Molecular effects of doxycycline treatment on pterygium as revealed by massive transcriptome sequencing

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Larráyoz, Ignacio M ^a   de Luis, Alberto ^a   Rúa, Oscar ^b   Velilla, Sara ^b   Cabello, Juan ^a   Martínez, Alfredo ^a  

^a CENTER FOR BIOMEDICAL RESEARCH OF LA RIOJA CIBIR   (Spain)

^b HOSPITAL SAN PEDRO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN ZETA; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DOXYCYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIBRONECTIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; GROWTH FACTOR; INTEGRIN; INTERLEUKIN 6; MESSENGER RNA; MITOCHONDRIAL DNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN IRE1; PROTEIN KINASE R; PROTEIN P21; PROTEIN P53; RIBOSOME RNA; SCLEROPROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; TRANSCRIPTOME; UNCLASSIFIED DRUG; VASCULOTROPIN A; VIMENTIN;

ADULT; ARTICLE; CELL CYCLE ARREST; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MITOCHONDRIAL GENE; PTERYGIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PURIFICATION; SEQUENCE ANALYSIS; TISSUE CULTURE; TREATMENT OUTCOME;

ADULT; CLUSTER ANALYSIS; DOXYCYCLINE; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, MITOCHONDRIAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MIDDLE AGED; PRIMARY CELL CULTURE; PTERYGIUM; SIGNAL TRANSDUCTION; TRANSCRIPTOME;

EID: 84862559772     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039359     Document Type: Article

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