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Volumn 177, Issue 1, 2011, Pages 42-48

Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum

Author keywords

Ancylostoma caninum; Anticoagulant; fXa; Vaccine

Indexed keywords

ANCYLOSTOMA CANINUM ANTICOAGULANT PEPTIDE 12; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; BLOOD CLOTTING FACTOR 7A; COMPLEMENTARY DNA; MESSENGER RNA; RABBIT ANTISERUM; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 79952446683     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2011.01.008     Document Type: Article
Times cited : (19)

References (40)
  • 2
    • 33646180655 scopus 로고    scopus 로고
    • Soil-transmitted helminth infections: Ascariasis, trichuriasis, and hookworm
    • J. Bethony, S. Brooker, and M. Albonico Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm Lancet 367 2006 1521 1532
    • (2006) Lancet , vol.367 , pp. 1521-1532
    • Bethony, J.1    Brooker, S.2    Albonico, M.3
  • 3
    • 0013965976 scopus 로고
    • Nature and causes of "hookworm anemia"
    • M. Roche, and M. Layrisse Nature and causes of "hookworm anemia" Am J Trop Med Hyg 15 1966 1029 1102
    • (1966) Am J Trop Med Hyg , vol.15 , pp. 1029-1102
    • Roche, M.1    Layrisse, M.2
  • 6
    • 0000386699 scopus 로고
    • The presence of a substance inhibiting coagulation of blood in Ancylostoma
    • L. Loeb, and A.J. Smith The presence of a substance inhibiting coagulation of blood in Ancylostoma Proc Path Soc Phil 7 1904 173 178
    • (1904) Proc Path Soc Phil , vol.7 , pp. 173-178
    • Loeb, L.1    Smith, A.J.2
  • 7
    • 0000033507 scopus 로고
    • The influence of extracts of Ancylostoma caninum on the coagulation of the blood and hemolysis
    • L. Loeb, and M.S. Feisher The influence of extracts of Ancylostoma caninum on the coagulation of the blood and hemolysis J Infect Dis 7 1910 625 631
    • (1910) J Infect Dis , vol.7 , pp. 625-631
    • Loeb, L.1    Feisher, M.S.2
  • 8
    • 0002059250 scopus 로고
    • The effect of extracts of the amphidial glands excretory glands, and esophagus of adults of Ancylostoma caninum on the coagulation of dogs blood
    • R.E. Thorson The effect of extracts of the amphidial glands excretory glands, and esophagus of adults of Ancylostoma caninum on the coagulation of dogs blood J Parasitol 42 1 1956 26 30
    • (1956) J Parasitol , vol.42 , Issue.1 , pp. 26-30
    • Thorson, R.E.1
  • 9
    • 0013954778 scopus 로고
    • Nature of an anticoagulant from the cephalic glands of Ancylostoma caninum
    • J.A. Eiff Nature of an anticoagulant from the cephalic glands of Ancylostoma caninum J Parasitol 52 1966 833 843
    • (1966) J Parasitol , vol.52 , pp. 833-843
    • Eiff, J.A.1
  • 10
    • 0029014045 scopus 로고
    • Ancylostoma caninum anticoagulant peptide: A hookworm-derived inhibitor of human coagulation factor Xa
    • M. Cappello, G.P. Vlasuk, P.W. Bergum, S. Huang, and Hotez PJ Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa Proc Natl Acad Sci USA 92 1995 6152 6156
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6152-6156
    • Cappello, M.1    Vlasuk, G.P.2    Bergum, P.W.3    Huang, S.4    Hotez, P.J.5
  • 12
    • 0038015446 scopus 로고    scopus 로고
    • Isolation and molecular cloning of a secreted hookworm platelet inhibitor from adult Ancylostoma caninum
    • DOI 10.1016/S0166-6851(03)00121-X
    • A. Del Valle, B.F. Jones, L.M. Harrison, R.C. Chadderdon, and M. Cappello Isolation and molecular cloning of a secreted hookworm platelet inhibitor from adult Ancylostoma caninum Mol Biochem Parasitol 129 2003 167 177 (Pubitemid 36794569)
    • (2003) Molecular and Biochemical Parasitology , vol.129 , Issue.2 , pp. 167-177
    • Del Valle, A.1    Jones, B.F.2    Harrison, L.M.3    Chadderdon, R.C.4    Cappello, M.5
  • 13
    • 0033013065 scopus 로고    scopus 로고
    • 1) inhibits platelet aggregation and adhesion in vitro
    • DOI 10.1086/314724
    • R.C. Chadderdon, and M. Cappello The hookworm platelet inhibitor: functional blockade of integrins GPIIb/IIIa (alphaIIbbeta3) and GPIa/IIa (alpha2beta1) inhibits platelet aggregation and adhesion in vitro J Infect Dis 179 1999 1235 1241 (Pubitemid 29196506)
    • (1999) Journal of Infectious Diseases , vol.179 , Issue.5 , pp. 1235-1241
    • Chadderdon, R.C.1    Cappello, M.2
  • 14
    • 0027155257 scopus 로고
    • Ancylostoma factor Xa inhibitor: Partial purification and its identification as a major hookworm-derived anticoagulant in vitro
    • M. Cappello, L.P. Clyne, P. McPhedran, and P.J. Hotez Ancylostoma factor Xa inhibitor: partial purification and its identification as a major hookworm-derived anticoagulant in vitro J Infect Dis 167 1993 1474 1477 (Pubitemid 23146209)
    • (1993) Journal of Infectious Diseases , vol.167 , Issue.6 , pp. 1474-1477
    • Cappello, M.1    Clyne, L.P.2    McPhedran, P.3    Hotez, P.J.4
  • 15
    • 0030249127 scopus 로고    scopus 로고
    • Ancylostoma caninum anticoagulant peptide: Cloning by PCR and expression of soluble, active protein in E. coli
    • DOI 10.1016/0166-6851(96)02658-8
    • M. Cappello, J.M. Hawdon, B.F. Jones, W.P. Kennedy, and P.J. Hotez Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli Mol Biochem Parasitol 80 1996 113 117 (Pubitemid 26284391)
    • (1996) Molecular and Biochemical Parasitology , vol.80 , Issue.1 , pp. 113-117
    • Cappello, M.1    Hawdon, J.M.2    Jones, B.F.3    Kennedy, W.P.4    Hotez, P.J.5
  • 16
    • 0035007328 scopus 로고    scopus 로고
    • Ancylostoma caninum anticoagulant peptide-5: Immunolocalization and in vitro neutralization of a major hookworm anti-thrombotic
    • DOI 10.1016/S0166-6851(01)00276-6, PII S0166685101002766
    • L.M. Harrison, J.L. Cordova, and M. Cappello Ancylostoma caninum anticoagulant peptide-5: immunolocalization and in vitro neutralization of a major hookworm anti-thrombotic Mol Biochem Parasitol 115 2001 101 107 (Pubitemid 32493857)
    • (2001) Molecular and Biochemical Parasitology , vol.115 , Issue.1 , pp. 101-107
    • Harrison, L.M.1    Cordova, J.L.2    Cappello, M.3
  • 17
    • 75749103376 scopus 로고    scopus 로고
    • Identification of an anticoagulant peptide that inhibits both fXIa and fVIIa/tissue factor from the blood-feeding nematode Ancylostoma caninum
    • D. Li, Q. He, and T. Kang Identification of an anticoagulant peptide that inhibits both fXIa and fVIIa/tissue factor from the blood-feeding nematode Ancylostoma caninum Biochem Biophys Res Commun 392 2 2010 155 159
    • (2010) Biochem Biophys Res Commun , vol.392 , Issue.2 , pp. 155-159
    • Li, D.1    He, Q.2    Kang, T.3
  • 18
    • 0037155248 scopus 로고    scopus 로고
    • Molecular characterization of Ancylostoma inhibitors of coagulation factor Xa. Hookworm anticoagulant activity in vitro predicts parasite bloodfeeding in vivo
    • DOI 10.1074/jbc.M109908200
    • L.M. Harrison, A. Nerlinger, R.D. Bungiro, J.L. Cordova, P. Kuzmic, and M. Cappello Molecular characterization of Ancylostoma inhibitors of coagulation factor Xa. Hookworm anticoagulant activity in vitro predicts parasite bloodfeeding in vivo J Biol Chem 277 2002 6223 6229 (Pubitemid 34968413)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.8 , pp. 6223-6229
    • Harrison, L.M.1    Nerlinger, A.2    Bungiro, R.D.3    Cordova, J.L.4    Kuzmic, P.5    Cappello, M.6
  • 19
    • 3342988385 scopus 로고    scopus 로고
    • Ancylostoma ceylanicum anticoagulant peptide-1: Role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa
    • DOI 10.1016/j.molbiopara.2004.05.011, PII S0166685104001550
    • J. Mieszczanek, L.M. Harrison, and M. Cappello Ancylostoma ceylanicum anticoagulant peptide-1: role of the predicted reactive site amino acid in mediating inhibition of coagulation factors Xa and VIIa Mol Biochem Parasitol 137 1 2004 151 159 (Pubitemid 38987952)
    • (2004) Molecular and Biochemical Parasitology , vol.137 , Issue.1 , pp. 151-159
    • Mieszczanek, J.1    Harrison, L.M.2    Cappello, M.3
  • 20
    • 67349125443 scopus 로고    scopus 로고
    • An anticoagulant peptide from the human hookworm Ancylostoma duodenale that inhibits coagulation factors Xa and XIa
    • W. Gan, L. Deng, and C. Yang An anticoagulant peptide from the human hookworm Ancylostoma duodenale that inhibits coagulation factors Xa and XIa FEBS Lett 583 12 2009 1976 1980
    • (2009) FEBS Lett , vol.583 , Issue.12 , pp. 1976-1980
    • Gan, W.1    Deng, L.2    Yang, C.3
  • 22
    • 0026337077 scopus 로고
    • The coagulation cascade: Initiation, maintenance, and regulation
    • E.W. Davie, K. Fujikawa, and W. Kisiel The coagulation cascade: initiation, maintenance, and regulation Biochemistry 30 43 1991 10363 10370
    • (1991) Biochemistry , vol.30 , Issue.43 , pp. 10363-10370
    • Davie, E.W.1    Fujikawa, K.2    Kisiel, W.3
  • 23
    • 0348048783 scopus 로고    scopus 로고
    • Anticoagulant peptides from Ancylostoma caninum are immunologically distinct and localize to separate structures within the adult hookworm
    • DOI 10.1016/j.molbiopara.2003.10.015
    • J. Mieszczanek, L.M. Harrison, G.P. Vlasuk, and M. Cappello Anticoagulant peptides from Ancylostoma caninum are immunologically distinct and localize to separate structures within the adult hookworm Mol Biochem Parasitol 133 2 2004 319 323 (Pubitemid 38032880)
    • (2004) Molecular and Biochemical Parasitology , vol.133 , Issue.2 , pp. 319-323
    • Mieszczanek, J.1    Harrison, L.M.2    Vlasuk, G.P.3    Cappello, M.4
  • 26
    • 0037242769 scopus 로고    scopus 로고
    • Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: Gene transcription pattern, ligand binding properties and structural characterisation
    • DOI 10.1016/S0166-6851(02)00253-0, PII S0166685102002530
    • S. Basavaraju, B. Zhan, M.W. Kennedy, Y. Liu, J. Hawdon, and P.J. Hotez Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation Mol Biochem Parasitol 126 2003 63 71 (Pubitemid 36124012)
    • (2003) Molecular and Biochemical Parasitology , vol.126 , Issue.1 , pp. 63-71
    • Basavaraju, S.1    Zhan, B.2    Kennedy, M.W.3    Liu, Y.4    Hawdon, J.5    Hotez, P.J.6
  • 29
    • 0037046107 scopus 로고    scopus 로고
    • A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases
    • PII S0166685101004534
    • B. Zhan, J.P. Hotez, Y. Wang, and M.J. Hawdon A. developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of protease Mol Biochem Parasitol 120 2002 291 296 (Pubitemid 34233793)
    • (2002) Molecular and Biochemical Parasitology , vol.120 , Issue.2 , pp. 291-296
    • Zhan, B.1    Hotez, P.J.2    Wang, Y.3    Hawdon, J.M.4
  • 30
    • 0028896718 scopus 로고
    • Cloning and characterization of a cDNA encoding the catalytic subunit of a cAMP-dependent protein kinase from Ancylostoma caninum third-stage infective larvae
    • J.M. Hawdon, B.F. Jones, and P.J. Hotez Cloning and characterization of a cDNA encoding the catalytic subunit of a cAMP-dependent protein kinase from Ancylostoma caninum third-stage infective larvae Mol Biochem Parasitol 69 1995 127 130
    • (1995) Mol Biochem Parasitol , vol.69 , pp. 127-130
    • Hawdon, J.M.1    Jones, B.F.2    Hotez, P.J.3
  • 32
    • 0036718532 scopus 로고    scopus 로고
    • Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity
    • A.L. Williamson, P.J. Brindley, and G. Abbenante Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity FASEB J 16 11 2002 1458 1460
    • (2002) FASEB J , vol.16 , Issue.11 , pp. 1458-1460
    • Williamson, A.L.1    Brindley, P.J.2    Abbenante, G.3
  • 33
    • 0028773904 scopus 로고
    • High-resolution structure of Ascaris trypsin inhibitor in solution: Direct evidence for a pH-induced conformational transition in the reactive site
    • B.L. Grasberger, G.M. Clore, and A.M. Gronenborn High-resolution structure of Ascaris trypsin inhibitor in solution: direct evidence for a pH-induced conformational transition in the reactive site Structure 2 1994 669 678
    • (1994) Structure , vol.2 , pp. 669-678
    • Grasberger, B.L.1    Clore, G.M.2    Gronenborn, A.M.3
  • 34
    • 0028773905 scopus 로고
    • The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase
    • K. Huang, N.C. Strynadka, V.D. Bernard, R.J. Peanasky, and M.N. James The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase Structure 2 1994 679 689
    • (1994) Structure , vol.2 , pp. 679-689
    • Huang, K.1    Strynadka, N.C.2    Bernard, V.D.3    Peanasky, R.J.4    James, M.N.5
  • 35
    • 0027196767 scopus 로고
    • The serine protease inhibitor family from Ascaris suum: Chemical determination of the five disulfide bridges
    • DOI 10.1006/abbi.1993.1297
    • V.D. Bernard, and R.J. Peanasky The serine protease inhibitor family from Ascaris suum: chemical determination of the five disulfide bridges Arch Biochem Biophys 303 2 1993 367 376 (Pubitemid 23199835)
    • (1993) Archives of Biochemistry and Biophysics , vol.303 , Issue.2 , pp. 367-376
    • Bernard, V.D.1    Peanasky, R.J.2
  • 36
    • 77950278221 scopus 로고    scopus 로고
    • Molecular cloning, biochemical characterization, and vaccine potential of the heme-binding glutathione transferases from the human hookworm Necator americanus
    • B. Zhan, S. Perally, and P.M. Brophy Molecular cloning, biochemical characterization, and vaccine potential of the heme-binding glutathione transferases from the human hookworm Necator americanus Infect Immun 78 4 2010 1552 1563
    • (2010) Infect Immun , vol.78 , Issue.4 , pp. 1552-1563
    • Zhan, B.1    Perally, S.2    Brophy, P.M.3
  • 37
    • 0346134097 scopus 로고    scopus 로고
    • Molecular pathogenesis of hookworm anemia: Prospects for a disease based vaccine
    • M. Cappello, R.D. Bungiro, and C.R. Chadderdon Molecular pathogenesis of hookworm anemia: prospects for a disease based vaccine J Parasitol 89 2003 S158 S164
    • (2003) J Parasitol , vol.89
    • Cappello, M.1    Bungiro, R.D.2    Chadderdon, C.R.3
  • 38
    • 33846809115 scopus 로고    scopus 로고
    • Saposin-like proteins from the intestine of the blood-feeding hookworm, Ancylostoma caninum
    • DOI 10.1017/S003118200600148X, PII S003118200600148X
    • T.A. Don, Y. Oksov, S. Lustigman, and A. Loukas Saposin-like proteins from the intestine of the blood-feeding hookworm, Ancylostoma caninum Parasitology 134 Pt 3 2007 427 436 (Pubitemid 46208025)
    • (2007) Parasitology , vol.134 , Issue.3 , pp. 427-436
    • Don, T.A.1    Oksov, Y.2    Lustigman, S.3    Loukas, A.4
  • 40
    • 77958082295 scopus 로고    scopus 로고
    • Developing vaccines to combat hookworm infection and intestinal schistosomiasis
    • P.J. Hotez, J.M. Bethony, D. Diemert, M. Pearson, and A. Loukas Developing vaccines to combat hookworm infection and intestinal schistosomiasis Nat Rev Microbiol 8 11 2010 814 826
    • (2010) Nat Rev Microbiol , vol.8 , Issue.11 , pp. 814-826
    • Hotez, P.J.1    Bethony, J.M.2    Diemert, D.3    Pearson, M.4    Loukas, A.5


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