A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 11, 2010, Pages 2563-2570

  Chang, C H ^a   Chung, C H ^b   Hsu, C C ^a   Huang, T Y ^a   Huang, T F ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Aggretin; CLEC 2; Inflammation; Snake venom C type lectin proteins

Indexed keywords

AGGRETIN; C TYPE LECTIN LIKE RECEPTOR 2; C TYPE LECTIN LIKE RECEPTOR 2 MONOCLONAL ANTIBODY; CELL SURFACE RECEPTOR; CONVULXIN; GRAMICETIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LECTIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; NATURAL KILLER CELL LECTIN LIKE RECEPTOR; SNACLECS; SNAKE VENOM; STRESS ACTIVATED PROTEIN KINASE; TROWAGLERIX; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL LYSATE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FLUORESCENCE ACTIVATED CELL SORTING; IMMOBILIZED CELL; LEUKEMIA CELL; LIGATION; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; WESTERN BLOTTING;

ANIMALS; CYTOKINES; INFLAMMATION; INTERLEUKIN-6; LECTINS, C-TYPE; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED ICR; MONOCYTES; NF-KAPPA B; PHAGOCYTES; SNAKE VENOMS; TUMOR NECROSIS FACTOR-ALPHA; VIPER VENOMS;

EID: 78149273064     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2010.04045.x     Document Type: Article

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