A pore-forming haemolysin from the hookworm, Ancylostoma caninum

International Journal for Parasitology

Volumn 34, Issue 9, 2004, Pages 1029-1035

  Don, Tegan A ^a,b   Jones, Malcolm K ^a,b   Smyth, Danielle ^a   O'Donoghue, Peter ^b   Hotez, Peter ^c   Loukas, Alex ^a,b,c  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Ancylostoma caninum; Erythrocyte; Haemolysin; Hookworm; Pore former

Indexed keywords

BUFFER; CHELATING AGENT; DETERGENT; HEMOLYSIN; HEMOLYTIC AGENT; METAL ION; PROTEIN; PROTEINASE INHIBITOR; REDUCING AGENT; TRYPSIN;

NEMATODE; PARASITOLOGY;

ADULTHOOD; ANCYLOSTOMA CANINUM; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BIOTINYLATION; CELL DISRUPTION; CONTROLLED STUDY; CYTOLYSIS; DEVELOPMENTAL STAGE; DOG; ERYTHROCYTE GHOST; ERYTHROCYTE MEMBRANE; HEMOLYSIS; HOOKWORM; HUMAN; HUMAN CELL; ION EXCHANGE CHROMATOGRAPHY; LARVA; MEMBRANE BINDING; MOLECULAR WEIGHT; NONHUMAN; OSMOSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN TRANSPORT; SCANNING ELECTRON MICROSCOPY; SOLUBILITY; THERMOSTABILITY;

ANCYLOSTOMA; ANIMALS; CELLS, CULTURED; CHROMATOGRAPHY, ION EXCHANGE; DOGS; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; HEMOLYSIN PROTEINS; HEMOLYSIS; MICROSCOPY, ELECTRON, SCANNING; OSMOTIC FRAGILITY;

ANCYLOSTOMA; ANCYLOSTOMA CANINUM; ANCYLOSTOMATOIDEA; CANIS FAMILIARIS;

EID: 4143084912     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2004.04.013     Document Type: Article

References (35)

1. Amino R., Martins R.M., Procopio J., Hirata I.Y., Juliano M.A., Schenkman S. Trialysin, a novel pore-forming protein from saliva of hematophagous insects activated by limited proteolysis. J. Biol. Chem. 277:2002;6207-6213
2. Bass E.L., Pinion J.P., Sharif M.E. Characteristics of a hemolysin from Gonyaulax monilata. Aquat. Toxicol. 3:1983;15-22
3. Brindley P.J., Kalinna B.H., Wong J.Y., Bogitsh B.J., King L.T., Smyth D.J., Verity C.K., Abbenante G., Brinkworth R.I., Fairlie D.P., Smythe M.L., Milburn P.J., Bielefeldt-Ohmann H., Zheng Y., McManus D.P. Proteolysis of human hemoglobin by schistosome cathepsin D. Mol. Biochem. Parasitol. 112:2001;103-112
4. Carroll S.M., Proyor J., Kennett D.W., Grove D.I. Investigation of the haemolytic effects of Ancylostoma ceylanicum: observations on infected dogs in vivo and human and dog blood in vitro. Southeast Asian J. Trop. Med. Public Health. 15:1984;129-134
5. Costa H., Palma M.S. Agelotoxin: a phospholipase A(2) from the venom of the neotropical social wasp cassununga (Agelaia pallipes pallipes) (Hymenoptera-Vespidae). Toxicon. 38:2000;1367-1379
6. de Azambuja P., Guimaraest J.A., Garcia E.S. Haemolytic factor from the crop of Rhodnius prolixus: evidence and partial characterization. J. Insect Physiol. 29:1983;833-837
7. de Silva N.R., Brooker S., Hotez P.J., Montresor A., Engels D., Savioli L. Soil-transmitted helminth infections: updating the global picture. Trends Parasitol. 19:2003;547-551
8. Espino A.M., Hillyer G.V. Molecular cloning of a member of the Fasciola hepatica saposin-like protein family. J. Parasitol. 89:2003;545-552
9. Fetterer R.H., Rhoads M.L. Characterization of haemolytic activity from adult Haemonchus contortus. Int. J. Parasitol. 27:1997;1037-1040
10. Fetterer R.H., Rhoads M.L. A hemolytic factor from Haemonchus contortus alters erythrocyte morphology. Vet. Parasitol. 80:1998;37-45
11. Fiori P.L., Rappelli P., Addis M.F., Sechi A., Cappuccinelli P. Trichomonas vaginalis haemolysis: pH regulates a contact-independent mechanism based on pore-forming proteins. Microb. Pathog. 20:1996;109-118
12. Glupov V.V. Cell-mediated haemolytic activity of haemolymph from the Colorado potato beetle (Leptinotarsa decemlineata Say.). Cytobios. 86:1996;35-51
13. Gooding R.H. Digestive processes of haematophagous insects. XIV. Haemolytic activity in the midgut of Glossina morsitans morsitans Westwood (Diptera: Glossinidae). Can. J. Zool. 55:1905;1899-1905
14. Harrop S.A., Sawangjaroen N., Prociv P., Brindley P.J. Characterization and localization of cathepsin B proteinases expressed by adult Ancylostoma caninum hookworms. Mol. Biochem. Parasitol. 71:1995;163-171
15. Hawdon J.M., Schad G.A. Serum-stimulated feeding in vitro by third-stage infective larvae of the canine hookworm, Ancylostoma caninum. J. Parasitol. 76:1990;394-398
16. Kasschau M.R., Dresden M.H. Schistosoma mansoni: characterization of hemolytic activity from adult worms. Exp. Parasitol. 61:1986;201-209
17. Lee J.Y., Cho P.Y., Kim T.Y., Kang S.Y., Song K.Y., Hong S.J. Hemolytic activity and developmental expression of pore-forming peptide, clonorin. Biochem. Biophys. Res. Commun. 296:2002;1238-1244
18. Ley V., Robbins E.S., Nussenzweig V., Andrews N.W. The exit of Trypanosoma cruzi from the phagosome is inhibited by raising the pH of acidic compartments. J. Exp. Med. 171:1990;401-413
19. Loeb L., Fleisher M.S. The influence of extracts of Ancylostoma caninum on the coagulation of the blood and on haemolysis. J. Infect. Dis. 7:1910;625-631
20. Loukas A., Croese J., Opdebeeck J., Prociv P. Detection of antibodies to secretions of Ancylostoma caninum in human eosinophilic enteritis. Trans. R. Soc. Trop. Med. Hyg. 86:1992;650-653
21. Loukas A., Bethony J., Williamson A., Goud G., Mendez S., Zhan B., Hawdon J.M., Bottazzi M.E., Brindley P.J., Hotez P. Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes fecundity and growth of worms. J. Infect. Dis. 2004;. 189, 1952-61
22. Nagao E., Yamamoto A., Igarashi T., Goto N., Sasa R. Two distinct hemolysins in Trichomonas tenax ATCC 30207. Oral Microbiol. Immunol. 15:2000;355-359
23. Noronha F.S., Ramalho-Pinto F.J., Horta M.F. Identification of a putative pore-forming hemolysin active at acid pH in Leishmania amazonensis. Braz. J. Med. Biol. Res. 27:1994;477-482
24. O'Daly J.A., Aso P.M. Trypanosoma cruzi, Leishmania donovani, and L. mexicana: extract factor that lyses mammalian cells. Exp. Parasitol. 47:1979;222-231
25. Ojcius D.M., Thibon M., Mounier C., Dautry-Varsat A. pH and calcium dependence of hemolysis due to Rickettsia prowazekii: comparison with phospholipase activity. Infect. Immun. 63:1995;3069-3072
26. Roche M., Layrisse M. The nature and causes of hookworm anemia. Am. J. Trop. Med. Hyg. 15:1966;1031-1102
27. Roggwiller E., Blisnick T., Braun Breton C. A Plasmodium falciparum hemolytic activity. Mol. Biochem. Parasitol. 94:1998;303-307
28. Rosales-Encina J.L., Schlie-Guzman M.A., Jimenez-Delgadillo B., Talamas-Rohana P., Matluk M.R. Purification and partial characterization of an hemolytic activity from Entamoeba histolytica. Arch. Med. Res. 23:1992;243-248
29. Whipple G.H. The presence of a weak hemolysin in the hook worm and its relation to the anemia of uncinariasis. J. Exp. Med. 11:1909;331-343
30. Williamson A.L., Brindley P.J., Abbenante G., Prociv P., Berry C., Girdwood K., Pritchard D.I., Fairlie D.P., Hotez P.J., Dalton J.P., Loukas A. Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. Fed. Am. Soc. Exp. Biol. J. 16:2002;1458-1460
31. Williamson A.L., Brindley P.J., Abbenante G., Datu B.J., Prociv P., Berry C., Girdwood K., Pritchard D.I., Fairlie D.P., Hotez P.J., Zhan B., Loukas A. Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. J. Infect. Dis. 187:2003;484-494
32. Williamson A.L., Brindley P.J., Knox D.P., Hotez P.J., Loukas A. Digestive proteases of blood-feeding nematodes. Trends Parasitol. 19:2003;417-423
33. Young J.D., Lowrey D.M. Biochemical and functional characterization of a membrane-associated pore-forming protein from the pathogenic ameboflagellate Naegleria fowleri. J. Biol. Chem. 264:1989;1077-1083
34. Young J.D., Young T.M., Lu L.P., Unkeless J.C., Cohn Z.A. Characterization of a membrane pore-forming protein from Entamoeba histolytica. J. Exp. Med. 156:1982;1677-1690
35. Zhai Y., Saier M.H. Jr. The amoebapore superfamily. Biochim. Biophys. Acta. 1469:2000;87-99