Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: Relating plasma circulation lifetimes to protein binding

Biochimica et Biophysica Acta - Biomembranes

Volumn 1768, Issue 6, 2007, Pages 1367-1377

  Dos Santos, Nancy ^a,b   Allen, Christine ^c   Doppen, Anne Marie ^a   Anantha, Malathi ^a   Cox, Kelly A K ^a   Gallagher, Ryan C ^a   Karlsson, Goran ^d   Edwards, Katarina ^d   Kenner, Gail ^b   Samuels, Lacey ^b   Webb, Murray S ^a   Bally, Marcel B ^a,b  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

Cholesterol free; Liposomes; PEG; Plasma elimination; Protein binding

Indexed keywords

1,2 DISTEAROYL SN GLYCERO 3 PHOSPHATIDYLCHOLINE; 1,2 DISTEAROYL SN GLYCERO 3 PHOSPHATIDYLETHANOLAMINE; GLYCEROPHOSPHOLIPID; LIPOSOME; MACROGOL; MACROGOL 2000; POLYMER; UNCLASSIFIED DRUG;

ADSORPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCULATION TIME; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; FREEZE FRACTURE; GEL PERMEATION CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; LIPOSOMAL DELIVERY; MALE; MEMBRANE BINDING; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN BINDING; QUASI EXPERIMENTAL STUDY; TRANSMISSION ELECTRON MICROSCOPY;

ANALYSIS OF VARIANCE; ANIMALS; CHROMATOGRAPHY, GEL; DRUG DELIVERY SYSTEMS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FREEZE FRACTURING; LIPIDS; LIPOSOMES; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; PROTEIN BINDING;

MUS;

EID: 34249044829     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2006.12.013     Document Type: Article

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