Scalable synthesis of enantiomerically pure bicyclo[2.2.2]octadiene ligands

Journal of Organic Chemistry

Volumn 77, Issue 10, 2012, Pages 4765-4773

  Abele, Stefan ^a   Inauen, Roman ^a   Spielvogel, Dirk ^b   Moessner, Christian ^b  

^a ACTELION PHARMACEUTICALS LTD   (Switzerland)

^b SOLVIAS AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BICYCLIC PRODUCTS; OCTADIENE; ONE POT; ORGANOCATALYTIC; PHENYLACETALDEHYDE; SCALABLE SYNTHESIS;

ADDITION REACTIONS; CONDENSATION REACTIONS; ENANTIOMERS; KETONES; OLEFINS;

LIGANDS;

2 CYCLOHEXENONE; 6 HYDROXY 5 PHENYLBICYCLO[2.2.2]OCTAN 2 ONE; ACETALDEHYDE; BICYCLO COMPOUND; BICYCLO[2.2.2]OCTADIENE; BICYCLO[2.2.2]OCTANE DERIVATIVE; CRYSTALLIN; LIGAND; PHENYLACETALDEHYDE; PHENYLBICYCLO[2.2.2]OCT 5 EN 2 ONE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; ASYMMETRIC CATALYSIS; BIOTRANSFORMATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; CONTROLLED STUDY; ENANTIOMER; ENANTIOSELECTIVITY; MICHAEL ADDITION; ONE POT SYNTHESIS; ORGANOCATALYSIS; STEREOCHEMISTRY;

ACETALDEHYDE; BICYCLO COMPOUNDS; CATALYSIS; CYCLOHEXANONES; LIGANDS; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 84862063769     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo3005638     Document Type: Article

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