-
1
-
-
0037319276
-
Drug delivery to the retina: challenges and opportunities
-
10.1517/14712598.3.1.45, 12718730
-
Duvvuri S, Majumdar S, Mitra AK. Drug delivery to the retina: challenges and opportunities. Expert Opin Biol Ther 2003, 3:45-56. 10.1517/14712598.3.1.45, 12718730.
-
(2003)
Expert Opin Biol Ther
, vol.3
, pp. 45-56
-
-
Duvvuri, S.1
Majumdar, S.2
Mitra, A.K.3
-
2
-
-
39149121847
-
Current and future ophthalmic drug delivery systems. A shift to the posterior segment
-
Del Amo EM, Urtti A. Current and future ophthalmic drug delivery systems. A shift to the posterior segment. Drug DiscovToday 2008, 13:135-143.
-
(2008)
Drug DiscovToday
, vol.13
, pp. 135-143
-
-
Del Amo, E.M.1
Urtti, A.2
-
3
-
-
67349220667
-
Ophthalmic drug delivery: development and regulatory considerations
-
Novack GD. Ophthalmic drug delivery: development and regulatory considerations. ClinPharmacolTher 2009, 85:539-543.
-
(2009)
ClinPharmacolTher
, vol.85
, pp. 539-543
-
-
Novack, G.D.1
-
4
-
-
33751187547
-
Challenges and obstacles of ocular pharmacokinetics and drug delivery
-
10.1016/j.addr.2006.07.027, 17097758
-
Urtti A. Challenges and obstacles of ocular pharmacokinetics and drug delivery. Adv Drug Deliv Rev 2006, 58:1131-1135. 10.1016/j.addr.2006.07.027, 17097758.
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 1131-1135
-
-
Urtti, A.1
-
5
-
-
79955022978
-
Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications
-
10.1167/iovs.10-5392, 3061492, 20980702
-
Edelhauser HF, Rowe-Rendleman CL, Robinson MR, Dawson DG, Chader GJ, Grossniklaus HE, Rittenhouse KD, Wilson CG, Weber DA, Kuppermann BD, et al. Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications. Invest Ophthalmol Vis Sci 2010, 51:5403-5420. 10.1167/iovs.10-5392, 3061492, 20980702.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 5403-5420
-
-
Edelhauser, H.F.1
Rowe-Rendleman, C.L.2
Robinson, M.R.3
Dawson, D.G.4
Chader, G.J.5
Grossniklaus, H.E.6
Rittenhouse, K.D.7
Wilson, C.G.8
Weber, D.A.9
Kuppermann, B.D.10
-
6
-
-
63049131601
-
Thermoresponsive hydrogels as a new ocular drug delivery platform to the posterior segment of the eye
-
Kang Derwent JJ, Mieler WF. Thermoresponsive hydrogels as a new ocular drug delivery platform to the posterior segment of the eye. TransAmOphthalmolSoc 2008, 106:206-213.
-
(2008)
TransAmOphthalmolSoc
, vol.106
, pp. 206-213
-
-
Kang Derwent, J.J.1
Mieler, W.F.2
-
7
-
-
62849109726
-
Novel drug delivery systems for retinal diseases
-
Lee SS, Robinson MR. Novel drug delivery systems for retinal diseases. A review. Ophthalmic Res 2009, 41:124-135.
-
(2009)
A review. Ophthalmic Res
, vol.41
, pp. 124-135
-
-
Lee, S.S.1
Robinson, M.R.2
-
8
-
-
77149141784
-
Biodegradable intraocular therapies for retinal disorders: progress to date
-
10.2165/11530970-000000000-00000, 20104938
-
Kuno N, Fujii S. Biodegradable intraocular therapies for retinal disorders: progress to date. Drugs Aging 2010, 27:117-134. 10.2165/11530970-000000000-00000, 20104938.
-
(2010)
Drugs Aging
, vol.27
, pp. 117-134
-
-
Kuno, N.1
Fujii, S.2
-
9
-
-
79953329178
-
Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic macular edema
-
e622, 10.1016/j.ophtha.2010.12.028, 21459216
-
Campochiaro PA, Brown DM, Pearson A, Ciulla T, Boyer D, Holz FG, Tolentino M, Gupta A, Duarte L, Madreperla S, et al. Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic macular edema. Ophthalmology 2011, 118:626-635. e622, 10.1016/j.ophtha.2010.12.028, 21459216.
-
(2011)
Ophthalmology
, vol.118
, pp. 626-635
-
-
Campochiaro, P.A.1
Brown, D.M.2
Pearson, A.3
Ciulla, T.4
Boyer, D.5
Holz, F.G.6
Tolentino, M.7
Gupta, A.8
Duarte, L.9
Madreperla, S.10
-
10
-
-
79958211809
-
The dexamethasone drug delivery system: indications and evidence
-
10.1007/s12325-011-0019-z, 21494891
-
London NJ, Chiang A, Haller JA. The dexamethasone drug delivery system: indications and evidence. Adv Ther 2011, 28:351-366. 10.1007/s12325-011-0019-z, 21494891.
-
(2011)
Adv Ther
, vol.28
, pp. 351-366
-
-
London, N.J.1
Chiang, A.2
Haller, J.A.3
-
11
-
-
77953173751
-
Pe'er J, Domb AJ: New techniques for drug delivery to the posterior eye segment
-
10.1007/s11095-009-0042-9, 20155388
-
Eljarrat-Binstock E. Pe'er J, Domb AJ: New techniques for drug delivery to the posterior eye segment. Pharm Res 2010, 27:530-543. 10.1007/s11095-009-0042-9, 20155388.
-
(2010)
Pharm Res
, vol.27
, pp. 530-543
-
-
Eljarrat-Binstock, E.1
-
13
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
10.1038/35888, 9486653
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans. Nature 1998, 391:806-811. 10.1038/35888, 9486653.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
14
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
10.1038/35078107, 11373684
-
Elbashir S, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001, 411:494-498. 10.1038/35078107, 11373684.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
15
-
-
34447559636
-
Interfering with disease: a progress report on siRNA-based therapeutics
-
de Fougerolles A, Vornlocher HP, Maraganore J, Lieberman J. Interfering with disease: a progress report on siRNA-based therapeutics. Nature Rev Drug Discov 2007, 6:443-453.
-
(2007)
Nature Rev Drug Discov
, vol.6
, pp. 443-453
-
-
de Fougerolles, A.1
Vornlocher, H.P.2
Maraganore, J.3
Lieberman, J.4
-
16
-
-
70350233314
-
Basal Cancer Cell Survival Involves JNK2 Suppression of a Novel JNK1/c-Jun/Bcl-3 Apoptotic Network
-
10.1371/journal.pone.0007305, 2752166, 19806201
-
Ahmed SU, Milner J. Basal Cancer Cell Survival Involves JNK2 Suppression of a Novel JNK1/c-Jun/Bcl-3 Apoptotic Network. PLoS One 2009, 4:e7305. 10.1371/journal.pone.0007305, 2752166, 19806201.
-
(2009)
PLoS One
, vol.4
-
-
Ahmed, S.U.1
Milner, J.2
-
17
-
-
52049090811
-
Chemically modified siRNA: tools and applications
-
10.1016/j.drudis.2008.05.007, 18614389
-
Watts JK, Deleavey GF, Damha MJ. Chemically modified siRNA: tools and applications. Drug Discovery Today 2008, 13:842-855. 10.1016/j.drudis.2008.05.007, 18614389.
-
(2008)
Drug Discovery Today
, vol.13
, pp. 842-855
-
-
Watts, J.K.1
Deleavey, G.F.2
Damha, M.J.3
-
18
-
-
59349116903
-
Knocking down barriers: advances in siRNA delivery
-
10.1038/nrd2742, 19180106
-
Whitehead K, Langer R, Anderson D. Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov 2009, 8:129-138. 10.1038/nrd2742, 19180106.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 129-138
-
-
Whitehead, K.1
Langer, R.2
Anderson, D.3
-
20
-
-
40449083756
-
Targeted delivery of small interfering RNA: approaching effective cancer therapies
-
10.1158/0008-5472.CAN-07-5810, 18316585
-
Pirollo K, Chang E. Targeted delivery of small interfering RNA: approaching effective cancer therapies. Cancer Res 2008, 68:1247-1250. 10.1158/0008-5472.CAN-07-5810, 18316585.
-
(2008)
Cancer Res
, vol.68
, pp. 1247-1250
-
-
Pirollo, K.1
Chang, E.2
-
21
-
-
84857134544
-
Gene therapy in the Cornea: 2005-present
-
10.1016/j.preteyeres.2011.09.001, 21967960
-
Mohan R, Tovey J, Sharma A, Tandon A. Gene therapy in the Cornea: 2005-present. Prog Retin Eye Res 2012, 31:43-64. 10.1016/j.preteyeres.2011.09.001, 21967960.
-
(2012)
Prog Retin Eye Res
, vol.31
, pp. 43-64
-
-
Mohan, R.1
Tovey, J.2
Sharma, A.3
Tandon, A.4
-
22
-
-
77956650867
-
Viral vector-mediated RNA interference
-
10.1016/j.coph.2010.06.007, 20620113
-
Couto L, High K. Viral vector-mediated RNA interference. Curr Opin Pharmacol 2010, 10:534-542. 10.1016/j.coph.2010.06.007, 20620113.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 534-542
-
-
Couto, L.1
High, K.2
-
23
-
-
80052887982
-
Subretinal gene delivery using helper-dependent adenoviral vectors
-
10.1186/2045-3701-1-15, 3125205, 21711866
-
Wu L, Lam S, Cao H, Guan R, Hu J. Subretinal gene delivery using helper-dependent adenoviral vectors. Cell Biosci 2011, 1:15. 10.1186/2045-3701-1-15, 3125205, 21711866.
-
(2011)
Cell Biosci
, vol.1
, pp. 15
-
-
Wu, L.1
Lam, S.2
Cao, H.3
Guan, R.4
Hu, J.5
-
24
-
-
77349095284
-
Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab
-
Höbel S, Koburger I, John M, Czubayko F, Hadwiger P, Vornlocher H, Aigner A. Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab. J Gene Med 2010, 12:287-300.
-
(2010)
J Gene Med
, vol.12
, pp. 287-300
-
-
Höbel, S.1
Koburger, I.2
John, M.3
Czubayko, F.4
Hadwiger, P.5
Vornlocher, H.6
Aigner, A.7
-
25
-
-
75749121523
-
Suppression of ICAM-1 in retinal and choroidal endothelial cells by plasmid small-interfering RNAs in vivo
-
10.1167/iovs.09-3457, 19578010
-
Hirano Y, Sakurai E, Matsubara A, Ogura Y. Suppression of ICAM-1 in retinal and choroidal endothelial cells by plasmid small-interfering RNAs in vivo. Invest Ophthalmol Vis Sci 2010, 51:508-515. 10.1167/iovs.09-3457, 19578010.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 508-515
-
-
Hirano, Y.1
Sakurai, E.2
Matsubara, A.3
Ogura, Y.4
-
26
-
-
77954620685
-
Nanoparticles for retinal gene therapy
-
10.1016/j.preteyeres.2010.04.004, 2907107, 20452457
-
Conley S, Naash M. Nanoparticles for retinal gene therapy. Prog Retin Eye Res 2010, 29:376-397. 10.1016/j.preteyeres.2010.04.004, 2907107, 20452457.
-
(2010)
Prog Retin Eye Res
, vol.29
, pp. 376-397
-
-
Conley, S.1
Naash, M.2
-
27
-
-
80052876653
-
Nano-vectors for the Ocular Delivery of Nucleic Acid-based Therapeutics
-
10.4103/0250-474X.84575, 3178967, 21969738
-
Khar R, Jain G, Warsi M, Mallick N, Akhter S, Pathan S, Ahmad F. Nano-vectors for the Ocular Delivery of Nucleic Acid-based Therapeutics. Indian J Pharm Sci 2010, 72:675-688. 10.4103/0250-474X.84575, 3178967, 21969738.
-
(2010)
Indian J Pharm Sci
, vol.72
, pp. 675-688
-
-
Khar, R.1
Jain, G.2
Warsi, M.3
Mallick, N.4
Akhter, S.5
Pathan, S.6
Ahmad, F.7
-
28
-
-
61649106233
-
Gene delivery to the retina: focus on non-viral approaches
-
10.1016/j.drudis.2008.09.012, 18973824
-
Naik R, Mukhopadhyay A, Ganguli M. Gene delivery to the retina: focus on non-viral approaches. Drug Discov Today 2009, 14:306-315. 10.1016/j.drudis.2008.09.012, 18973824.
-
(2009)
Drug Discov Today
, vol.14
, pp. 306-315
-
-
Naik, R.1
Mukhopadhyay, A.2
Ganguli, M.3
-
29
-
-
0029160083
-
Lezoualc'h F, Zanta M, Mergny M, Scherman D, Demeneix B, Behr J: A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine
-
10.1073/pnas.92.16.7297, 41326, 7638184
-
Boussif O. Lezoualc'h F, Zanta M, Mergny M, Scherman D, Demeneix B, Behr J: A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. PNAS 1995, 92:7297-7301. 10.1073/pnas.92.16.7297, 41326, 7638184.
-
(1995)
PNAS
, vol.92
, pp. 7297-7301
-
-
Boussif, O.1
-
30
-
-
33746871883
-
Biophysical and Structural Characterization of Polyethylenimine-Mediated siRNA Delivery in Vitro
-
10.1007/s11095-006-9009-2, 16845585
-
Grayson A, Doody A, Putnam D. Biophysical and Structural Characterization of Polyethylenimine-Mediated siRNA Delivery in Vitro. Pharm Res 2006, 23:1868-1876. 10.1007/s11095-006-9009-2, 16845585.
-
(2006)
Pharm Res
, vol.23
, pp. 1868-1876
-
-
Grayson, A.1
Doody, A.2
Putnam, D.3
-
31
-
-
9644275599
-
Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis
-
10.1016/S0002-9440(10)63267-1, 1618707, 15579459
-
Kim B, Tang Q, Biswas P, Xu J, Schiffelers R, Xie F, Ansari A, Scaria P, Woodle M, Lu P, Rouse B. Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis. Am J Pathol 2004, 165:2177-2185. 10.1016/S0002-9440(10)63267-1, 1618707, 15579459.
-
(2004)
Am J Pathol
, vol.165
, pp. 2177-2185
-
-
Kim, B.1
Tang, Q.2
Biswas, P.3
Xu, J.4
Schiffelers, R.5
Xie, F.6
Ansari, A.7
Scaria, P.8
Woodle, M.9
Lu, P.10
Rouse, B.11
-
32
-
-
79952317711
-
Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung
-
10.1016/j.ejpb.2010.11.007, 21093588
-
Günther M, Lipka J, Malek A, Gutsch D, Kreyling W, Aigner A. Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung. Eur J Pharm Biopharm 2011, 77:438-449. 10.1016/j.ejpb.2010.11.007, 21093588.
-
(2011)
Eur J Pharm Biopharm
, vol.77
, pp. 438-449
-
-
Günther, M.1
Lipka, J.2
Malek, A.3
Gutsch, D.4
Kreyling, W.5
Aigner, A.6
-
33
-
-
58149354432
-
Cationic nano-copolymers mediated IKKbeta targeting siRNA inhibit the proliferation of human Tenon's capsule fibroblasts in vitro
-
2613073, 19137061
-
Duan Y, Guan X, Ge J, Quan D, Zhuo Y, Ye H, Shao T. Cationic nano-copolymers mediated IKKbeta targeting siRNA inhibit the proliferation of human Tenon's capsule fibroblasts in vitro. Mol Vis 2008, 14:2616-2628. 2613073, 19137061.
-
(2008)
Mol Vis
, vol.14
, pp. 2616-2628
-
-
Duan, Y.1
Guan, X.2
Ge, J.3
Quan, D.4
Zhuo, Y.5
Ye, H.6
Shao, T.7
-
34
-
-
78650798166
-
Cationic nano-copolymers mediated IKKβ targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery
-
2997334, 21139997
-
Ye H, Qian Y, Lin M, Duan Y, Sun X, Zhuo Y, Ge J. Cationic nano-copolymers mediated IKKβ targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery. Mol Vis 2010, 16:2502-2510. 2997334, 21139997.
-
(2010)
Mol Vis
, vol.16
, pp. 2502-2510
-
-
Ye, H.1
Qian, Y.2
Lin, M.3
Duan, Y.4
Sun, X.5
Zhuo, Y.6
Ge, J.7
-
35
-
-
0021025270
-
Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene
-
10.1073/pnas.80.23.7128, 390006, 6580630
-
Soriano P, Dijkstra J, Legrand A, Spanjer H, Londos-Gagliardi D, Roerdink F, Scherphof G, Nicolau C. Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene. PNAS 1983, 80:7128-7131. 10.1073/pnas.80.23.7128, 390006, 6580630.
-
(1983)
PNAS
, vol.80
, pp. 7128-7131
-
-
Soriano, P.1
Dijkstra, J.2
Legrand, A.3
Spanjer, H.4
Londos-Gagliardi, D.5
Roerdink, F.6
Scherphof, G.7
Nicolau, C.8
-
36
-
-
80052386408
-
A Lipid Nanoparticle System Improves siRNA Efficacy in RPE Cells and a Laser-Induced Murine CNV Model
-
10.1167/iovs.10-5891, 21519028
-
Liu H, Liu Y, Ma Z, Wang J, Zhang Q. A Lipid Nanoparticle System Improves siRNA Efficacy in RPE Cells and a Laser-Induced Murine CNV Model. Invest Ophthalmol Vis Sci 2011, 52:4789-4794. 10.1167/iovs.10-5891, 21519028.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 4789-4794
-
-
Liu, H.1
Liu, Y.2
Ma, Z.3
Wang, J.4
Zhang, Q.5
-
37
-
-
77951498926
-
DC-Chol/DOPE cationic liposomes: a comparative study of the influence factors on plasmid pDNA and siRNA gene delivery
-
10.1016/j.ijpharm.2010.01.035, 20116418
-
Zhang Y, Li H, Sun J, Gao J, Liu W, Li B, Guo Y, Chen J. DC-Chol/DOPE cationic liposomes: a comparative study of the influence factors on plasmid pDNA and siRNA gene delivery. Int J Pharm 2010, 390:198-207. 10.1016/j.ijpharm.2010.01.035, 20116418.
-
(2010)
Int J Pharm
, vol.390
, pp. 198-207
-
-
Zhang, Y.1
Li, H.2
Sun, J.3
Gao, J.4
Liu, W.5
Li, B.6
Guo, Y.7
Chen, J.8
-
38
-
-
14844300910
-
Albumin-protamine-oligonucleotide nanoparticles as a new antisense delivery system. Part 1: Physicochemical characterization
-
10.1016/j.ejpb.2004.04.001, 15760722
-
Lochmann D, Weyermann J, Georgens C, Prassl R, Zimmer A. Albumin-protamine-oligonucleotide nanoparticles as a new antisense delivery system. Part 1: Physicochemical characterization. Eur J Pharm Biopharm 2005, 59:419-429. 10.1016/j.ejpb.2004.04.001, 15760722.
-
(2005)
Eur J Pharm Biopharm
, vol.59
, pp. 419-429
-
-
Lochmann, D.1
Weyermann, J.2
Georgens, C.3
Prassl, R.4
Zimmer, A.5
-
39
-
-
37549064689
-
Cell-penetrating peptide for enhanced delivery of nucleic acids and drugs to ocular tissues including retina and cornea
-
10.1038/sj.mt.6300324, 17923842
-
Johnson L, Cashman S, Kumar-Singh R. Cell-penetrating peptide for enhanced delivery of nucleic acids and drugs to ocular tissues including retina and cornea. Mol Ther 2008, 16:107-114. 10.1038/sj.mt.6300324, 17923842.
-
(2008)
Mol Ther
, vol.16
, pp. 107-114
-
-
Johnson, L.1
Cashman, S.2
Kumar-Singh, R.3
-
40
-
-
59849091278
-
Peptide-Mediated Cellular Delivery of Oligonucleotide-Based Therapeutics In Vitro: Quantitative Evaluation of Overall Efficacy Employing Easy to Handle Reporter Systems
-
10.2174/138161208786898806, 2778081, 19075740
-
Laufer S, Restle T. Peptide-Mediated Cellular Delivery of Oligonucleotide-Based Therapeutics In Vitro: Quantitative Evaluation of Overall Efficacy Employing Easy to Handle Reporter Systems. Curr Pharm Des 2008, 14:3637-3655. 10.2174/138161208786898806, 2778081, 19075740.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 3637-3655
-
-
Laufer, S.1
Restle, T.2
-
41
-
-
79952939225
-
Recent advances of siRNA delivery by nanoparticles
-
10.1517/17425247.2011.559223, 21413903
-
Yuan X, Naguib S, Wu Z. Recent advances of siRNA delivery by nanoparticles. Expert Opin Drug Deliv 2011, 8:521-536. 10.1517/17425247.2011.559223, 21413903.
-
(2011)
Expert Opin Drug Deliv
, vol.8
, pp. 521-536
-
-
Yuan, X.1
Naguib, S.2
Wu, Z.3
-
42
-
-
4544332801
-
Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide
-
10.1016/j.exer.2004.06.023, 15381036
-
Marano R, Wimmer N, Kearns P, Thomas B, Toth I, Brankov M, Rakoczy P. Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Exp Eye Res 2004, 79:525-535. 10.1016/j.exer.2004.06.023, 15381036.
-
(2004)
Exp Eye Res
, vol.79
, pp. 525-535
-
-
Marano, R.1
Wimmer, N.2
Kearns, P.3
Thomas, B.4
Toth, I.5
Brankov, M.6
Rakoczy, P.7
-
43
-
-
27544499791
-
Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity
-
10.1038/sj.gt.3302579, 16034458
-
Marano R, Toth I, Wimmer N, Brankov M, Rakoczy P. Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Ther 2005, 12:1544-1550. 10.1038/sj.gt.3302579, 16034458.
-
(2005)
Gene Ther
, vol.12
, pp. 1544-1550
-
-
Marano, R.1
Toth, I.2
Wimmer, N.3
Brankov, M.4
Rakoczy, P.5
-
44
-
-
70349551739
-
Functional delivery of siRNA in mice using dendriworms
-
10.1021/nn900201e, 2828182, 19673534
-
Agrawal A, Min D, Singh N, Zhu H, Bhatia S. Functional delivery of siRNA in mice using dendriworms. ACS Nano 2009, 3:2495-2504. 10.1021/nn900201e, 2828182, 19673534.
-
(2009)
ACS Nano
, vol.3
, pp. 2495-2504
-
-
Agrawal, A.1
Min, D.2
Singh, N.3
Zhu, H.4
Bhatia, S.5
-
45
-
-
77950948806
-
Tat-BMPs-PAMAM conjugates enhance therapeutic effect of small interference RNA on U251 glioma cells in vitro and in vivo
-
10.1089/hum.2009.087, 19899955
-
Han L, Zhang A, Wang H, Pu P, Jiang X, Kang C, Chang J. Tat-BMPs-PAMAM conjugates enhance therapeutic effect of small interference RNA on U251 glioma cells in vitro and in vivo. Hum Gene Ther 2010, 21:417-426. 10.1089/hum.2009.087, 19899955.
-
(2010)
Hum Gene Ther
, vol.21
, pp. 417-426
-
-
Han, L.1
Zhang, A.2
Wang, H.3
Pu, P.4
Jiang, X.5
Kang, C.6
Chang, J.7
-
48
-
-
77953909544
-
RNAi-based treatment for neovascular age-related macular degeneration by Sirna-027
-
10.1016/j.ajo.2010.02.006, 20609706
-
Kaiser P, Symons R, Shah S, Quinlan E, Nguyen Q. RNAi-based treatment for neovascular age-related macular degeneration by Sirna-027. Am J Ophthalmol 2010, 150:33-39. 10.1016/j.ajo.2010.02.006, 20609706.
-
(2010)
Am J Ophthalmol
, vol.150
, pp. 33-39
-
-
Kaiser, P.1
Symons, R.2
Shah, S.3
Quinlan, E.4
Nguyen, Q.5
-
55
-
-
77952043572
-
RNAi-based therapeutics-current status, challenges and prospects
-
10.1002/emmm.200900023, 3378126, 20049714
-
Tiemann K, Rossi J. RNAi-based therapeutics-current status, challenges and prospects. EMBO Mol Med 2009, 1:142-151. 10.1002/emmm.200900023, 3378126, 20049714.
-
(2009)
EMBO Mol Med
, vol.1
, pp. 142-151
-
-
Tiemann, K.1
Rossi, J.2
-
56
-
-
20044396377
-
Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication
-
10.1002/hep.20702, 15880588
-
Morrissey D, Blanchard K, Shaw L, Jensen K, Lockridge J, Dickinson B, McSwiggen J, Vargeese C, Bowman K, Shaffer C, et al. Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication. Hepatology 2005, 41:1349-1356. 10.1002/hep.20702, 15880588.
-
(2005)
Hepatology
, vol.41
, pp. 1349-1356
-
-
Morrissey, D.1
Blanchard, K.2
Shaw, L.3
Jensen, K.4
Lockridge, J.5
Dickinson, B.6
McSwiggen, J.7
Vargeese, C.8
Bowman, K.9
Shaffer, C.10
-
58
-
-
22344454846
-
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
-
10.1038/nbt1081, 15778705
-
Judge AD, Sood V, Shaw JR, Fang D, McClintock K, MacLachlan I. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol 2005, 23:457-462. 10.1038/nbt1081, 15778705.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 457-462
-
-
Judge, A.D.1
Sood, V.2
Shaw, J.R.3
Fang, D.4
McClintock, K.5
MacLachlan, I.6
-
59
-
-
21244497878
-
Positional effect of chemical modifications on short interference RNA activity in mammalian cells
-
10.1021/jm050044o, 15974578
-
Prakash T, Allerson C, Dande P, Vickers T, Sioufi N, Jarres R, Baker B, Swayze E, Griffey R, Bhat B. Positional effect of chemical modifications on short interference RNA activity in mammalian cells. J Med Chem 2005, 48:4247-4253. 10.1021/jm050044o, 15974578.
-
(2005)
J Med Chem
, vol.48
, pp. 4247-4253
-
-
Prakash, T.1
Allerson, C.2
Dande, P.3
Vickers, T.4
Sioufi, N.5
Jarres, R.6
Baker, B.7
Swayze, E.8
Griffey, R.9
Bhat, B.10
-
60
-
-
0038606999
-
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
-
10.1093/nar/gkg393, 156727, 12771196
-
Czauderna F, Fechtner M, Dames S, Aygün H, Klippel A, Pronk G, Giese K, Kaufmann J. Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res 2003, 31:2705-2716. 10.1093/nar/gkg393, 156727, 12771196.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2705-2716
-
-
Czauderna, F.1
Fechtner, M.2
Dames, S.3
Aygün, H.4
Klippel, A.5
Pronk, G.6
Giese, K.7
Kaufmann, J.8
-
61
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
Morrissey D, Lockridge J, Shaw L, Blanchard K, Jensen K, Breen W, Hartsough K, Machemer L, Radka S, Jadhav V, et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nature Biotechnol 2005, 23:1002-1007.
-
(2005)
Nature Biotechnol
, vol.23
, pp. 1002-1007
-
-
Morrissey, D.1
Lockridge, J.2
Shaw, L.3
Blanchard, K.4
Jensen, K.5
Breen, W.6
Hartsough, K.7
Machemer, L.8
Radka, S.9
Jadhav, V.10
-
62
-
-
78449299462
-
Staying on message: design principles for controlling nonspecific responses to siRNA
-
10.1111/j.1742-4658.2010.07905.x, 21078117
-
Samuel-Abraham S, Leonard J. Staying on message: design principles for controlling nonspecific responses to siRNA. FEBS J 2010, 277:4828-4836. 10.1111/j.1742-4658.2010.07905.x, 21078117.
-
(2010)
FEBS J
, vol.277
, pp. 4828-4836
-
-
Samuel-Abraham, S.1
Leonard, J.2
-
63
-
-
33645763485
-
Cleavage of the siRNA passenger strand during RISC assembly in human cells
-
10.1038/sj.embor.7400637, 1456892, 16439995
-
Leuschner P, Ameres S, Kueng S, Martinez J. Cleavage of the siRNA passenger strand during RISC assembly in human cells. EMBO Rep 2006, 7:314-320. 10.1038/sj.embor.7400637, 1456892, 16439995.
-
(2006)
EMBO Rep
, vol.7
, pp. 314-320
-
-
Leuschner, P.1
Ameres, S.2
Kueng, S.3
Martinez, J.4
-
64
-
-
11344257391
-
RNA interference using boranophosphate siRNAs: structure-activity relationships
-
10.1093/nar/gkh936, 534620, 15545637
-
Hall AH, Wan J, Shaughnessy EE, Ramsay Shaw B, Alexander KA. RNA interference using boranophosphate siRNAs: structure-activity relationships. Nucleic Acids Res 2004, 32:5991-6000. 10.1093/nar/gkh936, 534620, 15545637.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 5991-6000
-
-
Hall, A.H.1
Wan, J.2
Shaughnessy, E.E.3
Ramsay Shaw, B.4
Alexander, K.A.5
-
65
-
-
33644620908
-
Chemical modification of siRNAs to improve serum stability without loss of efficacy
-
10.1016/j.bbrc.2006.02.049, 16598842
-
Choung S, Kim Y, Kim S, Park HO, Choi YC. Chemical modification of siRNAs to improve serum stability without loss of efficacy. Biochem Biophys Res Commun 2006, 342:919-927. 10.1016/j.bbrc.2006.02.049, 16598842.
-
(2006)
Biochem Biophys Res Commun
, vol.342
, pp. 919-927
-
-
Choung, S.1
Kim, Y.2
Kim, S.3
Park, H.O.4
Choi, Y.C.5
-
66
-
-
78449309070
-
Efficient and targeted delivery of siRNA in vivo
-
10.1111/j.1742-4658.2010.07904.x, 21078116
-
Shim M, Kwon Y. Efficient and targeted delivery of siRNA in vivo. FEBS J 2010, 277:4814-4827. 10.1111/j.1742-4658.2010.07904.x, 21078116.
-
(2010)
FEBS J
, vol.277
, pp. 4814-4827
-
-
Shim, M.1
Kwon, Y.2
-
67
-
-
28544444484
-
Phosphorothioate-stimulated uptake of short interfering RNA by human cells
-
10.1038/sj.embor.7400535, 1369202, 16170302
-
Overhoff M, Sczakiel G. Phosphorothioate-stimulated uptake of short interfering RNA by human cells. EMBO Rep 2005, 6:1176-1181. 10.1038/sj.embor.7400535, 1369202, 16170302.
-
(2005)
EMBO Rep
, vol.6
, pp. 1176-1181
-
-
Overhoff, M.1
Sczakiel, G.2
-
68
-
-
57349134691
-
Chemical modification of siRNAs for in vivo use
-
10.1089/oli.2008.0164, 19025401
-
Behlke M. Chemical modification of siRNAs for in vivo use. Oligonucleotides 2008, 18:305-319. 10.1089/oli.2008.0164, 19025401.
-
(2008)
Oligonucleotides
, vol.18
, pp. 305-319
-
-
Behlke, M.1
-
69
-
-
33745614074
-
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing
-
10.1261/rna.30706, 1484422, 16682562
-
Jackson A, Burchard J, Leake D, Reynolds A, Schelter J, Guo J, Linsley P. Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA 2006, 12:1197-1205. 10.1261/rna.30706, 1484422, 16682562.
-
(2006)
RNA
, vol.12
, pp. 1197-1205
-
-
Jackson, A.1
Burchard, J.2
Leake, D.3
Reynolds, A.4
Schelter, J.5
Guo, J.6
Linsley, P.7
-
70
-
-
0018801485
-
Structural requirements of double-stranded RNA for the activation of 2',5'-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells
-
Minks M, West D, Benvin S, Baglioni C. Structural requirements of double-stranded RNA for the activation of 2',5'-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells. J Biol Chem 1979, 254:10180-10183.
-
(1979)
J Biol Chem
, vol.254
, pp. 10180-10183
-
-
Minks, M.1
West, D.2
Benvin, S.3
Baglioni, C.4
-
71
-
-
27944459341
-
Activation of the mammalian immune system by siRNAs
-
10.1038/nbt1161, 16273073
-
Marques JT, Williams BRG. Activation of the mammalian immune system by siRNAs. Nat Biotechnol 2005, 23:1399-1405. 10.1038/nbt1161, 16273073.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1399-1405
-
-
Marques, J.T.1
Williams, B.R.G.2
-
72
-
-
41649115210
-
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
-
10.1038/nature06765, 2642938, 18368052
-
Kleinman ME, Yamada K, Takeda A, Chandrasekaran V, Nozaki M, Baffi JZ, Albuquerque RJC, Yamasaki S, Itaya M, Pan Y, et al. Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. Nature 2008, 452:591-597. 10.1038/nature06765, 2642938, 18368052.
-
(2008)
Nature
, vol.452
, pp. 591-597
-
-
Kleinman, M.E.1
Yamada, K.2
Takeda, A.3
Chandrasekaran, V.4
Nozaki, M.5
Baffi, J.Z.6
Albuquerque, R.J.C.7
Yamasaki, S.8
Itaya, M.9
Pan, Y.10
-
73
-
-
39449097277
-
Overcoming the innate immune response to small interfering RNA
-
10.1089/hum.2007.179, 18230025
-
Judge A, MacLachlan I. Overcoming the innate immune response to small interfering RNA. Human Gene Therapy 2008, 19:111-124. 10.1089/hum.2007.179, 18230025.
-
(2008)
Human Gene Therapy
, vol.19
, pp. 111-124
-
-
Judge, A.1
MacLachlan, I.2
-
74
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
Morrissey DV. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nature Biotechnol 2005, 23:1002-1007.
-
(2005)
Nature Biotechnol
, vol.23
, pp. 1002-1007
-
-
Morrissey, D.V.1
-
75
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
10.1038/nbt831, 12754523
-
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol 2003, 21:635-637. 10.1038/nbt831, 12754523.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
76
-
-
78449296513
-
Designing highly active siRNAs for therapeutic applications
-
10.1111/j.1742-4658.2010.07903.x, 3052974, 21078115
-
Walton S, Wu M, Gredell J, Chan C. Designing highly active siRNAs for therapeutic applications. FEBS J 2010, 277:4806-4813. 10.1111/j.1742-4658.2010.07903.x, 3052974, 21078115.
-
(2010)
FEBS J
, vol.277
, pp. 4806-4813
-
-
Walton, S.1
Wu, M.2
Gredell, J.3
Chan, C.4
-
77
-
-
0037124051
-
Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis
-
10.1074/jbc.M111257200, 11875062
-
Zuhorn IS, Kalicharan R, Hoekstra D. Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis. J Biol Chem 2002, 277:18021-18028. 10.1074/jbc.M111257200, 11875062.
-
(2002)
J Biol Chem
, vol.277
, pp. 18021-18028
-
-
Zuhorn, I.S.1
Kalicharan, R.2
Hoekstra, D.3
-
78
-
-
50849144942
-
Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery
-
10.1002/bip.20989, 18381624
-
Torchilin V. Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery. Biopolymers 2008, 90:604-610. 10.1002/bip.20989, 18381624.
-
(2008)
Biopolymers
, vol.90
, pp. 604-610
-
-
Torchilin, V.1
-
79
-
-
77955175216
-
Strategies in the design of nanoparticles for therapeutic applications
-
10.1038/nrd2591, 20616808
-
Petros R, DeSimone J. Strategies in the design of nanoparticles for therapeutic applications. Nat Rev Drug Discov 2010, 9:615-627. 10.1038/nrd2591, 20616808.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 615-627
-
-
Petros, R.1
DeSimone, J.2
-
80
-
-
1642575957
-
Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis
-
10.1042/BJ20031253, 1223843, 14505488
-
Rejman J, Oberle V, Zuhorn IS, Hoekstra D. Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis. Biochem J 2004, 377:159-169. 10.1042/BJ20031253, 1223843, 14505488.
-
(2004)
Biochem J
, vol.377
, pp. 159-169
-
-
Rejman, J.1
Oberle, V.2
Zuhorn, I.S.3
Hoekstra, D.4
-
81
-
-
0346634895
-
In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis
-
10.1016/S0142-9612(02)00445-3, 12527253
-
Fisher D, Ahlemeyer Y, Krieglstein B, Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials 2003, 24:1121-1131. 10.1016/S0142-9612(02)00445-3, 12527253.
-
(2003)
Biomaterials
, vol.24
, pp. 1121-1131
-
-
Fisher, D.1
Ahlemeyer, Y.2
Krieglstein, B.3
Kissel, T.4
-
82
-
-
58149277700
-
Biodegradable Quantum Dot Nanocomposites Enable Live Cell Labeling and Imaging of Cytoplasmic Targets
-
10.1021/nl802311t, 18816147
-
Kim BYS, Jiang W, Oreopoulos J, Yip CM, Rutka JT, Chan WCW. Biodegradable Quantum Dot Nanocomposites Enable Live Cell Labeling and Imaging of Cytoplasmic Targets. Nano Letters 2008, 8:3887-3892. 10.1021/nl802311t, 18816147.
-
(2008)
Nano Letters
, vol.8
, pp. 3887-3892
-
-
Kim, B.Y.S.1
Jiang, W.2
Oreopoulos, J.3
Yip, C.M.4
Rutka, J.T.5
Chan, W.C.W.6
-
83
-
-
74049133619
-
Subcellular targeting strategies for drug design and delivery
-
10.1038/nrd2897, 20043027
-
Rajendran L, Knölker H, Simons K. Subcellular targeting strategies for drug design and delivery. Nat Rev Drug Discov 2010, 9:29-42. 10.1038/nrd2897, 20043027.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 29-42
-
-
Rajendran, L.1
Knölker, H.2
Simons, K.3
-
84
-
-
0035937124
-
Arginine-rich peptides
-
Futaki S, Suzuki T, Ohashi W, Yagami T, Tanaka S, Ueda K, Sugiura Y. Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J Biol Chem 2001, 276:5836-5840.
-
(2001)
An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J Biol Chem
, vol.276
, pp. 5836-5840
-
-
Futaki, S.1
Suzuki, T.2
Ohashi, W.3
Yagami, T.4
Tanaka, S.5
Ueda, K.6
Sugiura, Y.7
-
85
-
-
36749079823
-
Imaging and Tracking of Tat Peptide-Conjugated Quantum Dots in Living Cells: New Insights into Nanoparticle Uptake, Intracellular Transport, and Vesicle Shedding
-
10.1021/ja074936k, 17983227
-
Ruan G, Agrawal A, Marcus AI, Nie S. Imaging and Tracking of Tat Peptide-Conjugated Quantum Dots in Living Cells: New Insights into Nanoparticle Uptake, Intracellular Transport, and Vesicle Shedding. J Am Chem Soc 2007, 129:14759-14766. 10.1021/ja074936k, 17983227.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 14759-14766
-
-
Ruan, G.1
Agrawal, A.2
Marcus, A.I.3
Nie, S.4
-
86
-
-
0028239908
-
The third helix of the Antennapedia homeodomain translocates through biological membranes
-
Derossi D, Joliot A, Chassaing G, Prochiantz A. The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem 1994, 269:10444-10450.
-
(1994)
J Biol Chem
, vol.269
, pp. 10444-10450
-
-
Derossi, D.1
Joliot, A.2
Chassaing, G.3
Prochiantz, A.4
-
87
-
-
33947426789
-
Cell-penetrating quantum dots based on multivalent and endosome-disrupting surface coatings
-
10.1021/ja068158s, 17319667
-
Duan H, Nie S. Cell-penetrating quantum dots based on multivalent and endosome-disrupting surface coatings. J Am Chem Soc 2007, 129:3333-3338. 10.1021/ja068158s, 17319667.
-
(2007)
J Am Chem Soc
, vol.129
, pp. 3333-3338
-
-
Duan, H.1
Nie, S.2
-
88
-
-
0037069319
-
Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells
-
10.1073/pnas.192581499, 137472, 12403826
-
Thomas M, Klibanov A. Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. PNAS 2002, 99:14640-14645. 10.1073/pnas.192581499, 137472, 12403826.
-
(2002)
PNAS
, vol.99
, pp. 14640-14645
-
-
Thomas, M.1
Klibanov, A.2
-
89
-
-
67649114761
-
Transfection Efficiency of 25-kDa PEICholesterol Conjugates with Different Levels of Modification
-
10.1163/156856209X444448, 19454171
-
Gusachenko Simonova O, Kravchuk Y, Konevets D, Silnikov V, Vlassov VV, Zenkova MA. Transfection Efficiency of 25-kDa PEICholesterol Conjugates with Different Levels of Modification. J Biomater Sci Polym Ed 2009, 20:1091-1110. 10.1163/156856209X444448, 19454171.
-
(2009)
J Biomater Sci Polym Ed
, vol.20
, pp. 1091-1110
-
-
Gusachenko Simonova, O.1
Kravchuk, Y.2
Konevets, D.3
Silnikov, V.4
Vlassov, V.V.5
Zenkova, M.A.6
-
90
-
-
34247504151
-
Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA
-
10.1021/bi062138l, 17391006
-
Bouxsein N, McAllister C, Ewert K, Samuel C, Safinya C. Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA. Biochemistry 2007, 46:4785-4792. 10.1021/bi062138l, 17391006.
-
(2007)
Biochemistry
, vol.46
, pp. 4785-4792
-
-
Bouxsein, N.1
McAllister, C.2
Ewert, K.3
Samuel, C.4
Safinya, C.5
-
91
-
-
78649527137
-
Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix
-
10.1021/ja1059763, 2991473, 21028803
-
Leal C, Bouxsein N, Ewert K, Safinya C. Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix. J Am Chem Soc 2010, 132:16841-16847. 10.1021/ja1059763, 2991473, 21028803.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 16841-16847
-
-
Leal, C.1
Bouxsein, N.2
Ewert, K.3
Safinya, C.4
-
92
-
-
79959273085
-
Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing
-
10.1021/la200679x, 3119580, 21612245
-
Leal C, Ewert K, Shirazi R, Bouxsein N, Safinya C. Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing. Langmuir 2011, 27:7691-7697. 10.1021/la200679x, 3119580, 21612245.
-
(2011)
Langmuir
, vol.27
, pp. 7691-7697
-
-
Leal, C.1
Ewert, K.2
Shirazi, R.3
Bouxsein, N.4
Safinya, C.5
-
93
-
-
79959726915
-
Enhanced delivery of monomethoxypoly(ethylene glycol)-poly(lactic-co-glycolic acid)-poly l-lysine nanoparticles loading platelet-derived growth factor BB small interfering RNA by ultrasound and/or microbubbles to rat retinal pigment epithelium cells
-
10.1002/jgm.1574, 21674734
-
Du J, Shi Q, Sun Y, Liu P, Zhu M, Du L, Duan Y. Enhanced delivery of monomethoxypoly(ethylene glycol)-poly(lactic-co-glycolic acid)-poly l-lysine nanoparticles loading platelet-derived growth factor BB small interfering RNA by ultrasound and/or microbubbles to rat retinal pigment epithelium cells. J Gene Med 2011, 13:312-323. 10.1002/jgm.1574, 21674734.
-
(2011)
J Gene Med
, vol.13
, pp. 312-323
-
-
Du, J.1
Shi, Q.2
Sun, Y.3
Liu, P.4
Zhu, M.5
Du, L.6
Duan, Y.7
-
94
-
-
77957194820
-
Non-viral siRNA delivery into the mouse retina in vivo
-
10.1186/1471-2415-10-25, 2959040, 20920307
-
Turchinovich A, Zoidl G, Dermietzel R. Non-viral siRNA delivery into the mouse retina in vivo. BMC Ophthalmol 2010, 10:25. 10.1186/1471-2415-10-25, 2959040, 20920307.
-
(2010)
BMC Ophthalmol
, vol.10
, pp. 25
-
-
Turchinovich, A.1
Zoidl, G.2
Dermietzel, R.3
-
95
-
-
65749117793
-
Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
-
10.1016/j.addr.2009.03.009, 19376175
-
Aggarwal P, Hall J, McLeland C, Dobrovolskaia A, McNeil S. Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy. Adv Drug Deliv Rev 2009, 61:428-437. 10.1016/j.addr.2009.03.009, 19376175.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 428-437
-
-
Aggarwal, P.1
Hall, J.2
McLeland, C.3
Dobrovolskaia, A.4
McNeil, S.5
-
96
-
-
23444444512
-
Biodegradable long-circulating polymeric nanospheres
-
10.1126/science.8128245, 8128245
-
Gref R, Minamitake Y, Peracchia M, Trubetskoy V, Torchilin V, Langer R. Biodegradable long-circulating polymeric nanospheres. Science 1994, 263:1600-1603. 10.1126/science.8128245, 8128245.
-
(1994)
Science
, vol.263
, pp. 1600-1603
-
-
Gref, R.1
Minamitake, Y.2
Peracchia, M.3
Trubetskoy, V.4
Torchilin, V.5
Langer, R.6
-
97
-
-
79952291790
-
Multistage nanoparticle delivery system for deep penetration into tumor tissue
-
10.1073/pnas.1018382108, 3038705, 21245339
-
Wong C, Stylianopoulos T, Cui J, Martin J, Fukumura D. Multistage nanoparticle delivery system for deep penetration into tumor tissue. PNAS 2011, 108:2426-2431. 10.1073/pnas.1018382108, 3038705, 21245339.
-
(2011)
PNAS
, vol.108
, pp. 2426-2431
-
-
Wong, C.1
Stylianopoulos, T.2
Cui, J.3
Martin, J.4
Fukumura, D.5
-
98
-
-
50149110878
-
The effect of particle design on cellular internalization pathways
-
10.1073/pnas.0801763105, 2575324, 18697944
-
Gratton S, Ropp P, Pohlhaus P, Luft J, Madden V, Napier M, DeSimone J. The effect of particle design on cellular internalization pathways. PNAS 2008, 105:11613-11618. 10.1073/pnas.0801763105, 2575324, 18697944.
-
(2008)
PNAS
, vol.105
, pp. 11613-11618
-
-
Gratton, S.1
Ropp, P.2
Pohlhaus, P.3
Luft, J.4
Madden, V.5
Napier, M.6
DeSimone, J.7
-
99
-
-
40149106154
-
Albumin-conjugated PEG liposome enhances tumor distribution of liposomal doxorubicin in rats
-
10.1016/j.ijpharm.2007.11.008, 18082345
-
Yokoe J, Sakuragi S, Yamamoto K, Teragaki T, Ogawara K, Higaki K, Katayama N, Kai T, Sato M, Kimura T. Albumin-conjugated PEG liposome enhances tumor distribution of liposomal doxorubicin in rats. Int J Pharm 2008, 353:28-34. 10.1016/j.ijpharm.2007.11.008, 18082345.
-
(2008)
Int J Pharm
, vol.353
, pp. 28-34
-
-
Yokoe, J.1
Sakuragi, S.2
Yamamoto, K.3
Teragaki, T.4
Ogawara, K.5
Higaki, K.6
Katayama, N.7
Kai, T.8
Sato, M.9
Kimura, T.10
-
100
-
-
33845593187
-
Effect of coupling of albumin onto surface of PEG liposome on its in vivo disposition
-
10.1016/j.ijpharm.2006.08.026, 17000067
-
Furumoto K, Yokoe J, Ogawara K, Amano S, Takaguchi M, Higaki K, Kai T, Kimura T. Effect of coupling of albumin onto surface of PEG liposome on its in vivo disposition. Int J Pharm 2007, 329:110-116. 10.1016/j.ijpharm.2006.08.026, 17000067.
-
(2007)
Int J Pharm
, vol.329
, pp. 110-116
-
-
Furumoto, K.1
Yokoe, J.2
Ogawara, K.3
Amano, S.4
Takaguchi, M.5
Higaki, K.6
Kai, T.7
Kimura, T.8
-
101
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
10.1038/nature08956, 2855406, 20305636
-
Davis M, Zuckerman J, Choi C, Seligson D, Ribas A. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010, 464:1067-1070. 10.1038/nature08956, 2855406, 20305636.
-
(2010)
Nature
, vol.464
, pp. 1067-1070
-
-
Davis, M.1
Zuckerman, J.2
Choi, C.3
Seligson, D.4
Ribas, A.5
-
102
-
-
80052406557
-
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
-
10.1038/nature10358, 21886163
-
Breitbach C, Burke J, Jonker D, Stephenson J, Haas A, Kirn D. Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature 2011, 477:99-102. 10.1038/nature10358, 21886163.
-
(2011)
Nature
, vol.477
, pp. 99-102
-
-
Breitbach, C.1
Burke, J.2
Jonker, D.3
Stephenson, J.4
Haas, A.5
Kirn, D.6
-
103
-
-
65249102723
-
Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles
-
10.1021/bm801199z, 2769516, 19239276
-
Hu Y, Atukorale P, Lu J, Moon J, Um S, Cho E, Wang Y, Chen J, Irvine D. Cytosolic delivery mediated via electrostatic surface binding of protein, virus, or siRNA cargos to pH-responsive core-shell gel particles. Biomacromolecules 2009, 10:756-765. 10.1021/bm801199z, 2769516, 19239276.
-
(2009)
Biomacromolecules
, vol.10
, pp. 756-765
-
-
Hu, Y.1
Atukorale, P.2
Lu, J.3
Moon, J.4
Um, S.5
Cho, E.6
Wang, Y.7
Chen, J.8
Irvine, D.9
|