-
1
-
-
0035415869
-
Chemical genetic approaches for the elucidation of signaling pathways
-
10.1016/S1367-5931(00)00215-5 11470597
-
Chemical genetic approaches for the elucidation of signaling pathways. Alaimo PJ, Shogren-Knaak MA, Shokat KM, Curr Opin Chem Biol 2001 5 360 367 10.1016/S1367-5931(00)00215-5 11470597
-
(2001)
Curr Opin Chem Biol
, vol.5
, pp. 360-367
-
-
Alaimo, P.J.1
Shogren-Knaak, M.A.2
Shokat, K.M.3
-
2
-
-
0036462476
-
Chemical genomics in the global study of protein functions
-
10.1016/S1359-6446(01)02118-3 11815236
-
Chemical genomics in the global study of protein functions. Zheng XF, Chan TF, Drug Discov Today 2002 7 197 205 10.1016/S1359-6446(01)02118-3 11815236
-
(2002)
Drug Discov Today
, vol.7
, pp. 197-205
-
-
Zheng, X.F.1
Chan, T.F.2
-
3
-
-
0024472603
-
A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase
-
10.1038/341758a0 2477715
-
A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. Harding MW, Galat A, Uehling DE, Schreiber SL, Nature 1989 341 758 760 10.1038/341758a0 2477715
-
(1989)
Nature
, vol.341
, pp. 758-760
-
-
Harding, M.W.1
Galat, A.2
Uehling, D.E.3
Schreiber, S.L.4
-
4
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
10.1016/0092-8674(91)90124-H 1715244
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Liu J, Farmer JD, Lane WS, Friedman J, Weissman I, Schreiber SL, Cell 1991 66 807 815 10.1016/0092-8674(91)90124-H 1715244
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer, J.D.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
5
-
-
0025871394
-
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A
-
10.1038/352803a0 1715516
-
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Flanagan WM, Corthesy B, Bram RJ, Crabtree GR, Nature 1991 352 803 807 10.1038/352803a0 1715516
-
(1991)
Nature
, vol.352
, pp. 803-807
-
-
Flanagan, W.M.1
Corthesy, B.2
Bram, R.J.3
Crabtree, G.R.4
-
6
-
-
0028318159
-
Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression
-
8119981
-
Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. Nishi K, Yoshida M, Fujiwara D, Nishikawa M, Horinouchi S, Beppu T, J Biol Chem 1994 269 6320 6324 8119981
-
(1994)
J Biol Chem
, vol.269
, pp. 6320-6324
-
-
Nishi, K.1
Yoshida, M.2
Fujiwara, D.3
Nishikawa, M.4
Horinouchi, S.5
Beppu, T.6
-
7
-
-
0033529866
-
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region
-
10.1073/pnas.96.16.9112 10430904
-
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Kudo N, Matsumori N, Taoka H, Fujiwara D, Schreiner EP, Wolff B, Yoshida M, Horinouchi S, Proc Natl Acad Sci U S A 1999 96 9112 9117 10.1073/pnas.96.16.9112 10430904
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 9112-9117
-
-
Kudo, N.1
Matsumori, N.2
Taoka, H.3
Fujiwara, D.4
Schreiner, E.P.5
Wolff, B.6
Yoshida, M.7
Horinouchi, S.8
-
8
-
-
0024996768
-
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
-
2211619
-
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. Yoshida M, Kijima M, Akita M, Beppu T, J Biol Chem 1990 265 17174 17179 2211619
-
(1990)
J Biol Chem
, vol.265
, pp. 17174-17179
-
-
Yoshida, M.1
Kijima, M.2
Akita, M.3
Beppu, T.4
-
9
-
-
0028064940
-
Inhibition of heat shock protein HSP90-pp 60v-src heteroprotein complex formation by benzoquinone ansamycins: Essential role for stress proteins in oncogenic transformation
-
10.1073/pnas.91.18.8324 8078881
-
Inhibition of heat shock protein HSP90-pp 60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation. Whitesell L, Mimnaugh EG, De Costa B, Myers CE, Neckers LM, Proc Natl Acad Sci U S A 1994 91 8324 8328 10.1073/pnas.91.18.8324 8078881
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 8324-8328
-
-
Whitesell, L.1
Mimnaugh, E.G.2
De Costa, B.3
Myers, C.E.4
Neckers, L.M.5
-
10
-
-
0031005361
-
Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent
-
10.1016/S0092-8674(00)80203-2 9108479
-
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Stebbins CE, Russo AA, Schneider C, Rosen N, Hartl FU, Pavletich NP, Cell 1997 89 239 250 10.1016/S0092-8674(00) 80203-2 9108479
-
(1997)
Cell
, vol.89
, pp. 239-250
-
-
Stebbins, C.E.1
Russo, A.A.2
Schneider, C.3
Rosen, N.4
Hartl, F.U.5
Pavletich, N.P.6
-
11
-
-
0031444238
-
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
-
10.1016/S0092-8674(00)80314-1 9230303
-
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone. Prodromou C, Roe SM, OBrien R, Ladbury JE, Piper PW, Pearl LH, Cell 1997 90 65 75 10.1016/S0092-8674(00)80314-1 9230303
-
(1997)
Cell
, vol.90
, pp. 65-75
-
-
Prodromou, C.1
Roe, S.M.2
Obrien, R.3
Ladbury, J.E.4
Piper, P.W.5
Pearl, L.H.6
-
12
-
-
17044373269
-
Finding the target after screening the phenotype
-
10.1016/S1359-6446(05)03415-X 15809197
-
Finding the target after screening the phenotype. Hart CP, Drug Discov Today 2005 10 513 519 10.1016/S1359-6446(05)03415-X 15809197
-
(2005)
Drug Discov Today
, vol.10
, pp. 513-519
-
-
Hart, C.P.1
-
13
-
-
34548128437
-
Statistical prediction of protein chemical interactions based on chemical structure and mass spectrometry data
-
10.1093/bioinformatics/btm266 17510168
-
Statistical prediction of protein chemical interactions based on chemical structure and mass spectrometry data. Nagamine N, Sakakibara Y, Bioinformatics 2007 23 2004 2012 10.1093/bioinformatics/btm266 17510168
-
(2007)
Bioinformatics
, vol.23
, pp. 2004-2012
-
-
Nagamine, N.1
Sakakibara, Y.2
-
14
-
-
67650895854
-
Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening
-
10.1371/journal.pcbi.1000397 19503826
-
Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening. Nagamine N, Shirakawa T, Minato Y, Torii K, Kobayashi H, Imoto M, Sakakibara Y, PLoS Comput Biol 2009 5 1000397 10.1371/journal.pcbi.1000397 19503826
-
(2009)
PLoS Comput Biol
, vol.5
, pp. 51000397
-
-
Nagamine, N.1
Shirakawa, T.2
Minato, Y.3
Torii, K.4
Kobayashi, H.5
Imoto, M.6
Sakakibara, Y.7
-
15
-
-
39049087313
-
Discovery of incednine as a potent modulator of the anti-apoptotic function of Bcl-xL from microbial origin
-
10.1021/ja710124p 18205364
-
Discovery of incednine as a potent modulator of the anti-apoptotic function of Bcl-xL from microbial origin. Futamura Y, Sawa R, Umezawa Y, Igarashi M, Nakamura H, Hasegawa K, Yamasaki M, Tashiro E, Takahashi Y, Akamatsu Y, et al. J Am Chem Soc 2008 130 1822 1823 10.1021/ja710124p 18205364
-
(2008)
J Am Chem Soc
, vol.130
, pp. 1822-1823
-
-
Futamura, Y.1
Sawa, R.2
Umezawa, Y.3
Igarashi, M.4
Nakamura, H.5
Hasegawa, K.6
Yamasaki, M.7
Tashiro, E.8
Takahashi, Y.9
Akamatsu, Y.10
-
16
-
-
84857184337
-
Proteins Associated with the Exon Junction Complex Also Control the Alternative Splicing of Apoptotic Regulators
-
10.1128/MCB.06130-11 22203037
-
Proteins Associated with the Exon Junction Complex Also Control the Alternative Splicing of Apoptotic Regulators. Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, et al. Mol Cell Biol 2012 32 954 967 10.1128/MCB.06130-11 22203037
-
(2012)
Mol Cell Biol
, vol.32
, pp. 954-967
-
-
Michelle, L.1
Cloutier, A.2
Toutant, J.3
Shkreta, L.4
Thibault, P.5
Durand, M.6
Garneau, D.7
Gendron, D.8
Lapointe, E.9
Couture, S.10
-
17
-
-
48549102186
-
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress
-
10.1158/0008-5472.CAN-08-0035 18593938
-
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress. Lovat PE, Corazzari M, Armstrong JL, Martin S, Pagliarini V, Hill D, Brown AM, Piacentini M, Birch-Machin MA, Redfern CP, Cancer Res 2008 68 5363 5369 10.1158/0008-5472.CAN-08-0035 18593938
-
(2008)
Cancer Res
, vol.68
, pp. 5363-5369
-
-
Lovat, P.E.1
Corazzari, M.2
Armstrong, J.L.3
Martin, S.4
Pagliarini, V.5
Hill, D.6
Brown, A.M.7
Piacentini, M.8
Birch-Machin, M.A.9
Redfern, C.P.10
-
18
-
-
36749002683
-
Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins
-
10.2174/092986707782360079 18045130
-
Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins. Didelot C, Lanneau D, Brunet M, Joly AL, De Thonel A, Chiosis G, Garrido C, Curr Med Chem 2007 14 2839 2847 10.2174/092986707782360079 18045130
-
(2007)
Curr Med Chem
, vol.14
, pp. 2839-2847
-
-
Didelot, C.1
Lanneau, D.2
Brunet, M.3
Joly, A.L.4
De Thonel, A.5
Chiosis, G.6
Garrido, C.7
-
19
-
-
67650860453
-
Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms
-
10.1073/pnas.0905930106 19564615
-
Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms. Lu J, Kovach JS, Johnson F, Chiang J, Hodes R, Lonser R, Zhuang Z, Proc Natl Acad Sci U S A 2009 106 11697 11702 10.1073/pnas.0905930106 19564615
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 11697-11702
-
-
Lu, J.1
Kovach, J.S.2
Johnson, F.3
Chiang, J.4
Hodes, R.5
Lonser, R.6
Zhuang, Z.7
-
20
-
-
33644876210
-
DrugBank: A comprehensive resource for in silico drug discovery and exploration
-
Database issue 10.1093/nar/gkj067 16381955
-
DrugBank: a comprehensive resource for in silico drug discovery and exploration. Wishart DS, Knox C, Guo AC, Shrivastava S, Hassanali M, Stothard P, Chang Z, Woolsey J, Nucleic Acids Res 2006 34 668 D672 Database issue 10.1093/nar/gkj067 16381955
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
Shrivastava, S.4
Hassanali, M.5
Stothard, P.6
Chang, Z.7
Woolsey, J.8
-
21
-
-
0030887632
-
The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
-
10.1016/S0092-8674(00)80187-7 9094719
-
The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101. Stephens LR, Eguinoa A, Erdjument-Bromage H, Lui M, Cooke F, Coadwell J, Smrcka AS, Thelen M, Cadwallader K, Tempst P, et al. Cell 1997 89 105 114 10.1016/S0092-8674(00)80187-7 9094719
-
(1997)
Cell
, vol.89
, pp. 105-114
-
-
Stephens, L.R.1
Eguinoa, A.2
Erdjument-Bromage, H.3
Lui, M.4
Cooke, F.5
Coadwell, J.6
Smrcka, A.S.7
Thelen, M.8
Cadwallader, K.9
Tempst, P.10
-
22
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
16847462
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Engelman JA, Luo J, Cantley LC, Nat Rev Genet 2006 7 606 619 16847462
-
(2006)
Nat Rev Genet
, vol.7
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
23
-
-
33646370512
-
BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance
-
16291747
-
BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance. Hickey FB, Cotter TG, J Biol Chem 2006 281 2441 2450 16291747
-
(2006)
J Biol Chem
, vol.281
, pp. 2441-2450
-
-
Hickey, F.B.1
Cotter, T.G.2
-
24
-
-
77958032063
-
Key role of phosphoinositide 3-kinase class IB in pancreatic cancer
-
10.1158/1078-0432.CCR-10-1210 20876794
-
Key role of phosphoinositide 3-kinase class IB in pancreatic cancer. Edling CE, Selvaggi F, Buus R, Maffucci T, Di Sebastiano P, Friess H, Innocenti P, Kocher HM, Falasca M, Clin Cancer Res 2010 16 4928 4937 10.1158/1078-0432. CCR-10-1210 20876794
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4928-4937
-
-
Edling, C.E.1
Selvaggi, F.2
Buus, R.3
Maffucci, T.4
Di Sebastiano, P.5
Friess, H.6
Innocenti, P.7
Kocher, H.M.8
Falasca, M.9
-
25
-
-
4344685333
-
The PARP superfamily
-
10.1002/bies.20085 15273990
-
The PARP superfamily. Ame JC, Spenlehauer C, de Murcia G, Bioessays 2004 26 882 893 10.1002/bies.20085 15273990
-
(2004)
Bioessays
, vol.26
, pp. 882-893
-
-
Ame, J.C.1
Spenlehauer, C.2
De Murcia, G.3
-
26
-
-
24344454692
-
Poly(ADP-ribosyl)ation by PARP-1: PAR-laying NAD+into a nuclear signal
-
10.1101/gad.1331805 16140981
-
Poly(ADP-ribosyl)ation by PARP-1: PAR-laying NAD+into a nuclear signal. Kim MY, Zhang T, Kraus WL, Genes Dev 2005 19 1951 1967 10.1101/gad.1331805 16140981
-
(2005)
Genes Dev
, vol.19
, pp. 1951-1967
-
-
Kim, M.Y.1
Zhang, T.2
Kraus, W.L.3
-
27
-
-
0035796025
-
Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death
-
10.1016/S0027-5107(01)00111-7 11376691
-
Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Herceg Z, Wang ZQ, Mutat Res 2001 477 97 110 10.1016/S0027-5107(01)00111-7 11376691
-
(2001)
Mutat Res
, vol.477
, pp. 97-110
-
-
Herceg, Z.1
Wang, Z.Q.2
-
28
-
-
0030984490
-
PARP is important for genomic stability but dispensable in apoptosis
-
10.1101/gad.11.18.2347 9308963
-
PARP is important for genomic stability but dispensable in apoptosis. Wang ZQ, Stingl L, Morrison C, Jantsch M, Los M, Schulze-Osthoff K, Wagner EF, Genes Dev 1997 11 2347 2358 10.1101/gad.11.18.2347 9308963
-
(1997)
Genes Dev
, vol.11
, pp. 2347-2358
-
-
Wang, Z.Q.1
Stingl, L.2
Morrison, C.3
Jantsch, M.4
Los, M.5
Schulze-Osthoff, K.6
Wagner, E.F.7
-
29
-
-
39749166975
-
DNA repair pathways as targets for cancer therapy
-
10.1038/nrc2342 18256616
-
DNA repair pathways as targets for cancer therapy. Helleday T, Petermann E, Lundin C, Hodgson B, Sharma RA, Nat Rev Cancer 2008 8 193 204 10.1038/nrc2342 18256616
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 193-204
-
-
Helleday, T.1
Petermann, E.2
Lundin, C.3
Hodgson, B.4
Sharma, R.A.5
-
30
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
10.1038/nature03445 15829967
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, et al. Nature 2005 434 917 921 10.1038/nature03445 15829967
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
Santarosa, M.7
Dillon, K.J.8
Hickson, I.9
Knights, C.10
-
31
-
-
34249784216
-
Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models
-
10.1158/1078-0432.CCR-06-2872 17505006
-
Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models. Albert JM, Cao C, Kim KW, Willey CD, Geng L, Xiao D, Wang H, Sandler A, Johnson DH, Colevas AD, et al. Clin Cancer Res 2007 13 3033 3042 10.1158/1078-0432.CCR-06-2872 17505006
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3033-3042
-
-
Albert, J.M.1
Cao, C.2
Kim, K.W.3
Willey, C.D.4
Geng, L.5
Xiao, D.6
Wang, H.7
Sandler, A.8
Johnson, D.H.9
Colevas, A.D.10
-
32
-
-
0141619287
-
Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1
-
14522929
-
Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1. Veuger SJ, Curtin NJ, Richardson CJ, Smith GC, Durkacz BW, Cancer Res 2003 63 6008 6015 14522929
-
(2003)
Cancer Res
, vol.63
, pp. 6008-6015
-
-
Veuger, S.J.1
Curtin, N.J.2
Richardson, C.J.3
Smith, G.C.4
Durkacz, B.W.5
-
33
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
10.1126/science.1072221 12114629
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL, Science 2002 297 259 263 10.1126/science.1072221 12114629
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
34
-
-
2442621492
-
Role of AIF in caspase-dependent and caspase-independent cell death
-
10.1038/sj.onc.1207517 15077142
-
Role of AIF in caspase-dependent and caspase-independent cell death. Cregan SP, Dawson VL, Slack RS, Oncogene 2004 23 2785 2796 10.1038/sj.onc. 1207517 15077142
-
(2004)
Oncogene
, vol.23
, pp. 2785-2796
-
-
Cregan, S.P.1
Dawson, V.L.2
Slack, R.S.3
-
35
-
-
2142694340
-
Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling
-
10.1016/j.tips.2004.03.005 15120492
-
Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Hong SJ, Dawson TM, Dawson VL, Trends Pharmacol Sci 2004 25 259 264 10.1016/j.tips.2004.03.005 15120492
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 259-264
-
-
Hong, S.J.1
Dawson, T.M.2
Dawson, V.L.3
-
36
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
10.1038/nrc2222 17882277
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Menendez JA, Lupu R, Nat Rev Cancer 2007 7 763 777 10.1038/nrc2222 17882277
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
37
-
-
23044482013
-
RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells
-
10.1158/0008-5472.CAN-05-0571 16061653
-
RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. Brusselmans K, De Schrijver E, Verhoeven G, Swinnen JV, Cancer Res 2005 65 6719 6725 10.1158/0008-5472.CAN-05-0571 16061653
-
(2005)
Cancer Res
, vol.65
, pp. 6719-6725
-
-
Brusselmans, K.1
De Schrijver, E.2
Verhoeven, G.3
Swinnen, J.V.4
-
38
-
-
33744808464
-
Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival
-
10.1158/0008-5472.CAN-05-1489 16707454
-
Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival. Chajes V, Cambot M, Moreau K, Lenoir GM, Joulin V, Cancer Res 2006 66 5287 5294 10.1158/0008-5472.CAN-05-1489 16707454
-
(2006)
Cancer Res
, vol.66
, pp. 5287-5294
-
-
Chajes, V.1
Cambot, M.2
Moreau, K.3
Lenoir, G.M.4
Joulin, V.5
-
39
-
-
67349227746
-
Acetyl-CoA carboxylase-alpha inhibitor TOFA induces human cancer cell apoptosis
-
10.1016/j.bbrc.2009.05.045 19450551
-
Acetyl-CoA carboxylase-alpha inhibitor TOFA induces human cancer cell apoptosis. Wang C, Xu C, Sun M, Luo D, Liao DF, Cao D, Biochem Biophys Res Commun 2009 385 302 306 10.1016/j.bbrc.2009.05.045 19450551
-
(2009)
Biochem Biophys Res Commun
, vol.385
, pp. 302-306
-
-
Wang, C.1
Xu, C.2
Sun, M.3
Luo, D.4
Liao, D.F.5
Cao, D.6
-
40
-
-
34548580317
-
Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells
-
10.1158/0008-5472.CAN-07-0389 17804731
-
Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells. Beckers A, Organe S, Timmermans L, Scheys K, Peeters A, Brusselmans K, Verhoeven G, Swinnen JV, Cancer Res 2007 67 8180 8187 10.1158/0008-5472.CAN-07-0389 17804731
-
(2007)
Cancer Res
, vol.67
, pp. 8180-8187
-
-
Beckers, A.1
Organe, S.2
Timmermans, L.3
Scheys, K.4
Peeters, A.5
Brusselmans, K.6
Verhoeven, G.7
Swinnen, J.V.8
-
41
-
-
0030706079
-
Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma
-
9815604
-
Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma. Milgraum LZ, Witters LA, Pasternack GR, Kuhajda FP, Clin Cancer Res 1997 3 2115 2120 9815604
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2115-2120
-
-
Milgraum, L.Z.1
Witters, L.A.2
Pasternack, G.R.3
Kuhajda, F.P.4
-
42
-
-
0033814153
-
Selective activation of the fatty acid synthesis pathway in human prostate cancer
-
10.1002/1097-0215(20001015)88:2<176: AID-IJC5>3.0.CO;2-3 11004665
-
Selective activation of the fatty acid synthesis pathway in human prostate cancer. Swinnen JV, Vanderhoydonc F, Elgamal AA, Eelen M, Vercaeren I, Joniau S, Van Poppel H, Baert L, Goossens K, Heyns W, et al. Int J Cancer 2000 88 176 179 10.1002/1097-0215(20001015)88:2<176::AID-IJC5>3.0.CO;2-3 11004665
-
(2000)
Int J Cancer
, vol.88
, pp. 176-179
-
-
Swinnen, J.V.1
Vanderhoydonc, F.2
Elgamal, A.A.3
Eelen, M.4
Vercaeren, I.5
Joniau, S.6
Van Poppel, H.7
Baert, L.8
Goossens, K.9
Heyns, W.10
-
44
-
-
34548095157
-
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
-
10.1038/nchembio.2007.18 17643111
-
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Kaida D, Motoyoshi H, Tashiro E, Nojima T, Hagiwara M, Ishigami K, Watanabe H, Kitahara T, Yoshida T, Nakajima H, et al. Nat Chem Biol 2007 3 576 583 10.1038/nchembio.2007.18 17643111
-
(2007)
Nat Chem Biol
, vol.3
, pp. 576-583
-
-
Kaida, D.1
Motoyoshi, H.2
Tashiro, E.3
Nojima, T.4
Hagiwara, M.5
Ishigami, K.6
Watanabe, H.7
Kitahara, T.8
Yoshida, T.9
Nakajima, H.10
-
45
-
-
0037106283
-
A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics
-
10.1021/ac020018n 12349976
-
A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics. Natsume T, Yamauchi Y, Nakayama H, Shinkawa T, Yanagida M, Takahashi N, Isobe T, Anal Chem 2002 74 4725 4733 10.1021/ac020018n 12349976
-
(2002)
Anal Chem
, vol.74
, pp. 4725-4733
-
-
Natsume, T.1
Yamauchi, Y.2
Nakayama, H.3
Shinkawa, T.4
Yanagida, M.5
Takahashi, N.6
Isobe, T.7
-
47
-
-
0037099395
-
-
10.1002/1521-3773(20020715)41:14<2596: AID-ANIE2596>3.0.CO;2-4
-
Rostovtsev VV, Green LG, Fokin VV, Sharpless KB, Angew Chem Int Ed 2002 41 2596 2599 10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2- 4
-
(2002)
Angew Chem Int Ed
, vol.41
, pp. 2596-2599
-
-
Rostovtsev, V.V.1
Green, L.G.2
Fokin, V.V.3
Sharpless, K.B.4
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