Selenium-enhanced electron microscopic imaging of different aggregate forms of a segment of the amyloid β peptide in cells

ACS Nano

Volumn 6, Issue 6, 2012, Pages 4740-4747

  McGuire, Eva K ^a   Motskin, Michael ^b   Bolognesi, Benedetta ^b   Bergin, Shane D ^a   Knowles, Tuomas P J ^b   Skepper, Jeremy ^b   Luheshi, Leila M ^b   McComb, David W ^a,c   Dobson, Christopher M ^b   Porter, Alexandra E ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c The Ohio State University   (United States)

Author keywords

amyloid ; cytotoxicity; electron microscopy; macrophages; neurodegeneration

Indexed keywords

AGE-RELATED; ALZHEIMER'S; ALZHEIMER'S DISEASE; HUMAN MACROPHAGES; IN-SITU; MICROSCOPIC IMAGING; MISFOLDED PROTEINS; MOLECULAR ORIGINS; MORPHOLOGICAL CHANGES; NEURODEGENERATION; PARKINSON'S DISEASE; PROTEIN AGGREGATES; PROTEIN ASSEMBLY; SPECIFIC INFORMATION; SUBCELLULAR COMPARTMENTS; TOMOGRAPHIC RECONSTRUCTION;

CYTOTOXICITY; ELECTRON MICROSCOPES; ELECTRON MICROSCOPY; GLYCOPROTEINS; MACROPHAGES; PEPTIDES; SELENIUM;

AGGREGATES;

AMYLOID BETA PROTEIN; CONTRAST MEDIUM; DIAGNOSTIC AGENT; MULTIPROTEIN COMPLEX; SELENIUM;

ARTICLE; CELL CULTURE; CHEMISTRY; ELECTRON MICROSCOPY; HUMAN; IMAGE ENHANCEMENT; MACROPHAGE; METABOLISM; METHODOLOGY; PROTEIN BINDING; PROTEIN FOLDING; ULTRASTRUCTURE;

AMYLOID BETA-PEPTIDES; CELLS, CULTURED; CONTRAST MEDIA; HUMANS; IMAGE ENHANCEMENT; MACROPHAGES; MICROSCOPY, ELECTRON; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN FOLDING; SELENIUM;

EID: 84862863296     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn204859e     Document Type: Article

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