ERK1/2 Activation Is Necessary for BDNF to Increase Dendritic Spine Density in Hippocampal CA1 Pyramidal Neurons

Learning and Memory

Volumn 11, Issue 2, 2004, Pages 172-178

  Alonso, Mariana ^a,b   Medina, Jorge H ^a   Pozzo Miller, Lucas ^b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BRAIN DERIVED NEUROTROPHIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NEUROTROPHIN; YELLOW FLUORESCENT PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; DENDRITIC SPINE; DENSITY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE TRANSFER; HIPPOCAMPUS; LASER MICROSCOPY; LEARNING; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; RAT; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; TISSUE CULTURE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DENDRITIC SPINES; ENZYME ACTIVATION; HIPPOCAMPUS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURONAL PLASTICITY; ORGAN CULTURE TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 1842579578     PISSN: 10720502     EISSN: None     Source Type: Journal    
DOI: 10.1101/lm.67804     Document Type: Article

References (43)

1. Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T., and Saltiel, A.R. 1995. PD098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270: 27489-27494.
2. Alonso, M., Vianna, M.R.M., Depino, A.M., Mello e Souza, T., Pereira, P., Szapiro, G., Viola, H., Pitossi, F., Izquierdo, I., and Medina, J.H. 2002a. BNDF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus 12: 551-560.
3. Alonso, M., Vianna, M.R.M., Izquierdo, I., and Medina, J.H. 2002b. Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus. Cell. Mol. Neurobiol. 22: 647-658.
4. Blanquet, P.R. 2000. Identification of two persistently activated neurotrophin-regulated pathways in rat hippocampus. Neuroscience 95: 705-719.
5. Cavanaugh, J.E., Ham, J., Hetman, M., Poser, S., Yang, C., and Xia, Z. 2001, Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons. J. Neurosci. 21: 434-443.
6. Danzer, S.C., Crooks, K.R.C., Lo, D.C., and McNamara, J.O. 2002. Increased expression of brain-derived neurotrophic factor induces formation of basal dendrites and axonal branching in dentate granule cells in hippocampal explants cultures. J. Neurosci. 22: 9754-9763.
7. Favata, M.F., Horiuchi, K.Y., Manos, E.J., Daulerio, A.J., Stradley, D.A., Feeser, W.S., Van Dyk, D.E., Pitts, W.J., Earl, R.A., Hobbs, F., et al. 1998. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273: 18623-18632.
8. Finkbeiner, S., Tavazoie, S., Maloratsky, A., Jacobs, K., Harris, K., and Greenberg, M. 1997. CREB: A major mediator of neuronal neurotrophin responses. Neuron 19: 1031-1047.
9. Gähwiler, B.H. 1981. Organotypic monolayer cultures of nervous tissue. J. Neurosci. Meth. 4: 329-342.
10. Gottschalk, W.A., Jiang, H., Tartaglia, N., Feng, L., Figurov, A., and Lu, B. 1999. Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus. Learn Mem. 6: 243-256.
11. Horch, H.W. and Katz, L.C. 2002. BDNF release from single cell elicits local dendritic growth in nearby neurons. Nat. Neurosci. 11: 1177-1184.
12. Horch, H.W., Kruttgen, A., Protbury, S.D., and Katz, L.C. 1999. Destabilization of cortical dendrites and spines by BDNF: Neuron 23: 353-364.
13. Kamakura, S., Moriguchi, T., and Nishida, E. 1999. Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. J. Biol. Chem. 274: 26563-26571.
14. Liu, L., Cavanaugh, J.E., Wang, Y., Sakagami, H., Mao, Z., and Xia, Z. 2003. ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons. Proc. Natl. Acad. Sci. 100: 8532-8537.
15. Lo, D.C., McAllister, A.K., and Katz, L.C. 1994. Neuronal transfection in brain slices using particle-mediated gene transfer. Neuron 13: 1263-1268.
16. Lonze, B.E. and Ginty, D.D. 2002. Function and regulation of CREB family transcription factors in the nervous system. Neuron 35: 605-623.
17. McAllister, A.K., Katz, L.C., and Lo, D.C. 1995. Neurotrophins regulate dendritic growth in developing visual cortex. Neuron 15: 791-803.
18. -. 1999. Neurotrophins and synaptic plasticity. Annu. Rev. Neurosci. 22: 295-318.
19. McCutchen, M.E., Bramham, C.R., and Pozzo-Miller, L.D. 2002. Modulation of neuronal calcium signaling by neurotrophic factors. Int. J. Dev. Neurosci. 20: 199-207.
20. Mertz, K., Koscheck, T., and Schilling, K. 2000. Brain-derived neurotrophic factor modulates dendritic morphology of cerebellar basket and stellate cells: An in vitro study. Neuroscience 97: 303-310.
21. Pizzorusso, T., Ratto, G.M., Putignano, E., and Maffei, L. 2000. Brain-derived neurotrophic factor causes cAMP response element-binding protein phosphorylation in absence of calcium increase in slices and cultured neurons from rat visual cortex. J. Neurosci. 20: 2809-2816.
22. Poo, M. 2001. Neurotrophins as synaptic modulators. Nat. Rev. Neurosci. 2: 24-32.
23. 2+ transients in spines of CA1 pyramidal neurons from hippocampal slices. J. Neurophysiol. 81: 1404-1411.
24. Schwartz, P.M., Borghesani, P.R., Levy, R.L., Pomeroy, S.L., and Segal, R.A. 1997. Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning. Neuron 19: 269-281.
25. Segal, R.A. and Greenberg, M.E. 1996. Intracellular signaling pathways activated by neurotrophic factor. Annu. Rev. Neurosci. 19: 463-489.
26. Shelton, D.L., Sutherland, J., Gripp, J., Camerato, T., Armanini, M.P., Phillips, H.S., Carroll, K., Spencer, S.D., and Levinson, A.D. 1995. Human trks: Molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins. J. Neurosci. 15: 477-491.
27. Shimada, A., Mason, C.A., and Morrison, M.E. 1998. TrkB signaling modulates spine density and morphology independent of dendrite structure in cultured neonatal Purkinje cells. J. Neurosci. 18: 8559-8570.
28. Sorra, K.E. and Harris, K.M. 2000. Overview on the structure, composition, function, development, and plasticity of hippocampal dendritic spines. Hippocampus 10: 501-511.
29. Stoppini, L., Buchs, P.A., and Muller, D. 1991. A simple method for organotypic cultures of nervous tissue. J. Neurosci. Meth. 37: 173-182.
30. Tartaglia, N., Du, J., Tyler, W.J., Neale, E., Pozzo-Miller, L., and Lu, B. 2001. Protein synthesis-dependent and -independent regulation of hippocampal synapses by brain-derived neurotrophic factor. J. Biol. Chem. 276: 37585-37593.
31. Tolwani, R.J., Buckmaster, P.S., Varma, S., Cosgaya, J.M., Wu, Y., Suri, C., and Shooter, E.M. 2002. BDNF overexpression increases dendrite complexity in hippocampal dentate gyrus. Neuroscience 3: 795-805.
32. Tyler, W.J. and Pozzo-Miller, L.D. 2001. BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses. J. Neurosci. 21: 4249-4258.
33. -. 2003. Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones. J. Physiol. 553: 497-509.
34. Tyler, W.J., Alonso, M., Bramham, C.R., and Pozzo-Miller, L.D. 2002a. From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn. Mem. 9: 224-237.
35. Tyler, W.J., Perrett, S., and Pozzo-Miller, L.D. 2002b. The role of neurotrophins in neurotransmitter release. Neuroscientist 8: 524-531.
36. Vicario-Abejon, C., Owens, D., McKay, R., and Segal, M. 2002. Role of neurotrophins in central synapse formation and stabilization. Nat. Neurosci. Rev. 3: 965-974.
37. Watson, F.L., Heerssen, H.M., Bhattacharyya, A., Klesse, L., Lin, M.Z., and Segal, R. 2001. Neurotrophins use the ERK5 pathway to mediate a retrograde survival response. Nat. Neurosci. 4: 981-988.
38. Wu, G-Y., Deisseroth, K., and Tsien, R.W. 2001. Spaced stimuli stabilize MAPK pathway activation and its effects on dendritic morphology. Nat. Neurosci. 4. 151-158.
39. Yacoubian, T.A. and Lo, D.C. 2000. Truncated and full-length TrkB receptors regulate distinct modes of dendritc growth. Nat. Neurosci. 3: 342-349.
40. Yamamoto, N., Kurotani, T., and Toyama, K. 1989. Neural connections between the lateral geniculate nucleus and visual cortex in vitro. Science 245: 192-194.
41. Ying, S.W., Futter, M., Rosenblum, K., Webber, M.J., Hunt, S.P., Bliss, T.V., and Bramham, C.R. 2002. Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: Requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. J. Neurosci. 22: 1532-1540.
42. Yuste, R. and Bonhoeffer, T. 2001. Morphological changes in dendritic spines associated with long-term synaptic plasticity. Annu. Rev. Neurosci. 24: 1071-1089.
43. Zito, K. and Svoboda, K. 2002. Activity-dependent synaptogenesis in the adult mammalian cortex. Neuron 35: 1015-1017.