-
1
-
-
43549108142
-
Glucolipotoxicity: fuel excess and beta-cell dysfunction
-
Poitout V., Robertson R.P. Glucolipotoxicity: fuel excess and beta-cell dysfunction. Endocrine Rev. 2008, 29:351-366.
-
(2008)
Endocrine Rev.
, vol.29
, pp. 351-366
-
-
Poitout, V.1
Robertson, R.P.2
-
2
-
-
0036153256
-
Minireview: secondary beta-cell failure in type 2 diabetes - a convergence of glucotoxicity and lipotoxicity
-
Poitout V., Robertson R.P. Minireview: secondary beta-cell failure in type 2 diabetes - a convergence of glucotoxicity and lipotoxicity. Endocrinology 2002, 143:339-342.
-
(2002)
Endocrinology
, vol.143
, pp. 339-342
-
-
Poitout, V.1
Robertson, R.P.2
-
3
-
-
33745244769
-
A protective role for heme oxygenase-1 in INS-1 cells and rat islets that are exposed to high glucose conditions
-
Won K.C., Moon J.S., Eun M.J., Yoon J.S., Chun K.A., Cho I.H., Kim Y.W., Lee H.W. A protective role for heme oxygenase-1 in INS-1 cells and rat islets that are exposed to high glucose conditions. J. Korean Med. Sci. 2006, 21:418-424.
-
(2006)
J. Korean Med. Sci.
, vol.21
, pp. 418-424
-
-
Won, K.C.1
Moon, J.S.2
Eun, M.J.3
Yoon, J.S.4
Chun, K.A.5
Cho, I.H.6
Kim, Y.W.7
Lee, H.W.8
-
4
-
-
0029151863
-
Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: genetic and clinical implications
-
Unger R.H. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: genetic and clinical implications. Diabetes 1995, 44:863-870.
-
(1995)
Diabetes
, vol.44
, pp. 863-870
-
-
Unger, R.H.1
-
5
-
-
0032898667
-
Fatty acids, lipotoxicity and insulin secretion
-
McGarry J.D., Dobbins R.L. Fatty acids, lipotoxicity and insulin secretion. Diabetologia 1999, 42:128-138.
-
(1999)
Diabetologia
, vol.42
, pp. 128-138
-
-
McGarry, J.D.1
Dobbins, R.L.2
-
6
-
-
66349126859
-
Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways
-
Goldberg I.J., Eckel R.H., Abumrad N.A. Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways. J. Lipid Res. 2009, 50(Suppl.):86-90.
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
, pp. 86-90
-
-
Goldberg, I.J.1
Eckel, R.H.2
Abumrad, N.A.3
-
7
-
-
12744274513
-
Fatty acid translocase (CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion
-
Noushmehr H., D'Amico E., Farilla L., Hui H., Wawrowsky K.A., Mlynarski W., Doria A., Abumrad N.A., Perfetti R. Fatty acid translocase (CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion. Diabetes 2005, 54:472-481.
-
(2005)
Diabetes
, vol.54
, pp. 472-481
-
-
Noushmehr, H.1
D'Amico, E.2
Farilla, L.3
Hui, H.4
Wawrowsky, K.A.5
Mlynarski, W.6
Doria, A.7
Abumrad, N.A.8
Perfetti, R.9
-
8
-
-
73749085921
-
Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation
-
Wallin T., Ma Z., Ogata H., Jørgensen I.H., Iezzi M., Wang H., Wollheim C.B., Björklund A. Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation. Biochim. Biophys. Acta 2010, 1801:191-197.
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 191-197
-
-
Wallin, T.1
Ma, Z.2
Ogata, H.3
Jørgensen, I.H.4
Iezzi, M.5
Wang, H.6
Wollheim, C.B.7
Björklund, A.8
-
9
-
-
57349148153
-
Modulation of intestinal cholesterol absorption by high glucose levels: impact on cholesterol transporters, regulatory enzymes, and transcription factors
-
Ravid Z., Bendayan M., Delvin E., Sane A.T., Elchebly M., Lafond J., Lambert M., Mailhot G., Levy E. Modulation of intestinal cholesterol absorption by high glucose levels: impact on cholesterol transporters, regulatory enzymes, and transcription factors. Am. J. Physiol. Gastrointest. Liver Physiol. 2008, 295:873-885.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.295
, pp. 873-885
-
-
Ravid, Z.1
Bendayan, M.2
Delvin, E.3
Sane, A.T.4
Elchebly, M.5
Lafond, J.6
Lambert, M.7
Mailhot, G.8
Levy, E.9
-
10
-
-
0034033180
-
Inhibition of insulin gene expression by long-term exposure of pancreatic beta-cells to palmitate is dependent upon the presence of a stimulatory glucose concentration
-
Jacqueminet S., Briaud I., Rouault C., Reach G., Poitout V. Inhibition of insulin gene expression by long-term exposure of pancreatic beta-cells to palmitate is dependent upon the presence of a stimulatory glucose concentration. Metabolism 2000, 49:532-536.
-
(2000)
Metabolism
, vol.49
, pp. 532-536
-
-
Jacqueminet, S.1
Briaud, I.2
Rouault, C.3
Reach, G.4
Poitout, V.5
-
11
-
-
0030731946
-
Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels
-
Gremlich S., Bonny C., Waeber G., Thorens B. Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels. J. Biol. Chem. 1997, 272:30261-30269.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30261-30269
-
-
Gremlich, S.1
Bonny, C.2
Waeber, G.3
Thorens, B.4
-
12
-
-
0033304970
-
Glucose-induced preproinsulin gene expression is inhibited by the free-fatty acid palmitate
-
Ritz-Laser B., Meda P., Constant I., Klages N., Charollais A., Morales A., Magnan C., Ktorza A., Philippe J. Glucose-induced preproinsulin gene expression is inhibited by the free-fatty acid palmitate. Endocrinology 1999, 140:4005-4014.
-
(1999)
Endocrinology
, vol.140
, pp. 4005-4014
-
-
Ritz-Laser, B.1
Meda, P.2
Constant, I.3
Klages, N.4
Charollais, A.5
Morales, A.6
Magnan, C.7
Ktorza, A.8
Philippe, J.9
-
13
-
-
70349929485
-
Noninvasive quantification of pancreatic fat in humans
-
Lingvay I., Esser V., Legendre J.L., Price A.L., Wertz K.M., Adams-Huet B., Zhang S., Unger R.H., Szczepaniak L.S. Noninvasive quantification of pancreatic fat in humans. J. Clin. Endocrinol. Metab. 2009, 94:4070-4076.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 4070-4076
-
-
Lingvay, I.1
Esser, V.2
Legendre, J.L.3
Price, A.L.4
Wertz, K.M.5
Adams-Huet, B.6
Zhang, S.7
Unger, R.H.8
Szczepaniak, L.S.9
-
14
-
-
36049000864
-
Pancreatic fat content and beta-cell function in men with and without type 2 diabetes
-
Tushuizen M.E., Bunck M.C., Pouwels P.J., Bontemps S., van Waesberghe J.H., Schindhelm R.K., Mari A., Heine R.J., Diamant M. Pancreatic fat content and beta-cell function in men with and without type 2 diabetes. Diabetes Care 2007, 30:2916-2921.
-
(2007)
Diabetes Care
, vol.30
, pp. 2916-2921
-
-
Tushuizen, M.E.1
Bunck, M.C.2
Pouwels, P.J.3
Bontemps, S.4
van Waesberghe, J.H.5
Schindhelm, R.K.6
Mari, A.7
Heine, R.J.8
Diamant, M.9
-
15
-
-
0842284799
-
Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
-
Robertson R.P., Harmon J., Tran P.O., Poitout V. Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes. Diabetes 2004, 53(Suppl. 1):S119-S124.
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Robertson, R.P.1
Harmon, J.2
Tran, P.O.3
Poitout, V.4
-
16
-
-
84862809326
-
Glucolipotoxicity in pancreatic β-cells
-
Kim J.W., Yoon K.H. Glucolipotoxicity in pancreatic β-cells. Diabetes Metab. J. 2011, 35:444-450.
-
(2011)
Diabetes Metab. J.
, vol.35
, pp. 444-450
-
-
Kim, J.W.1
Yoon, K.H.2
-
17
-
-
0029046673
-
Effects of a 48-h fat infusion on insulin secretion and glucose utilization
-
Boden G., Chen X., Rosner J., Barton M. Effects of a 48-h fat infusion on insulin secretion and glucose utilization. Diabetes 1995, 44:1239-1242.
-
(1995)
Diabetes
, vol.44
, pp. 1239-1242
-
-
Boden, G.1
Chen, X.2
Rosner, J.3
Barton, M.4
-
18
-
-
17944367197
-
Glucose-induced insulin hypersecretion in lipid-infused healthy subjects is associated with a decrease in plasma norepinephrine concentration and urinary excretion
-
Magnan C., Cruciani C., Clement L., et al. Glucose-induced insulin hypersecretion in lipid-infused healthy subjects is associated with a decrease in plasma norepinephrine concentration and urinary excretion. J. Clin. Endocrinol. Metab. 2001, 86:4901-4907.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 4901-4907
-
-
Magnan, C.1
Cruciani, C.2
Clement, L.3
-
19
-
-
0141755328
-
A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes
-
Kashyap S., Belfort R., Gastaldelli A., et al. A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes. Diabetes 2003, 52:2461-2474.
-
(2003)
Diabetes
, vol.52
, pp. 2461-2474
-
-
Kashyap, S.1
Belfort, R.2
Gastaldelli, A.3
-
20
-
-
0029049346
-
A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM
-
Paolisso G., Tataranni P.A., Foley J.E., Bogardus C., Howard B.V., Ravussin E. A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM. Diabetologia 1995, 38(10):1213-1217.
-
(1995)
Diabetologia
, vol.38
, Issue.10
, pp. 1213-1217
-
-
Paolisso, G.1
Tataranni, P.A.2
Foley, J.E.3
Bogardus, C.4
Howard, B.V.5
Ravussin, E.6
-
21
-
-
1542285102
-
Prolonged increase of plasma nonesterified fatty acids fully abolishes the stimulatory effect of 24h of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men
-
Leung N., Sakaue T., Carpentier A., et al. Prolonged increase of plasma nonesterified fatty acids fully abolishes the stimulatory effect of 24h of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men. Diabetologia 2004, 47:204-213.
-
(2004)
Diabetologia
, vol.47
, pp. 204-213
-
-
Leung, N.1
Sakaue, T.2
Carpentier, A.3
-
22
-
-
0034005968
-
Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes
-
Carpentier A., Mittelman S.D., Bergman R.N., et al. Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes 2000, 49:399-408.
-
(2000)
Diabetes
, vol.49
, pp. 399-408
-
-
Carpentier, A.1
Mittelman, S.D.2
Bergman, R.N.3
-
23
-
-
36649012405
-
Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, nondiabetic men
-
Xiao C., Giacca A., Lewis G.F. Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, nondiabetic men. Diabetologia 2008, 51:139-146.
-
(2008)
Diabetologia
, vol.51
, pp. 139-146
-
-
Xiao, C.1
Giacca, A.2
Lewis, G.F.3
-
24
-
-
0033009463
-
Effects of fatty acids and ketone bodies on basal insulin secretion in type 2 diabetes
-
Boden G., Chen X. Effects of fatty acids and ketone bodies on basal insulin secretion in type 2 diabetes. Diabetes 1999, 48:577-583.
-
(1999)
Diabetes
, vol.48
, pp. 577-583
-
-
Boden, G.1
Chen, X.2
-
25
-
-
79251585927
-
Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies
-
Giacca A., Xiao C., Oprescu A.I., Carpentier A.C., Lewis G.F. Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies. Am. J. Physiol. Endocrinol. Metab. 2011, 300(2):E255-E262.
-
(2011)
Am. J. Physiol. Endocrinol. Metab.
, vol.300
, Issue.2
-
-
Giacca, A.1
Xiao, C.2
Oprescu, A.I.3
Carpentier, A.C.4
Lewis, G.F.5
-
26
-
-
79951705814
-
Ectopic fat storage in the pancreas, liver, and abdominal fat depots: impact on β-cell function in individuals with impaired glucose metabolism
-
Epub 2010 Nov 17
-
van der Zijl N.J., Goossens G.H., Moors C.C., van Raalte D.H., Muskiet M.H., Pouwels P.J., Blaak E.E., Diamant M. Ectopic fat storage in the pancreas, liver, and abdominal fat depots: impact on β-cell function in individuals with impaired glucose metabolism. J. Clin. Endocrinol. Metab. 2011, 96(2):459-467. Epub 2010 Nov 17.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, Issue.2
, pp. 459-467
-
-
van der Zijl, N.J.1
Goossens, G.H.2
Moors, C.C.3
van Raalte, D.H.4
Muskiet, M.H.5
Pouwels, P.J.6
Blaak, E.E.7
Diamant, M.8
-
27
-
-
33748588135
-
The role of hyperglycemia in FAT/CD36 expression and function
-
Epub 2006 Jul 13
-
Chen M., Yang Y.K., Loux T.J., Georgeson K.E., Harmon C.M. The role of hyperglycemia in FAT/CD36 expression and function. Pediatr. Surg. Int. 2006, 22(8):647-654. Epub 2006 Jul 13.
-
(2006)
Pediatr. Surg. Int.
, vol.22
, Issue.8
, pp. 647-654
-
-
Chen, M.1
Yang, Y.K.2
Loux, T.J.3
Georgeson, K.E.4
Harmon, C.M.5
-
28
-
-
77949412179
-
High glucose promotes intracellular lipid accumulation in vascular smooth muscle cells by impairing cholesterol influx and efflux balance
-
Epub 2009 Dec 10
-
Xue J.H., Yuan Z., Wu Y., Liu Y., Zhao Y., Zhang W.P., Tian Y.L., Liu W.M., Liu Y., Kishimoto C. High glucose promotes intracellular lipid accumulation in vascular smooth muscle cells by impairing cholesterol influx and efflux balance. Cardiovasc. Res. 2010, 86(1):141-150. Epub 2009 Dec 10.
-
(2010)
Cardiovasc. Res.
, vol.86
, Issue.1
, pp. 141-150
-
-
Xue, J.H.1
Yuan, Z.2
Wu, Y.3
Liu, Y.4
Zhao, Y.5
Zhang, W.P.6
Tian, Y.L.7
Liu, W.M.8
Liu, Y.9
Kishimoto, C.10
-
29
-
-
79959723668
-
Suppression of FAT/CD36 mRNA by human growth hormone in pancreatic β-cells
-
Epub 2011 Jun 7
-
Dalgaard L.T., Thams P., Gaarn L.W., Jensen J., Lee Y.C., Nielsen J.H. Suppression of FAT/CD36 mRNA by human growth hormone in pancreatic β-cells. Biochem. Biophys. Res. Commun. 2011, 410(2):345-350. Epub 2011 Jun 7.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.410
, Issue.2
, pp. 345-350
-
-
Dalgaard, L.T.1
Thams, P.2
Gaarn, L.W.3
Jensen, J.4
Lee, Y.C.5
Nielsen, J.H.6
-
30
-
-
12744274513
-
Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion
-
Noushmehr H., D'Amico E., Farilla L., Hui H., Wawrowsky K.A., Mlynarski W., Doria A., Abumrad N.A., Perfetti R. Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion. Diabetes 2005, 54(2):472-481.
-
(2005)
Diabetes
, vol.54
, Issue.2
, pp. 472-481
-
-
Noushmehr, H.1
D'Amico, E.2
Farilla, L.3
Hui, H.4
Wawrowsky, K.A.5
Mlynarski, W.6
Doria, A.7
Abumrad, N.A.8
Perfetti, R.9
|