The therapeutic efficiency of FP-PEA/TAM67 gene complexes via folate receptor-mediated endocytosis in a xenograft mice model

Biomaterials

Volumn 31, Issue 8, 2010, Pages 2435-2445

  Arote, Rohidas B ^a,b   Hwang, Soon Kyung ^b   Lim, Hwang Tae ^b   Kim, Tae Hee ^a,c   Jere, Dhananjay ^a   Jiang, Hu Lin ^a,b   Kim, You Kyoung ^a   Cho, Myung Haing ^b,d   Cho, Chong Su ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c University of Washington   (United States)

^d Seoul National University   (South Korea)

Author keywords

Angiogenesis; Biodegradable; Folate receptor mediated endocytosis; Poly(ester amine)

Indexed keywords

ANGIOGENESIS; ANTI-TUMOR ACTIVITIES; APOPTOSIS; BIODEGRADABLE; FOLATE RECEPTOR; FOLATE RECEPTOR-MEDIATED ENDOCYTOSIS; FOLIC ACIDS; GENE CARRIER; GENE COMPLEXES; GENE DELIVERY; HIGH AFFINITY; IN-VITRO; IN-VIVO; LOW MOLECULAR WEIGHT; MICE MODELS; NUDE MICE; POLYETHYLENIMINES; RECEPTOR-MEDIATED ENDOCYTOSIS; SPECIFIC ACTIVITY; THERAPEUTIC BENEFITS; THERAPEUTIC EFFECTS; THERAPEUTIC EFFICIENCY; THERAPEUTIC STRATEGY; TUMOR TARGETING; WEIGHT LOSS;

ACOUSTOELECTRIC EFFECTS; CELL CULTURE; CELL DEATH; ESTERIFICATION; ESTERS; GENE THERAPY; GENE TRANSFER; NUCLEIC ACIDS; ORGANIC ACIDS; POLYCAPROLACTONE; TOXICITY; TUMORS;

PIEZOELECTRIC DEVICES;

FOLATE RECEPTOR; FOLIC ACID; POLYAMINE; POLYCAPROLACTONE; POLYETHYLENEIMINE; PROTEIN TAM67; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CULTURE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; ENDOCYTOSIS; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MALE; MOUSE; MOUTH CANCER; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TUMOR CELL;

ANIMALS; CARRIER PROTEINS; DRUG CARRIERS; ENDOCYTOSIS; FOLIC ACID; GENE TRANSFER TECHNIQUES; HUMANS; MALE; MATERIALS TESTING; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR STRUCTURE; NEOPLASM TRANSPLANTATION; NEOPLASMS; PEPTIDE FRAGMENTS; POLYAMINES; POLYESTERS; POLYETHYLENEIMINE; PROTO-ONCOGENE PROTEINS C-JUN; RECEPTORS, CELL SURFACE; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS; MUS MUSCULUS;

EID: 74449087801     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.11.106     Document Type: Article

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