Nucleotides released from Aβ 1-42-treated microglial cells increase cell migration and Aβ 1-42 uptake through P2Y 2 receptor activation

Journal of Neurochemistry

Volumn 121, Issue 2, 2012, Pages 228-238

  Kim, Hye Jung ^a,b,c   Ajit, Deepa ^a,c   Peterson, Troy S ^c   Wang, Yanfang ^a,c   Camden, Jean M ^a,c   Wood, W Gibson ^d   Sun, Grace Y ^a,c   Erb, Laurie ^a,c   Petris, Michael ^a,c   Weisman, Gary A ^a,c  

^a University of Missouri   (United States)

^b Gyeongsang National University   (South Korea)

^c UNIVERSITY OF MISSOURI   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

amyloid phagocytosis; Alzheimer's disease; Microglia; Migration; Nucleotide; P2y 2 receptor

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; AMYLOID BETA PROTEIN[1-42]; APYRASE; CD51 ANTIGEN; NUCLEOTIDE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PURINERGIC P2Y2 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; RAC PROTEIN; STEROID RECEPTOR COACTIVATOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL ISOLATION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; MALE; MICROGLIA; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; AMYLOID BETA-PEPTIDES; ANIMALS; BLOTTING, WESTERN; CELL MOVEMENT; CELL SEPARATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INTEGRIN ALPHA5; L-LACTATE DEHYDROGENASE; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; MICROSCOPY, ELECTRON, TRANSMISSION; NEUROFIBRILS; NUCLEOTIDES; PEPTIDE FRAGMENTS; PHAGOCYTOSIS; PURINERGIC P2Y RECEPTOR AGONISTS; RAC GTP-BINDING PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PURINERGIC P2Y2; RNA, MESSENGER; SRC-FAMILY KINASES; URIDINE TRIPHOSPHATE;

MUS;

EID: 84862777045     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07700.x     Document Type: Article

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