Influence of composition and preparation parameters on the properties of aqueous monoolein dispersions

International Journal of Pharmaceutics

Volumn 329, Issue 1-2, 2007, Pages 150-157

  Worle G ^a   Drechsler, M ^a   Koch, M H J ^b   Siekmann, B ^c   Westesen, K ^a   Bunjes, H ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c Camurus AB   (Sweden)

Author keywords

Dispersions of cubic phase; Monoolein; Nanoparticles; Phase behavior; X ray diffraction

Indexed keywords

DRUG CARRIER; GLYCEROL OLEATE; NANOPARTICLE; POLOXAMER;

ARTICLE; DRUG STABILITY; PARTICLE SIZE; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; X RAY DIFFRACTION;

EMULSIONS; GLYCERIDES; NANOPARTICLES; PHASE TRANSITION; POLOXAMER; WATER; X-RAY DIFFRACTION;

EID: 33845600426     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.08.023     Document Type: Article

References (28)

1. Abraham T., Hato M., and Hirai M. Glycolipid based cubic nanoparticles: preparation and structural aspects. Colloid Surf. B 35 (2004) 107-117
2. Barauskas J., Johnsson M., Joabsson F., and Tiberg F. Cubic phase nanoparticles (Cubosome): principles for controlling size, structure, and stability. Langmuir 21 (2005) 2569-2577
3. Barauskas J., Johnsson M., and Tiberg F. Self-assembled superstructures: beyond vesicles and liposomes. Nano Lett. 5 (2005) 1615-1619
4. Boulin C.J., Gabriel A., and Koch M.H.J. Data acquisition systems for linear and area X-ray detectors using delay line readout. Nucl. Instrum. Meth. Phys. Res. A 269 (1988) 312-320
5. Boulin C., Kempf R., Koch M.H.J., and McLaughlin S.M. Data appraisal, evaluation and display for synchrotron radiation experiments: hardware and software. Nucl. Instrum. Meth. A 249 (1986) 399-407
6. Brandl M. High-pressure homogenization techniques for the production of liposome dispersions: potential and limitations. In: Müller R.H., Benita S., and Böhm B.H.L. (Eds). Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs (1998), Medpharm Scientific Publishers, Stuttgart 267-294
7. Briggs J., Chung H., and Caffrey M. The temperature-composition phase diagram and mesophase structure characterization of the monoolein/water system. J. Phys. II (France) 6 (1996) 723-751
8. de Campo L., Yaghmur A., Sagalowicz L., Leser M.E., Watzke H., and Glatter O. Reversible phase transitions in emulsified nanostructured lipid systems. Langmuir 20 (2004) 5254-5261
9. Esposito E., Eblovi N., Rasi S., Drechsler M., di Gregorio G.M., Menegatti E., and Cortesi R. Lipid-based supramolecular systems for topical application: a preformulatory study. AAPS Pharm. Sci. 5 (2003) Article 30
10. Gustafsson J., Ljusberg-Wahren H., Almgren M., and Larsson K. Cubic lipid-water phase dispersed into submicron particles. Langmuir 12 (1996) 4611-4613
11. Gustafsson J., Ljusberg-Wahren H., Almgren M., and Larsson K. Submicron particles of reversed lipid phases in water stabilized by a nonionic amphiphilic polymer. Langmuir 13 (1997) 6964-6971
12. Hyde S.T., Andersson S., Ericsson B., and Larsson K. A cubic structure consisting of a lipid bilayer forming an infinite periodic minimum surface of the gyroid type in the glyceryl monooleate-water system. Z. Kristallogr. 168 (1984) 213-219
13. Koch M.H.J., and Bordas J. X-ray diffraction and scattering on disordered systems using synchrotron radiation. Nucl. Instrum. Meth. 208 (1983) 461-469
14. Landh, T., Larsson, K., 1993. Particles, method of preparing said particles and uses thereof. PCT International Application WO93/06921.
15. Landh T. Phase behavior in the system pine oil monoglycerides-poloxamer 407-water at 20 °C. J. Phys. Chem. 98 (1994) 8453-8467
16. Larsson K. Cubic lipid-water phases: structures and biomembrane aspects. J. Phys. Chem. 93 (1989) 7304-7314
17. Larsson K. Aqueous dispersions of cubic lipid-water phases. Curr. Opin. Colloid Interface Sci. 5 (2000) 64-69
18. Lindström M., Ljusberg-Wahren H., Larsson K., and Borgström B. Aqueous lipid phases of relevance to intestinal fat digestion and absorption. Lipids 16 (1981) 749-754
19. Ljusberg-Wahren H., Nyberg L., and Larsson K. Dispersion of the cubic liquid crystalline phase-structure, preparation and functionality aspects. Chim. Oggi. 14 (1996) 40-43
20. Lyons R.T., and Carter E.G. Lipid emulsions for intravenous nutrition and drug delivery. In: Gunstone F.D., and Padley F.B. (Eds). Lipid Technologies and Applications (1997), Marcel Dekker, New York 535-556
21. 13C NMR investigation on the internal structure of "cubosomes". Langmuir 17 (2001) 3917-3922
22. Shah J.C., Sadhale Y., and Chilukuri D.M. Cubic phase gels as drug delivery systems. Adv. Drug Delivery Rev. 47 (2001) 229-250
23. Siekmann B., Bunjes H., Koch M.H.J., and Westesen K. Preparation and structural investigations of colloidal dispersions prepared from cubic monoglyceride-water phases. Int. J. Pharm. 244 (2002) 33-43
24. Spicer P.T., Hayden K.L., Lynch M.L., Ofori-Boateng A., and Burns J.L. Novel process for producing cubic liquid crystalline nanoparticles (cubosomes). Langmuir 17 (2001) 5748-5756
25. Stang M., Schuchmann H., and Schubert H. Emulsification in high-pressure homogenisers. Eng. Life Sci. 1 (2001) 151-157
26. Um J.Y., Chung H., Kim K.S., Kwon I.C., and Jeong S.Y. In vitro cellular interaction and absorption of dispersed cubic particles. Int. J. Pharm. 253 (2003) 71-80
27. Wörle G., Siekmann B., Koch M.H.J., and Bunjes H. Transformation of vesicular into cubic nanoparticles by autoclaving of aqueous monoolein/poloxamer dispersions. Eur. J. Pharm. Sci. 27 (2006) 44-53
28. Wörle G., Siekmann B., and Bunjes H. Effect of drug loading on the transformation of vesicular into cubic nanoparticles during heat treatment of aqueous monoolein/poloxamer dispersions. Eur. J. Pharm. Biopharm. 63 (2006) 128-133