Targeting of ICAM-1 on vascular endothelium under static and shear stress conditions using a liposomal Gd-based MRI contrast agent

Journal of Nanobiotechnology

Volumn 10, Issue , 2012, Pages

  Paulis, Leonie E M ^a   Jacobs, Igor ^a   van den Akker, Nynke M ^b   Geelen, Tessa ^a   Molin, Daniel G ^b   Starmans, Lucas W E ^a   Nicolay, Klaas ^a   Strijkers, Gustav J ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Endothelium; ICAM 1; Leukocyte; Liposome; Molecular MRI; Shear stress

Indexed keywords

CARDIO-VASCULAR DISEASE; CONTRAST AGENT; ENDOTHELIUM; FLUORESCENCE IMAGING; FUNCTIONALIZED; ICAM-1; ICAM-1 EXPRESSION; IN-VITRO; IN-VIVO; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTE; MRI CONTRAST AGENTS; MULTI-MODAL; MYOCARDIAL INFARCTION; NON-INVASIVE MONITORING; PHYSIOLOGICAL FLOW; PRO-INFLAMMATORY STIMULI; RELAXIVITY; STRESS CONDITION; STRONG BINDING; UP-REGULATION; VASCULAR ENDOTHELIUM;

BLOOD VESSELS; CELL ADHESION; DISEASES; ENDOTHELIAL CELLS; GADOLINIUM; MAGNETIC RESONANCE IMAGING; MOLECULAR IMAGING; PARAMAGNETISM; PATHOLOGY; SHEAR STRESS;

LIPOSOMES;

GADOLINIUM; GADOLINIUM 1,4,7,10 TETRAAZACYCLODODECANE N,N',N'',N''' TETRAACETIC ACID 1,2 DISTREAOYL GLYCERO 3 PHOSPHOETHANOLAMINE; INTERCELLULAR ADHESION MOLECULE 1; LIPOSOME; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; FLUORESCENCE; FOLLOW UP; IN VITRO STUDY; LEUKOCYTE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN EXPRESSION; SHEAR STRESS; UPREGULATION; VASCULAR ENDOTHELIUM;

ANIMALS; CELL LINE; CONTRAST MEDIA; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; GADOLINIUM; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTES; LIPOSOMES; MAGNETIC RESONANCE IMAGING; MICE; MOLECULAR IMAGING; SHEAR STRENGTH; STRESS, MECHANICAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862327609     PISSN: None     EISSN: 14773155     Source Type: Journal    
DOI: 10.1186/1477-3155-10-25     Document Type: Article

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