A possible novel anti-inflammatory mechanism for the pharmacological prolyl hydroxylase inhibitor 3,4-dihydroxybenzoate: Implications for use as a therapeutic for Parkinson's disease

Parkinson's Disease

Volumn , Issue , 2012, Pages

  Chinta, Shankar J ^a   Rajagopalan, Subramanian ^a   Ganesan, Abirami ^a   Andersen, Julie K ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE SYNTHASE; PROTOCATECHUIC ACID; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG SCREENING; ENZYME INHIBITION; ENZYME REGULATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROGLIA; MOUSE; NERVE CELL INHIBITION; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; UPREGULATION;

EID: 84862294186     PISSN: None     EISSN: 20420080     Source Type: Journal    
DOI: 10.1155/2012/364684     Document Type: Article

References (49)

1. Andersen J. K., Oxidative stress in neurodegeneration: cause or consequence? Nature Medicine 2004 10 supplement S18 S25
2. Schapira A. H., Jenner P., Etiology and pathogenesis of Parkinson's disease Movement Disorders 2011 26 6 1049 1055
3. Thomas B., Beal M. F., Parkinson's disease Human Molecular Genetics 2007 16 2 R183 R194
4. Gupta A., Dawson V. L., Dawson T. M., What causes cell death in Parkinson's disease? Annals of Neurology 2008 64 supplement 2 S3 S15
5. Minghetti L., Role of inflammation in neurodegenerative diseases Current Opinion in Neurology 2005 18 3 315 321 (Pubitemid 40813762)
6. Kuhn W., Mller T., Nastos I., Poehlau D., The neuroimmune hypothesis in Parkinson's disease Reviews in the Neurosciences 1997 8 1 29 34 (Pubitemid 27354656)
7. McGeer P. L., Itagaki S., Boyes B. E., McGeer E. G., Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains Neurology 1988 38 8 1285 1291
8. Orr C. F., Rowe D. B., Halliday G. M., An inflammatory review of Parkinson's disease Progress in Neurobiology 2002 68 5 325 340 (Pubitemid 36071510)
9. Tansey M. G., McCoy M. K., Frank-Cannon T. C., Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention Experimental Neurology 2007 208 1 1 25 (Pubitemid 47603240)
10. Hirsch E. C., Hunot S., Neuroinflammation in Parkinson's disease: a target for neuroprotection? The Lancet Neurology 2009 8 4 382 397
11. Knott C., Stern G., Wilkin G. P., Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2 Molecular and Cellular Neuroscience 2000 16 6 724 739 (Pubitemid 32062060)
12. Kreutzberg G. W., Microglia: a sensor for pathological events in the CNS Trends in Neurosciences 1996 19 8 312 318 (Pubitemid 26349059)
13. Qian L., Flood P. M., Hong J. S., Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy Journal of Neural Transmission 2010 117 8 971 979
14. Lee J. K., Tran T., Tansey M. G., Neuroinflammation in Parkinson's disease Journal of Neuroimmune Pharmacology 2009 4 4 419 429
15. Liu B., Hong J. S., Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention Journal of Pharmacology and Experimental Therapeutics 2003 304 1 1 7 (Pubitemid 36008905)
16. Epstein A. C. R., Gleadle J. M., McNeill L. A., Hewitson K. S., O'Rourke J., Mole D. R., Mukherji M., Metzen E., Wilson M. I., Dhanda A., Tian Y. M., Masson N., Hamilton D. L., Jaakkola P., Barstead R., Hodgkin J., Maxwell P. H., Pugh C. W., Schofield C. J., Ratcliffe P. J., C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation Cell 2001 107 1 43 54 (Pubitemid 32972036)
17. Hirsil M., Koivunen P., Gnzler V., Kivirikko K. I., Myllyharju J., Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor The Journal of Biological Chemistry 2003 278 33 30772 30780 (Pubitemid 36994584)
18. Semenza G. L., HIF-1, O 2, and the 3 PHDs: how animal cells signal hypoxia to the nucleus Cell 2001 107 1 1 3 (Pubitemid 32972030)
19. Hurn P. D., Koehler R. C., Blizzard K. K., Traystman R. J., Beckman J. S., Deferoxamine reduces early metabolic failure associated with severe cerebral ischemic acidosis in dogs Stroke 1995 26 4 688 695
20. Siddiq A., Ayoub I. A., Chavez J. C., Aminova L., Shah S., LaManna J. C., Patton S. M., Connor J. R., Cherny R. A., Volitakis I., Bush A. I., Langsetmo I., Seeley T., Gunzler V., Ratan R. R., Hypoxia-inducible factor prolyl 4-hydroxylase inhibition: a target for neuroprotection in the central nervous system The Journal of Biological Chemistry 2005 280 50 41732 41743 (Pubitemid 41832236)
21. Lee D. W., Rajagopalan S., Siddiq A., Gwiazda R., Yang L., Beal M. F., Ratan R. R., Andersen J. K., Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. Model for the potential involvement of the hypoxia-unducible factor pathway in Parkinson disease The Journal of Biological Chemistry 2009 284 42 29065 29076
22. Blasi E., Barluzzi R., Bocchini V., Mazzolla R., Bistoni F., Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus Journal of Neuroimmunology 1990 27 2-3 229 237 (Pubitemid 20146292)
23. Chinta S. J., Rajagopalan S., Butterfield D. A., Andersen J. K., In vitro and in vivo neuroprotection by -glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease Neuroscience Letters 2006 402 1-2 137 141 (Pubitemid 43766441)
24. Chinta S. J., Rane A., Poksay K. S., Bredesen D. E., Andersen J. K., Rao R. V., Coupling endoplasmic reticulum stress to the cell death program in dopaminergic cells: effect of paraquat NeuroMolecular Medicine 2008 10 4 333 342
25. Sriram K., Miller D. B., O'Callaghan J. P., Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor- Journal of Neurochemistry 2006 96 3 706 718
26. Kaku K., Shikimi T., Kamisaki Y., Shinozuka K., Ishino H., Okunishi H., Takaori S., Elevation of striatal interleukin-6 and serum corticosterone contents in MPTP-treated mice Clinical and Experimental Pharmacology and Physiology 1999 26 9 680 683 (Pubitemid 29437238)
27. Peng J., Mao X. O., Stevenson F. F., Hsu M., Andersen J. K., The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway The Journal of Biological Chemistry 2004 279 31 32626 32632 (Pubitemid 39014720)
28. Wang S., Wang H., Guo H., Kang L., Gao X., Hu L., Neuroprotection of Scutellarin is mediated by inhibition of microglial inflammatory activation Neuroscience 2011 185 150 160
29. Mallajosyula J. K., Kaur D., Chinta S. J., Rajagopalan S., Rane A., Nicholls D. G., Di Monte D. A., Macarthur H., Andersen J. K., MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology PLoS One 2008 3 2
30. Jung J. S., Shin J. A., Park E. M., Lee J. E., Kang Y. S., Min S. W., Kim D. H., Hyun J. W., Shin C. Y., Kim H. S., Anti-inflammatory mechanism of ginsenoside Rh1 in lipopolysaccharide- stimulated microglia: critical role of the protein kinase A pathway and hemeoxygenase-1 expression Journal of Neurochemistry 2010 115 6 1668 1680
31. Paine A., Eiz-Vesper B., Blasczyk R., Immenschuh S., Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential Biochemical Pharmacology 2010 80 12 1895 1903
32. Long-Smith C. M., Sullivan A. M., Nolan Y. M., The influence of microglia on the pathogenesis of Parkinson's disease Progress in Neurobiology 2009 89 3 277 287
33. Li F., Zhu S., Wu C., Yan C., Liu Y., Shugan L., Neuroinflammation and cell therapy for Parkinson's disease Frontiers in Bioscience 2011 3 1407 1420
34. Tansey M. G., Goldberg M. S., Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention Neurobiology of Disease 2010 37 3 510 518
35. Bhat N. R., Zhang P., Lee J. C., Hogan E. L., Extracellular signal-regulated kinase and p38 subgroups of mitogen- activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor- gene expression in endotoxin-stimulated primary glial cultures Journal of Neuroscience 1998 18 5 1633 1641 (Pubitemid 28103071)
36. Xie Z., Smith C. J., Van Eldik L. J., glias induce neuron death via MAP kinase signaling pathways involving JNK and p38 Glia 2004 45 2 170 179 (Pubitemid 38196993)
37. Koistinaho M., Kettunen M. I., Goldsteins G., Keinnen R., Salminen A., Ort M., Bures J., Liu D., Kauppinen R. A., Higgins L. S., Koistinaho J., -amyloid precursor protein transgenic mice that harbor diffuse A deposits but do not form plaques show increased ischemic vulnerability: role of inflammation Proceedings of the National Academy of Sciences of the United States of America 2002 99 3 1610 1615 (Pubitemid 34136540)
38. Shibata H., Katsuki H., Nishiwaki M., Kume T., Kaneko S., Akaike A., Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin Journal of Neurochemistry 2003 86 5 1201 1212 (Pubitemid 37022196)
39. Iravani M. M., Kashefi K., Mander P., Rose S., Jenner P., Involvement of inducible nitric oxide synthase in inflammation-induced dopaminergic neurodegeneration Neuroscience 2002 110 1 49 58 (Pubitemid 34214759)
40. Liberatore G. T., Jackson-Lewis V., Vukosavic S., Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease Nature Medicine 1999 5 12 1403 1409
41. Nowis D., Bugajski M., Winiarska M., Bil J., Szokalska A., Salwa P., Issat T., Was H., Jozkowicz A., Dulak J., Stoklosa T., Golab J., Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice BMC Cancer 2008 8, article 197
42. Ryter S. W., Alam J., Choi A. M. K., Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications Physiological Reviews 2006 86 2 583 650
43. Scott J. R., Chin B. Y., Bilban M. H., Otterbein L. E., Restoring HOmeostasis: is heme oxygenase-1 ready for the clinic? Trends in Pharmacological Sciences 2007 28 5 200 205 (Pubitemid 46661005)
44. Jeong G. S., Li B., Lee D. S., Byun E., An R. B., Pae H. O., Chung H. T., Youn K. H., Kim Y. C., Lavandulyl flavanones from Sophora flavescens protect mouse hippocampal cells against glutamate-induced neurotoxicity via the induction of heme oxygenase-1 Biological and Pharmaceutical Bulletin 2008 31 10 1964 1967
45. Lu D. Y., Tsao Y. Y., Leung Y. M., Su K. P., Docosahexaenoic acid suppresses neuroinflammatory responses and induces heme oxygenase-1 expression in BV-2 microglia: implications of antidepressant effects for omega-3 fatty acids Neuropsychopharmacology 2010 35 11 2238 2248
46. Min K. J., Yang M. S., Kim S. U., Jou I., Joe E. H., Astrocytes induce hemeoxygenase-1 expression in microglia: a feasible mechanism for preventing excessive brain inflammation Journal of Neuroscience 2006 26 6 1880 1887 (Pubitemid 43237001)
47. Kitamura Y., Kakimura J. I., Matsuoka Y., Yasuyuki Nomura, Gebicke-Haerter P. J., Taniguchi T., Activators of peroxisome proliferator-activated receptor- (PPAR ) inhibit inducible nitric oxide synthase expression but increase heme oxygenase-1 expression in rat glial cells Neuroscience Letters 1999 262 2 129 132 (Pubitemid 29130305)
48. Tsoyi K., Kim H. J., Shin J. S., Kim D. H., Cho H. J., Lee S. S., Ahn S. K., Yun-Choi H. S., Lee J. H., Seo H. G., Chang K. C., HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride Cellular Signalling 2008 20 10 1839 1847
49. Vareille M., Rannou F., Thélier N., Glasser A. L., Sablet T. D., Martin C., Gobert A. P., Heme oxygenase-1 is a critical regulator of nitric oxide production In Enterohemorrhagic Escherichia coli -infected human enterocytes1 The Journal of Immunology 2008 180 8 5720 5726