Modular synthesis of folate conjugated ternary copolymers: Polyethylenimine-graft-polycaprolactone-block-poly(ethylene glycol)-folate for targeted gene delivery

Bioconjugate Chemistry

Volumn 23, Issue 6, 2012, Pages 1211-1220

  Liu, Li ^a,b   Zheng, Mengyao ^a   Renette, Thomas ^a   Kissel, Thomas ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; CYTOLOGY; ELECTROPHORESIS; ETHYLENE GLYCOL; GENE TRANSFER; GENES; GRAFTING (CHEMICAL); MOLECULAR BIOLOGY; POLYCAPROLACTONE; POLYETHYLENE OXIDES; POLYOLS; TUMORS; ULTRAVIOLET SPECTROSCOPY;

CELLULAR UPTAKE; FOLATE RECEPTOR; FOLATES; HUMAN CANCER; MODULAR SYNTHESIS; N:P RATIO; POLY(ETHYLENIMINE); POLYPLEXES; RECEPTOR-MEDIATED ENDOCYTOSIS; TARGETED GENE DELIVERY;

POLYETHYLENE GLYCOLS;

COPOLYMER; FOLATE RECEPTOR; FOLIC ACID DERIVATIVE; POLYETHYLENIMINE GRAFT POLYCAPROLACTONE BLOCK POLY(ETHYLENE GLYCOL)FOLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; ENDOCYTOSIS; FLOW CYTOMETRY; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; MICHAEL ADDITION; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL;

CELL LINE, TUMOR; CLICK CHEMISTRY; DNA; ENDOCYTOSIS; FOLIC ACID; HUMANS; NEOPLASMS; POLYESTERS; POLYETHYLENEIMINE; TRANSFECTION;

EID: 84862686619     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc300025d     Document Type: Article

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