Poly(caprolactone)-modified Pluronic P105 micelles for reversal of paclitaxcel-resistance in SKOV-3 tumors

Biomaterials

Volumn 33, Issue 18, 2012, Pages 4741-4751

  Wang, Yongzhong ^a,b   Hao, Junguo ^a   Li, Yajuan ^a   Zhang, Zhiwen ^a   Sha, Xianyi ^a   Han, Limei ^a   Fang, Xiaoling ^a  

^a FUDAN UNIVERSITY   (China)

^b ANHUI UNIVERSITY   (China)

Author keywords

Multidrug resistance; Paclitaxel; Ploy(caprolactone); Pluronic; Polymeric micelles

Indexed keywords

CAPROLACTONE; MULTIDRUG RESISTANCE; PACLITAXEL; PLURONICS; POLYMERIC MICELLE;

HYDROGELS; LOADING; MAMMALS; MONOMERS; POLYMERS; TUMORS;

MICELLES;

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; GLYCOPROTEIN P; MONOMER; PACLITAXEL; POLOXAMER; POLOXAMER P 105; POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RESISTANCE; CARCINOMA CELL; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICELLE; MICELLIZATION; MICROENCAPSULATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OVARY; OVARY CARCINOMA; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN TRANSPORT; TUMOR CELL LINE; TUMOR VOLUME; TUMOR XENOGRAFT; UTERUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DRUG CARRIERS; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MICE; MICELLES; OVARIAN NEOPLASMS; PACLITAXEL; POLOXAMER; POLYESTERS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS; MUS MUSCULUS;

EID: 84862787965     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.03.013     Document Type: Article

References (35)

1. Filipits M Mechanisms of cancer: multidrug resistance Drug Discov Today Dis Mech 2004, 1:229-234.
2. Krishna R., Mayer L.D Modulation of P-glycoprotein (PGP) mediated multidrug resistance (MDR) using chemosensitizers: recent advances in the design of selective MDR modulators Curr Med Chem Anticancer Agents 2001, 1:163-174.
3. Zastre J., Jackson J., Burt H Evidence for modulation of P-glycoprotein-mediated efflux by methoxypolyethylene glycol-block-polycaprolactone amphiphilic diblock copolymers Pharm Res 2004, 21:1489-1497.
4. Mamot C., Drummond D.C., Hong K., Kirpotin D.B., Park J.W Liposome-based approaches to overcome anticancer drug resistance Drug Resist Updat 2003, 6:271-279.
5. Kabanov A.V., Batrakova E.V., Alakhov V.Y Pluronic((R)) block copolymers for overcoming drug resistance in cancer Adv Drug Deliv Rev 2002, 54:759-779.
6. Alakhov V., Klinski E., Li S.M., Pietrzynski G., Venne A., Batrakova E., et al Block copolymer-based formulation of doxorubicin From cell screen to clinical trials Colloids Surf B Biointerfaces 1999, 16:113-134.
7. Lee E.S., Na K., Bae Y.H Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor J Control Release 2005, 103:405-418.
8. Wang Y., Yu L., Han L., Sha X., Fang X Difunctional Pluronic copolymer micelles for paclitaxel delivery: synergistic effect of folate-mediated targeting and Pluronic-mediated overcoming multidrug resistance in tumor cell lines Int J Pharm 2007, 337:63-73.
9. Wang Y., Li Y., Zhang L., Fang X Pharmacokinetics and biodistribution of paclitaxel-loaded pluronic P105 polymeric micelles Arch Pharm Res 2008, 31:530-538.
10. Kim S.Y., Lee Y.M Taxol-loaded block copolymer nanospheres composed of methoxy poly(ethylene glycol) and poly(epsilon-caprolactone) as novel anticancer drug carriers Biomaterials 2001, 22:1697-1704.
11. Zastre J., Jackson J., Bajwa M., Liggins R., Iqbal F., Burt H Enhanced cellular accumulation of a P-glycoprotein substrate, rhodamine-123, by Caco-2 cells using low molecular weight methoxypolyethylene glycol-block-polycaprolactone diblock copolymers Eur J Pharm Biopharm 2002, 54:299-309.
12. Ha J.C., Kim S.Y., Lee Y.M Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (pluronic)/poly(epsilon-caprolactone) (PCL) amphiphilic block copolymeric nanospheres - I Preparation and characterization J Control Release 1999, 62:381-392.
13. Kim S.Y., Ha J.C., Lee Y.M Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide)/poly(epsilon-caprolactone) (PCL) amphiphilic block copolymeric nanospheres - II Thermo-responsive drug release behaviors J Control Release 2000, 65:345-358.
14. Ge H., Hu Y., Jiang X., Cheng D., Yuan Y., Bi H., et al Preparation, characterization, and drug release behaviors of drug nimodipine-loaded poly(epsilon- caprolactone)-poly(ethylene oxide)-poly(epsilon- caprolactone) amphiphilic triblock copolymer micelles J Pharm Sci 2002, 91:1463-1473.
15. Shin I.G., Kim S.Y., Lee Y.M., Cho C.S., Sung Y.K Methoxy poly(ethylene glycol)/[epsilon]-caprolactone amphiphilic block copolymeric micelle containing indomethacin.: I Preparation and characterization J Control Release 1998, 51:1-11.
16. Han L., Pan H., Fang X Establishment and biological characterization of paclitaxel-resistant cell line of human ovarian carcinoma Fudan Univ J Med Sci 2008, 35:171-175.
17. Miller D.W., Batrakova E.V., Waltner T.O., Alakhov V., Kabanov A.V Interactions of pluronic block copolymers with brain microvessel endothelial cells: evidence of two potential pathways for drug absorption Bioconjug Chem 1997, 8:649-657.
18. Garewal H.S., Ahmann F.R., Schifman R.B., Celniker A ATP assay: ability to distinguish cytostatic from cytocidal anticancer drug effects J Natl Cancer Inst 1986, 77:1039-1045.
19. Salvioli S., Barbi C., Dobrucki J., Moretti L., Pinti M., Pedrazzi J., et al Opposite role of changes in mitochondrial membrane potential in different apoptotic processes FEBS Lett 2000, 469:186-190.
20. Marchetti P., Castedo M., Susin S.A., Zamzami N., Hirsch T., Macho A., et al Mitochondrial permeability transition is a central coordinating event of apoptosis J Exp Med 1996, 184:1155-1160.
21. Simon L., Szilagyi G., Bori Z., Telek G., Magyar K., Nagy Z Low dose (-)deprenyl is cytoprotective: it maintains mitochondrial membrane potential and eliminates oxygen radicals Life Sci 2005, 78:225-231.
22. de Laat S.W., van der Saag P.T., Shinitzky M Microviscosity modulation during the cell cycle of neuroblastoma cells Proc Natl Acad Sci U S A 1977, 74:4458-4461.
23. Batrakova E.V., Li S., Vinogradov S.V., Alakhov V.Y., Miller D.W., Kabanov A.V Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization J Pharmacol Exp Ther 2001, 299:483-493.
24. Batrakova E.V., Li S., Alakhov V.Y., Elmquist W.F., Miller D.W., Kabanov A.V Sensitization of cells overexpressing multidrug-resistant proteins by Pluronic P85 Pharm Res 2003, 20:1581-1590.
25. Kim S.C., Kim D.W., Shim Y.H., Bang J.S., Oh H.S., Kim S.W., et al In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy J Control Release 2001, 72:191-202.
26. Yoo H.S., Park T.G Folate receptor targeted biodegradable polymeric doxorubicin micelles J Control Release 2004, 96:273-283.
27. Wang C.H., Tang C.W., Liu C.L., Tang L.P Inhibitory effect of octreotide on gastric cancer growth via MAPK pathway World J Gastroenterol 2003, 9:1904-1908.
28. Rapoport N., Pitt W.G., Sun H., Nelson J.L Drug delivery in polymeric micelles: from in vitro to in vivo J Control Release 2003, 91:85-95.
29. Lee J.S., Paull K., Alvarez M., Hose C., Monks A., Grever M., et al Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen Mol Pharmacol 1994, 46:627-638.
30. Wang Y.Z., Fang X.L., Li Y.J., Zhang Z.W., Han L.M., Sha X.Y Preparation, characterization of paclitaxel-loaded Pluronic P105 polymeric micelles and in vitro reversal of multidrug resistant tumor Acta Pharmaceutica Sinica 2008, 43:640-646.
31. Gao Z.G., Fain H.D., Rapoport N Controlled and targeted tumor chemotherapy by micellar-encapsulated drug and ultrasound J Control Release 2005, 102:203-222.
32. Kabanov A.V., Batrakova E.V., Alakhov V.Y Pluronic (R) block copolymers as novel polymer therapeutics for drug and gene delivery J Control Release 2002, 82:189-212.
33. Batrakova E., Lee S., Li S., Venne A., Alakhov V., Kabanov A Fundamental relationships between the composition of Pluronic block copolymers and their hypersensitization effect in MDR cancer cells Pharm Res 1999, 16:1373-1379.
34. Wang Y., Li Y., Wang Q., Fang X Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with pluronic P105/poly(caprolactone) copolymers Pharmazie 2008, 63:446-452.
35. Kwon G.S., Okano T Polymeric micelles as new drug carriers Adv Drug Deliv Rev 1996, 21:107-116.