Uptake of C60 by human monocyte macrophages, its localization and implications for toxicity: Studied by high resolution electron microscopy and electron tomography

Acta Biomaterialia

Volumn 2, Issue 4, 2006, Pages 409-419

  Porter, Alexandra E ^a   Muller, Karin ^a   Skepper, Jeremy ^a   Midgley, Paul ^a   Welland, Mark ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

3 D electron tomography; Buckminster fullerene; Intracellular distributions; Toxicity

Indexed keywords

BODY FLUIDS; CELL MEMBRANES; CYTOLOGY; ELECTRIC IMPEDANCE TOMOGRAPHY; ELECTRONS; FREE RADICALS; FULLERENES; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; MACROPHAGES; NANOPARTICLES; SCANNING ELECTRON MICROSCOPY;

3-D ELECTRON TOMOGRAPHY; BUCKMINSTERFULLERENES; C 60; D ELECTRONS; ELECTRON TOMOGRAPHY; ENERGY FILTERED TRANSMISSION ELECTRON MICROSCOPY; HUMAN MONOCYTES; INTRACELLULAR DISTRIBUTION; MONOCYTE-MACROPHAGES; SCANNING TRANSMISSION ELECTRON MICROSCOPY;

TOXICITY;

CARBON; FREE RADICAL; NANOPARTICLE; FULLERENE DERIVATIVE; NANOMATERIAL;

ARTICLE; CELL COMPARTMENTALIZATION; CELL NUCLEUS MEMBRANE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CHEMICAL MODIFICATION; CYTOTOXICITY; ENERGY FILTERED TRANSMISSION ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; INTERNALIZATION; LYSOSOME; MACROPHAGE; MONOCYTE; PREDICTION; PRIORITY JOURNAL; SCANNING TRANSMISSION ELECTRON MICROSCOPY; STAINING; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING; WHOLE CELL; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FREEZE DRYING; METABOLISM; TOMOGRAPHY; ULTRASTRUCTURE;

CELL CULTURE TECHNIQUES; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FREEZE DRYING; FULLERENES; HUMANS; IMAGING, THREE-DIMENSIONAL; MACROPHAGES; MICROSCOPY, ENERGY-FILTERING TRANSMISSION ELECTRON; MONOCYTES; NANOSTRUCTURES; TOMOGRAPHY;

EID: 33744780459     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2006.02.006     Document Type: Article

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