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Volumn 192, Issue , 2011, Pages 675-688

Long-term ovariectomy decreases serotonin neuron number and gene expression in free ranging macaques

Author keywords

5HT1A autoreceptor; Estrogen; Fenfluramine; Fev; Progesterone; Serotonin reuptake transporter; TPH2

Indexed keywords

ESTRADIOL; FENFLURAMINE; PROGESTERONE; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE 2;

EID: 80052265975     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.06.003     Document Type: Article
Times cited : (31)

References (70)
  • 2
    • 0028997786 scopus 로고
    • Neurotrophins and the neuroendocrine brain: different neurotrophins sustain anatomically and functionally segregated subsets of hypothalamic dopaminergic neurons
    • Berg-von der Emde K., Dees W.L., Hiney J.K., Hill D.F., Dissen G.A., Costa M.E., Moholt-Siebert M., Ojeda S.R. Neurotrophins and the neuroendocrine brain: different neurotrophins sustain anatomically and functionally segregated subsets of hypothalamic dopaminergic neurons. J Neurosci 1995, 15:4223-4237.
    • (1995) J Neurosci , vol.15 , pp. 4223-4237
    • Berg-von der Emde, K.1    Dees, W.L.2    Hiney, J.K.3    Hill, D.F.4    Dissen, G.A.5    Costa, M.E.6    Moholt-Siebert, M.7    Ojeda, S.R.8
  • 3
    • 0028339305 scopus 로고
    • Regulation of progestin receptors in raphe neurons of steroid-treated monkeys
    • Bethea C.L. Regulation of progestin receptors in raphe neurons of steroid-treated monkeys. Neuroendocrinology 1994, 60:50-61.
    • (1994) Neuroendocrinology , vol.60 , pp. 50-61
    • Bethea, C.L.1
  • 4
    • 59049103855 scopus 로고    scopus 로고
    • Neurobiology of stress-induced reproductive dysfunction in female macaques
    • Bethea C.L., Centeno M.L., Cameron J.L. Neurobiology of stress-induced reproductive dysfunction in female macaques. Mol Neurobiol 2008, 38:199-230.
    • (2008) Mol Neurobiol , vol.38 , pp. 199-230
    • Bethea, C.L.1    Centeno, M.L.2    Cameron, J.L.3
  • 6
    • 11844269319 scopus 로고    scopus 로고
    • Sensitivity to stress-induced reproductive dysfunction linked to activity of the serotonin system
    • Bethea C.L., Pau F.K., Fox S., Hess D.L., Berga S.L., Cameron J.L. Sensitivity to stress-induced reproductive dysfunction linked to activity of the serotonin system. Fertil Steril 2005, 83:148-155.
    • (2005) Fertil Steril , vol.83 , pp. 148-155
    • Bethea, C.L.1    Pau, F.K.2    Fox, S.3    Hess, D.L.4    Berga, S.L.5    Cameron, J.L.6
  • 7
    • 42549151049 scopus 로고    scopus 로고
    • Effect of ovarian hormones on survival genes in laser captured serotonin neurons from macaques
    • Bethea C.L., Reddy A.P. Effect of ovarian hormones on survival genes in laser captured serotonin neurons from macaques. J Neurochem 2008, 105:1129-1143.
    • (2008) J Neurochem , vol.105 , pp. 1129-1143
    • Bethea, C.L.1    Reddy, A.P.2
  • 10
    • 38449103132 scopus 로고    scopus 로고
    • 5-HTT binding in recovered depressed patients and healthy volunteers: a positron emission tomography study with [11C]DASB
    • Bhagwagar Z., Murthy N., Selvaraj S., Hinz R., Taylor M., Fancy S., Grasby P., Cowen P. 5-HTT binding in recovered depressed patients and healthy volunteers: a positron emission tomography study with [11C]DASB. Am J Psychiatry 2007, 164:1858-1865.
    • (2007) Am J Psychiatry , vol.164 , pp. 1858-1865
    • Bhagwagar, Z.1    Murthy, N.2    Selvaraj, S.3    Hinz, R.4    Taylor, M.5    Fancy, S.6    Grasby, P.7    Cowen, P.8
  • 11
    • 2042542084 scopus 로고    scopus 로고
    • Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635
    • Bhagwagar Z., Rabiner E.A., Sargent P.A., Grasby P.M., Cowen P.J. Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635. Mol Psychiatry 2004, 9:386-392.
    • (2004) Mol Psychiatry , vol.9 , pp. 386-392
    • Bhagwagar, Z.1    Rabiner, E.A.2    Sargent, P.A.3    Grasby, P.M.4    Cowen, P.J.5
  • 12
    • 67349125852 scopus 로고    scopus 로고
    • Neuroprotective actions of sex steroids in Parkinson's disease
    • Bourque M., Dluzen D.E., Di Paolo T. Neuroprotective actions of sex steroids in Parkinson's disease. Front Neuroendocrinol 2009, 30:142-157.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 142-157
    • Bourque, M.1    Dluzen, D.E.2    Di Paolo, T.3
  • 13
    • 34748836926 scopus 로고    scopus 로고
    • Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder
    • Cannon D.M., Ichise M., Rollis D., Klaver J.M., Gandhi S.K., Charney D.S., Manji H.K., Drevets W.C. Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder. Biol Psychiatry 2007, 62:870-877.
    • (2007) Biol Psychiatry , vol.62 , pp. 870-877
    • Cannon, D.M.1    Ichise, M.2    Rollis, D.3    Klaver, J.M.4    Gandhi, S.K.5    Charney, D.S.6    Manji, H.K.7    Drevets, W.C.8
  • 15
    • 33947171448 scopus 로고    scopus 로고
    • Hypothalamic expression of serotonin 1A, 2A and 2C receptors and GAD67 in female cynomolgus monkeys with different sensitivity to stress
    • Centeno M.L., Sanchez R.L., Cameron J.L., Bethea C.L. Hypothalamic expression of serotonin 1A, 2A and 2C receptors and GAD67 in female cynomolgus monkeys with different sensitivity to stress. Brain Res 2007, 1142:1-12.
    • (2007) Brain Res , vol.1142 , pp. 1-12
    • Centeno, M.L.1    Sanchez, R.L.2    Cameron, J.L.3    Bethea, C.L.4
  • 16
    • 36248970604 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone and pro-opiomelanocortin gene expression in female monkeys with differences in sensitivity to stress
    • Centeno M.L., Sanchez R.L., Reddy A.P., Cameron J.L., Bethea C.L. Corticotropin-releasing hormone and pro-opiomelanocortin gene expression in female monkeys with differences in sensitivity to stress. Neuroendocrinology 2007, 86:277-288.
    • (2007) Neuroendocrinology , vol.86 , pp. 277-288
    • Centeno, M.L.1    Sanchez, R.L.2    Reddy, A.P.3    Cameron, J.L.4    Bethea, C.L.5
  • 21
    • 17344381830 scopus 로고    scopus 로고
    • Role of serotonin in sleep mechanisms
    • Dugovic C. Role of serotonin in sleep mechanisms. Rev Neurol (Paris) 2001, 157:S16-S19.
    • (2001) Rev Neurol (Paris) , vol.157
    • Dugovic, C.1
  • 22
    • 0016218168 scopus 로고
    • Male dominance and aggression in Japanese macaque reproduction
    • Eaton G.G. Male dominance and aggression in Japanese macaque reproduction. Adv Behav Biol 1974, 11:287-297.
    • (1974) Adv Behav Biol , vol.11 , pp. 287-297
    • Eaton, G.G.1
  • 23
    • 56149099978 scopus 로고    scopus 로고
    • Depression during menopausal transition: a review of treatment strategies and pathophysiological correlates
    • Frey B.N., Lord C., Soares C.N. Depression during menopausal transition: a review of treatment strategies and pathophysiological correlates. Menopause Int 2008, 14:123-128.
    • (2008) Menopause Int , vol.14 , pp. 123-128
    • Frey, B.N.1    Lord, C.2    Soares, C.N.3
  • 25
    • 0025001409 scopus 로고
    • Gonadal hormones and antihormones, serotonin and mood
    • Halbreich U. Gonadal hormones and antihormones, serotonin and mood. Psychopharmacol Bull 1990, 26(3):291-295.
    • (1990) Psychopharmacol Bull , vol.26 , Issue.3 , pp. 291-295
    • Halbreich, U.1
  • 27
    • 33748884025 scopus 로고    scopus 로고
    • A 10-year follow-up of postmenopausal women on long-term continuous combined hormone replacement therapy: update of safety and quality-of-life findings
    • Heikkinen J., Vaheri R., Timonen U. A 10-year follow-up of postmenopausal women on long-term continuous combined hormone replacement therapy: update of safety and quality-of-life findings. J Br Menopause Soc 2006, 12:115-125.
    • (2006) J Br Menopause Soc , vol.12 , pp. 115-125
    • Heikkinen, J.1    Vaheri, R.2    Timonen, U.3
  • 28
    • 0033492916 scopus 로고    scopus 로고
    • The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes
    • Hendricks T., Francis N., Fyodorov D., Deneris E.S. The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes. J Neurosci 1999, 19:10348-10356.
    • (1999) J Neurosci , vol.19 , pp. 10348-10356
    • Hendricks, T.1    Francis, N.2    Fyodorov, D.3    Deneris, E.S.4
  • 30
    • 78650794355 scopus 로고    scopus 로고
    • Sensitivity to stress-induced reproductive dysfunction is associated with a selective but not a generalized increase in activity of the adrenal axis
    • Herod S.M., Dettmer A.M., Novak M.A., Meyer J.S., Cameron J.L. Sensitivity to stress-induced reproductive dysfunction is associated with a selective but not a generalized increase in activity of the adrenal axis. Am J Physiol Endocrinol Metab 2011, 300:E28-E36.
    • (2011) Am J Physiol Endocrinol Metab , vol.300
    • Herod, S.M.1    Dettmer, A.M.2    Novak, M.A.3    Meyer, J.S.4    Cameron, J.L.5
  • 31
    • 78650786843 scopus 로고    scopus 로고
    • Treatment with a CRH-R1 antagonist prevents stress-induced suppression of the central neural drive to the reproductive axis in female macaques
    • Herod S.M., Pohl C.R., Cameron J.L. Treatment with a CRH-R1 antagonist prevents stress-induced suppression of the central neural drive to the reproductive axis in female macaques. Am J Physiol Endocrinol Metab 2011, 300:E19-E27.
    • (2011) Am J Physiol Endocrinol Metab , vol.300
    • Herod, S.M.1    Pohl, C.R.2    Cameron, J.L.3
  • 32
    • 33746257117 scopus 로고    scopus 로고
    • Estrogen selectively increases tryptophan hydroxylase-2 mRNA expression in distinct subregions of rat midbrain raphe nucleus: association between gene expression and anxiety behavior in the open field
    • Hiroi R., McDevitt R.A., Neumaier J.F. Estrogen selectively increases tryptophan hydroxylase-2 mRNA expression in distinct subregions of rat midbrain raphe nucleus: association between gene expression and anxiety behavior in the open field. Biol Psychiatry 2006, 60:288-295.
    • (2006) Biol Psychiatry , vol.60 , pp. 288-295
    • Hiroi, R.1    McDevitt, R.A.2    Neumaier, J.F.3
  • 33
    • 0027310916 scopus 로고
    • On neuronal health
    • Isacson O. On neuronal health. Trends Neurosci 1993, 16:306-308.
    • (1993) Trends Neurosci , vol.16 , pp. 306-308
    • Isacson, O.1
  • 34
    • 79952438213 scopus 로고    scopus 로고
    • Region-specific regulation of 5-HT1A receptor expression by Pet-1-dependent mechanisms in vivo
    • Jacobsen K.X., Czesak M., Deria M., Le François B., Albert P.R. Region-specific regulation of 5-HT1A receptor expression by Pet-1-dependent mechanisms in vivo. J Neurochem 2011, 116:1066-1076.
    • (2011) J Neurochem , vol.116 , pp. 1066-1076
    • Jacobsen, K.X.1    Czesak, M.2    Deria, M.3    Le François, B.4    Albert, P.R.5
  • 35
    • 0025959671 scopus 로고
    • Molecular biology of serotonin receptors
    • Julius D. Molecular biology of serotonin receptors. Annu Rev Neurosci 1991, 14:335-360.
    • (1991) Annu Rev Neurosci , vol.14 , pp. 335-360
    • Julius, D.1
  • 36
    • 67349245212 scopus 로고    scopus 로고
    • Impact of sex steroids on neuroinflammatory processes and experimental multiple sclerosis
    • Kipp M., Beyer C. Impact of sex steroids on neuroinflammatory processes and experimental multiple sclerosis. Front Neuroendocrinol 2009, 30:188-200.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 188-200
    • Kipp, M.1    Beyer, C.2
  • 37
    • 58149383261 scopus 로고    scopus 로고
    • Serotonergic transcription of human FEV reveals direct GATA factor interactions and fate of Pet-1-deficient serotonin neuron precursors
    • Krueger K.C., Deneris E.S. Serotonergic transcription of human FEV reveals direct GATA factor interactions and fate of Pet-1-deficient serotonin neuron precursors. J Neurosci 2008, 28:12748-12758.
    • (2008) J Neurosci , vol.28 , pp. 12748-12758
    • Krueger, K.C.1    Deneris, E.S.2
  • 38
    • 0032706095 scopus 로고    scopus 로고
    • Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice
    • Li Q., Wichems C., Heils A., Van De Kar L.D., Lesch K.P., Murphy D.L. Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice. J Pharmacol Exp Ther 1999, 291:999-1007.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 999-1007
    • Li, Q.1    Wichems, C.2    Heils, A.3    Van De Kar, L.D.4    Lesch, K.P.5    Murphy, D.L.6
  • 39
    • 77952886325 scopus 로고    scopus 로고
    • Ovarian steroids decrease DNA fragmentation in the serotonin neurons of non-injured rhesus macaques
    • Lima F.B., Bethea C.L. Ovarian steroids decrease DNA fragmentation in the serotonin neurons of non-injured rhesus macaques. Mol Psychiatry 2010, 15:657-668.
    • (2010) Mol Psychiatry , vol.15 , pp. 657-668
    • Lima, F.B.1    Bethea, C.L.2
  • 40
    • 70349738104 scopus 로고    scopus 로고
    • Stress sensitive female macaques have decreased fifth Ewing variant (Fev) and serotonin-related gene expression that is not reversed by citalopram
    • Lima F.B., Centeno M.L., Costa M.E., Reddy A.P., Cameron J.L., Bethea C.L. Stress sensitive female macaques have decreased fifth Ewing variant (Fev) and serotonin-related gene expression that is not reversed by citalopram. Neuroscience 2009, 164:676-691.
    • (2009) Neuroscience , vol.164 , pp. 676-691
    • Lima, F.B.1    Centeno, M.L.2    Costa, M.E.3    Reddy, A.P.4    Cameron, J.L.5    Bethea, C.L.6
  • 41
    • 33744993204 scopus 로고    scopus 로고
    • Interactions between corticotropin-releasing hormone and serotonin: implications for the aetiology and treatment of anxiety disorders
    • Linthorst A.C. Interactions between corticotropin-releasing hormone and serotonin: implications for the aetiology and treatment of anxiety disorders. Handb Exp Pharmacol 2005, 181-204.
    • (2005) Handb Exp Pharmacol , pp. 181-204
    • Linthorst, A.C.1
  • 42
    • 77957285177 scopus 로고    scopus 로고
    • Pet-1 is required across different stages of life to regulate serotonergic function
    • Liu C., Maejima T., Wyler S.C., Casadesus G., Herlitze S., Deneris E.S. Pet-1 is required across different stages of life to regulate serotonergic function. Nat Neurosci 2010, 13:1190-1198.
    • (2010) Nat Neurosci , vol.13 , pp. 1190-1198
    • Liu, C.1    Maejima, T.2    Wyler, S.C.3    Casadesus, G.4    Herlitze, S.5    Deneris, E.S.6
  • 43
    • 0036279353 scopus 로고    scopus 로고
    • Ovarian steroid regulation of 5HT1A receptor binding and G protein activation in female monkeys
    • Lu N.Z., Bethea C.L. Ovarian steroid regulation of 5HT1A receptor binding and G protein activation in female monkeys. Neuropsychopharmacology 2002, 27:12-24.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 12-24
    • Lu, N.Z.1    Bethea, C.L.2
  • 44
    • 0038143608 scopus 로고    scopus 로고
    • Ovarian steroid regulation of serotonin reuptake transporter (SERT) binding, distribution, and function in female macaques
    • Lu N.Z., Eshleman A.J., Janowsky A., Bethea C.L. Ovarian steroid regulation of serotonin reuptake transporter (SERT) binding, distribution, and function in female macaques. Mol Psychiatry 2003, 8:353-360.
    • (2003) Mol Psychiatry , vol.8 , pp. 353-360
    • Lu, N.Z.1    Eshleman, A.J.2    Janowsky, A.3    Bethea, C.L.4
  • 45
    • 19844365569 scopus 로고    scopus 로고
    • Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor
    • Maier S.F., Watkins L.R. Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor. Neurosci Biobehav Rev 2005, 29:829-841.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 829-841
    • Maier, S.F.1    Watkins, L.R.2
  • 47
    • 0000845242 scopus 로고
    • An ecological study of troop fissions of Japanese monkeys (Macaca fuscata yaku) on Yakushima Island, Japan
    • Maruhashi T. An ecological study of troop fissions of Japanese monkeys (Macaca fuscata yaku) on Yakushima Island, Japan. Primates 1982, 23:317-337.
    • (1982) Primates , vol.23 , pp. 317-337
    • Maruhashi, T.1
  • 48
    • 50249099851 scopus 로고    scopus 로고
    • The effects of experimentally lowered serotonin function on emotional information processing and memory in remitted depressed patients
    • Merens W., Booij L., Haffmans P.M., Van der Does A.J. The effects of experimentally lowered serotonin function on emotional information processing and memory in remitted depressed patients. J Psychopharmacol 2008, 22:653-662.
    • (2008) J Psychopharmacol , vol.22 , pp. 653-662
    • Merens, W.1    Booij, L.2    Haffmans, P.M.3    Van der Does, A.J.4
  • 49
    • 34247137134 scopus 로고    scopus 로고
    • Imaging the serotonin transporter during major depressive disorder and antidepressant treatment
    • Meyer J.H. Imaging the serotonin transporter during major depressive disorder and antidepressant treatment. J Psychiatry Neurosci 2007, 32:86-102.
    • (2007) J Psychiatry Neurosci , vol.32 , pp. 86-102
    • Meyer, J.H.1
  • 50
    • 7044245978 scopus 로고    scopus 로고
    • Tamoxifen fails to affect central serotonergic tone but increases indices of anxiety in female rhesus macaques
    • Mook D., Felger J., Graves F., Wallen K., Wilson M.E. Tamoxifen fails to affect central serotonergic tone but increases indices of anxiety in female rhesus macaques. Psychoneuroendocrinology 2005, 30:273-283.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 273-283
    • Mook, D.1    Felger, J.2    Graves, F.3    Wallen, K.4    Wilson, M.E.5
  • 52
    • 0842334508 scopus 로고    scopus 로고
    • Low central nervous system serotonergic responsivity is associated with the metabolic syndrome and physical inactivity
    • Muldoon M.F., Mackey R.H., Williams K.V., Korytkowski M.T., Flory J.D., Manuck S.B. Low central nervous system serotonergic responsivity is associated with the metabolic syndrome and physical inactivity. J Clin Endocrinol Metab 2004, 89:266-271.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 266-271
    • Muldoon, M.F.1    Mackey, R.H.2    Williams, K.V.3    Korytkowski, M.T.4    Flory, J.D.5    Manuck, S.B.6
  • 53
    • 62349131315 scopus 로고    scopus 로고
    • DNA repair in mammalian cells: nucleotide excision repair: variations on versatility
    • Nouspikel T. DNA repair in mammalian cells: nucleotide excision repair: variations on versatility. Cell Mol Life Sci 2009, 66:994-1009.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 994-1009
    • Nouspikel, T.1
  • 54
    • 0033961277 scopus 로고    scopus 로고
    • Terminally differentiated human neurons repair transcribed genes but display attenuated global DNA repair and modulation of repair gene expression
    • Nouspikel T., Hanawalt P.C. Terminally differentiated human neurons repair transcribed genes but display attenuated global DNA repair and modulation of repair gene expression. Mol Cell Biol 2000, 20:1562-1570.
    • (2000) Mol Cell Biol , vol.20 , pp. 1562-1570
    • Nouspikel, T.1    Hanawalt, P.C.2
  • 55
    • 0036012794 scopus 로고    scopus 로고
    • DNA repair in terminally differentiated cells
    • Nouspikel T., Hanawalt P.C. DNA repair in terminally differentiated cells. DNA Repair (Amst) 2002, 1:59-75.
    • (2002) DNA Repair (Amst) , vol.1 , pp. 59-75
    • Nouspikel, T.1    Hanawalt, P.C.2
  • 57
    • 0033105944 scopus 로고    scopus 로고
    • Ovarian steroid regulation of 5HT1A autoreceptor messenger ribonucleic acid expression in the dorsal raphe of rhesus macaques
    • Pecins-Thompson M., Bethea C.L. Ovarian steroid regulation of 5HT1A autoreceptor messenger ribonucleic acid expression in the dorsal raphe of rhesus macaques. Neuroscience 1998, 89:267-277.
    • (1998) Neuroscience , vol.89 , pp. 267-277
    • Pecins-Thompson, M.1    Bethea, C.L.2
  • 58
    • 0031932036 scopus 로고    scopus 로고
    • Regulation of serotonin re-uptake transporter mRNA expression by ovarian steroids in rhesus macaques
    • Pecins-Thompson M., Brown N.A., Bethea C.L. Regulation of serotonin re-uptake transporter mRNA expression by ovarian steroids in rhesus macaques. Mol Brain Res 1998, 53:120-129.
    • (1998) Mol Brain Res , vol.53 , pp. 120-129
    • Pecins-Thompson, M.1    Brown, N.A.2    Bethea, C.L.3
  • 61
    • 0022831907 scopus 로고
    • Seasonality of adult male Japanese macaques (Macaca fuscata): androgens and behavior in a confined troop
    • Rostal D.C., Glick B.B., Eaton G.G., Resko J.A. Seasonality of adult male Japanese macaques (Macaca fuscata): androgens and behavior in a confined troop. Horm Behav 1986, 20:452-462.
    • (1986) Horm Behav , vol.20 , pp. 452-462
    • Rostal, D.C.1    Glick, B.B.2    Eaton, G.G.3    Resko, J.A.4
  • 62
    • 18044381746 scopus 로고    scopus 로고
    • A second tryptophan hydroxylase isoform, TPH-2 mRNA, is increased by ovarian steroids in the raphe region of macaques
    • Sanchez R.L., Reddy A.P., Centeno M.L., Henderson J.A., Bethea C.L. A second tryptophan hydroxylase isoform, TPH-2 mRNA, is increased by ovarian steroids in the raphe region of macaques. Mol Brain Res 2005, 135:194-203.
    • (2005) Mol Brain Res , vol.135 , pp. 194-203
    • Sanchez, R.L.1    Reddy, A.P.2    Centeno, M.L.3    Henderson, J.A.4    Bethea, C.L.5
  • 63
    • 65049083026 scopus 로고    scopus 로고
    • 5-HT(1A) receptor function in major depressive disorder
    • Savitz J., Lucki I., Drevets W.C. 5-HT(1A) receptor function in major depressive disorder. Prog Neurobiol 2009, 88:17-31.
    • (2009) Prog Neurobiol , vol.88 , pp. 17-31
    • Savitz, J.1    Lucki, I.2    Drevets, W.C.3
  • 64
    • 67349108331 scopus 로고    scopus 로고
    • Role of protein phosphatases and mitochondria in the neuroprotective effects of estrogens
    • Simpkins J.W., Yi K.D., Yang S.H. Role of protein phosphatases and mitochondria in the neuroprotective effects of estrogens. Front Neuroendocrinol 2009, 30:93-105.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 93-105
    • Simpkins, J.W.1    Yi, K.D.2    Yang, S.H.3
  • 65
    • 8444243748 scopus 로고    scopus 로고
    • Effects of ovarian steroids and raloxifene on proteins that synthesize, transport, and degrade serotonin in the raphe region of macaques
    • Smith L.J., Henderson J.A., Abell C.W., Bethea C.L. Effects of ovarian steroids and raloxifene on proteins that synthesize, transport, and degrade serotonin in the raphe region of macaques. Neuropsychopharmacology 2004, 29:2035-2045.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 2035-2045
    • Smith, L.J.1    Henderson, J.A.2    Abell, C.W.3    Bethea, C.L.4
  • 66
    • 67349251253 scopus 로고    scopus 로고
    • Neuroprotective effects of estrogens following ischemic stroke
    • Suzuki S., Brown C.M., Wise P.M. Neuroprotective effects of estrogens following ischemic stroke. Front Neuroendocrinol 2009, 30:201-211.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 201-211
    • Suzuki, S.1    Brown, C.M.2    Wise, P.M.3
  • 67
    • 45749099692 scopus 로고    scopus 로고
    • Depression and anxiety through the climacteric period: an epidemiological study (HUNT-II)
    • Tangen T., Mykletun A. Depression and anxiety through the climacteric period: an epidemiological study (HUNT-II). J Psychosom Obstet Gynaecol 2008, 29:125-131.
    • (2008) J Psychosom Obstet Gynaecol , vol.29 , pp. 125-131
    • Tangen, T.1    Mykletun, A.2
  • 68
    • 46549084347 scopus 로고    scopus 로고
    • Neuroprotective actions of ovarian hormones without insult in the raphe region of rhesus macaques
    • Tokuyama Y., Reddy A.P., Bethea C.L. Neuroprotective actions of ovarian hormones without insult in the raphe region of rhesus macaques. Neuroscience 2008, 154:720-731.
    • (2008) Neuroscience , vol.154 , pp. 720-731
    • Tokuyama, Y.1    Reddy, A.P.2    Bethea, C.L.3
  • 69
    • 0035872214 scopus 로고    scopus 로고
    • 5-HT2A receptors stimulate ACTH, corticosterone, oxytocin, renin, and prolactin release and activate hypothalamic CRF and oxytocin-expressing cells
    • Van de Kar L.D., Javed A., Zhang Y., Serres F., Raap D.K., Gray T.S. 5-HT2A receptors stimulate ACTH, corticosterone, oxytocin, renin, and prolactin release and activate hypothalamic CRF and oxytocin-expressing cells. J Neurosci 2001, 21:3572-3579.
    • (2001) J Neurosci , vol.21 , pp. 3572-3579
    • Van de Kar, L.D.1    Javed, A.2    Zhang, Y.3    Serres, F.4    Raap, D.K.5    Gray, T.S.6
  • 70
    • 78649903383 scopus 로고    scopus 로고
    • Interactions of corticotropin-releasing factor, urocortin and citalopram in a primate model of stress-induced amenorrhea
    • Weissheimer K.V., Herod S.M., Cameron J.L., Bethea C.L. Interactions of corticotropin-releasing factor, urocortin and citalopram in a primate model of stress-induced amenorrhea. Neuroendocrinology 2010, 92:224-234.
    • (2010) Neuroendocrinology , vol.92 , pp. 224-234
    • Weissheimer, K.V.1    Herod, S.M.2    Cameron, J.L.3    Bethea, C.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.