메뉴 건너뛰기




Volumn 71, Issue 1, 2012, Pages 117-125

Role of cancer stem cells in spine tumors: Review of current literature

Author keywords

Cancer; Chordoma; Spine; Stem cells; Surgery

Indexed keywords

BORTEZOMIB; CISPLATIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; DEXAMETHASONE; DOXORUBICIN; IFOSFAMIDE; LENALIDOMIDE; METHOTREXATE; VINCRISTINE;

EID: 84862866416     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/NEU.0b013e3182532e71     Document Type: Review
Times cited : (11)

References (117)
  • 1
    • 33947433676 scopus 로고    scopus 로고
    • Cancer stem cells: At the headwaters of tumor development
    • DOI 10.1146/annurev.pathol.2.010506.091847, Annual Review of Pathology: Mechanisms of Disease
    • Ward RJ, Dirks PB. Cancer stem cells: at the headwaters of tumor development. Annu Rev Pathol. 2007;2:175-189. (Pubitemid 46448063)
    • (2007) Annual Review of Pathology , vol.2 , pp. 175-189
    • Ward, R.J.1    Dirks, P.B.2
  • 2
    • 75649109727 scopus 로고    scopus 로고
    • Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes
    • Jacques TS, Swales A, Brzozowski MJ, et al. Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes. EMBO J. 2010;29(1):222-235.
    • (2010) EMBO J , vol.29 , Issue.1 , pp. 222-235
    • Jacques, T.S.1    Swales, A.2    Brzozowski, M.J.3
  • 3
    • 0035425048 scopus 로고    scopus 로고
    • PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas from and oligoastrocytomas neural progenitors and astrocytes in vivo
    • DOI 10.1101/gad.903001
    • Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev. 2001;15(15):1913-1925. (Pubitemid 32738621)
    • (2001) Genes and Development , vol.15 , Issue.15 , pp. 1913-1925
    • Dai, C.1    Celestino, J.C.2    Okada, Y.3    Louis, D.N.4    Fuller, G.N.5    Holland, E.C.6
  • 6
    • 65349115320 scopus 로고    scopus 로고
    • SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
    • Son MJ, Woolard K, Nam DH, Lee J, Fine HA. SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell. 2009;4(5):440-452.
    • (2009) Cell Stem Cell , vol.4 , Issue.5 , pp. 440-452
    • Son, M.J.1    Woolard, K.2    Nam, D.H.3    Lee, J.4    Fine, H.A.5
  • 7
    • 77956245743 scopus 로고    scopus 로고
    • Integrin alpha 6 regulates glioblastoma stem cells
    • Lathia JD, Gallagher J, Heddleston JM, et al. Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell. 2010;6(5):421-432.
    • (2010) Cell Stem Cell , vol.6 , Issue.5 , pp. 421-432
    • Lathia, J.D.1    Gallagher, J.2    Heddleston, J.M.3
  • 8
    • 0035877989 scopus 로고    scopus 로고
    • Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34(1)CD38(-) progenitor cells from patients with acute myeloid leukemia
    • Feuring-Buske M, Hogge DE. Hoechst 33342 efflux identifies a subpopulation of cytogenetically normal CD34(1)CD38(-) progenitor cells from patients with acute myeloid leukemia. Blood. 2001;97(12):3882-3889.
    • (2001) Blood , vol.97 , Issue.12 , pp. 3882-3889
    • Feuring-Buske, M.1    Hogge, D.E.2
  • 10
    • 62549152644 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer
    • Jiang F, Qiu Q, Khanna A, et al. Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer. Mol Cancer Res. 2009;7(3):330-338.
    • (2009) Mol Cancer Res , vol.7 , Issue.3 , pp. 330-338
    • Jiang, F.1    Qiu, Q.2    Khanna, A.3
  • 11
    • 70350247558 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer
    • Carpentino JE, Hynes MJ, Appelman HD, et al. Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer. Cancer Res. 2009;69(20):8208-8215.
    • (2009) Cancer Res , vol.69 , Issue.20 , pp. 8208-8215
    • Carpentino, J.E.1    Hynes, M.J.2    Appelman, H.D.3
  • 12
    • 33644825465 scopus 로고    scopus 로고
    • Stem-like cells in bone sarcomas: Implications for tumorigenesis
    • Gibbs CP, Kukekov VG, Reith JD, et al. Stem-like cells in bone sarcomas: implications for tumorigenesis. Neoplasia. 2005;7(11):967-976.
    • (2005) Neoplasia , vol.7 , Issue.11 , pp. 967-976
    • Gibbs, C.P.1    Kukekov, V.G.2    Reith, J.D.3
  • 13
    • 78649580167 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99-1 cells based on high aldehyde dehydrogenase activity
    • Wang L, Park P, Zhang H, La Marca F, Lin CY. Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99-1 cells based on high aldehyde dehydrogenase activity. Int J Cancer. 2011;128(2):294-303.
    • (2011) Int J Cancer , vol.128 , Issue.2 , pp. 294-303
    • Wang, L.1    Park, P.2    Zhang, H.3    La Marca, F.4    Lin, C.Y.5
  • 14
    • 62449230721 scopus 로고    scopus 로고
    • Identification of cancer stem cells in Ewing's sarcoma
    • Suva ML, Riggi N, Stehle JC, et al. Identification of cancer stem cells in Ewing's sarcoma. Cancer Res. 2009;69(5):1776-1781.
    • (2009) Cancer Res , vol.69 , Issue.5 , pp. 1776-1781
    • Suva, M.L.1    Riggi, N.2    Stehle, J.C.3
  • 15
    • 33845671339 scopus 로고    scopus 로고
    • Analysis of gene expression and chemoresistance of CD1331 cancer stem cells in glioblastoma
    • Liu G, Yuan X, Zeng Z, et al. Analysis of gene expression and chemoresistance of CD1331 cancer stem cells in glioblastoma. Mol Cancer. 2006;5(5):67.
    • (2006) Mol Cancer , vol.5 , Issue.5 , pp. 67
    • Liu, G.1    Yuan, X.2    Zeng, Z.3
  • 16
    • 68249157942 scopus 로고    scopus 로고
    • Glioblastoma stem cells resistant to temozolomide-induced autophagy
    • Fu J, Liu ZG, Liu XM, et al. Glioblastoma stem cells resistant to temozolomide-induced autophagy. Chin Med J (Engl). 2009;122(11):1255-1259.
    • (2009) Chin Med J (Engl) , vol.122 , Issue.11 , pp. 1255-1259
    • Fu, J.1    Liu, Z.G.2    Liu, X.M.3
  • 17
    • 60849117508 scopus 로고    scopus 로고
    • PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
    • Bleau AM, Hambardzumyan D, Ozawa T, et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell. 2009;4(3):226-235.
    • (2009) Cell Stem Cell , vol.4 , Issue.3 , pp. 226-235
    • Bleau, A.M.1    Hambardzumyan, D.2    Ozawa, T.3
  • 18
    • 48949119473 scopus 로고    scopus 로고
    • Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
    • Fillmore CM, Kuperwasser C. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res. 2008;10(2):R25.
    • (2008) Breast Cancer Res , vol.10 , Issue.2
    • Fillmore, C.M.1    Kuperwasser, C.2
  • 19
    • 44049100934 scopus 로고    scopus 로고
    • Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
    • Li X, Lewis MT, Huang J, et al. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst. 2008;100(9):672-679.
    • (2008) J Natl Cancer Inst , vol.100 , Issue.9 , pp. 672-679
    • Li, X.1    Lewis, M.T.2    Huang, J.3
  • 20
    • 69549131213 scopus 로고    scopus 로고
    • Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
    • Creighton CJ, Li X, Landis M, et al. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A. 2009;106(33):13820-13825.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.33 , pp. 13820-13825
    • Creighton, C.J.1    Li, X.2    Landis, M.3
  • 21
    • 70349479538 scopus 로고    scopus 로고
    • Highly tumorigenic lung cancer CD1331 cells display stem-like features and are spared by cisplatin treatment
    • Bertolini G, Roz L, Perego P, et al. Highly tumorigenic lung cancer CD1331 cells display stem-like features and are spared by cisplatin treatment. Proc Natl Acad Sci U S A. 2009;106(38):16281-16286.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.38 , pp. 16281-16286
    • Bertolini, G.1    Roz, L.2    Perego, P.3
  • 22
    • 40749150740 scopus 로고    scopus 로고
    • + HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
    • DOI 10.1038/sj.onc.1210811, PII 1210811
    • Ma S, Lee TK, Zheng BJ, Chan KW, Guan XY. CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway. Oncogene. 2008;27(12):1749-1758. (Pubitemid 351380265)
    • (2008) Oncogene , vol.27 , Issue.12 , pp. 1749-1758
    • Ma, S.1    Lee, T.K.2    Zheng, B.-J.3    Chan, K.W.4    Guan, X.-Y.5
  • 23
    • 76749139548 scopus 로고    scopus 로고
    • Do stem-like cells play a role in drug resistance of sarcomas?
    • Honoki K. Do stem-like cells play a role in drug resistance of sarcomas?. Expert Rev Anticancer Ther. 2010;10(2):261-270.
    • (2010) Expert Rev Anticancer Ther , vol.10 , Issue.2 , pp. 261-270
    • Honoki, K.1
  • 24
    • 35148888629 scopus 로고    scopus 로고
    • Cancer stem cells in radiation resistance
    • DOI 10.1158/0008-5472.CAN-07-0895
    • Rich JN. Cancer stem cells in radiation resistance. Cancer Res. 2007;67(19): 8980-8984. (Pubitemid 47535877)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 8980-8984
    • Rich, J.N.1
  • 28
    • 33747874155 scopus 로고    scopus 로고
    • Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
    • DOI 10.1158/0008-5472.CAN-06-0858
    • Fan X, Matsui W, Khaki L, et al. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res. 2006;66 (15):7445-7452. (Pubitemid 44289197)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7445-7452
    • Fan, X.1    Matsui, W.2    Khaki, L.3    Stearns, D.4    Chun, J.5    Li, Y.-M.6    Eberhart, C.G.7
  • 29
    • 33846237601 scopus 로고    scopus 로고
    • HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity
    • DOI 10.1016/j.cub.2006.11.033, PII S0960982206025140
    • Clement V, Sanchez P, de Tribolet N, Radovanovic I, Ruiz i Altaba A. HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity. Curr Biol. 2007;17(2):165-172. (Pubitemid 46107823)
    • (2007) Current Biology , vol.17 , Issue.2 , pp. 165-172
    • Clement, V.1    Sanchez, P.2    De Tribolet, N.3    Radovanovic, I.4    Ruiz, I.A.A.5
  • 31
    • 0036681993 scopus 로고    scopus 로고
    • The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner
    • Chakravarti A, Chakladar A, Delaney MA, Latham DE, Loeffler JS. The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner. Cancer Res. 2002;62(15):4307-4315. (Pubitemid 34827287)
    • (2002) Cancer Research , vol.62 , Issue.15 , pp. 4307-4315
    • Chakravarti, A.1    Chakladar, A.2    Delaney, M.A.3    Latham, D.E.4    Loeffler, J.S.5
  • 34
    • 25444495269 scopus 로고    scopus 로고
    • Migrating cancer stem cells - An integrated concept of malignant tumour progression
    • DOI 10.1038/nrc1694, PII N1694
    • Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat Rev Cancer. 2005;5(9):744-749. (Pubitemid 41486367)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.9 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 35
    • 33750306612 scopus 로고    scopus 로고
    • Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
    • DOI 10.1158/1078-0432.CCR-06-0169
    • Balic M, Lin H, Young L, et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin Cancer Res. 2006;12(19):5615-5621. (Pubitemid 44629587)
    • (2006) Clinical Cancer Research , vol.12 , Issue.19 , pp. 5615-5621
    • Balic, M.1    Lin, H.2    Young, L.3    Hawes, D.4    Giuliano, A.5    McNamara, G.6    Datar, R.H.7    Cote, R.J.8
  • 36
    • 33645026803 scopus 로고    scopus 로고
    • Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
    • Patrawala L, Calhoun T, Schneider-Broussard R, et al. Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene. 2006;25(12):1696-1708.
    • (2006) Oncogene , vol.25 , Issue.12 , pp. 1696-1708
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3
  • 37
    • 34548175512 scopus 로고    scopus 로고
    • Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
    • DOI 10.1111/j.1349-7006.2007.00550.x
    • Moustakas A, Heldin CH. Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression. Cancer Sci. 2007;98 (10):1512-1520. (Pubitemid 47308444)
    • (2007) Cancer Science , vol.98 , Issue.10 , pp. 1512-1520
    • Moustakas, A.1    Heldin, C.-H.2
  • 38
    • 75449106680 scopus 로고    scopus 로고
    • Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients
    • Aktas B, TewesM, Fehm T, Hauch S, Kimmig R, Kasimir-Bauer S. Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients. Breast Cancer Res. 2009;11(4):R46.
    • (2009) Breast Cancer Res , vol.11 , Issue.4
    • Aktas, B.1    Tewes, M.2    Fehm, T.3    Hauch, S.4    Kimmig, R.5    Kasimir-Bauer, S.6
  • 39
    • 12944288172 scopus 로고    scopus 로고
    • Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis
    • Abraham BK, Fritz P, McClellan M, Hauptvogel P, Athelogou M, Brauch H. Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. Clin Cancer Res. 2005;11 (3):1154-1159.
    • (2005) Clin Cancer Res , vol.11 , Issue.3 , pp. 1154-1159
    • Abraham, B.K.1    Fritz, P.2    McClellan, M.3    Hauptvogel, P.4    Athelogou, M.5    Brauch, H.6
  • 40
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS One. 2008;3(8):e2888.
    • (2008) PLoS One , vol.3 , Issue.8
    • Morel, A.P.1    Lievre, M.2    Thomas, C.3    Hinkal, G.4    Ansieau, S.5    Puisieux, A.6
  • 41
    • 25144488085 scopus 로고    scopus 로고
    • Wnt, hedgehog and snail: Sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis
    • Zhou BP, Hung MC. Wnt, hedgehog and snail: sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis. Cell Cycle. 2005;4(6): 772-776. (Pubitemid 41353827)
    • (2005) Cell Cycle , vol.4 , Issue.6 , pp. 772-776
    • Zhou, B.P.1    Hung, M.-C.2
  • 42
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • DOI 10.1038/nrm1835, PII NRM1835
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol. 2006;7(2):131-142. (Pubitemid 43278296)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 43
    • 34548455927 scopus 로고    scopus 로고
    • Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer
    • DOI 10.1016/j.stem.2007.06.002, PII S1934590907000665
    • Hermann PC, Huber SL, Herrler T, et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell. 2007;1(3):313-323. (Pubitemid 47355323)
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 44
    • 34848851037 scopus 로고    scopus 로고
    • Interplay of distinct growth factors during epithelial-mesenchymal transition of cancer progenitor cells and molecular targeting as novel cancer therapies
    • DOI 10.1093/annonc/mdm070
    • Mimeault M, Batra SK. Interplay of distinct growth factors during epithelial mesenchymal transition of cancer progenitor cells and molecular targeting as novel cancer therapies. Ann Oncol. 2007;18(10):1605-1619. (Pubitemid 47506246)
    • (2007) Annals of Oncology , vol.18 , Issue.10 , pp. 1605-1619
    • Mimeault, M.1    Batra, S.K.2
  • 45
    • 42649137241 scopus 로고    scopus 로고
    • Mechanisms of disease: Epithelial-mesenchymal transition - Does cellular plasticity fuel neoplastic progression?
    • DOI 10.1038/ncponc1089, PII NCPONC1089
    • Turley EA, Veiseh M, Radisky DC, Bissell MJ.Mechanisms of disease: epithelial-mesenchymal transition - does cellular plasticity fuel neoplastic progression?. Nat Clin Pract Oncol. 2008;5(5):280-290. (Pubitemid 351594144)
    • (2008) Nature Clinical Practice Oncology , vol.5 , Issue.5 , pp. 280-290
    • Turley, E.A.1    Veiseh, M.2    Radisky, D.C.3    Bissell, M.J.4
  • 46
    • 44449149171 scopus 로고    scopus 로고
    • Dynamic control of TGF-beta signaling and its links to the cytoskeleton
    • Moustakas A, Heldin CH. Dynamic control of TGF-beta signaling and its links to the cytoskeleton. FEBS Lett. 2008;582(14):2051-2065.
    • (2008) FEBS Lett , vol.582 , Issue.14 , pp. 2051-2065
    • Moustakas, A.1    Heldin, C.H.2
  • 47
    • 70349859809 scopus 로고    scopus 로고
    • Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells
    • Kurrey NK, Jalgaonkar SP, Joglekar AV, et al. Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells. Stem Cells. 2009;27 (9):2059-2068.
    • (2009) Stem Cells , vol.27 , Issue.9 , pp. 2059-2068
    • Kurrey, N.K.1    Jalgaonkar, S.P.2    Joglekar, A.V.3
  • 48
    • 67650496215 scopus 로고    scopus 로고
    • A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer
    • DiMeo TA, Anderson K, Phadke P, et al. A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer. Cancer Res. 2009;69(13):5364-5373.
    • (2009) Cancer Res , vol.69 , Issue.13 , pp. 5364-5373
    • DiMeo, T.A.1    Anderson, K.2    Phadke, P.3
  • 49
    • 38049043823 scopus 로고    scopus 로고
    • The basal-like breast carcinoma phenotype is regulated by SLUG gene expression
    • Storci G, Sansone P, Trere D, et al. The basal-like breast carcinoma phenotype is regulated by SLUG gene expression. J Pathol. 2008;214(1):25-37.
    • (2008) J Pathol , vol.214 , Issue.1 , pp. 25-37
    • Storci, G.1    Sansone, P.2    Trere, D.3
  • 50
    • 53949090765 scopus 로고    scopus 로고
    • NF-kappaB signaling pathway and its therapeutic implications in human diseases
    • Sarkar FH, Li Y,Wang Z, KongD. NF-kappaB signaling pathway and its therapeutic implications in human diseases. Int Rev Immunol. 2008;27(5):293-319.
    • (2008) Int Rev Immunol , vol.27 , Issue.5 , pp. 293-319
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4
  • 51
    • 54449085718 scopus 로고    scopus 로고
    • Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers
    • Dumont N, Wilson MB, Crawford YG, Reynolds PA, Sigaroudinia M, Tlsty TD. Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers. Proc Natl Acad Sci U S A. 2008;105(39):14867-14872.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.39 , pp. 14867-14872
    • Dumont, N.1    Wilson, M.B.2    Crawford, Y.G.3    Reynolds, P.A.4    Sigaroudinia, M.5    Tlsty, T.D.6
  • 52
    • 54249151684 scopus 로고    scopus 로고
    • Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction
    • Das B, Tsuchida R, Malkin D, Koren G, Baruchel S, Yeger H. Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction. Stem Cells. 2008;26(7):1818-1830.
    • (2008) Stem Cells , vol.26 , Issue.7 , pp. 1818-1830
    • Das, B.1    Tsuchida, R.2    Malkin, D.3    Koren, G.4    Baruchel, S.5    Yeger, H.6
  • 55
    • 36349006961 scopus 로고    scopus 로고
    • Development and characterization of gemcitabine-resistant pancreatic tumor cells
    • DOI 10.1245/s10434-007-9583-5
    • Shah AN, Summy JM, Zhang J, Park SI, Parikh NU, Gallick GE. Development and characterization of gemcitabine-resistant pancreatic tumor cells. Ann Surg Oncol. 2007;14(12):3629-3637. (Pubitemid 350160137)
    • (2007) Annals of Surgical Oncology , vol.14 , Issue.12 , pp. 3629-3637
    • Shah, A.N.1    Summy, J.M.2    Zhang, J.3    Park, S.I.4    Parikh, N.U.5    Gallick, G.E.6
  • 56
    • 36348941863 scopus 로고    scopus 로고
    • Bone metastasis: Pathogenesis and therapeutic implications
    • DOI 10.1007/s10585-007-9112-8
    • Clezardin P, Teti A. Bone metastasis: pathogenesis and therapeutic implications. Clin Exp Metastasis. 2007;24(8):599-608. (Pubitemid 50003596)
    • (2007) Clinical and Experimental Metastasis , vol.24 , Issue.8 , pp. 599-608
    • Clezardin, P.1    Teti, A.2
  • 57
    • 52049118079 scopus 로고    scopus 로고
    • The role of metastasis suppressor genes in metastatic dormancy
    • Horak CE, Lee JH, Marshall JC, Shreeve SM, Steeg PS. The role of metastasis suppressor genes in metastatic dormancy. APMIS. 2008;116(7-8):586- 601.
    • (2008) APMIS , vol.116 , Issue.7-8 , pp. 586-601
    • Horak, C.E.1    Lee, J.H.2    Marshall, J.C.3    Shreeve, S.M.4    Steeg, P.S.5
  • 58
    • 44649107292 scopus 로고    scopus 로고
    • Mechanisms of Disease: Cancer stem cells-targeting the evil twin
    • DOI 10.1038/ncponc1110, PII NCPONC1110
    • Trumpp A, Wiestler OD. Mechanisms of disease: cancer stem cells - targeting the evil twin. Nat Clin Pract Oncol. 2008;5(6):337-347. (Pubitemid 351780950)
    • (2008) Nature Clinical Practice Oncology , vol.5 , Issue.6 , pp. 337-347
    • Trumpp, A.1    Wiestler, O.D.2
  • 59
    • 43549083683 scopus 로고    scopus 로고
    • Bone marrow micrometastasis in breast cancer: Review of detection methods, prognostic impact and biological issues
    • DOI 10.1136/jcp.2007.046649
    • Vincent-Salomon A, Bidard FC, Pierga JY. Bone marrow micrometastasis in breast cancer: review of detection methods, prognostic impact and biological issues. J Clin Pathol. 2008;61(5):570-576. (Pubitemid 351678207)
    • (2008) Journal of Clinical Pathology , vol.61 , Issue.5 , pp. 570-576
    • Vincent-Salomon, A.1    Bidard, F.C.2    Pierga, J.Y.3
  • 60
    • 33645553503 scopus 로고    scopus 로고
    • Osteosarcoma: Anatomic and histologic variants
    • Klein MJ, Siegal GP. Osteosarcoma: anatomic and histologic variants. Am J Clin Pathol. 2006;125(4):555-581.
    • (2006) Am J Clin Pathol , vol.125 , Issue.4 , pp. 555-581
    • Klein, M.J.1    Siegal, G.P.2
  • 61
    • 52449087795 scopus 로고    scopus 로고
    • Surgical management of primary and metastatic sarcoma of the mobile spine
    • Rao G, Suki D, Chakrabarti I, et al. Surgical management of primary and metastatic sarcoma of the mobile spine. J Neurosurg Spine. 2008;9(2):120-128.
    • (2008) J Neurosurg Spine , vol.9 , Issue.2 , pp. 120-128
    • Rao, G.1    Suki, D.2    Chakrabarti, I.3
  • 62
    • 67649424217 scopus 로고    scopus 로고
    • Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines
    • Fujii H, Honoki K, Tsujiuchi T, Kido A, Yoshitani K, Takakura Y. Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines. Int J Oncol. 2009;34(5):1381-1386.
    • (2009) Int J Oncol , vol.34 , Issue.5 , pp. 1381-1386
    • Fujii, H.1    Honoki, K.2    Tsujiuchi, T.3    Kido, A.4    Yoshitani, K.5    Takakura, Y.6
  • 63
    • 66149092673 scopus 로고    scopus 로고
    • Characterization of stem cell attributes in human osteosarcoma cell lines
    • Wang L, Park P, Lin CY. Characterization of stem cell attributes in human osteosarcoma cell lines. Cancer Biol Ther. 2009;8(6):543-552.
    • (2009) Cancer Biol Ther , vol.8 , Issue.6 , pp. 543-552
    • Wang, L.1    Park, P.2    Lin, C.Y.3
  • 64
    • 67651005780 scopus 로고    scopus 로고
    • Expression of an exogenous human Oct-4 promoter identifies tumor-initiating cells in osteosarcoma
    • Levings PP, McGarry SV, Currie TP, et al. Expression of an exogenous human Oct-4 promoter identifies tumor-initiating cells in osteosarcoma. Cancer Res. 2009;69(14):5648-5655.
    • (2009) Cancer Res , vol.69 , Issue.14 , pp. 5648-5655
    • Levings, P.P.1    McGarry, S.V.2    Currie, T.P.3
  • 66
    • 34447324657 scopus 로고    scopus 로고
    • The Biology of Ewing sarcoma
    • DOI 10.1016/j.canlet.2006.12.009, PII S0304383506006811
    • Riggi N, Stamenkovic I. The biology of Ewing sarcoma. Cancer Lett. 2007;254 (1):1-10. (Pubitemid 47058800)
    • (2007) Cancer Letters , vol.254 , Issue.1 , pp. 1-10
    • Riggi, N.1    Stamenkovic, I.2
  • 68
    • 25444507396 scopus 로고    scopus 로고
    • Expression of the EWS/FLI-1 oncogene in murine primary bone-derived cells results in EWS/FLI-1-dependent, Ewing sarcoma-like tumors
    • DOI 10.1158/0008-5472.CAN-05-1704
    • Castillero-Trejo Y, Eliazer S, Xiang L, Richardson JA, Ilaria RL Jr. Expression of the EWS/FLI-1 oncogene in murine primary bone-derived cells. Results in EWS/FLI-1-dependent, Ewing sarcoma-like tumors. Cancer Res. 2005;65(19): 8698-8705. (Pubitemid 41377357)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8698-8705
    • Castillero-Trejo, Y.1    Eliazer, S.2    Xiang, L.3    Richardson, J.A.4    Ilaria Jr., R.L.5
  • 69
    • 77951785861 scopus 로고    scopus 로고
    • EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells
    • Riggi N, Suva ML, De Vito C, et al. EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells. Genes Dev. 2010;24(9):916-932.
    • (2010) Genes Dev , vol.24 , Issue.9 , pp. 916-932
    • Riggi, N.1    Suva, M.L.2    De Vito, C.3
  • 70
    • 72949097627 scopus 로고    scopus 로고
    • Detection and characterization of side population in Ewing's sarcoma SK-ES-1 cells in vitro
    • Yang M, Zhang R, Yan M, Ye Z, Liang W, Luo Z. Detection and characterization of side population in Ewing's sarcoma SK-ES-1 cells in vitro. Biochem Biophys Res Commun. 2010;391(1):1062-1066.
    • (2010) Biochem Biophys Res Commun , vol.391 , Issue.1 , pp. 1062-1066
    • Yang, M.1    Zhang, R.2    Yan, M.3    Ye, Z.4    Liang, W.5    Luo, Z.6
  • 71
    • 36849001255 scopus 로고    scopus 로고
    • Identification of side population cells (stem-like cell population) in pediatric solid tumor cell lines
    • DOI 10.1016/j.jpedsurg.2007.08.026, PII S0022346807005891
    • Komuro H, Saihara R, Shinya M, et al. Identification of side population cells (stem-like cell population) in pediatric solid tumor cell lines. J Pediatr Surg. 2007; 42(12):2040-2045. (Pubitemid 350235504)
    • (2007) Journal of Pediatric Surgery , vol.42 , Issue.12 , pp. 2040-2045
    • Komuro, H.1    Saihara, R.2    Shinya, M.3    Takita, J.4    Kaneko, S.5    Kaneko, M.6    Hayashi, Y.7
  • 72
    • 77952893906 scopus 로고    scopus 로고
    • CD133 expression in chemo-resistant Ewing sarcoma cells
    • Jiang X, Gwye Y, Russell D, et al. CD133 expression in chemo-resistant Ewing sarcoma cells. BMC Cancer. 2010;10(12):116.
    • (2010) BMC Cancer , vol.10 , Issue.12 , pp. 116
    • Jiang, X.1    Gwye, Y.2    Russell, D.3
  • 75
    • 33846063691 scopus 로고    scopus 로고
    • Margin-free spondylectomy for extended malignant spine tumors: Surgical technique and outcome of 13 cases
    • Hasegawa K, Homma T, Hirano T, et al. Margin-free spondylectomy for extended malignant spine tumors: surgical technique and outcome of 13 cases. Spine (Phila Pa 1976). 2007;32(1):142-148.
    • (2007) Spine (Phila Pa 1976) , vol.32 , Issue.1 , pp. 142-148
    • Hasegawa, K.1    Homma, T.2    Hirano, T.3
  • 76
    • 0031059889 scopus 로고    scopus 로고
    • Total en bloc spondylectomy. A new surgical technique for primary malignant vertebral tumors
    • Tomita K, Kawahara N, Baba H, Tsuchiya H, Fujita T, Toribatake Y. Total en bloc spondylectomy. A new surgical technique for primary malignant vertebral tumors. Spine (Phila Pa 1976). 1997;22(3):324-333.
    • (1997) Spine (Phila Pa 1976) , vol.22 , Issue.3 , pp. 324-333
    • Tomita, K.1    Kawahara, N.2    Baba, H.3    Tsuchiya, H.4    Fujita, T.5    Toribatake, Y.6
  • 78
    • 0028343784 scopus 로고
    • Alternative splice form of type II procollagen mRNA (IIA) is predominant in skeletal precursors and non-cartilaginous tissues during early mouse development
    • Sandell LJ, Nalin AM, Reife RA. Alternative splice form of type II procollagen mRNA (IIA) is predominant in skeletal precursors and non-cartilaginous tissues during early mouse development. Dev Dyn. 1994;199(2):129-140. (Pubitemid 24071349)
    • (1994) Developmental Dynamics , vol.199 , Issue.2 , pp. 129-140
    • Sandell, L.J.1    Nalin, A.M.2    Reife, R.A.3
  • 79
    • 0016431708 scopus 로고
    • Multiple myeloma: Review of 869 cases
    • Kyle RA. Multiple myeloma: review of 869 cases. Mayo Clin Proc. 1975;50(1): 29-40.
    • (1975) Mayo Clin Proc , vol.50 , Issue.1 , pp. 29-40
    • Kyle, R.A.1
  • 81
    • 34250333326 scopus 로고    scopus 로고
    • The use of bisphosphonates in cancer patients
    • DOI 10.1080/02841860701233435, PII 779468969
    • Wu S, Dahut WL, Gulley JL. The use of bisphosphonates in cancer patients. Acta Oncol. 2007;46(5):581-591. (Pubitemid 46911914)
    • (2007) Acta Oncologica , vol.46 , Issue.5 , pp. 581-591
    • Wu, S.1    Dahut, W.L.2    Gulley, J.L.3
  • 82
    • 0037443533 scopus 로고    scopus 로고
    • RANK ligand and osteoprotegerin in myeloma bone disease
    • DOI 10.1182/blood-2002-09-2684
    • Sezer O, Heider U, Zavrski I, Kuhne CA, Hofbauer LC. RANK ligand and osteoprotegerin in myeloma bone disease. Blood. 2003;101(6):2094-2098. (Pubitemid 36302042)
    • (2003) Blood , vol.101 , Issue.6 , pp. 2094-2098
    • Sezer, O.1    Heider, U.2    Zavrski, I.3    Kuhne, C.A.4    Hofbauer, L.C.5
  • 84
    • 0030911847 scopus 로고    scopus 로고
    • Comparison of melphalan and prednisone with vincristine, carmustine, melphalan, cyclophosphamide, and prednisone in the treatment of multiple myeloma: Results of Eastern Cooperative Oncology Group Study E2479
    • DOI 10.1002/(SICI)1097-0142(19970415)79:8<1561::AID-CNCR18>3.0. CO;2-W
    • Oken MM, Harrington DP, Abramson N, Kyle RA, Knospe W, Glick JH. Comparison of melphalan and prednisone with vincristine, carmustine, melphalan, cyclophosphamide, and prednisone in the treatment of multiple myeloma: results of Eastern Cooperative Oncology Group Study E2479. Cancer. 1997;79(8):1561-1567. (Pubitemid 27154788)
    • (1997) Cancer , vol.79 , Issue.8 , pp. 1561-1567
    • Oken, M.M.1    Harrington, D.P.2    Abramson, N.3    Kyle, R.A.4    Knospe, W.5    Glick, J.H.6
  • 85
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma
    • Singhal S, Mehta J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med. 1999;341(21):1565-1571.
    • (1999) N Engl J Med , vol.341 , Issue.21 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 88
    • 0015008867 scopus 로고
    • Mouse myeloma tumor stem cells: A primary cell culture assay
    • Park CH, Bergsagel DE, McCulloch EA. Mouse myeloma tumor stem cells: a primary cell culture assay. J Natl Cancer Inst. 1971;46(2):411-422.
    • (1971) J Natl Cancer Inst , vol.46 , Issue.2 , pp. 411-422
    • Park, C.H.1    Bergsagel, D.E.2    McCulloch, E.A.3
  • 89
    • 0034599971 scopus 로고    scopus 로고
    • Antigen-specific B cell memory: Expression and replenishment of a novel b220(-) memory b cell compartment
    • McHeyzer-Williams LJ, Cool M, McHeyzer-Williams MG. Antigen-specific B cell memory: expression and replenishment of a novel b220(-) memory b cell compartment. J Exp Med. 2000;191(7):1149-1166.
    • (2000) J Exp Med , vol.191 , Issue.7 , pp. 1149-1166
    • McHeyzer-Williams, L.J.1    Cool, M.2    McHeyzer-Williams, M.G.3
  • 90
    • 0024989657 scopus 로고
    • Maintenance of B-cell memory by long-lived cells generated from proliferating precursors
    • Schittek B, Rajewsky K. Maintenance of B-cell memory by long-lived cells generated from proliferating precursors. Nature. 1990;346(6286):749-751.
    • (1990) Nature , vol.346 , Issue.6286 , pp. 749-751
    • Schittek, B.1    Rajewsky, K.2
  • 91
    • 0028961269 scopus 로고
    • Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro
    • Decker DJ, Linton PJ, Zaharevitz S, Biery M, Gingeras TR, Klinman NR. Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro. Immunity. 1995;2(2):195-203.
    • (1995) Immunity , vol.2 , Issue.2 , pp. 195-203
    • Decker, D.J.1    Linton, P.J.2    Zaharevitz, S.3    Biery, M.4    Gingeras, T.R.5    Klinman, N.R.6
  • 92
    • 38449117855 scopus 로고    scopus 로고
    • Silent development of memory progenitor B cells
    • Aviszus K, Zhang X, Wysocki LJ. Silent development of memory progenitor B cells. J Immunol. 2007;179(8):5181-5190.
    • (2007) J Immunol , vol.179 , Issue.8 , pp. 5181-5190
    • Aviszus, K.1    Zhang, X.2    Wysocki, L.J.3
  • 96
    • 0032905513 scopus 로고    scopus 로고
    • Sacral chordoma: 40-year experience at a major cancer center
    • discussion 79-80
    • York JE, Kaczaraj A, Abi-Said D, et al. Sacral chordoma: 40-year experience at a major cancer center. Neurosurgery. 1999;44(1):74-79; discussion 79-80.
    • (1999) Neurosurgery , vol.44 , Issue.1 , pp. 74-79
    • York, J.E.1    Kaczaraj, A.2    Abi-Said, D.3
  • 97
    • 0029905859 scopus 로고    scopus 로고
    • Chordoma: Long-term follow-up after radical photon irradiation
    • Catton C, O'Sullivan B, Bell R, et al. Chordoma: long-term follow-up after radical photon irradiation. Radiother Oncol. 1996;41(1):67-72.
    • (1996) Radiother Oncol , vol.41 , Issue.1 , pp. 67-72
    • Catton, C.1    O'Sullivan, B.2    Bell, R.3
  • 99
    • 40049084968 scopus 로고    scopus 로고
    • Giant cell tumor of the cervical spine: A series of 22 cases and outcomes
    • Junming M, Cheng Y, Dong C, et al. Giant cell tumor of the cervical spine: a series of 22 cases and outcomes. Spine (Phila Pa 1976). 2008;33(3):280-288.
    • (2008) Spine (Phila Pa 1976) , vol.33 , Issue.3 , pp. 280-288
    • Junming, M.1    Cheng, Y.2    Dong, C.3
  • 100
    • 0142169926 scopus 로고    scopus 로고
    • The Origin of the Neoplastic Stromal Cell in Giant Cell Tumor of Bone
    • DOI 10.1053/S0046-8177(03)00413-1
    • Wulling M, Delling G, Kaiser E. The origin of the neoplastic stromal cell in giant cell tumor of bone. Hum Pathol. 2003;34(10):983-993. (Pubitemid 37315249)
    • (2003) Human Pathology , vol.34 , Issue.10 , pp. 983-993
    • Wulling, M.1    Delling, G.2    Kaiser, E.3
  • 101
    • 0037634712 scopus 로고    scopus 로고
    • Giant cell tumor of bone: The role of fibroblast growth factor 3 positive mesenchymal stem cells in its pathogenesis
    • DOI 10.1159/000071273
    • Robinson D, Segal M, Nevo Z. Giant cell tumor of bone. The role of fibroblast growth factor 3 positive mesenchymal stem cells in its pathogenesis. Pathobiology. 2002-2003;70(6):333-342. (Pubitemid 36829008)
    • (2002) Pathobiology , vol.70 , Issue.6 , pp. 333-342
    • Robinson, D.1    Segal, M.2    Nevo, Z.3
  • 105
    • 69949134899 scopus 로고    scopus 로고
    • Glioblastoma formation from cell population depleted of Prominin1-expressing cells
    • Nishide K, Nakatani Y, Kiyonari H, Kondo T. Glioblastoma formation from cell population depleted of Prominin1-expressing cells. PLoS One. 2009;4(8):e6869.
    • (2009) PLoS One , vol.4 , Issue.8
    • Nishide, K.1    Nakatani, Y.2    Kiyonari, H.3    Kondo, T.4
  • 106
    • 34547113747 scopus 로고    scopus 로고
    • Tumor growth need not be driven by rare cancer stem cells
    • DOI 10.1126/science.1142596
    • Kelly PN, Dakic A, Adams JM, Nutt SL, Strasser A. Tumor growth need not be driven by rare cancer stem cells. Science. 2007;317(5836):337. (Pubitemid 47106366)
    • (2007) Science , vol.317 , Issue.5836 , pp. 337
    • Kelly, P.N.1    Dakic, A.2    Adams, J.M.3    Nutt, S.L.4    Strasser, A.5
  • 107
    • 37249044166 scopus 로고    scopus 로고
    • Comment on "Tumor growth need not be driven by rare cancer stem cells"
    • author reply 1722
    • Kennedy JA, Barabe F, Poeppl AG, Wang JC, Dick JE. Comment on "Tumor growth need not be driven by rare cancer stem cells". Science. 2007;318(5857): 1722; author reply 1722.
    • (2007) Science , vol.318 , Issue.5857 , pp. 1722
    • Kennedy, J.A.1    Barabe, F.2    Poeppl, A.G.3    Wang, J.C.4    Dick, J.E.5
  • 108
    • 56349113871 scopus 로고    scopus 로고
    • CD133 is a marker of bioenergetic stress in human glioma
    • Griguer CE, Oliva CR, Gobin E, et al. CD133 is a marker of bioenergetic stress in human glioma. PLoS One. 2008;3(11):e3655.
    • (2008) PLoS One , vol.3 , Issue.11
    • Griguer, C.E.1    Oliva, C.R.2    Gobin, E.3
  • 109
    • 80051967505 scopus 로고    scopus 로고
    • Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
    • Gupta PB, Fillmore CM, Jiang G, et al. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell. 2011;146(4):633-644.
    • (2011) Cell , vol.146 , Issue.4 , pp. 633-644
    • Gupta, P.B.1    Fillmore, C.M.2    Jiang, G.3
  • 111
    • 79952323440 scopus 로고    scopus 로고
    • BMP-2 inhibits the tumorigenicity of cancer stem cells in human osteosarcoma OS99-1 cell line
    • Wang L, Park P, Zhang H, et al. BMP-2 inhibits the tumorigenicity of cancer stem cells in human osteosarcoma OS99-1 cell line. Cancer Biol Ther. 2011;11 (5):457-463.
    • (2011) Cancer Biol Ther , vol.11 , Issue.5 , pp. 457-463
    • Wang, L.1    Park, P.2    Zhang, H.3
  • 112
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • Gupta PB, Onder TT, Jiang G, et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell. 2009;138(4):645-659.
    • (2009) Cell , vol.138 , Issue.4 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3
  • 113
    • 77953663505 scopus 로고    scopus 로고
    • Antibodies targeting cancer stem cells: A new paradigm in immunotherapy?
    • Deonarain MP, Kousparou CA, Epenetos AA. Antibodies targeting cancer stem cells: a new paradigm in immunotherapy?. MAbs. 2009;1(1):12-25.
    • (2009) MAbs , vol.1 , Issue.1 , pp. 12-25
    • Deonarain, M.P.1    Kousparou, C.A.2    Epenetos, A.A.3
  • 114
    • 34250761431 scopus 로고    scopus 로고
    • Inhibition of ABCG2-mediated transport by protein kinase inhibitors with a bisindolylmaleimide or indolocarbazole structure
    • DOI 10.1158/1535-7163.MCT-06-0811
    • Robey RW, Shukla S, Steadman K, et al. Inhibition of ABCG2-mediated transport by protein kinase inhibitors with a bisindolylmaleimide or indolocarbazole structure. Mol Cancer Ther. 2007;6(6):1877-1885. (Pubitemid 46954065)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.6 , pp. 1877-1885
    • Robey, R.W.1    Shukla, S.2    Steadman, K.3    Obrzut, T.4    Finley, E.M.5    Ambudkar, S.V.6    Bates, S.E.7
  • 115
    • 64349122714 scopus 로고    scopus 로고
    • Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar
    • Kuhnle M, Egger M, Muller C, et al. Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. J Med Chem. 2009;52(4):1190-1197.
    • (2009) J Med Chem , vol.52 , Issue.4 , pp. 1190-1197
    • Kuhnle, M.1    Egger, M.2    Muller, C.3
  • 117
    • 58549108859 scopus 로고    scopus 로고
    • The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
    • Dubrovska A, Kim S, Salamone RJ, et al. The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proc Natl Acad Sci U S A. 2009;106(1):268-273.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.1 , pp. 268-273
    • Dubrovska, A.1    Kim, S.2    Salamone, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.