Geranylgeranylacetone protects mice against morphine-induced hyperlocomotion, rewarding effect, and withdrawal syndrome

Free Radical Biology and Medicine

Volumn 52, Issue 7, 2012, Pages 1218-1227

  Luo, Fu Cheng ^a   Qi, Lei ^a   Lv, Tao ^a   Wang, Sheng Dong ^a   Liu, Hua ^b   Nakamura, Hajime ^c   Yodoi, Junji ^d   Bai, Jie ^a  

^a KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b FIRST PEOPLE S HOSPITAL OF YUNNAN PROVINCE   (China)

^c Kitano Hospital   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

Free radicals; Geranylgeranylacetone; Heat shock protein 70; Morphine; Thioredoxin 1

Indexed keywords

CYCLIC AMP; CYCLIN DEPENDENT KINASE 5; HEAT SHOCK PROTEIN 70; MORPHINE; NALOXONE; TEPRENONE; THIOREDOXIN 1; TRANSCRIPTION FACTOR FOSB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; FRONTAL CORTEX; HIPPOCAMPUS; HYPERLOCOMOTION; JUMPING; LIMB TREMOR; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REARING; REWARD; VENTRAL TEGMENTUM; WITHDRAWAL SYNDROME;

ANALGESICS, OPIOID; ANIMALS; BLOTTING, WESTERN; BRAIN; CELL MOVEMENT; DITERPENES; HSP70 HEAT-SHOCK PROTEINS; MICE; MICE, INBRED C57BL; MORPHINE; MORPHINE DEPENDENCE; REWARD; SUBSTANCE WITHDRAWAL SYNDROME; THIOREDOXINS;

MUS;

EID: 84862817006     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.01.004     Document Type: Article

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