A high relaxivity Gd(III)DOTA-DSPE-based liposomal contrast agent for magnetic resonance imaging

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 72, Issue 2, 2009, Pages 397-404

  Hak, Sjoerd ^a   Sanders, Honorius M H F ^a   Agrawal, Prashant ^a   Langereis, Sander ^b   Grüll, Holger ^a,b   Keizer, Henk M ^c   Arena, Francesca ^d   Terreno, Enzo ^d   Strijkers, Gustav J ^a   Nicolay, Klaas ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b PHILIPS RESEARCH LABORATORIES   (Netherlands)

^c SyMO Chem   (Netherlands)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

Contrast agent; cryo TEM; Gadolinium; Gd(III)DOTA DSPE; Liposomes; Longitudinal relaxivity; Magnetic resonance imaging; Molecular imaging; Transmetallation

Indexed keywords

1,2 DISTEAROYL SN GLYCERO 3 PHOSPHOETHANOLAMINE; CONTRAST MEDIUM; GADOTERIC ACID; LIPOSOME; MOLECULAR MARKER; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; BIOCOMPATIBILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG STABILITY; DRUG SYNTHESIS; DRUG TARGETING; IN VITRO STUDY; INCUBATION TIME; METALLATION; MOLECULAR IMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING;

CONTRAST MEDIA; LIPOSOMES; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; ORGANOMETALLIC COMPOUNDS; PHOSPHATIDYLETHANOLAMINES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 67349146757     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.09.017     Document Type: Article

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