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Volumn 9, Issue , 2012, Pages

Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle

Author keywords

Fuel switching; Glucose; Lipids; Mitochondria; Skeletal muscle

Indexed keywords

ESTROGEN RELATED RECEPTOR ALPHA; GLUCOSE; INSULIN; LIPID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PYRUVATE DEHYDROGENASE KINASE 4;

EID: 84861942697     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-9-53     Document Type: Article
Times cited : (43)

References (66)
  • 1
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • 10.2337/diabetes.51.10.2944 12351431
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Kelley DE, He J, Menshikova EV, Ritov VB, Diabetes 2002 51 2944 2950 10.2337/diabetes.51.10.2944 12351431
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 3
    • 33845514376 scopus 로고    scopus 로고
    • Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia
    • DOI 10.2337/db05-1230
    • Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia. Asmann YW, Stump CS, Short KR, Coenen-Schimke JM, Guo Z, Bigelow ML, Nair KS, Diabetes 2006 55 3309 3319 10.2337/db05-1230 17130474 (Pubitemid 44923587)
    • (2006) Diabetes , vol.55 , Issue.12 , pp. 3309-3319
    • Asmann, Y.W.1    Stump, C.S.2    Short, K.R.3    Coenen-Schimke, J.M.4    Guo, Z.5    Bigelow, M.L.6    Nair, K.S.7
  • 6
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • DOI 10.1056/NEJMoa031314
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI, N Engl J Med 2004 350 664 671 10.1056/NEJMoa031314 14960743 (Pubitemid 38364625)
    • (2004) New England Journal of Medicine , vol.350 , Issue.7 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 7
    • 12144275294 scopus 로고    scopus 로고
    • Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
    • DOI 10.2337/diabetes.54.1.8
    • Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE, Diabetes 2005 54 8 14 10.2337/diabetes.54.1.8 15616005 (Pubitemid 40105089)
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 8-14
    • Ritov, V.B.1    Menshikova, E.V.2    He, J.3    Ferrell, R.E.4    Goodpaster, B.H.5    Kelley, D.E.6
  • 8
    • 21344444333 scopus 로고    scopus 로고
    • A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
    • DOI 10.2337/diabetes.54.7.1926
    • A high- fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Sparks LM, Xie H, Koza RA, Mynatt R, Hulver MW, Bray GA, Smith SR, Diabetes 2005 54 1926 1933 10.2337/diabetes.54.7.1926 15983191 (Pubitemid 40911253)
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 1926-1933
    • Sparks, L.M.1    Xie, H.2    Koza, R.A.3    Mynatt, R.4    Hulver, M.W.5    Bray, G.A.6    Smith, S.R.7
  • 9
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • DOI 10.1126/science.1104343
    • Mitochondrial dysfunction and type 2 diabetes. Lowell BB, Shulman GI, Science 2005 307 384 387 10.1126/science.1104343 15662004 (Pubitemid 40139974)
    • (2005) Science , vol.307 , Issue.5708 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 10
    • 33845542745 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
    • 17130651
    • Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Morino K, Petersen KF, Shulman GI, Diabetes 2006 55 Suppl 2 9 S15 17130651
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 2
    • Morino, K.1    Petersen, K.F.2    Shulman, G.I.3
  • 13
    • 34547588219 scopus 로고    scopus 로고
    • Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
    • DOI 10.2337/db07-0093
    • Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents. Turner N, Bruce CR, Beale SM, Hoehn KL, So T, Rolph MS, Cooney GJ, Diabetes 2007 56 2085 2092 10.2337/db07-0093 17519422 (Pubitemid 47195821)
    • (2007) Diabetes , vol.56 , Issue.8 , pp. 2085-2092
    • Turner, N.1    Bruce, C.R.2    Beale, S.M.3    Hoehn, K.L.4    So, T.5    Rolph, M.S.6    Cooney, G.J.7
  • 14
    • 25844432311 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ co-activator 1α-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency
    • DOI 10.1074/jbc.M507621200
    • Peroxisome proliferator-activated receptor-gamma co- activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, Muoio DM, J Biol Chem 2005 280 33588 33598 10.1074/jbc.M507621200 16079133 (Pubitemid 41397160)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.39 , pp. 33588-33598
    • Koves, T.R.1    Li, P.2    An, J.3    Akimoto, T.4    Slentz, D.5    Ilkayeva, O.6    Dohm, G.L.7    Yan, Z.8    Newgard, C.B.9    Muoio, D.M.10
  • 15
    • 79955930100 scopus 로고    scopus 로고
    • Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance
    • 10.1371/journal.pone.0019739 21589859
    • Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance. Han DH, Hancock CR, Jung SR, Higashida K, Kim SH, Holloszy JO, PLoS One 2011 6 19739 10.1371/journal.pone.0019739 21589859
    • (2011) PLoS One , vol.6 , pp. 519739
    • Han, D.H.1    Hancock, C.R.2    Jung, S.R.3    Higashida, K.4    Kim, S.H.5    Holloszy, J.O.6
  • 16
    • 63849125267 scopus 로고    scopus 로고
    • Insulin resistance and fuel homeostasis: The role of AMP-activated protein kinase
    • 10.1111/j.1748-1716.2009.01968.x
    • Insulin resistance and fuel homeostasis: the role of AMP-activated protein kinase. Hegarty BD, Turner N, Cooney GJ, Kraegen EW, Acta Physiol (Oxf) 2009 196 129 145 10.1111/j.1748-1716.2009.01968.x
    • (2009) Acta Physiol (Oxf) , vol.196 , pp. 129-145
    • Hegarty, B.D.1    Turner, N.2    Cooney, G.J.3    Kraegen, E.W.4
  • 17
    • 58149379936 scopus 로고    scopus 로고
    • Skeletal muscle "mitochondrial deficiency" does not mediate insulin resistance
    • 19056574
    • Skeletal muscle "mitochondrial deficiency" does not mediate insulin resistance. Holloszy JO, Am J Clin Nutr 2009 89 463S 466S 19056574
    • (2009) Am J Clin Nutr , vol.89
    • Holloszy, J.O.1
  • 18
    • 34547596186 scopus 로고    scopus 로고
    • Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes
    • DOI 10.2337/db07-0141
    • Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes. Toledo FG, Menshikova EV, Ritov VB, Azuma K, Radikova Z, DeLany J, Kelley DE, Diabetes 2007 56 2142 2147 10.2337/db07-0141 17536063 (Pubitemid 47195831)
    • (2007) Diabetes , vol.56 , Issue.8 , pp. 2142-2147
    • Toledo, F.G.S.1    Menshikova, E.V.2    Ritov, V.B.3    Azuma, K.4    Radikova, Z.5    DeLany, J.6    Kelley, D.E.7
  • 19
    • 22244483764 scopus 로고    scopus 로고
    • Skeletal muscle lipid and its association with insulin resistance: What is the role for exercise?
    • DOI 10.1097/00003677-200507000-00008
    • Skeletal muscle lipid and its association with insulin resistance: what is the role for exercise? Goodpaster BH, Brown NF, Exerc Sport Sci Rev 2005 33 150 154 10.1097/00003677-200507000-00008 16006823 (Pubitemid 40994568)
    • (2005) Exercise and Sport Sciences Reviews , vol.33 , Issue.3 , pp. 150-154
    • Goodpaster, B.H.1    Brown, N.F.2
  • 21
    • 53649107138 scopus 로고    scopus 로고
    • PGC-1alpha-mediated regulation of gene expression and metabolism: Implications for nutrition and exercise prescriptions
    • 10.1139/H08-074 18923559
    • PGC-1alpha-mediated regulation of gene expression and metabolism: implications for nutrition and exercise prescriptions. Benton CR, Wright DC, Bonen A, Appl Physiol Nutr Metab 2008 33 843 862 10.1139/H08-074 18923559
    • (2008) Appl Physiol Nutr Metab , vol.33 , pp. 843-862
    • Benton, C.R.1    Wright, D.C.2    Bonen, A.3
  • 25
    • 0032792498 scopus 로고    scopus 로고
    • Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes
    • DOI 10.2337/diabetes.48.8.1593
    • Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes. Wu P, Inskeep K, Bowker-Kinley MM, Popov KM, Harris RA, Diabetes 1999 48 1593 1599 10.2337/diabetes.48.8.1593 10426378 (Pubitemid 29356868)
    • (1999) Diabetes , vol.48 , Issue.8 , pp. 1593-1599
    • Wu, P.1    Inskeep, K.2    Bowker-Kinley, M.M.3    Popov, K.M.4    Harris, R.A.5
  • 26
    • 0037322888 scopus 로고    scopus 로고
    • Exercise induces transient transcriptional activation of the PGC-1α gene in human skeletal muscle
    • DOI 10.1113/jphysiol.2002.034850
    • Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. Pilegaard H, Saltin B, Neufer PD, J Physiol 2003 546 851 858 10.1113/jphysiol.2002.034850 12563009 (Pubitemid 36204518)
    • (2003) Journal of Physiology , vol.546 , Issue.3 , pp. 851-858
    • Pilegaard, H.1    Saltin, B.2    Neufer, D.P.3
  • 27
    • 21244477127 scopus 로고    scopus 로고
    • Exercise stimulates Pgc-1α transcription in skeletal muscle through activation of the p38 MAPK pathway
    • DOI 10.1074/jbc.M408862200
    • Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway. Akimoto T, Pohnert SC, Li P, Zhang M, Gumbs C, Rosenberg PB, Williams RS, Yan Z, J Biol Chem 2005 280 19587 19593 10.1074/jbc.M408862200 15767263 (Pubitemid 41379480)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.20 , pp. 19587-19593
    • Akimoto, T.1    Pohnert, S.C.2    Li, P.3    Zhang, M.4    Gumbs, C.5    Rosenberg, P.B.6    Williams, R.S.7    Yan, Z.8
  • 29
    • 0036903174 scopus 로고    scopus 로고
    • Adaptations of skeletal muscle to exercise: Rapid increase in the transcriptional coactivator PGC-1
    • DOI 10.1096/fj.02-0367com
    • Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. Baar K, WenDe AR, Jones TE, Marison M, Nolte LA, Chen M, Kelly DP, Holloszy JO, FASEB J 2002 16 1879 1886 10.1096/fj.02-0367com 12468452 (Pubitemid 35462607)
    • (2002) FASEB Journal , vol.16 , Issue.14 , pp. 1879-1886
    • Baar, K.1    WenDe, A.R.2    Jones, T.E.3    Marison, M.4    Nolte, L.A.5    Chen, M.6    Kelly, D.P.7    Holloszy, J.O.8
  • 30
    • 0036386911 scopus 로고    scopus 로고
    • Effects of low- intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle
    • 10.1016/S0006-291X(02)00881-1 12163024
    • Effects of low- intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle. Terada S, Goto M, Kato M, Kawanaka K, Shimokawa T, Tabata I, Biochem Biophys Res Commun 2002 296 350 354 10.1016/S0006-291X(02) 00881-1 12163024
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 350-354
    • Terada, S.1    Goto, M.2    Kato, M.3    Kawanaka, K.4    Shimokawa, T.5    Tabata, I.6
  • 31
    • 28544438180 scopus 로고    scopus 로고
    • PGC-1α coactivates PDK4 gene expression via the orphan nuclear receptor ERRα: A mechanism for transcriptional control of muscle glucose metabolism
    • DOI 10.1128/MCB.25.24.10684-10694.2005
    • PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism. WenDe AR, Huss JM, Schaeffer PJ, Giguere V, Kelly DP, Mol Cell Biol 2005 25 10684 10694 10.1128/MCB.25.24.10684-10694.2005 16314495 (Pubitemid 41747115)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.24 , pp. 10684-10694
    • WenDe, A.R.1    Huss, J.M.2    Schaeffer, P.J.3    Giguere, V.4    Kelly, D.P.5
  • 32
    • 71849109938 scopus 로고    scopus 로고
    • Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin
    • 10.1016/j.mce.2009.08.011 19703515
    • Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin. Connaughton S, Chowdhury F, Attia RR, Song S, Zhang Y, Elam MB, Cook GA, Park EA, Mol Cell Endocrinol 2010 315 159 167 10.1016/j.mce.2009.08.011 19703515
    • (2010) Mol Cell Endocrinol , vol.315 , pp. 159-167
    • Connaughton, S.1    Chowdhury, F.2    Attia, R.R.3    Song, S.4    Zhang, Y.5    Elam, M.B.6    Cook, G.A.7    Park, E.A.8
  • 33
    • 34249727164 scopus 로고    scopus 로고
    • Transcriptional coregulators in the control of energy homeostasis
    • DOI 10.1016/j.tcb.2007.04.001, PII S0962892407000840
    • Transcriptional coregulators in the control of energy homeostasis. Feige JN, Auwerx J, Trends Cell Biol 2007 17 292 301 10.1016/j.tcb.2007.04.001 17475497 (Pubitemid 46829846)
    • (2007) Trends in Cell Biology , vol.17 , Issue.6 , pp. 292-301
    • Feige, J.N.1    Auwerx, J.2
  • 35
    • 0032192401 scopus 로고    scopus 로고
    • Insulin downregulates pyruvate dehydrogenase kinase (PDK) mRNA: Potential mechanism contributing to increased lipid oxidation in insulin- resistant subjects
    • DOI 10.1006/mgme.1998.2748
    • Insulin downregulates pyruvate dehydrogenase kinase (PDK) mRNA: potential mechanism contributing to increased lipid oxidation in insulin-resistant subjects. Majer M, Popov KM, Harris RA, Bogardus C, Prochazka M, Mol Genet Metab 1998 65 181 186 10.1006/mgme.1998.2748 9787110 (Pubitemid 28507139)
    • (1998) Molecular Genetics and Metabolism , vol.65 , Issue.2 , pp. 181-186
    • Majer, M.1    Popov, K.M.2    Harris, R.A.3    Bogardus, C.4    Prochazka, M.5
  • 36
    • 2942724616 scopus 로고    scopus 로고
    • Transcriptional regulation of pyruvate dehydrogenase kinase 4 in skeletal muscle during and after exercise
    • DOI 10.1079/PNS2004345
    • Transcriptional regulation of pyruvate dehydrogenase kinase 4 in skeletal muscle during and after exercise. Pilegaard H, Neufer PD, Proc Nutr Soc 2004 63 221 226 10.1079/PNS2004345 15294034 (Pubitemid 38787469)
    • (2004) Proceedings of the Nutrition Society , vol.63 , Issue.2 , pp. 221-226
    • Pilegaard, H.1    Neufer, P.D.2
  • 37
    • 33646865314 scopus 로고    scopus 로고
    • Identification of ERRα as a specific partner of PGC-1α for the activation of PDK4 gene expression in muscle
    • DOI 10.1111/j.1742-4658.2006.05183.x
    • Identification of ERRalpha as a specific partner of PGC-1alpha for the activation of PDK4 gene expression in muscle. Araki M, Motojima K, FEBS J 2006 273 1669 1680 10.1111/j.1742-4658.2006.05183.x 16623704 (Pubitemid 43779821)
    • (2006) FEBS Journal , vol.273 , Issue.8 , pp. 1669-1680
    • Araki, M.1    Motojima, K.2
  • 40
    • 30344484849 scopus 로고    scopus 로고
    • Gene expression in human skeletal muscle: Alternative normalization method and effect of repeated biopsies
    • DOI 10.1007/s00421-005-0022-7
    • Gene expression in human skeletal muscle: alternative normalization method and effect of repeated biopsies. Lundby C, Nordsborg N, Kusuhara K, Kristensen KM, Neufer PD, Pilegaard H, Eur J Appl Physiol 2005 95 351 360 10.1007/s00421-005-0022-7 16151837 (Pubitemid 43055098)
    • (2005) European Journal of Applied Physiology , vol.95 , Issue.4 , pp. 351-360
    • Lundby, C.1    Nordsborg, N.2    Kusuhara, K.3    Kristensen, K.M.4    Neufer, P.D.5    Pilegaard, H.6
  • 41
    • 66349104285 scopus 로고    scopus 로고
    • Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men
    • 10.1152/japplphysiol.00087.2009 19299575
    • Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men. Hulmi JJ, Tannerstedt J, Selanne H, Kainulainen H, KoVanen V, Mero AA, J Appl Physiol 2009 106 1720 1729 10.1152/japplphysiol. 00087.2009 19299575
    • (2009) J Appl Physiol , vol.106 , pp. 1720-1729
    • Hulmi, J.J.1    Tannerstedt, J.2    Selanne, H.3    Kainulainen, H.4    KoVanen, V.5    Mero, A.A.6
  • 42
    • 84856166319 scopus 로고    scopus 로고
    • Altered REDD1, myostatin, and Akt/mTOR/FoxO/MAPK signaling in streptozotocin-induced diabetic muscle atrophy
    • 10.1152/ajpendo.00398.2011 22068602
    • Altered REDD1, myostatin, and Akt/mTOR/FoxO/MAPK signaling in streptozotocin-induced diabetic muscle atrophy. Hulmi JJ, Silvennoinen M, Lehti M, Kivela R, Kainulainen H, Am J Physiol Endocrinol Metab 2012 302 307 E315 10.1152/ajpendo.00398.2011 22068602
    • (2012) Am J Physiol Endocrinol Metab , vol.302
    • Hulmi, J.J.1    Silvennoinen, M.2    Lehti, M.3    Kivela, R.4    Kainulainen, H.5
  • 43
    • 0020645217 scopus 로고
    • Response of succinate dehydrogenase activity in fibres of rabbit tibialis anterior muscle to chronic nerve stimulation
    • Response of succinate dehydrogenase activity in fibres of rabbit tibialis anterior muscle to chronic nerve stimulation. Pette D, Tyler KR, J Physiol 1983 338 1 9 6224003 (Pubitemid 13099471)
    • (1983) Journal of Physiology , vol.338 , pp. 1-9
    • Pette, D.1    Tyler, K.R.2
  • 44
    • 0021518733 scopus 로고
    • Oxygen consumption and oxidative capacity of muscles from young obese and nonobese Zucker rats
    • 6093607
    • Oxygen consumption and oxidative capacity of muscles from young obese and nonobese Zucker rats. Wardlaw GM, Kaplan ML, Am J Physiol 1984 247 911 R917 6093607
    • (1984) Am J Physiol , vol.247
    • Wardlaw, G.M.1    Kaplan, M.L.2
  • 45
    • 42449132297 scopus 로고    scopus 로고
    • Transcriptional control of energy homeostasis through the PGC1 coactivators
    • 3-6; discusssion 6-12, 162-3
    • Transcriptional control of energy homeostasis through the PGC1 coactivators. Spiegelman BM, Novartis Found Symp 2007 286 196 203 3-6; discusssion 6-12, 162-3
    • (2007) Novartis Found Symp , vol.286 , pp. 196-203
    • Spiegelman, B.M.1
  • 46
    • 33845289819 scopus 로고    scopus 로고
    • Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases
    • DOI 10.1080/13813450600935263, PII T6152666M0301757
    • Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases. Sugden MC, Holness MJ, Arch Physiol Biochem 2006 112 139 149 10.1080/13813450600935263 17132539 (Pubitemid 44871041)
    • (2006) Archives of Physiology and Biochemistry , vol.112 , Issue.3 , pp. 139-149
    • Sugden, M.C.1    Holness, M.J.2
  • 47
    • 33846066872 scopus 로고    scopus 로고
    • High-fat/low-carbohydrate diet reduces insulin-stimulated carbohydrate oxidation but stimulates nonoxidative glucose disposal in humans: An important role for skeletal muscle pyruvate dehydrogenase kinase 4
    • DOI 10.1210/jc.2006-1592
    • High-fat/low carbohydrate diet reduces insulin- stimulated carbohydrate oxidation but stimulates nonoxidative glucose disposal in humans: An important role for skeletal muscle pyruvate dehydrogenase kinase 4. Chokkalingam K, Jewell K, Norton L, Littlewood J, Van Loon LJ, Mansell P, Macdonald IA, Tsintzas K, J Clin Endocrinol Metab 2007 92 284 292 17062764 (Pubitemid 46067545)
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , Issue.1 , pp. 284-292
    • Chokkalingam, K.1    Jewell, K.2    Norton, L.3    Littlewood, J.4    Van Loon, L.J.C.5    Mansell, P.6    Macdonald, I.A.7    Tsintzas, K.8
  • 48
    • 0034074642 scopus 로고    scopus 로고
    • Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow- twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding
    • Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high- fat feeding. Holness MJ, Kraus A, Harris RA, Sugden MC, Diabetes 2000 49 775 781 10.2337/diabetes.49.5.775 10905486 (Pubitemid 30339993)
    • (2000) Diabetes , vol.49 , Issue.5 , pp. 775-781
    • Holness, M.J.1    Kraus, A.2    Harris, R.A.3    Sugden, M.C.4
  • 49
    • 67650069923 scopus 로고    scopus 로고
    • Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation
    • 10.1152/ajpendo.90945.2008 19366875
    • Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation. Hoy AJ, Brandon AE, Turner N, Watt MJ, Bruce CR, Cooney GJ, Kraegen EW, Am J Physiol Endocrinol Metab 2009 297 67 E75 10.1152/ajpendo.90945. 2008 19366875
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Hoy, A.J.1    Brandon, A.E.2    Turner, N.3    Watt, M.J.4    Bruce, C.R.5    Cooney, G.J.6    Kraegen, E.W.7
  • 51
    • 0033538473 scopus 로고    scopus 로고
    • Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
    • DOI 10.1016/S0092-8674(00)80611-X
    • Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM, Cell 1999 98 115 124 10.1016/S0092-8674(00)80611-X 10412986 (Pubitemid 29331201)
    • (1999) Cell , vol.98 , Issue.1 , pp. 115-124
    • Wu, Z.1    Puigserver, P.2    Andersson, U.3    Zhang, C.4    Adelmant, G.5    Mootha, V.6    Troy, A.7    Cinti, S.8    Lowell, B.9    Scarpulla, R.C.10    Spiegelman, B.M.11
  • 52
    • 34447511610 scopus 로고    scopus 로고
    • Peroxisome proliferator activator receptor γ coactivator-1 expression is reduced in obesity: Potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation
    • DOI 10.1074/jbc.M611214200
    • Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME, J Biol Chem 2007 282 15439 15450 10.1074/jbc.M611214200 17416903 (Pubitemid 47093279)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.21 , pp. 15439-15450
    • Crunkhorn, S.1    Dearie, F.2    Mantzoros, C.3    Gami, H.4    Da Silva, W.S.5    Espinoza, D.6    Faucette, R.7    Barry, K.8    Bianco, A.C.9    Patti, M.E.10
  • 53
    • 76249092706 scopus 로고    scopus 로고
    • Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells
    • 10.1159/000276566 20110694
    • Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells. Rodriguez AM, Sanchez J, Tobaruela A, Priego T, Pico C, Palou A, Cell Physiol Biochem 2010 25 337 346 10.1159/000276566 20110694
    • (2010) Cell Physiol Biochem , vol.25 , pp. 337-346
    • Rodriguez, A.M.1    Sanchez, J.2    Tobaruela, A.3    Priego, T.4    Pico, C.5    Palou, A.6
  • 54
    • 0242580188 scopus 로고    scopus 로고
    • Reduced Fat Mass in Mice Lacking Orphan Nuclear Receptor Estrogen-Related Receptor α
    • DOI 10.1128/MCB.23.22.7947-7956.2003
    • Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha. Luo J, Sladek R, Carrier J, Bader JA, Richard D, Giguere V, Mol Cell Biol 2003 23 7947 7956 10.1128/MCB.23.22.7947-7956.2003 14585956 (Pubitemid 37377488)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.22 , pp. 7947-7956
    • Luo, J.1    Sladek, R.2    Carrier, J.3    Bader, J.-A.4    Richard, D.5    Giguere, V.6
  • 55
    • 0030787844 scopus 로고    scopus 로고
    • The orphan nuclear receptor estrogen-related receptor or α is a transcriptional regulator of the human medium-cha n Acyl coenzyme A dehydrogenase gene
    • The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Sladek R, Bader JA, Giguere V, Mol Cell Biol 1997 17 5400 5409 9271417 (Pubitemid 27357638)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.9 , pp. 5400-5409
    • Sladek, R.1    Bader, J.-A.2    Giguere, V.3
  • 56
    • 79953210362 scopus 로고    scopus 로고
    • Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis
    • Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis. Fernandez-Marcos PJ, Auwerx J, Giguere V, Am J Clin Nutr 2001 93
    • (2001) Am J Clin Nutr , vol.93
    • Fernandez-Marcos, P.J.1    Auwerx, J.2    Giguere, V.3
  • 58
    • 33644861790 scopus 로고    scopus 로고
    • Central orexin sensitivity, physical activity, and obesity in diet-induced obese and diet resistant rats
    • 16188908
    • Central orexin sensitivity, physical activity, and obesity in diet-induced obese and diet resistant rats. Novak CM, Kotz CM, Levine JA, Am J Physiol Endocrinol Metab 2006 290 396 E403 16188908
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Novak, C.M.1    Kotz, C.M.2    Levine, J.A.3
  • 59
    • 84856143975 scopus 로고    scopus 로고
    • The use of a running wheel to measure activity in rodents: Relationship to energy balance, general activity, and reward
    • 10.1016/j.neubiorev.2011.12.012 22230703
    • The use of a running wheel to measure activity in rodents: relationship to energy balance, general activity, and reward. Novak CM, Burghardt PR, Levine JA, Neurosci Biobehav Rev 2012 36 1001 1014 10.1016/j.neubiorev.2011.12.012 22230703
    • (2012) Neurosci Biobehav Rev , vol.36 , pp. 1001-1014
    • Novak, C.M.1    Burghardt, P.R.2    Levine, J.A.3
  • 60
    • 0030664299 scopus 로고    scopus 로고
    • Insulin resistance of muscle glucose transport in rats fed a high-fat diet: A reevaluation
    • Insulin resistance of muscle glucose transport in rats fed a high-fat diet: a reevaluation. Han DH, Hansen PA, Host HH, Holloszy JO, Diabetes 1997 46 1761 1767 10.2337/diabetes.46.11.1761 9356023 (Pubitemid 27456408)
    • (1997) Diabetes , vol.46 , Issue.11 , pp. 1761-1767
    • Han, D.-H.1    Hansen, P.A.2    Host, H.H.3    Holloszy, J.O.4
  • 61
    • 34247131735 scopus 로고    scopus 로고
    • Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer
    • DOI 10.1007/s00018-007-6380-z
    • Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer. Roche TE, Hiromasa Y, Cell Mol Life Sci 2007 64 830 849 10.1007/s00018-007-6380-z 17310282 (Pubitemid 46597752)
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.7-8 , pp. 830-849
    • Roche, T.E.1    Hiromasa, Y.2
  • 62
    • 0034282947 scopus 로고    scopus 로고
    • Starvation increases the amount of pyruvate dehydrogenase kinase in several mammalian tissues
    • 10.1006/abbi.2000.1946 11019813
    • Starvation increases the amount of pyruvate dehydrogenase kinase in several mammalian tissues. Wu P, Blair PV, Sato J, Jaskiewicz J, Popov KM, Harris RA, Arch Biochem Biophys 2000 381 1 7 10.1006/abbi.2000.1946 11019813
    • (2000) Arch Biochem Biophys , vol.381 , pp. 1-7
    • Wu, P.1    Blair, P.V.2    Sato, J.3    Jaskiewicz, J.4    Popov, K.M.5    Harris, R.A.6
  • 63
    • 67650085023 scopus 로고    scopus 로고
    • Is fat-induced muscle insulin resistance rapidly reversible?
    • 10.1152/ajpendo.00244.2009 19435855
    • Is fat-induced muscle insulin resistance rapidly reversible? Han DH, Hancock C, Jung SR, Holloszy JO, Am J Physiol Endocrinol Metab 2009 297 236 E241 10.1152/ajpendo.00244.2009 19435855
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Han, D.H.1    Hancock, C.2    Jung, S.R.3    Holloszy, J.O.4
  • 64
    • 27744556268 scopus 로고    scopus 로고
    • Lipid microdomains and insulin resistance: Is there a connection
    • 10.1126/stke.2682005pe3 22803140
    • Lipid microdomains and insulin resistance: is there a connection. Ikonen E, Vainio S, Science's STKE 2005 2005 e3 10.1126/stke.2682005pe3 22803140
    • (2005) Science's STKE , vol.2005
    • Ikonen, E.1    Vainio, S.2
  • 65
    • 0031688509 scopus 로고    scopus 로고
    • Insulin signaling and glucose transport in insulin resistant skeletal muscle. Special reference to GLUT4 transgenic and GLUT4 knockout mice
    • 9781315
    • Insulin signaling and glucose transport in insulin resistant skeletal muscle. Special reference to GLUT4 transgenic and GLUT4 knockout mice. Galuska D, Ryder J, Kawano Y, Charron MJ, Zierath JR, Adv Exp Med Biol 1998 441 73 85 9781315
    • (1998) Adv Exp Med Biol , vol.441 , pp. 73-85
    • Galuska, D.1    Ryder, J.2    Kawano, Y.3    Charron, M.J.4    Zierath, J.R.5
  • 66
    • 33750877988 scopus 로고    scopus 로고
    • Palmitate-mediated downregulation of peroxisome proliferator-activated receptor-γ coactivator 1α in skeletal muscle cells involves MEK1/2 and nuclear factor-κB activation
    • DOI 10.2337/db05-1494
    • Palmitate mediated downregulation of peroxisome proliferator-activated receptor-gamma coactivator 1alpha in skeletal muscle cells involves MEK1/2 and nuclear factor-kappaB activation. Coll T, Jove M, Rodriguez-Calvo R, Eyre E, Palomer X, Sanchez RM, Merlos M, Laguna JC, Vazquez-Carrera M, Diabetes 2006 55 2779 2787 10.2337/db05-1494 17003343 (Pubitemid 44923677)
    • (2006) Diabetes , vol.55 , Issue.10 , pp. 2779-2787
    • Coll, T.1    Jove, M.2    Rodriguez-Calvo, R.3    Eyre, E.4    Palomer, X.5    Sanchez, R.M.6    Merlos, M.7    Laguna, J.C.8    Vazquez-Carrera, M.9


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