Arachidonate-enriched triglyceride oil does not promote tumor development in a rat medium-term multi-organ carcinogenesis model

Food and Chemical Toxicology

Volumn 50, Issue 8, 2012, Pages 2780-2791

  Imai, Norio ^a   Kawabe, Mayumi ^a   Tamano, Seiko ^a   Doi, Yuko ^a   Nakashima, Hironao ^a   Suguro, Mayuko ^a   Numano, Takamasa ^a   Hara, Tomomi ^a   Hagiwara, Akihiro ^a   Furukawa, Fumio ^a   Kaneda, Yoshihisa ^b   Tateishi, Norifumi ^c   Fujii, Wataru ^b   Kawashima, Hiroshi ^c   Shibata, Hiroshi ^c   Sakakibara, Yutaka ^b  

^a Daiyukai Research Institute for Medical Science   (Japan)

^b SUNTORY LTD   (Japan)

^c Suntory Wellness Limited Research Center   (Japan)

Author keywords

Arachidonate enriched triglyceride oil; F344 rats; Multi organ carcinogenesis bioassay; No tumor promotion

Indexed keywords

1,2 DIMETHYLHYDRAZINE; ARACHIDONIC ACID; BIS(2 HYDROXYPROPYL)NITROSAMINE; CARCINOGEN; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE; METHYLNITROSOUREA; N,N BUTYL N BUTAN 4 OL NITROSAMINE; NITROSAMINE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; BLADDER; CANCER INCIDENCE; CARCINOGENESIS; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; HYPERPLASIA; KIDNEY; LARGE INTESTINE; LIVER; LUNG; MALE; MAMMARY GLAND; NEOPLASM; NONHUMAN; PLACENTA; RAT; THYROID GLAND; UTERUS;

ANIMALS; ARACHIDONIC ACID; BODY WEIGHT; CELL TRANSFORMATION, NEOPLASTIC; DRINKING BEHAVIOR; FEEDING BEHAVIOR; FEMALE; MALE; NEOPLASMS, EXPERIMENTAL; ORGAN SIZE; RATS; RATS, INBRED F344; TRIGLYCERIDES;

ANIMALIA; ARA; RATTUS;

EID: 84862702712     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.004     Document Type: Article

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