Disruption of lrrk2 does not cause specific loss of dopaminergic neurons in zebrafish

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Ren, Guiqi ^a   Xin, Shengchang ^a   Li, Song ^a   Zhong, Hanbing ^a   Lin, Shuo ^a,b  

^a PEKING UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE RICH REPEAT KINASE 2; MESSENGER RNA; DOPAMINE; LRRK2 PROTEIN, ZEBRAFISH; PRIMER DNA; PROTEIN SERINE THREONINE KINASE; ZEBRAFISH PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LOSS; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO CELL; GENE DISRUPTION; GENE FUNCTION; GENE IDENTIFICATION; GENE TARGETING; IN SITU HYBRIDIZATION; LOSS OF FUNCTION MUTATION; MOLECULAR PROBE; NONHUMAN; PARKINSON DISEASE; PHENOTYPE; PROTEIN DOMAIN; RNA SPLICING; ZEBRA FISH; ANIMAL; CYTOLOGY; GENE SILENCING; GENETICS; METABOLISM; NERVE CELL; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VALIDATION STUDY;

DANIO RERIO;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; DOPAMINE; GENE KNOCKDOWN TECHNIQUES; IN SITU HYBRIDIZATION; NEURONS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 79959242887     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020630     Document Type: Article

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