Preparation and characterization of paclitaxel-loaded DSPE-PEG-liquid crystalline nanoparticles (LCNPs) for improved bioavailability

International Journal of Pharmaceutics

Volumn 424, Issue 1-2, 2012, Pages 58-66

  Zeng, Ni ^a,b   Hu, Quanyin ^a   Liu, Zhongyang ^a   Gao, Xiaoling ^c   Hu, Rongkuan ^d   Song, Qingxiang ^c   Gu, Guangzhi ^a   Xia, Huimin ^a   Yao, Lei ^c   Pang, Zhiqing ^a   Jiang, Xinguo ^a   Chen, Jun ^a   Fang, Liang ^b  

^a FUDAN UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Crossed polarized light microscopy; DSPE PEG liquid crystalline nanoparticles; Paclitaxel; Sustained release

Indexed keywords

1,2 DISTEAROYL SN GLYCERO 3 PHOSPHATIDYLETHANOLAMINE; DISPERSANT; GENERIC DRUG; LIQUID CRYSTALLINE NANOPARTICLE; MACROGOL; NANOPARTICLE; PACLITAXEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; MALE; MICROSCOPY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; SUSTAINED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DRUG CARRIERS; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PACLITAXEL; PARTICLE SIZE; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84862813598     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.12.058     Document Type: Article

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