Inhibition of -secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia

Molecular Neurodegeneration

Volumn 7, Issue 1, 2012, Pages

  Tamayev, Robert ^a   Dadamio, Luciano ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; ENZYME INHIBITOR; SECRETASE;

AMINO TERMINAL SEQUENCE; AMNESIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DEMENTIA; ENZYME ACTIVITY; ENZYME INHIBITION; GENETICS; HIPPOCAMPUS; MOUSE; NONHUMAN; SYNAPSE; ANIMAL; CATARACT; CEREBELLAR ATAXIA; DISEASE MODEL; ENZYMOLOGY; GENE TARGETING; HEARING IMPAIRMENT; MEMORY DISORDER; METABOLISM; WESTERN BLOTTING;

MUS;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; CATARACT; CEREBELLAR ATAXIA; DEAFNESS; DEMENTIA; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; GENE KNOCK-IN TECHNIQUES; MEMORY DISORDERS; MICE;

EID: 84862161020     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-7-19     Document Type: Article

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