Deoxyribonucleic Acid Response Element-Dependent Regulation of Transcription by Orphan Nuclear Receptor Estrogen Receptor-Related Receptor γ

Molecular Endocrinology

Volumn 18, Issue 2, 2004, Pages 312-325

  Sanyal, Sabyasachi ^a   Matthews, Jason ^a   Bouton, Didier ^a   Kim, Han Jong ^b   Choi, Hueng Sik ^b   Treuter, Eckardt ^a   Gustafsson, Jan Åke ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR RELATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR; RECEPTOR SUBTYPE; REGULATOR PROTEIN; REPRESSOR PROTEIN; STEROIDOGENIC FACTOR 1; THYROID HORMONE; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ESTROGEN RESPONSIVE ELEMENT; GEL MOBILITY SHIFT ASSAY; HORMONE RECEPTOR INTERACTION; HUMAN; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RECEPTOR AFFINITY; RECEPTOR SENSITIVITY; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELLS, CULTURED; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; NUCLEAR PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, ESTROGEN; RESPONSE ELEMENTS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRYPSIN;

ANIMALIA;

EID: 0842291438     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2003-0165     Document Type: Article

References (53)

1. Giguere V, Yang N, Segui P, Evans RM 1988 Identification of a new class of steroid hormone receptors. Nature 331:91-94
2. Tremblay GB, Bergeron D, Giguere V 2001 4-Hydroxytamoxifen is an isoform-specific inhibitor of orphan estrogen-receptor-related (ERR) nuclear receptors β and γ. Endocrinology 142:4572-4575
3. Tremblay GB, Kunath T, Bergeron D, Lapointe L, Champigny C, Bader JA, Rossant J, Giguere V 2001 Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERRβ. Genes Dev 15:833-838
4. Coward P, Lee D, Hull MV, Lehmann JM 2001 4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor γ. Proc Natl Acad Sci USA 98: 8880-8884
5. Sladek R, Bader JA, Giguere V 1997 The orphan nuclear receptor estrogen-related receptor α is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Mol Cell Biol 17:5400-5409
6. Hong H, Yang L, Stallcup MR 1999 Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3. J Biol Chem 274: 22618-22626
7. Heard DJ, Norby PL, Holloway J, Vissing H 2000 Human ERRγ, a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: tissue-specific isoforms are expressed during development and in the adult. Mol Endocrinol 14:382-392
8. Sanyal S, Kim JY, Kim HJ, Takeda J, Lee YK, Moore DD, Choi HS 2002 Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. J Biol Chem 277:1739-1748
9. Luo J, Sladek R, Bader JA, Matthyssen A, Rossant J, Giguere V 1997 Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-β. Nature 388:778-782
10. Pettersson K, Svensson K, Mattsson R, Carlsson B, Ohlsson R, Berkenstam A 1996 Expression of a novel member of estrogen response element-binding nuclear receptors is restricted to the early stages of chorion formation during mouse embryogenesis. Mech Dev 54: 211-223
11. Vanacker JM, Bonnelye E, Chopin-Delannoy S, Delmarre C, Cavailles V, Laudet V 1999 Transcriptional activities of the orphan nuclear receptor ERR α (estrogen receptor-related receptor-α). Mol Endocrinol 13:764-773
12. Xie W, Hong H, Yang NN, Lin RJ, Simon CM, Stallcup MR, Evans RM 1999 Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2. Mol Endocrinol 13:2151-2162
13. Zhang Z, Teng CT 2000 Estrogen receptor-related receptor α 1 interacts with coactivator and constitutively activates the estrogen response elements of the human lactoferrin gene. J Biol Chem 275:20837-20846
14. Greschik H, Wurtz JM, Sanglier S, Bourguet W, van Dorsselaer A, Moras D, Renaud JP 2002 Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3. Mol Cell 9:303-313
15. Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM 1998 A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92:829-839
16. Knutti D, Kaul A, Kralli A 2000 A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen. Mol Cell Biol 20:2411-2422
17. Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP 2000 Peroxisome proliferator-activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 106:847-856
18. Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman, BM 2001 Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413:131-138
19. Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M 2001 CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413: 179-183
20. Vega RB, Huss JM, Kelly DP 2000 The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor α in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol Cell Biol 20:1868-1876
21. Lee CH, Chinpaisal C, Wei LN 1998 Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2. Mol Cell Biol 18:6745-6755
22. Lee CH, Wei LN 1999 Characterization of receptor-interacting protein 140 in retinoid receptor activities. J Biol Chem 274:31320-31326
23. Miyata KS, McCaw SE, Meertens LM, Patel HV, Rachubinski RA, Capone JP 1998 Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor α and liver-X-receptor α. Mol Cell Endocrinol 146:69-76
24. Subramaniam N, Treuter E, Okret S 1999 Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoids. J Biol Chem 274:18121-18127
25. Treuter E, Albrektsen T, Johansson L, Leers J, Gustafsson JA 1998 A regulatory role for RIP140 in nuclear receptor activation. Mol Endocrinol 12:864-881
26. Vo N, Fjeld C, Goodman RH 2001 Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP. Mol Cell Biol 21:6181-6188
27. Wei LN, Hu X, Chandra D, Seto E, Farooqui M 2000 Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing. J Biol Chem 275: 40782-40787
28. Wei LN, Farooqui M, Hu X 2001 Ugand-dependent formation of retinoid receptors, receptor-interacting protein 140 (RIP140), and histone deacetylase complex is mediated by a novel receptor-interacting motif of RIP140. J Biol Chem 276:16107-16112
29. Knutti D, Kressler D, Kralli A 2001 Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor. Proc Natl Acad Sci USA 98: 9713-9718
30. Bonnelye E, Kung V, Laplace C, Galson DL, Aubin JE 2002 Estrogen receptor-related receptor α impinges on the estrogen axis in bone: potential function in osteoporosis. Endocrinology 143:3658-3670
31. Giguere V 2002 To ERR in the estrogen pathway. Trends Endocrinol Metab 13:220-225
32. Bonnelye E, Aubin JE 2002 Differential expression of estrogen receptor-related receptor α and estrogen receptors α and β in osteoblasts in vivo and in vitro. J Bone Miner Res 17:1392-1400
33. Kraus RJ, Ariazi EA, Farrell ML, Mertz JE 2002 Estrogen-related receptor α 1 actively antagonizes estrogen receptor-regulated transcription in MCF-7 mammary cells. J Biol Chem 277:24826-24834
34. Bonnelye E, Merdad L, Kung V, Aubin JE 2001 The orphan nuclear estrogen receptor-related receptor alpha (ERRα) is expressed throughout osteoblast differentiation and regulates bone formation in vitro. J Cell Biol 153:971-984
35. Vanacker JM, Delmarre C, Guo X, Laudet V 1998 Activation of the osteopontin promoter by the orphan nuclear receptor estrogen receptor related α. Cell Growth Differ 9:1007-1014
36. Trapp T, Holsboer F 1996 Nuclear orphan receptor as a repressor of glucocorticoid receptor transcriptional activity. J Biol Chem 271:9879-9882
37. Huss JM, Kopp RP, Kelly DP 2002 Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1α) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-α and -γ. Identification of novel leucine-rich interaction motif within PGC-1α. J Biol Chem 277:40265-40274
38. Ichida M, Nemoto S, Finkel T 2002 Identification of a specific molecular repressor of the peroxisome proliferator-activated receptor γ coactivator-1 α (PGC-1α). J Biol Chem 277:50991-50995
39. Hentschke M, Susens U, Borgmeyer U 2002 PGC-1 and PERC, coactivators of the estrogen receptor-related receptor γ. Biochem Biophys Res Commun 299:872-879
40. Hentschke M, Susens U, Borgmeyer U 2002 Domains of ERRγ that mediate homodimerization and interaction with factors stimulating DNA binding. Eur J Biochem 269:4086-4097
41. Wood JR, Ukhite VS, Loven MA, Nardulli AM 2001 Allosteric modulation of estrogen receptor conformation by different estrogen response elements. Mol Endocrinol 15:1114-1126
42. Wood JR, Greene GL, Nardulli AM 1998 Estrogen response elements function as allosteric modulators of estrogen receptor conformation. Mol Cell Biol 18: 1927-1934
43. Takeshita A, Yen PM, Ikeda M, Cardona GR, Liu Y, Koibuchi N, Norwitz E, Chin WW 1998 Thyroid hormone response elements differentially modulate the interactions of thyroid hormone receptors with two receptor binding domains in the steroid receptor coactivator-1. J Biol Chem 273:21554-21562
44. Ikeda M, Wilcox EC, Chin WW 1996 Different DNA elements can modulate the conformation of thyroid hormone receptor heterodimer and its transcriptional activity. J Biol Chem 271:23096-23104
45. Scully KM, Jacobson EM, Jepsen K, Lunyak V, Viadiu H, Carriere C, Rose DW, Hooshmand F, Aggarwal AK, Rosenfeld MG 2000 Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification. Science 290:1127-1131
46. Tcherepanova I, Puigserver P, Norris JD, Spiegelman BM, McDonnell DP 2000 Modulation of estrogen receptor-α transcriptional activity by the coactivator PGC-1. J Biol Chem 275:16302-16308
47. Wu Y, Delerive P, Chin WW, Burris TP 2002 Requirement of helix 1 and the AF-2 domain of the thyroid hormone receptor for coactivation by PGC-1. J Biol Chem 277: 8898-8905
48. Schreiber SN, Knutti D, Brogli K, Uhlmann T, Kralli A 2003 The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor α (ERRα). J Biol Chem 278: 9013-9018
49. Soutoglou E, Papafotiou G, Katrakili N, Talianidis I 2000 Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins. J Biol Chem 275:12515-12520
50. Kassam A, Capone JP, Rachubinski RA 2001 The short heterodimer partner receptor differentially modulates peroxisome proliferator-activated receptor α-mediated transcription from the peroxisome proliferator-response elements of the genes encoding the peroxisomal β-oxidation enzymes acyl-CoA oxidase and hydratase-dehydrogenase. Mol Cell Endocrinol 176:49-56
51. Brendel C, Schoonjans K, Botrugno OA, Treuter E, Auwerx J 2002 The small heterodimer partner interacts with the liver X receptor α and represses its transcriptional activity. Mol Endocrinol 16:2065-2076
52. Loven MA, Likhite VS, Choi I, Nardulli AM 2001 Estrogen response elements alter coactivator recruitment through allosteric modulation of estrogen receptor β conformation. J Biol Chem 276:45282-45288
53. Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M 2000 Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103:843-852