Dual targeting improves microbubble contrast agent adhesion to VCAM-1 and P-selectin under flow

Journal of Controlled Release

Volumn 140, Issue 2, 2009, Pages 100-107

  Ferrante, E A ^a   Pickard, J E ^a   Rychak, J ^b   Klibanov, A ^b   Ley, K ^c  

^a University of Virginia   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

Microbubbles; P selectin; Targeting; Ultrasound contrast; VCAM 1

Indexed keywords

MICROBUBBLES; P-SELECTIN; TARGETING; ULTRASOUND CONTRAST; VCAM-1;

ACOUSTIC WAVES; ADHESION; BLOOD VESSELS; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; SHEAR STRESS; STRENGTH OF MATERIALS; ULTRASONIC APPLICATIONS; ULTRASONICS;

ULTRASONIC IMAGING;

ECHO CONTRAST MEDIUM; FLUOROCARBON; MACROGOL; PADGEM PROTEIN; PHOSPHOLIPID; VASCULAR CELL ADHESION MOLECULE 1;

ADHESION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FLOW CYTOMETRY; FLUORESCENCE; IMAGING SYSTEM; MICROBUBBLE; MOLECULAR IMAGING; PRIORITY JOURNAL; PROTEIN TARGETING; RADIOIODINATION; SHEAR STRESS;

ANIMALS; ANTIBODIES, MONOCLONAL; ATHEROSCLEROSIS; BIOTIN; CONTRAST MEDIA; FLUOROCARBONS; IODINE RADIOISOTOPES; MICE; MICROBUBBLES; OLIGOSACCHARIDES; P-SELECTIN; PERFUSION; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; PROTEIN BINDING; RECOMBINANT PROTEINS; STREPTAVIDIN; STRESS, MECHANICAL; VASCULAR CELL ADHESION MOLECULE-1;

EID: 70350621516     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.08.001     Document Type: Article

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