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Volumn 37, Issue 8, 2012, Pages 1248-1260

GPR30 is necessary for estradiol-induced desensitization of 5-HT 1A receptor signaling in the paraventricular nucleus of the rat hypothalamus

Author keywords

5 HT 1A receptors; ACTH; Desensitization; Estradiol; GPER; GPR30; Oxytocin; Paraventricular nucleus; RGSz1

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ADENOVIRUS VECTOR; ESTRADIOL BENZOATE; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR BETA; G PROTEIN COUPLED RECEPTOR 30; MESSENGER RNA; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SMALL INTERFERING RNA;

EID: 84862818880     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2011.12.018     Document Type: Article
Times cited : (27)

References (89)
  • 2
    • 33847755409 scopus 로고    scopus 로고
    • G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    • Albanito L., Madeo A., Lappano R., Vivacqua A., Rago V., Carpino A., Oprea T.I., Prossnitz E.R., Musti A.M., Ando S., Maggiolini M. G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res. 2007, 67:1859-1866.
    • (2007) Cancer Res. , vol.67 , pp. 1859-1866
    • Albanito, L.1    Madeo, A.2    Lappano, R.3    Vivacqua, A.4    Rago, V.5    Carpino, A.6    Oprea, T.I.7    Prossnitz, E.R.8    Musti, A.M.9    Ando, S.10    Maggiolini, M.11
  • 3
    • 0032539948 scopus 로고    scopus 로고
    • Differential colocalization of estrogen receptor beta (ERbeta) with oxytocin and vasopressin in the paraventricular and supraoptic nuclei of the female rat brain: an immunocytochemical study
    • Alves S.E., Lopez V., McEwen B.S., Weiland N.G. Differential colocalization of estrogen receptor beta (ERbeta) with oxytocin and vasopressin in the paraventricular and supraoptic nuclei of the female rat brain: an immunocytochemical study. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:3281-3286.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 3281-3286
    • Alves, S.E.1    Lopez, V.2    McEwen, B.S.3    Weiland, N.G.4
  • 4
    • 0032845731 scopus 로고    scopus 로고
    • A randomized comparison of continuous combined transdermal delivery of estradiol-norethindrone acetate and estradiol alone for menopause. CombiPatch Study Group
    • Archer D.F., Furst K., Tipping D., Dain M.P., Vandepol C. A randomized comparison of continuous combined transdermal delivery of estradiol-norethindrone acetate and estradiol alone for menopause. CombiPatch Study Group. Obstet. Gynecol. 1999, 94:498-503.
    • (1999) Obstet. Gynecol. , vol.94 , pp. 498-503
    • Archer, D.F.1    Furst, K.2    Tipping, D.3    Dain, M.P.4    Vandepol, C.5
  • 5
    • 0029813566 scopus 로고    scopus 로고
    • The female brain hypoestrogenic continuum from the premenstrual syndrome to menopause. A hypothesis and review of supporting data
    • Arpels J.C. The female brain hypoestrogenic continuum from the premenstrual syndrome to menopause. A hypothesis and review of supporting data. J. Reprod. Med. 1996, 41:633-639.
    • (1996) J. Reprod. Med. , vol.41 , pp. 633-639
    • Arpels, J.C.1
  • 6
    • 0037090662 scopus 로고    scopus 로고
    • Affective syndrome during perimenopause
    • Banger M. Affective syndrome during perimenopause. Maturitas 2002, 41(Suppl. 1):S13-S18.
    • (2002) Maturitas , vol.41 , Issue.SUPPL. 1
    • Banger, M.1
  • 7
    • 0031029553 scopus 로고    scopus 로고
    • Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor.G protein coupling
    • Barr A.J., Brass L.F., Manning D.R. Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor.G protein coupling. J. Biol. Chem. 1997, 272:2223-2229.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2223-2229
    • Barr, A.J.1    Brass, L.F.2    Manning, D.R.3
  • 8
    • 80052265975 scopus 로고    scopus 로고
    • Long-term ovariectomy decreases serotonin neuron number and gene expression in free ranging macaques
    • Bethea C.L., Smith A.W., Centeno M.L., Reddy A.P. Long-term ovariectomy decreases serotonin neuron number and gene expression in free ranging macaques. Neuroscience 2011, 192:675-688.
    • (2011) Neuroscience , vol.192 , pp. 675-688
    • Bethea, C.L.1    Smith, A.W.2    Centeno, M.L.3    Reddy, A.P.4
  • 9
    • 0034902614 scopus 로고    scopus 로고
    • Serotonin 5-HT(1A) receptor mRNA expression in dorsal hippocampus and raphe nuclei after gonadal hormone manipulation in female rats
    • Birzniece V., Johansson I.M., Wang M.D., Seckl J.R., Backstrom T., Olsson T. Serotonin 5-HT(1A) receptor mRNA expression in dorsal hippocampus and raphe nuclei after gonadal hormone manipulation in female rats. Neuroendocrinology 2001, 74:135-142.
    • (2001) Neuroendocrinology , vol.74 , pp. 135-142
    • Birzniece, V.1    Johansson, I.M.2    Wang, M.D.3    Seckl, J.R.4    Backstrom, T.5    Olsson, T.6
  • 10
    • 0028287265 scopus 로고
    • Current advances and trends in the treatment of depression
    • Blier P., de Montigny C. Current advances and trends in the treatment of depression. Trends Pharmacol. Sci. 1994, 7:220-226.
    • (1994) Trends Pharmacol. Sci. , vol.7 , pp. 220-226
    • Blier, P.1    de Montigny, C.2
  • 11
    • 0034465071 scopus 로고    scopus 로고
    • An estrogen receptor-alpha splicing variant mediates both positive and negative effects on gene transcription
    • Bollig A., Miksicek R.J. An estrogen receptor-alpha splicing variant mediates both positive and negative effects on gene transcription. Mol. Endocrinol. 2000, 14:634-649.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 634-649
    • Bollig, A.1    Miksicek, R.J.2
  • 12
    • 0035109054 scopus 로고    scopus 로고
    • Acute and chronic effects of citalopram on postsynaptic 5-hydroxytryptamine(1A) receptor-mediated feedback: a microdialysis study in the amygdala
    • Bosker F.J., Cremers T.I., Jongsma M.E., Westerink B.H., Wikstrom H.V., den Boer J.A. Acute and chronic effects of citalopram on postsynaptic 5-hydroxytryptamine(1A) receptor-mediated feedback: a microdialysis study in the amygdala. J. Neurochem. 2001, 76:1645-1653.
    • (2001) J. Neurochem. , vol.76 , pp. 1645-1653
    • Bosker, F.J.1    Cremers, T.I.2    Jongsma, M.E.3    Westerink, B.H.4    Wikstrom, H.V.5    den Boer, J.A.6
  • 13
    • 34250322219 scopus 로고    scopus 로고
    • Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system
    • Brailoiu E., Dun S.L., Brailoiu G.C., Mizuo K., Sklar L.A., Oprea T.I., Prossnitz E.R., Dun N.J. Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. J. Endocrinol. 2007, 193:311-321.
    • (2007) J. Endocrinol. , vol.193 , pp. 311-321
    • Brailoiu, E.1    Dun, S.L.2    Brailoiu, G.C.3    Mizuo, K.4    Sklar, L.A.5    Oprea, T.I.6    Prossnitz, E.R.7    Dun, N.J.8
  • 14
    • 3242740288 scopus 로고    scopus 로고
    • Estrogen treatment increases the levels of regulator of G protein signaling-Z1 in the hypothalamic paraventricular nucleus: possible role in desensitization of 5-hydroxytryptamine1A receptors
    • Carrasco G.A., Barker S.A., Zhang Y., Damjanoska K.J., Sullivan N.R., Garcia F., D'Souza D., Muma N., van De Kar N.A.L.D. Estrogen treatment increases the levels of regulator of G protein signaling-Z1 in the hypothalamic paraventricular nucleus: possible role in desensitization of 5-hydroxytryptamine1A receptors. Neuroscience 2004, 127:261-267.
    • (2004) Neuroscience , vol.127 , pp. 261-267
    • Carrasco, G.A.1    Barker, S.A.2    Zhang, Y.3    Damjanoska, K.J.4    Sullivan, N.R.5    Garcia, F.6    D'Souza, D.7    Muma, N.8    van De Kar, N.A.L.D.9
  • 15
    • 0022454164 scopus 로고
    • Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: electrophysiological studies in the rat brain
    • Chaput Y., de Montigny C., Blier P. Effects of a selective 5-HT reuptake blocker, citalopram, on the sensitivity of 5-HT autoreceptors: electrophysiological studies in the rat brain. Naunyn Schmiedebergs Arch. Pharmakol. 1986, 333:342-348.
    • (1986) Naunyn Schmiedebergs Arch. Pharmakol. , vol.333 , pp. 342-348
    • Chaput, Y.1    de Montigny, C.2    Blier, P.3
  • 16
    • 0033864136 scopus 로고    scopus 로고
    • Effects of acute and chronic administration of fluoxetine on the activity of serotonergic neurons in the dorsal raphe nucleus of the rat
    • Czachura J.F., Rasmussen K. Effects of acute and chronic administration of fluoxetine on the activity of serotonergic neurons in the dorsal raphe nucleus of the rat. Naunyn Schmiedebergs Arch. Pharmakol. 2000, 362:266-275.
    • (2000) Naunyn Schmiedebergs Arch. Pharmakol. , vol.362 , pp. 266-275
    • Czachura, J.F.1    Rasmussen, K.2
  • 18
    • 65249169711 scopus 로고    scopus 로고
    • 17beta-estradiol-mediated neuroprotection and ERK activation require a pertussis toxin-sensitive mechanism involving GRK2 and beta-arrestin-1
    • Dominguez R., Hu E., Zhou M., Baudry M. 17beta-estradiol-mediated neuroprotection and ERK activation require a pertussis toxin-sensitive mechanism involving GRK2 and beta-arrestin-1. J. Neurosci. 2009, 29:4228-4238.
    • (2009) J. Neurosci. , vol.29 , pp. 4228-4238
    • Dominguez, R.1    Hu, E.2    Zhou, M.3    Baudry, M.4
  • 19
    • 77957200484 scopus 로고    scopus 로고
    • Estradiol rapidly regulates membrane estrogen receptor alpha levels in hypothalamic neurons
    • Dominguez R., Micevych P. Estradiol rapidly regulates membrane estrogen receptor alpha levels in hypothalamic neurons. J. Neurosci. 2010, 30:12589-12596.
    • (2010) J. Neurosci. , vol.30 , pp. 12589-12596
    • Dominguez, R.1    Micevych, P.2
  • 20
    • 0036127836 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor GPR30: a novel signaling pathway with potential significance for breast cancer
    • Filardo E.J. Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor GPR30: a novel signaling pathway with potential significance for breast cancer. J. Steroid. Biochem. 2002, 80:231-238.
    • (2002) J. Steroid. Biochem. , vol.80 , pp. 231-238
    • Filardo, E.J.1
  • 21
    • 33751272253 scopus 로고    scopus 로고
    • Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression
    • Filardo E.J., Graeber C.T., Quinn J.A., Resnick M.B., Giri D., DeLellis R.A., Steinhoff M.M., Sabo E. Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression. Clin. Cancer Res. 2006, 6359-6366.
    • (2006) Clin. Cancer Res. , pp. 6359-6366
    • Filardo, E.J.1    Graeber, C.T.2    Quinn, J.A.3    Resnick, M.B.4    Giri, D.5    DeLellis, R.A.6    Steinhoff, M.M.7    Sabo, E.8
  • 22
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo E.J., Quinn J.A., Bland K.I., Frackelton A.R. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol. Endocrinol. 2000, 14:1649-1660.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton, A.R.4
  • 24
    • 0032475518 scopus 로고    scopus 로고
    • RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha
    • Glick J.L., Meigs T.E., Miron A., Casey P.J. RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha. J. Biol. Chem. 1998, 273:26008-26013.
    • (1998) J. Biol. Chem. , vol.273 , pp. 26008-26013
    • Glick, J.L.1    Meigs, T.E.2    Miron, A.3    Casey, P.J.4
  • 26
    • 45849083496 scopus 로고    scopus 로고
    • Estrogen receptor alpha is expressed on the cell-surface of embryonic hypothalamic neurons
    • Gorosito S.V., Lorenzo A.G., Cambiasso M.J. Estrogen receptor alpha is expressed on the cell-surface of embryonic hypothalamic neurons. Neuroscience 2008, 154:1173-1177.
    • (2008) Neuroscience , vol.154 , pp. 1173-1177
    • Gorosito, S.V.1    Lorenzo, A.G.2    Cambiasso, M.J.3
  • 27
    • 49749106227 scopus 로고    scopus 로고
    • Effects of chronic citalopram treatment on 5-HT1A and 5-HT2A receptors in group- and isolation-housed mice
    • Gunther L., Liebscher S., Jahkel M., Oehler J. Effects of chronic citalopram treatment on 5-HT1A and 5-HT2A receptors in group- and isolation-housed mice. Eur. J. Pharmacol. 2008, 593:49-61.
    • (2008) Eur. J. Pharmacol. , vol.593 , pp. 49-61
    • Gunther, L.1    Liebscher, S.2    Jahkel, M.3    Oehler, J.4
  • 28
    • 0025001409 scopus 로고
    • Gonadal hormones and antihormones, serotonin and mood
    • Halbreich U. Gonadal hormones and antihormones, serotonin and mood. Psychopharmacol. Bull. 1990, 26:291-295.
    • (1990) Psychopharmacol. Bull. , vol.26 , pp. 291-295
    • Halbreich, U.1
  • 29
    • 0037225061 scopus 로고    scopus 로고
    • Depression and its influence on reproductive endocrine and menstrual cycle markers associated with perimenopause: the Harvard Study of Moods and Cycles
    • Harlow B.L., Wise L.A., Otto M.W., Soares C.N., Cohen L.S. Depression and its influence on reproductive endocrine and menstrual cycle markers associated with perimenopause: the Harvard Study of Moods and Cycles. Arch. Gen. Psychiatry 2003, 60:29-36.
    • (2003) Arch. Gen. Psychiatry , vol.60 , pp. 29-36
    • Harlow, B.L.1    Wise, L.A.2    Otto, M.W.3    Soares, C.N.4    Cohen, L.S.5
  • 31
    • 67449088240 scopus 로고    scopus 로고
    • Differential effects of ovarian steroids and raloxifene on serotonin 1A and 2C receptor protein expression in macaques
    • Henderson J.A., Bethea C.L. Differential effects of ovarian steroids and raloxifene on serotonin 1A and 2C receptor protein expression in macaques. Endocrine 2008, 33:285-293.
    • (2008) Endocrine , vol.33 , pp. 285-293
    • Henderson, J.A.1    Bethea, C.L.2
  • 32
    • 0033492916 scopus 로고    scopus 로고
    • The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes
    • Hendricks T., Francis N., Fyodorov D., Deneris E.S. The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes. J. Neurosci. 1999, 19:10348-10356.
    • (1999) J. Neurosci. , vol.19 , pp. 10348-10356
    • Hendricks, T.1    Francis, N.2    Fyodorov, D.3    Deneris, E.S.4
  • 34
    • 2342645615 scopus 로고    scopus 로고
    • Estrogen receptor-beta in oxytocin and vasopressin neurons of the rat and human hypothalamus: immunocytochemical and in situ hybridization studies
    • Hrabovszky E., Kallo I., Steinhauser A., Merchenthaler I., Coen C.W., Petersen S.L., Liposits Z. Estrogen receptor-beta in oxytocin and vasopressin neurons of the rat and human hypothalamus: immunocytochemical and in situ hybridization studies. J. Comp. Neurol. 2004, 473:315-333.
    • (2004) J. Comp. Neurol. , vol.473 , pp. 315-333
    • Hrabovszky, E.1    Kallo, I.2    Steinhauser, A.3    Merchenthaler, I.4    Coen, C.W.5    Petersen, S.L.6    Liposits, Z.7
  • 35
    • 38349129612 scopus 로고    scopus 로고
    • Estrogen receptor-alpha splice variants in the human brain
    • Ishunina T.A., Swaab D.F. Estrogen receptor-alpha splice variants in the human brain. Gynecol. Endocrinol. 2008, 24:93-98.
    • (2008) Gynecol. Endocrinol. , vol.24 , pp. 93-98
    • Ishunina, T.A.1    Swaab, D.F.2
  • 36
    • 23044443958 scopus 로고    scopus 로고
    • Regional distribution and cellular localization of the ETS-domain transcription factor FEV, mRNA in the human postmortem brain
    • Iyo A.H., Porter B., Deneris E.S., Austin M.C. Regional distribution and cellular localization of the ETS-domain transcription factor FEV, mRNA in the human postmortem brain. Synapse 2005, 57:223-228.
    • (2005) Synapse , vol.57 , pp. 223-228
    • Iyo, A.H.1    Porter, B.2    Deneris, E.S.3    Austin, M.C.4
  • 37
    • 0030175654 scopus 로고    scopus 로고
    • Prior treatment with estrogen attenuates the effects of the 5-HT1A agonist, 8-OH-DPAT, on lordosis behavior
    • Jackson A., Uphouse L. Prior treatment with estrogen attenuates the effects of the 5-HT1A agonist, 8-OH-DPAT, on lordosis behavior. Horm. Behav. 1996, 30:145-152.
    • (1996) Horm. Behav. , vol.30 , pp. 145-152
    • Jackson, A.1    Uphouse, L.2
  • 38
    • 0032526577 scopus 로고    scopus 로고
    • Dose-dependent effects of estradiol benzoate on 5-HT1A receptor agonist action
    • Jackson A., Uphouse L. Dose-dependent effects of estradiol benzoate on 5-HT1A receptor agonist action. Brain Res. 1998, 796:299-302.
    • (1998) Brain Res. , vol.796 , pp. 299-302
    • Jackson, A.1    Uphouse, L.2
  • 39
    • 79952438213 scopus 로고    scopus 로고
    • Region-specific regulation of 5-HT1A receptor expression by Pet-1-dependent mechanisms in vivo
    • Jacobsen K.X., Czesak M., Deria M., Le Francois B., Albert P.R. Region-specific regulation of 5-HT1A receptor expression by Pet-1-dependent mechanisms in vivo. J. Neurochem. 2011, 116:1066-1076.
    • (2011) J. Neurochem. , vol.116 , pp. 1066-1076
    • Jacobsen, K.X.1    Czesak, M.2    Deria, M.3    Le Francois, B.4    Albert, P.R.5
  • 42
    • 0032213226 scopus 로고    scopus 로고
    • Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge?
    • Joffe H., Cohen L.S. Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge?. Biol. Psychiatry 1998, 44:798-811.
    • (1998) Biol. Psychiatry , vol.44 , pp. 798-811
    • Joffe, H.1    Cohen, L.S.2
  • 43
    • 77950407928 scopus 로고    scopus 로고
    • Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling
    • Kang L., Zhang X., Xie Y., Tu Y., Wang D., Liu Z., Wang Z.Y. Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling. Mol. Endocrinol. 2010, 24:709-721.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 709-721
    • Kang, L.1    Zhang, X.2    Xie, Y.3    Tu, Y.4    Wang, D.5    Liu, Z.6    Wang, Z.Y.7
  • 44
    • 0032487057 scopus 로고    scopus 로고
    • Expression and neuropeptidergic characterization of estrogen receptors (ERalpha and ERbeta) throughout the rat brain: anatomical evidence of distinct roles of each subtype
    • Laflamme N., Nappi R.E., Drolet G., Labrie C., Rivest S. Expression and neuropeptidergic characterization of estrogen receptors (ERalpha and ERbeta) throughout the rat brain: anatomical evidence of distinct roles of each subtype. J. Neurobiol. 1998, 36:357-378.
    • (1998) J. Neurobiol. , vol.36 , pp. 357-378
    • Laflamme, N.1    Nappi, R.E.2    Drolet, G.3    Labrie, C.4    Rivest, S.5
  • 45
    • 40549117168 scopus 로고    scopus 로고
    • ER-alpha36, a novel variant of ER-alpha, is expressed in ER-positive and -negative human breast carcinomas
    • Lee L.M., Cao J., Deng H., Chen P., Gatalica Z., Wang Z.Y. ER-alpha36, a novel variant of ER-alpha, is expressed in ER-positive and -negative human breast carcinomas. Anticancer Res. 2008, 28:479-483.
    • (2008) Anticancer Res. , vol.28 , pp. 479-483
    • Lee, L.M.1    Cao, J.2    Deng, H.3    Chen, P.4    Gatalica, Z.5    Wang, Z.Y.6
  • 47
    • 0033137334 scopus 로고    scopus 로고
    • 5-HT1A receptor function in normal subjects on clinical doses of fluoxetine: blunted temperature and hormone responses to ipsapirone challenge
    • Lerer B., Gelfin Y., Gorfine M., Allolio B., Lesch K.P., Newman M.E. 5-HT1A receptor function in normal subjects on clinical doses of fluoxetine: blunted temperature and hormone responses to ipsapirone challenge. Neuropsychopharmacology 1999, 20:628-639.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 628-639
    • Lerer, B.1    Gelfin, Y.2    Gorfine, M.3    Allolio, B.4    Lesch, K.P.5    Newman, M.E.6
  • 48
    • 0025918115 scopus 로고
    • 5-HT1A receptor responsivity in anxiety disorders and depression
    • Lesch K.P. 5-HT1A receptor responsivity in anxiety disorders and depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 1991, 15:723-733.
    • (1991) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.15 , pp. 723-733
    • Lesch, K.P.1
  • 49
    • 0037446887 scopus 로고    scopus 로고
    • Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells
    • Li L., Haynes M.P., Bender J.R. Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:4807-4812.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 4807-4812
    • Li, L.1    Haynes, M.P.2    Bender, J.R.3
  • 50
    • 0027386157 scopus 로고
    • Long-term fluoxetine, but not desipramine, inhibits the ACTH and oxytocin responses to the 5-HT1A agonist, 8-OH-DPAT, in male rats
    • Li Q., Levy A.D., Cabrera T.M., Brownfield M.S., Battaglia G., Van de Kar L.D. Long-term fluoxetine, but not desipramine, inhibits the ACTH and oxytocin responses to the 5-HT1A agonist, 8-OH-DPAT, in male rats. Brain Res. 1993, 630:148-156.
    • (1993) Brain Res. , vol.630 , pp. 148-156
    • Li, Q.1    Levy, A.D.2    Cabrera, T.M.3    Brownfield, M.S.4    Battaglia, G.5    Van de Kar, L.D.6
  • 51
    • 0030967945 scopus 로고    scopus 로고
    • A desensitization of hypothalamic 5-HT1A receptors by repeated injections of paroxetine: reduction in the levels of G(i) and G(o) proteins and neuroendocrine responses, but not in the density of 5-HT1A receptors
    • Li Q., Muma N.A., Battaglia G., Van de Kar L.D. A desensitization of hypothalamic 5-HT1A receptors by repeated injections of paroxetine: reduction in the levels of G(i) and G(o) proteins and neuroendocrine responses, but not in the density of 5-HT1A receptors. J. Pharm. Exp. Ther. 1997, 282:1581-1590.
    • (1997) J. Pharm. Exp. Ther. , vol.282 , pp. 1581-1590
    • Li, Q.1    Muma, N.A.2    Battaglia, G.3    Van de Kar, L.D.4
  • 52
    • 0030433045 scopus 로고    scopus 로고
    • Chronic fluoxetine induces a gradual desensitization of 5-HT1A receptors: reductions in hypothalamic and midbrain Gi and G(o) proteins and in neuroendocrine responses to a 5-HT1A agonist
    • Li Q., Muma N.A., van de Kar L.D. Chronic fluoxetine induces a gradual desensitization of 5-HT1A receptors: reductions in hypothalamic and midbrain Gi and G(o) proteins and in neuroendocrine responses to a 5-HT1A agonist. J. Pharm. Exp. Ther. 1996, 279:1035-1042.
    • (1996) J. Pharm. Exp. Ther. , vol.279 , pp. 1035-1042
    • Li, Q.1    Muma, N.A.2    van de Kar, L.D.3
  • 53
    • 0027262653 scopus 로고
    • Postmenopausal hot flushes and their management
    • Lomax P., Schonbaum E. Postmenopausal hot flushes and their management. Pharmacol. Ther. 1993, 57:347-358.
    • (1993) Pharmacol. Ther. , vol.57 , pp. 347-358
    • Lomax, P.1    Schonbaum, E.2
  • 54
    • 0036279353 scopus 로고    scopus 로고
    • Ovarian steroid regulation of 5-HT1A receptor binding and G protein activation in female monkeys
    • Lu N.Z., Bethea C.L. Ovarian steroid regulation of 5-HT1A receptor binding and G protein activation in female monkeys. Neuropsychopharmacology 2002, 27:12-24.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 12-24
    • Lu, N.Z.1    Bethea, C.L.2
  • 58
    • 0034708540 scopus 로고    scopus 로고
    • Acute and long-term effects of 17beta-estradiol on G(i/o) coupled neurotransmitter receptor function in the female rat brain as assessed by agonist-stimulated [35S]GTPgammaS binding
    • Mize A.L., Alper R.H. Acute and long-term effects of 17beta-estradiol on G(i/o) coupled neurotransmitter receptor function in the female rat brain as assessed by agonist-stimulated [35S]GTPgammaS binding. Brain Res. 2000, 859:326-333.
    • (2000) Brain Res. , vol.859 , pp. 326-333
    • Mize, A.L.1    Alper, R.H.2
  • 59
    • 34247267144 scopus 로고    scopus 로고
    • Effects of citalopram treatment on hypothermic and hormonal responses to the 5-HT1A receptor agonist buspirone in patients with major depression and therapeutic response
    • Navines R., Martin-Santos R., Gomez-Gil E., Martinez de Osaba M.J., Imaz M.L., Gasto C. Effects of citalopram treatment on hypothermic and hormonal responses to the 5-HT1A receptor agonist buspirone in patients with major depression and therapeutic response. Psychoneuroendocrinology 2007, 32:411-416.
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 411-416
    • Navines, R.1    Martin-Santos, R.2    Gomez-Gil, E.3    Martinez de Osaba, M.J.4    Imaz, M.L.5    Gasto, C.6
  • 60
    • 25844518335 scopus 로고    scopus 로고
    • Long-term citalopram administration reduces responsiveness of HPA axis in patients with major depression: relationship with S-citalopram concentrations in plasma and cerebrospinal fluid (CSF) and clinical response
    • Nikisch G., Mathe A.A., Czernik A., Thiele J., Bohner J., Eap C.B., Agren H., Baumann P. Long-term citalopram administration reduces responsiveness of HPA axis in patients with major depression: relationship with S-citalopram concentrations in plasma and cerebrospinal fluid (CSF) and clinical response. Psychopharmacology 2005, 181:751-760.
    • (2005) Psychopharmacology , vol.181 , pp. 751-760
    • Nikisch, G.1    Mathe, A.A.2    Czernik, A.3    Thiele, J.4    Bohner, J.5    Eap, C.B.6    Agren, H.7    Baumann, P.8
  • 61
    • 19444373123 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine 1A receptors in the paraventricular nucleus of the hypothalamus mediate oxytocin and adrenocorticotropin hormone release and some behavioral components of the serotonin syndrome
    • Osei-Owusu P., James A., Crane J., Scrogin K.E. 5-Hydroxytryptamine 1A receptors in the paraventricular nucleus of the hypothalamus mediate oxytocin and adrenocorticotropin hormone release and some behavioral components of the serotonin syndrome. J. Pharm. Exp. Ther. 2005, 313:1324-1330.
    • (2005) J. Pharm. Exp. Ther. , vol.313 , pp. 1324-1330
    • Osei-Owusu, P.1    James, A.2    Crane, J.3    Scrogin, K.E.4
  • 62
    • 0032579761 scopus 로고    scopus 로고
    • Acute 17 beta-estradiol treatment down-regulates serotonin 5HT1A receptor mRNA expression in the limbic system of female rats
    • Osterlund M.K., Hurd Y.L. Acute 17 beta-estradiol treatment down-regulates serotonin 5HT1A receptor mRNA expression in the limbic system of female rats. Brain Res. Mol. Brain Res. 1998, 55:169-172.
    • (1998) Brain Res. Mol. Brain Res. , vol.55 , pp. 169-172
    • Osterlund, M.K.1    Hurd, Y.L.2
  • 63
    • 79960908086 scopus 로고    scopus 로고
    • Differential vasoactive effects of oestrogen, oestrogen receptor agonists and selective oestrogen receptor modulators in rat middle cerebral artery
    • Patkar S., Farr T.D., Cooper E., Dowell F.J., Carswell H.V. Differential vasoactive effects of oestrogen, oestrogen receptor agonists and selective oestrogen receptor modulators in rat middle cerebral artery. Neurosci. Res. 2011, 71:78-84.
    • (2011) Neurosci. Res. , vol.71 , pp. 78-84
    • Patkar, S.1    Farr, T.D.2    Cooper, E.3    Dowell, F.J.4    Carswell, H.V.5
  • 64
    • 0033105944 scopus 로고    scopus 로고
    • Ovarian steroid regulation of serotonin-1A autoreceptor messenger RNA expression in the dorsal raphe of rhesus macaques
    • Pecins-Thompson M., Bethea C.L. Ovarian steroid regulation of serotonin-1A autoreceptor messenger RNA expression in the dorsal raphe of rhesus macaques. Neuroscience 1999, 89:267-277.
    • (1999) Neuroscience , vol.89 , pp. 267-277
    • Pecins-Thompson, M.1    Bethea, C.L.2
  • 65
    • 0034045736 scopus 로고    scopus 로고
    • Estrogen desensitizes 5-HT(1A) receptors and reduces levels of G(z) G(i1) and G(i3) proteins in the hypothalamus
    • Raap D.K., DonCarlos L., Garcia F., Muma N.A., Wolf W.A., Battaglia G., Van de Kar L.D. Estrogen desensitizes 5-HT(1A) receptors and reduces levels of G(z) G(i1) and G(i3) proteins in the hypothalamus. Neuropharmacology 2000, 39:1823-1832.
    • (2000) Neuropharmacology , vol.39 , pp. 1823-1832
    • Raap, D.K.1    DonCarlos, L.2    Garcia, F.3    Muma, N.A.4    Wolf, W.A.5    Battaglia, G.6    Van de Kar, L.D.7
  • 66
    • 0032914750 scopus 로고    scopus 로고
    • Daily injections of fluoxetine induce dose-dependent desensitization of hypothalamic 5-HT1A receptors: reductions in neuroendocrine responses to 8-OH-DPAT and in levels of Gz and Gi proteins
    • Raap D.K., Evans S., Garcia F., Li Q., Muma N.A., Wolf W.A., Battaglia G., Van De Kar L.D. Daily injections of fluoxetine induce dose-dependent desensitization of hypothalamic 5-HT1A receptors: reductions in neuroendocrine responses to 8-OH-DPAT and in levels of Gz and Gi proteins. J. Pharm. Exp. Ther. 1999, 288:98-106.
    • (1999) J. Pharm. Exp. Ther. , vol.288 , pp. 98-106
    • Raap, D.K.1    Evans, S.2    Garcia, F.3    Li, Q.4    Muma, N.A.5    Wolf, W.A.6    Battaglia, G.7    Van De Kar, L.D.8
  • 67
    • 0027522086 scopus 로고
    • Cell-specific physical and functional coupling of human 5-HT1A receptors to inhibitory G protein alpha-subunits and lack of coupling to Gs alpha
    • Raymond J.R., Olsen C.L., Gettys T.W. Cell-specific physical and functional coupling of human 5-HT1A receptors to inhibitory G protein alpha-subunits and lack of coupling to Gs alpha. Biochemistry 1993, 32:11064-11073.
    • (1993) Biochemistry , vol.32 , pp. 11064-11073
    • Raymond, J.R.1    Olsen, C.L.2    Gettys, T.W.3
  • 68
    • 0033765025 scopus 로고    scopus 로고
    • Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders
    • Ressler K.J., Nemeroff C.B. Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders. Depress. Anxiety 2000, 12(Suppl. 1):2-19.
    • (2000) Depress. Anxiety , vol.12 , Issue.SUPPL. 1 , pp. 2-19
    • Ressler, K.J.1    Nemeroff, C.B.2
  • 69
    • 14844343093 scopus 로고    scopus 로고
    • A transmembrane intracellular estrogen receptor mediates rapid cell signaling
    • Revankar C.M, Cimino D.F., Sklar L.A., Arterburn J.B., Prossnitz E.R. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 2005, 307:1625-1630.
    • (2005) Science , vol.307 , pp. 1625-1630
    • Revankar, C.M.1    Cimino, D.F.2    Sklar, L.A.3    Arterburn, J.B.4    Prossnitz, E.R.5
  • 70
    • 61549109572 scopus 로고    scopus 로고
    • Estradiol increases Pet-1 and serotonin transporter mRNA in the midbrain raphe nuclei of ovariectomized rats
    • Rivera H.M., Oberbeck D.R., Kwon B., Houpt T.A., Eckel L.A. Estradiol increases Pet-1 and serotonin transporter mRNA in the midbrain raphe nuclei of ovariectomized rats. Brain Res. 2009, 1259:51-58.
    • (2009) Brain Res. , vol.1259 , pp. 51-58
    • Rivera, H.M.1    Oberbeck, D.R.2    Kwon, B.3    Houpt, T.A.4    Eckel, L.A.5
  • 71
    • 77954959473 scopus 로고    scopus 로고
    • Estradiol-induced desensitization of 5-HT1A receptor signaling in the paraventricular nucleus of the hypothalamus is independent of estrogen receptor-beta
    • Rossi D.V., Dai Y., Thomas P., Carrasco G.A., DonCarlos L.L., Muma N.A., Li Q. Estradiol-induced desensitization of 5-HT1A receptor signaling in the paraventricular nucleus of the hypothalamus is independent of estrogen receptor-beta. Psychoneuroendocrinology 2010, 35:1023-1033.
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 1023-1033
    • Rossi, D.V.1    Dai, Y.2    Thomas, P.3    Carrasco, G.A.4    DonCarlos, L.L.5    Muma, N.A.6    Li, Q.7
  • 73
    • 36348947509 scopus 로고    scopus 로고
    • Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei
    • Sakamoto H., Matsuda K., Hosokawa K., Nishi M., Morris J.F., Prossnitz E.R., Kawata M. Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei. Endocrinology 2007, 148:5842-5850.
    • (2007) Endocrinology , vol.148 , pp. 5842-5850
    • Sakamoto, H.1    Matsuda, K.2    Hosokawa, K.3    Nishi, M.4    Morris, J.F.5    Prossnitz, E.R.6    Kawata, M.7
  • 74
    • 0029970280 scopus 로고    scopus 로고
    • Characterization of reproductive hormonal dynamics in the perimenopause
    • Santoro N., Brown J.R., Adel T., Skurnick J.H. Characterization of reproductive hormonal dynamics in the perimenopause. J. Clin. Endocr. Metab. 1996, 81:1495-1501.
    • (1996) J. Clin. Endocr. Metab. , vol.81 , pp. 1495-1501
    • Santoro, N.1    Brown, J.R.2    Adel, T.3    Skurnick, J.H.4
  • 76
    • 65049083026 scopus 로고    scopus 로고
    • 5-HT(1A) receptor function in major depressive disorder
    • Savitz J., Lucki I., Drevets W.C. 5-HT(1A) receptor function in major depressive disorder. Prog. Neurobiol. 2009, 88:17-31.
    • (2009) Prog. Neurobiol. , vol.88 , pp. 17-31
    • Savitz, J.1    Lucki, I.2    Drevets, W.C.3
  • 77
    • 9744223565 scopus 로고    scopus 로고
    • A longitudinal evaluation of the relationship between reproductive status and mood in perimenopausal women
    • Schmidt P.J., Haq N., Rubinow D.R. A longitudinal evaluation of the relationship between reproductive status and mood in perimenopausal women. Am. J. Psychiatry 2004, 161:2238-2244.
    • (2004) Am. J. Psychiatry , vol.161 , pp. 2238-2244
    • Schmidt, P.J.1    Haq, N.2    Rubinow, D.R.3
  • 78
    • 12644318801 scopus 로고    scopus 로고
    • Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial. Fluoxetine Collaborative Study Group
    • Schneider L.S., Small G.W., Hamilton S.H., Bystritsky A., Nemeroff C.B., Meyers B.S. Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial. Fluoxetine Collaborative Study Group. Am. J. Geriatr. Psychiatry 1997, 5:97-106.
    • (1997) Am. J. Geriatr. Psychiatry , vol.5 , pp. 97-106
    • Schneider, L.S.1    Small, G.W.2    Hamilton, S.H.3    Bystritsky, A.4    Nemeroff, C.B.5    Meyers, B.S.6
  • 80
    • 3042808672 scopus 로고    scopus 로고
    • Cognition, mood disorders, and sex hormones
    • Shively C.A., Bethea C.L. Cognition, mood disorders, and sex hormones. ILAR J. 2004, 45:189-199.
    • (2004) ILAR J. , vol.45 , pp. 189-199
    • Shively, C.A.1    Bethea, C.L.2
  • 81
    • 0030669205 scopus 로고    scopus 로고
    • Differential expression of estrogen receptor alpha and beta immunoreactivity by oxytocin neurons of rat paraventricular nucleus
    • Simonian S.X., Herbison A.E. Differential expression of estrogen receptor alpha and beta immunoreactivity by oxytocin neurons of rat paraventricular nucleus. J. Neuroendocrinol. 1997, 9:803-806.
    • (1997) J. Neuroendocrinol. , vol.9 , pp. 803-806
    • Simonian, S.X.1    Herbison, A.E.2
  • 83
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas P., Pang Y., Filardo E.J., Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 2005, 146:624-632.
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 84
    • 0032475515 scopus 로고    scopus 로고
    • RGSZ1, a Gz-selective RGS protein in brains Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily
    • Wang J., Ducret A., Tu Y., Kozasa T., Aebersold R., Ross E.M. RGSZ1, a Gz-selective RGS protein in brains Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily. J. Biol. Chem. 1998, 273:26014-26025.
    • (1998) J. Biol. Chem. , vol.273 , pp. 26014-26025
    • Wang, J.1    Ducret, A.2    Tu, Y.3    Kozasa, T.4    Aebersold, R.5    Ross, E.M.6
  • 85
    • 0037073785 scopus 로고    scopus 로고
    • Regulator of G protein signaling Z1 (RGSZ1) interacts with Galpha i subunits and regulates Galpha i-mediated cell signaling
    • Wang Y., Ho G., Zhang J.J., Nieuwenhuijsen B., Edris W., Chanda P.K., Young K.H. Regulator of G protein signaling Z1 (RGSZ1) interacts with Galpha i subunits and regulates Galpha i-mediated cell signaling. J. Biol. Chem. 2002, 277:48325-48332.
    • (2002) J. Biol. Chem. , vol.277 , pp. 48325-48332
    • Wang, Y.1    Ho, G.2    Zhang, J.J.3    Nieuwenhuijsen, B.4    Edris, W.5    Chanda, P.K.6    Young, K.H.7
  • 86
    • 25644437706 scopus 로고    scopus 로고
    • Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66
    • Wang Z., Zhang X., Shen P., Loggie B.W., Chang Y., Deuel T.F. Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66. Biochem. Biophys. Res. Commun. 2005, 336:1023-1027.
    • (2005) Biochem. Biophys. Res. Commun. , vol.336 , pp. 1023-1027
    • Wang, Z.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5    Deuel, T.F.6
  • 87
    • 33745160700 scopus 로고    scopus 로고
    • A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling
    • Wang Z., Zhang X., Shen P., Loggie B.W., Chang Y., Deuel T.F. A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:9063-9068.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 9063-9068
    • Wang, Z.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5    Deuel, T.F.6
  • 89
    • 64049115275 scopus 로고    scopus 로고
    • Estrogen receptor-alpha (ER-alpha) suppresses expression of its variant ER-alpha 36
    • Zou Y., Ding L., Coleman M., Wang Z. Estrogen receptor-alpha (ER-alpha) suppresses expression of its variant ER-alpha 36. FEBS Lett. 2009, 583:1368-1374.
    • (2009) FEBS Lett. , vol.583 , pp. 1368-1374
    • Zou, Y.1    Ding, L.2    Coleman, M.3    Wang, Z.4


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