Design and scale-up of a practical enantioselective route to 5-Phenylbicyclo[2.2.2]oct-5-en-2-one

Organic Process Research and Development

Volumn 16, Issue 1, 2012, Pages 129-140

  Abele, Stefan ^a   Inauen, Roman ^a   Funel, Jacques Alexis ^a   Weller, Thomas ^a  

^a ACTELION PHARMACEUTICALS LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL PURITY; CHIRAL PURITY; COLORLESS CRYSTALS; DIASTEREOMERS; ENANTIOMERIC RATIO; ENANTIOSELECTIVE; IN-SITU; INTRAMOLECULAR ALDOL REACTIONS; REACTION CONDITIONS; SCALE-UP; SECONDARY ALCOHOLS; TARGET COMPOUND;

ALDEHYDES; CHROMATOGRAPHY; CONDENSATION REACTIONS; DISTILLATION; ENANTIOSELECTIVITY; KETONES; ORGANIC COMPOUNDS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

REACTION INTERMEDIATES;

EID: 84856148644     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200305y     Document Type: Article

References (71)

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