The effects of metabotropic glutamate receptor 7 allosteric agonist N,N'-dibenzhydrylethane-1,2-diamine dihydrochloride on developmental sevoflurane neurotoxicity: Role of extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase signaling pathway

Neuroscience

Volumn 205, Issue , 2012, Pages 167-177

  Wang, W Y ^a   Wang, H ^a   Luo, Y ^a   Jia, L J ^a   Zhao, J N ^b   Zhang, H H ^a   Ma, Z W ^a   Xue, Q S ^a   Yu, B W ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Hippocampus; Learning and memory; MAPK; MGluRs; Neurotoxicity; Sevoflurane

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; ALPHA METHYLSERINE O PHOSPHATE; AMN 082; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CIS 2 [[(3,5 DICHLOROPHENYL)AMINO]CARBONYL]CYCLOHEXANECARBOXYLIC ACID; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 4; METABOTROPIC RECEPTOR 7; METABOTROPIC RECEPTOR AGONIST; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N,N' DIBENZHYDRYLETHANE 1,2 DIAMINE; NEUROPROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; SEVOFLURANE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VU 0155041;

ALLOSTERISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; EMBRYO; ENZYME INHIBITION; ENZYME REPRESSION; FLOW CYTOMETRY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; LEARNING DISORDER; LONG TERM EXPOSURE; MAZE TEST; MEMORY DISORDER; MENTAL PERFORMANCE; NEUROPROTECTION; NEUROTOXICITY; NICK END LABELING; NONHUMAN; OPEN FIELD BEHAVIOR; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TREATMENT DURATION; WESTERN BLOTTING;

ALLOSTERIC REGULATION; ANESTHETICS, INHALATION; ANIMALS; ANIMALS, NEWBORN; BENZHYDRYL COMPOUNDS; EXCITATORY AMINO ACID AGONISTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MAP KINASE SIGNALING SYSTEM; METHYL ETHERS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROPROTECTIVE AGENTS; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 84862816912     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.12.039     Document Type: Article

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