Zebrafish Parla- and Parlb-deficiency affects dopaminergic neuron patterning and embryonic survival

Journal of Neurochemistry

Volumn 122, Issue 1, 2012, Pages 196-207

  Noble, Sandra ^a   Ismail, Abid ^a   Godoy, Rafael ^a   Xi, Yanwei ^a   Ekker, Marc ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

dopaminergic neurons; morpholino knockdown; Parkinson's disease; parl; pink1; zebrafish

Indexed keywords

MESSENGER RNA; PRESENILIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL DENSITY; CONTROLLED STUDY; DIENCEPHALON; DOPAMINERGIC NERVE CELL; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; EMBRYO SURVIVAL; FISH GENETICS; GENE; GENE FUNCTION; GENE LOCUS; LARVA; MITOCHONDRION; MORTALITY; NERVE DEGENERATION; NONHUMAN; PARKINSON DISEASE; PHENOTYPE; PRESENILIN ASSOCIATED RHOMBOID LIKE GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SURVIVAL; SYNTENY; ZEBRA FISH;

ACRIDINE ORANGE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BODY PATTERNING; CELL DEATH; CLONING, MOLECULAR; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINERGIC NEURONS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; HUMANS; LARVA; METALLOPROTEASES; MITOCHONDRIAL PROTEINS; MORPHOLINOS; PROTEIN KINASES; RNA, MESSENGER; SEQUENCE ALIGNMENT; TYROSINE 3-MONOOXYGENASE; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO; VERTEBRATA;

EID: 84862237466     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07758.x     Document Type: Article

References (39)

1. Anichtchik O. V., Diekmann H., Fleming A., Roach A., Goldsmith P., and, Rubinsztein D. C., (2008) Loss of PINK1 function affects development and results in neurodegeneration in zebrafish. J. Neurosci. 28, 8199-8207.
2. Baulac S., Lu H., Strahle J., et al. (2009) Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains. Mol. Neurodegener. 4, 12.
3. Bretaud S., Allen C., Ingham P., and, Bandmann O., (2007) p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease. J. Neurochem. 100, 1626-1635. (Pubitemid 46376201)
4. Cipolat S., Rudka T., Hartmann D., et al. (2006) Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling. Cell 126, 163-175.
5. Cookson M. R., (2005) The biochemistry of Parkinson's disease. Annu. Rev. Biochem. 74, 29-52. (Pubitemid 40995500)
6. Dauer W., and, Przedborski S., (2003) Parkinson's disease: mechanisms and models. Neuron 39, 889-909. (Pubitemid 37130207)
7. Deas E., Plun-Favreau H., Gandhi S., et al. (2011) PINK1 cleavage at position A103 by the mitochondrial protease PARL. Hum. Mol. Genet. 20, 867-879.
8. Farrer M. J., (2006) Genetics of Parkinson disease: paradigm shifts and future prospects. Nature. Rev. Genet. 7, 306-318.
9. Fett M. E., Pilsl A., Paquet D., van Bebber F., Haass C., Tatzelt J., Schmid B., and, Winklhofer K. F., (2010) Parkin is protective against proteotoxic stress in a transgenic zebrafish model. PLoS ONE 5, e11783.
10. Flinn L., Mortiboys H., Volkmann K., Koster R. W., Ingham P. W., and, Bandmann O., (2009) Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio). Brain 132, 1613-1623.
11. Frezza C., Cipolat S., Martins de Brito O., et al. (2006) OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion. Cell 126, 177-189.
12. Greene A. W., Grenier K., Aguileta M. A., Muise S., Farazifard R., Haque M. E., McBride H. M., Park D. S., and, Fon E. A,. (2012) Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. EMBO Rep. 13, 378-385.
13. Haque M. E., Thomas K. J., D'Souza C., et al. (2008) Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proc. Natl Acad. Sci. USA 105, 1716-1721. (Pubitemid 351346580)
14. Herlan M., Vogel F., Bornhovd C., Neupert W., and, Reichert A. S., (2003) Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA. J. Biol. Chem. 278, 27781-27788. (Pubitemid 36899969)
15. Holzschuh J., Ryu S., Aberger F., and, Driever W., (2001) Dopamine transporter expression distinguishes dopaminergic neurons form other catecholaminergic neurons in the developing zebrafish embryo. Mech. Dev. 10, 1.
16. Jeyaraju D. V., Xu L., Letellier M. C., Bandaru S., Zunino R., Berg E. A., McBride H. M., and, Pellegrini L., (2006) Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology. Proc. Natl Acad. Sci. USA 103, 18562-18567. (Pubitemid 44913450)
17. Jin S. M., Lazarou M., Wang C., Kane L. A., Narendra D. P., and, Youle R. J., (2010) Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J. Cell Biol. 191, 933-942.
18. Kimmel C. B., Ballard W. W., Kimmel S. R., Ullmann B., and, Schilling T. F., (1995) Stages of embryonic development of the zebrafish. Dev. Dyn. 203, 253-310.
19. Koonin E. V., Makarova K. S., Rogozin I. B., Davidovic L., Letellier M. C., and, Pellegrini L., (2003) The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers. Genome Biol. 4, R19.
20. Ma P. M., (2003) Catecholaminergic systems in the zebrafish IV. Organization and projection pattern of dopaminergic neurons in the diencephalon. J. Comp. Neurol. 460, 13-37. (Pubitemid 36438275)
21. McQuibban G., Saurya S., and, Freeman M., (2003) Mitochondrial membrane remodelling regulated by a conserved rhomboid protease. Nature 423, 537-541. (Pubitemid 36648577)
22. McQuibban G. A., Lee J. R., Zheng L., Juusola M., and, Freeman M., (2006) Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal function. Curr. Biol. 16, 982-989. (Pubitemid 43728227)
23. Pellegrini L., Passer B. J., Canelles M., Lefterov I., Ganjei J. K., Fowlkes B. J., Koonin E. V., and, D'Adamio L., (2001) PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of presenilin-1 and -2. J. Alzheimer's Dis. 3, 181-190. (Pubitemid 32566518)
24. Postlethwait J., Amores A., Cresko W., Singer A., and, Yan Y. L., (2004) Subfunction partitioning, the teleost radiation and the annotation of the human genome. Trends Genet. 20, 481-490. (Pubitemid 39201068)
25. Ren G., Xin S., Li S., Zhong H., and, Lin S., (2011) Disruption of LRRK2 does not cause specific loss of dopaminergic neurons in zebrafish. PLoS ONE 6, e20630.
26. Rink E., and, Wullimann M. F., (2002) Development of the catecholaminergic system in the early zebrafish brain: an immunohistochemical study. Brain Res. Dev. Brain Res. 137, 89-100. (Pubitemid 34786640)
27. Robu M. E., Larson J. D., Nasevicius A., Beiraghi S., Brenner C., Farber S. A., and, Ekker S. C., (2007) p53 activation by knockdown technologies. PLoS Genet. 3, e78.
28. Sallinen V., Kolehmainen J., Priyadarshini M., Toleikyte G., Chen Y. C., and, Panula P., (2010) Dopaminergic cell damage and vulnerability to MPTP in Pink1 knockdown zebrafish. Neurobiol. Dis. 40, 93-101.
29. Sheng D., Qu D., Kwok K. H., et al. (2010) Deletion of the WD40 domain of LRRK2 in Zebrafish causes Parkinsonism-like loss of neurons and locomotive defect. PLoS Genet. 6, e1000914.
30. Shi G., Lee J. R., Grimes D. A., et al. (2011) Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease. Hum. Mol. Genet. 20, 1966-1974.
31. Sik A., Passer B. J., Koonin E. V., and, Pellegrini L., (2004) Self-regulated cleavage of the mitochondrial intramembrane-cleaving protease PARL yields Pbeta, a nuclear-targeted peptide. J. Biol. Chem. 279, 15323-15329. (Pubitemid 38618930)
32. Tay T. L., Ronneberger O., Ryu S., Nitschke R., and, Driever W., (2011) Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nat. Commun. 2, 171.
33. Thisse C., and, Thisse B., (2008) High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat. Protoc. 3, 59-69.
34. Westerfield M., (2000) The Zebrafish Book. University of Oregon Press, Eugene.
35. Whitworth A. J., Lee J. R., Ho V. M., Flick R., Chowdhury R., and, McQuibban G. A,. (2008) Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin. Dis. Model. Mech. 1, 168-174; discussion 173.
36. Xi Y., Ryan J., Noble S., Yu M., Yilbas A. E., and, Ekker M., (2010) Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function. Eur. J. Neurosci. 31, 623-633.
37. Xi Y., Noble S., and, Ekker M., (2011a) Modeling neurodegeneration in zebrafish. Curr. Neurol. Neurosci. Rep. 11, 274-282.
38. Xi Y., Yu M., Godoy R., Hatch G., Poitras L., and, Ekker M,. (2011b) Transgenic zebrafish expressing GFP in dopaminergic neurons of the ventral diencephalon. Dev. Dyn. 240, 2539-2547.
39. Yamamoto K., Ruuskanen J. O., Wullimann M. F., and, Vernier P., (2011) Differential expression of dopaminergic cell markers in the adult zebrafish forebrain. J. Comp. Neurol. 519, 576-598.