Distinct gene subsets in pterygia formation and recurrence: Dissecting complex biological phenomenon using genome wide expression data

BMC Medical Genomics

Volumn 2, Issue , 2009, Pages

  Tong, Louis ^a   Chew, Jaime ^a   Yang, Henry ^b   Ang, Leonard Pk ^a,c,d   Tan, Donald Th ^a,c,d   Beuerman, Roger W ^a,d  

^a SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c SINGAPORE NATIONAL EYE CENTRE   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BETA MICROSEMINOPROTEIN; COLLAGEN TYPE 1; CYTOKERATIN 12; CYTOKERATIN 6; FIBRONECTIN; GENE PRODUCT; LEUKOSIALIN; PROLINE; STRUCTURAL PROTEIN; TEAR PROTEIN;

ADULT; ARTICLE; BIOLOGICAL ACTIVITY; CELL ADHESION; CELL MOTILITY; CONJUNCTIVA; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; EPITHELIUM; EYE SURGERY; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LIQUID CHROMATOGRAPHY; MALE; MOLECULE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PTERYGIUM; RECURRENT DISEASE; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA; UNINDEXED SEQUENCE; UPREGULATION; WESTERN BLOTTING;

ANIMALIA;

EID: 65349136428     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/1755-8794-2-14     Document Type: Article

References (33)

1. Determination of stromal signatures in breast carcinoma. RB West DS Nuyten S Subramanian TO Nielsen CL Corless, PLoS Biol 2005 3 e187 15869330 10.1371/journal.pbio.0030187 (Pubitemid 41032219)
2. Frequency and risk factors for pterygium in the Barbados Eye Study. R Luthra BB Nemesure SY Wu SH Xie MC Leske, Arch Ophthalmol 2001 119 1827 1832 11735795 (Pubitemid 33139615)
3. Pterygium in aged population in Doumen County, China. K Wu M He J Xu S Li, Yan Ke Xue Bao 2002 18 181 184 15510751
4. Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases. N Di Girolamo J Chui MT Coroneo D Wakefield, Prog Retin Eye Res 2004 23 195 228 10.1016/j.preteyeres.2004.02.002 15094131 (Pubitemid 38496401)
5. Pterygia pathogenesis: corneal invasion by matrix metalloproteinase expressing altered limbal epithelial basal cells. N Dushku MK John GS Schultz TW Reid, Arch Ophthalmol 2001 119 695 706 11346397 (Pubitemid 32417376)
6. Oxidative stress in pterygium: relationship between p53 and 8-hydroxydeoxyguanosine. MT Perra C Maxia A Corbu L Minerba P Demurtas, Mol Vis 2006 12 1136 1142 17093398 (Pubitemid 44480566)
7. Angiogenesis in pterygium: study of microvessel density, vascular endothelial growth factor, and thrombospondin-1. M Aspiotis E Tsanou S Gorezis E Ioachim A Skyrlas, Eye 2007 21 1095 1101 10.1038/sj.eye.6702495 16823458 (Pubitemid 47263760)
8. Glutathione transferase (class pi) and tissue transglutaminase (Tgase C) expression in pterygia. YJ Kim ES Park KY Song SC Park JC Kim, Korean J Ophthalmol 1998 12 6 13 9753945
9. Flow cytometry measurements of DNA content in primary and recurrent pterygia. DT Tan YP Liu L Sun, Invest Ophthalmol Vis Sci 2000 41 1684 1686 10845586 (Pubitemid 30354337)
10. Apoptosis and apoptosis related gene expression in normal conjunctiva and pterygium. DT Tan WY Tang YP Liu HS Goh DR Smith, Br J Ophthalmol 2000 84 212 216 10655200 10.1136/bjo.84.2.212 (Pubitemid 30251668)
11. The involvement of adult stem cells originated from bone marrow in the pathogenesis of pterygia. YS Song YH Ryu SR Choi JC Kim, Yonsei Med J 2005 46 687 692 16259068 (Pubitemid 41804745)
12. Hyperexpression of low-density lipoprotein receptors and hydroxy-methylglutaryl-coenzyme A-reductase in human pinguecula and primary pterygium. E Peiretti S Dessi M Putzolu M Fossarello, Invest Ophthalmol Vis Sci 2004 45 3982 3985 10.1167/iovs.04-0176 15505045 (Pubitemid 39411150)
13. Mast cells in pterygium: number and phenotype. T Nakagami A Murakami S Okisaka N Ebihara, Jpn J Ophthalmol 1999 43 75 79 10.1016/S0021-5155(98)00069-0 10340786 (Pubitemid 29225327)
14. The pathogenesis of pterygia. MT Coroneo N Di Girolamo D Wakefield, Curr Opin Ophthalmol 1999 10 282 288 10.1097/00055735-199908000-00011 10621537 (Pubitemid 30339430)
15. Expression of p63 and p16 in primary and recurrent pterygia. FS Ramalho C Maestri LN Ramalho A Ribeiro-Silva E Romao, Graefes Arch Clin Exp Ophthalmol 2006 244 1310 1314 10.1007/s00417-006-0287-5 16523297 (Pubitemid 44463470)
16. Microarray and protein analysis of human pterygium. M John-Aryankalayil N Dushku CJ Jaworski CA Cox G Schultz, Mol Vis 2006 12 55 64 16446702 (Pubitemid 43137827)
17. Overexpression of Insulin-like growth factor-binding protein-2 in pterygium body fibroblasts. A Solomon M Grueterich DQ Li D Meller SB Lee, Invest Ophthalmol Vis Sci 2003 44 573 580 10.1167/iovs.01-1185 12556385 (Pubitemid 36159701)
18. Characterisation of human tear proteins using high-resolution mass spectrometry. L Zhou RW Beuerman Y Foo S Liu LP Ang, Ann Acad Med Singapore 2006 35 400 407 16865190 (Pubitemid 44379494)
19. Expression of insulin-like growth factor binding protein-3 in pterygium tissue. YW Wong J Chew H Yang DT Tan R Beuerman, Br J Ophthalmol 2006 90 769 772 10.1136/bjo.2005.087486 16488932 (Pubitemid 43835499)
20. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. RA Irizarry B Hobbs F Collin YD Beazer-Barclay KJ Antonellis, Biostatistics 2003 4 249 264 10.1093/biostatistics/4.2.249 12925520
21. A segmental nearest neighbor normalization and gene identification method gives superior results for DNA-array analysis. H Yang H Haddad C Tomas K Alsaker ET Papoutsakis, Proc Natl Acad Sci USA 2003 100 1122 1127 12529501 10.1073/pnas.0237337100 (Pubitemid 36183966)
22. Significance analysis of microarrays applied to the ionizing radiation response. VG Tusher R Tibshirani G Chu, Proc Natl Acad Sci USA 2001 98 5116 5121 11309499 10.1073/pnas.091062498 (Pubitemid 32397092)
23. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. A Subramanian P Tamayo VK Mootha S Mukherjee BL Ebert, Proc Natl Acad Sci USA 2005 102 15545 15550 16199517 10.1073/pnas.0506580102 (Pubitemid 41528093)
24. Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. KJ Livak SJ Flood J Marmaro W Giusti K Deetz, PCR Methods Appl 1995 4 357 362 7580930
25. Trefoil factor family mRNA and protein expression in pterygium. PO Lafontaine M Arnal N Buron E Solary AM Bron, Int J Oncol 2005 27 997 1003 16142316
26. Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia. AS Haider SB Peters H Kaporis I Cardinale J Fei, J Invest Dermatol 2006 126 869 881 10.1038/sj.jid.5700157 16470182
27. Beta microseminoprotein is not a prostate-specific protein. Its identification in mucous glands and secretions. H Weiber C Andersson A Murne G Rannevik C Lindstrom, Am J Pathol 1990 137 593 603 2205099 (Pubitemid 20280989)
28. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. HY Chang JB Sneddon AA Alizadeh R Sood RB West, PLoS Biol 2004 2 E7 14737219 10.1371/journal.pbio. 0020007 (Pubitemid 39234559)
29. The transcriptional program in the response of human fibroblasts to serum. VR Iyer MB Eisen DT Ross G Schuler T Moore, Science 1999 283 83 87 10.1126/science.283.5398.83 9872747 (Pubitemid 29044852)
30. Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan. AF Muro AK Chauhan S Gajovic A Iaconcig F Porro, J Cell Biol 2003 162 149 160 12847088 10.1083/jcb.200212079 (Pubitemid 36859542)
31. Roles of osteonectin in the migration of breast cancer cells into bone. DA Campo McKnight DM Sosnoski JE Koblinski CV Gay, J Cell Biochem 2006 97 288 302 10.1002/jcb.20644 16173048 (Pubitemid 43167146)
32. Decreased expression of prostatic secretory protein PSP94 in prostate cancer. AY Liu RC Bradner RL Vessella, Cancer Lett 1993 74 91 99 10.1016/0304-3835(93)90049-F 7506990 (Pubitemid 23331052)
33. Trefoil factors: initiators of mucosal healing. D Taupin DK Podolsky, Nat Rev Mol Cell Biol 2003 4 721 732 10.1038/nrm1203 14506475 (Pubitemid 37082187)