Early detection of carcinogenic substances and modifiers in rats

Mutation Research - Reviews in Mutation Research

Volumn 462, Issue 2-3, 2000, Pages 209-217

  Ito, Nobuyuki ^a   Imaida, Katsumi ^b   Asamoto, Makoto ^b   Shirai, Tomoyuki ^b  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

Carcinogenesis; Liver; Medium term bioassay; Rat; Screening of carcinogens

Indexed keywords

1,2 DIMETHYLHYDRAZINE; 2',3 DIMETHYL 4 BIPHENYLAMINE; AFLATOXIN B1; ALPHA TOCOPHEROL; BIS(2 HYDROXYPROPYL)NITROSAMINE; BUTYLATED HYDROXYANISOLE; BUTYLCRESOL; CAFFEIC ACID; CAPTAN; CARCINOGEN; CATECHOL; CLOFIBRATE; DIETHYLNITROSAMINE; DIETHYLSTILBESTROL; ETHIONINE; IMIDAZOLE DERIVATIVE; INDOMETACIN; LIMONENE; MEQUINOL; METHYLNITRONITROSOGUANIDINE; N (2 FLUORENYL)ACETAMIDE; PARACETAMOL; PRASTERONE; QUERCETIN; SODIUM NITRITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CARCINOGEN TESTING; CARCINOGENESIS; CARCINOGENICITY; CONTROLLED STUDY; LIVER CANCER; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; REVIEW; SCREENING TEST;

SALMONELLA;

EID: 0034037455     PISSN: 13835742     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5742(00)00038-7     Document Type: Article

References (37)

1. McCann J., Spingarn N.E., Kobori J., Ames B.N. Detection of carcinogens as mutagens: bacterial tester strains with r factor plasmids. Proc. Natl. Acad. Sci. USA. 72:1975;979-983.
2. Chan V.T., McGee J.O. Cellular oncogenes in neoplasia. J. Clin. Pathol. 40:1987;1055-1063.
3. Ishidate M. Jr., Harnois M.C., Sofuni T. A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures. Mutat. Res. 195:1988;151-213.
4. Zeiger E. Carcinogenicity of mutagens: predictive capability of the Salmonella mutagenesis assay for rodent carcinogenicity. Cancer Res. 47:1987;1287-1296.
5. N. Ito, K. Imaida, R. Hasegawa, H. Tsuda, Rapid bioassay methods for carcinogens and modifiers of hepatocarcinogenesis, in: R.Õ. McClellan (Ed.), Critical Reviews in Toxicology, CRC Press, FL, 1989, pp. 385-415.
6. N. Ito, T. Shirai, R. Hasegawa, Medium-term bioassays for carcinogens, in: H. Vainio, P. Magee, D. McGregor, A.J. McMichael (Eds.), Mechanisms of Carcinogenesis in Risk Assessment, IARC Scientific Publications, No. 116, Lyon, 1992, pp. 353-388.
7. Ito N., Hasegawa R., Imaida K., Hirose M., Shirai T. Medium-term liver and multi-organ carcinogenesis bioassays for carcinogens and chemopreventive agents. Exp. Toxicol. Pathol. 48:1996;113-119.
8. Ito N., Hasegawa R., Imaida K., Hirose M., Shirai T., Tamano S., Hagiwara A. Medium-term rat liver bioassay for rapid detection of hepatocarcinogenic substances. J. Toxicol. Pathol. 10:1997;1-11.
9. Tsuda H., Hasegawa R., Imaida K., Masui T., Moore M.A., Ito N. Modifying potential of thirty-one chemicals on the short-term development of γ-glutamyl transpeptidase-positive foci in diethylnitrosamine-initiated rat liver. Gann. 75:1984;876-883.
10. ICH Steering Committee, ICH4, Fourth International Conference on Harmonization: Carcinogenicity: Testing for Carcinogenicity of Pharmaceuticals, 1997.
11. Kew M.C. The development of hepatocellular cancer in humans. Cancer Surv. 5:1986;719-739.
12. Solt D., Farber E. New principle for the analysis of chemical carcinogenesis. Nature. 263:1976;701-703.
13. Tatematsu M., Shirai T., Tsuda H., Miyata Y., Shinohara Y., Ito N. Rapid production of hyperplastic liver nodules in rats treated with carcinogenic chemicals: a new approach for an in vivo short-term screening test for hepatocarcinogens. Gann. 68:1977;499-507.
14. Imaida K., Shirai T., Tatematsu M., Takano T., Ito N. Dose responses of five hepatocarcinogens for the initiation of rat hepatocarcinogenesis. Cancer Lett. 14:1981;279-283.
15. 1. Jpn. J. Cancer Res. 76:1985;16-19.
16. Hasegawa R., Tsuda H., Shirai T., Kurata Y., Masuda A., Ito N. Effect of timing of partial hepatectomy on the induction of preneoplastic liver foci in rats given hepatocarcinogens. Cancer Lett. 32:1986;15-23.
17. Tatematsu M., Murasaki G., Nakanishi K., Miyata Y., Shinohara Y., Ito N. Sequential quantitative studies on hyperplastic nodules in the liver of rats treated with carcinogenic chemicals. Gann. 70:1979;125-130.
18. Hasegawa R., Tsuda H., Nakanishi K., Tatematsu M., Ito N. Route-dependent, organ-specific effects of carcinogens on induction of hyperplastic liver nodules in rats. Toxicol. Lett. 14:1982;229-235.
19. Tatematsu M., Takano T., Hasegawa R., Imaida K., Nakanowatari J., Ito N. A sequential quantitative study of the reversibility or irreversibility of liver hyperplastic nodules in rats exposed to hepatocarcinogens. Gann. 71:1980;843-855.
20. Bannasch P. Preneoplastic lesions as end points in carcinogenicity testing: I. Hepatic preneoplasia. Carcinogenesis. 7:1986;689-695.
21. Sato K., Kitahara A., Satoh K., Ishikawa T., Tatematsu M., Ito N. The placental form of glutathione S-transferase as a new marker protein for preneoplasia in rat chemical hepatocarcinogenesis. Gann. 75:1984;199-202.
22. Tatematsu M., Mera Y., Ito N., Satoh K., Sato K. Relative merits of immunohistochemical demonstrations of placental, A, B and C forms of glutathione S-transferase and histochemical demonstration of gamma-glutamyl transferase as markers of altered foci during liver carcinogenesis in rats. Carcinogenesis. 6:1985;1621-1626.
23. Asamoto M., Tsuda H., Kagawa M., de Camargo J.L., Ito N., Nagase S. Strain differences in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of rat hepatocarcinogenesis in a medium-term assay system: quantitation of glutathione S-transferase P-positive foci development. Jpn. J. Cancer Res. 80:1989;939-944.
24. Ogiso T., Tatematsu M., Tamano S., Tsuda H., Ito N. Comparative effects of carcinogens on the induction of placental glutathione S-transferase-positive liver nodules in a short-term assay and of hepatocellular carcinomas in a long-term assay. Toxicol. Pathol. 13:1985;257-265.
25. Ito N., Imaida K., Tsuda H., Shibata M., Aoki T., de Camargo J.L., Fukushima S. Wide-spectrum initiation models: possible applications to medium-term multiple organ bioassays for carcinogenesis modifiers. Jpn. J. Cancer Res. 79:1988;413-417.
26. Tsuda H., Fukushima S., Imaida K., Kurata Y., Ito N. Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea. Cancer Res. 43:1983;3292-3296.
27. Diwan B.A., Palmer A.E., Ohshima M., Rice J.M. N-Nitroso-N-methylurea initiation in multiple tissues for organ-specific tumor promotion in rats by phenobarbital. J. National Cancer Inst. 75:1985;1099-1105.
28. Hirose M., Ozaki K., Takaba K., Fukushima S., Shirai T., Ito N. Modifying effects of the naturally occurring antioxidants gamma-oryzanol, phytic acid, tannic acid and n-tritriacontane-16,18-dione in a rat wide-spectrum organ carcinogenesis model. Carcinogenesis. 12:1991;1917-1921.
29. Fukushima S., Hagiwara A., Hirose M., Yamaguchi S., Tiwawech D., Ito N. Modifying effects of various chemicals on preneoplastic and neoplastic lesion development in a wide-spectrum organ carcinogenesis model using F344 rats. Jpn. J. Cancer Res. 82:1991;642-649.
30. Hasegawa R., Cabral R., Hoshiya T., Hakoi K., Ogiso T., Boonyaphiphat P., Shirai T., Ito N. Carcinogenic potential of some pesticides in a medium-term multi-organ bioassay in rats. Int. J. Cancer. 54:1993;489-493.
31. Hirose M., Yada H., Hakoi K., Takahashi S., Ito N. Modification of carcinogenesis by alpha-tocopherol, t-butylhydroquinone, propyl gallate and butylated hydroxytoluene in a rat multi-organ carcinogenesis model. Carcinogenesis. 14:1993;2359-2364.
32. Hagiwara A., Tanaka H., Imaida K., Tamano S., Fukushima S., Ito N. Correlation between medium-term multi-organ carcinogenesis bioassay data and long-term observation results in rats. Jpn. J. Cancer Res. 84:1993;237-245.
33. Hasegawa R., Tanaka H., Tamano S., Shirai T., Nagao M., Sugimura T., Ito N. Synergistic enhancement of small and large intestinal carcinogenesis by combined treatment of rats with five heterocyclic amines in a medium-term multi-organ bioassay. Carcinogenesis. 15:1994;2567-2573.
34. Kimura J., Takahashi S., Ogiso T., Yoshida Y., Akagi K., Hasegawa R., Kurata M., Hirose M., Shirai T. Lack of chemoprevention effects of the monoterpene D-limonene in a rat multi-organ carcinogenesis model. Jpn. J. Cancer Res. 87:1996;589-594.
35. + staining foci by the rat hepatocarcinogen methapyrilene in the medium-term bioassay. Fundam. Appl. Toxicol. 29:1996;194-197.
36. Kim D.J., Lee K.K., Han B.S., Ahn B., Bae J.H., Jang J.J. Biphasic modifying effect of indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats. Jpn. J. Cancer Res. 85:1994;578-583.
37. Jang J.J., Cho K.J., Lee Y.S., Bae J.H. Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model. Carcinogenesis. 12:1991;691-695.