
-
-
Daveson, A.J.1
Jones, D.M.2
Gaze, S.3
McSorley, H.4
Clouston, A.5
Pascoe, A.6
-
108
-
-
84860276395
-
Characterising the mucosal and systemic immune responses to experimental human hookworm infection
-
S. Gaze, H.J. McSorley, J. Daveson, D. Jones, J.M. Bethony, and L.M. Oliveira Characterising the mucosal and systemic immune responses to experimental human hookworm infection PLoS Pathog 8 2012 e1002520
-
(2012)
PLoS Pathog
, vol.8
, pp. 1002520
-
-
Gaze, S.1
McSorley, H.J.2
Daveson, J.3
Jones, D.4
Bethony, J.M.5
Oliveira, L.M.6
-
109
-
-
70349324805
-
An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection
-
M.S. Pearson, J.M. Bethony, D.A. Pickering, L.M. de Oliveira, A. Jariwala, and H. Santiago An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection FASEB J 23 2009 3007 3019
-
(2009)
FASEB J
, vol.23
, pp. 3007-3019
-
-
Pearson, M.S.1
Bethony, J.M.2
Pickering, D.A.3
De Oliveira, L.M.4
Jariwala, A.5
Santiago, H.6
-
110
-
-
33750157972
-
Hookworm vaccines: Past, present, and future
-
DOI 10.1016/S1473-3099(06)70630-2, PII S1473309906706302
-
A. Loukas, J. Bethony, S. Brooker, and P. Hotez Hookworm vaccines: past, present, and future Lancet Infect Dis 6 2006 733 741 (Pubitemid 44601993)
-
(2006)
Lancet Infectious Diseases
, vol.6
, Issue.11
, pp. 733-741
-
-
Loukas, A.1
Bethony, J.2
Brooker, S.3
Hotez, P.4
-
111
-
-
77955933088
-
Blunting the knife: Development of vaccines targeting digestive proteases of blood-feeding helminth parasites
-
M.S. Pearson, N. Ranjit, and A. Loukas Blunting the knife: development of vaccines targeting digestive proteases of blood-feeding helminth parasites Biol Chem 391 2010 901 911
-
(2010)
Biol Chem
, vol.391
, pp. 901-911
-
-
Pearson, M.S.1
Ranjit, N.2
Loukas, A.3
-
112
-
-
80052709811
-
Vaccinomics for the major blood feeding helminths of humans
-
A. Loukas, S. Gaze, J.P. Mulvenna, R.B. Gasser, P.J. Brindley, and D.L. Doolan Vaccinomics for the major blood feeding helminths of humans OMICS 15 2011 567 577
-
(2011)
OMICS
, vol.15
, pp. 567-577
-
-
Loukas, A.1
Gaze, S.2
Mulvenna, J.P.3
Gasser, R.B.4
Brindley, P.J.5
Doolan, D.L.6
|