-
1
-
-
13444301307
-
Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences
-
Dudley D.D., Chaudhuri J., Bassing C.H., Alt F.W. Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences. Adv. Immunol. 2005, 86:43-112.
-
(2005)
Adv. Immunol.
, vol.86
, pp. 43-112
-
-
Dudley, D.D.1
Chaudhuri, J.2
Bassing, C.H.3
Alt, F.W.4
-
3
-
-
70349574619
-
Recent insights into the formation of RAG-induced chromosomal translocations
-
Brandt V.L., Roth D.B. Recent insights into the formation of RAG-induced chromosomal translocations. Adv. Exp. Med. Biol. 2009, 650:32-45.
-
(2009)
Adv. Exp. Med. Biol.
, vol.650
, pp. 32-45
-
-
Brandt, V.L.1
Roth, D.B.2
-
4
-
-
80355122714
-
V(D)J recombination: mechanisms of initiation
-
Schatz D.G., Swanson P.C. V(D)J recombination: mechanisms of initiation. Annu. Rev. Genet. 2011, 45:167-202.
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 167-202
-
-
Schatz, D.G.1
Swanson, P.C.2
-
6
-
-
0038293484
-
Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
-
Ramiro A.R., Stavropoulos P., Jankovic M., Nussenzweig M.C. Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand. Nat. Immunol. 2003, 4:452-456.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 452-456
-
-
Ramiro, A.R.1
Stavropoulos, P.2
Jankovic, M.3
Nussenzweig, M.C.4
-
7
-
-
0037452080
-
Transcription-targeted DNA deamination by the AID antibody diversification enzyme
-
Chaudhuri J., Tian M., Khuong C., Chua K., Pinaud E., Alt F.W. Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature 2003, 422:726-730.
-
(2003)
Nature
, vol.422
, pp. 726-730
-
-
Chaudhuri, J.1
Tian, M.2
Khuong, C.3
Chua, K.4
Pinaud, E.5
Alt, F.W.6
-
8
-
-
77950955761
-
Origin of chromosomal translocations in lymphoid cancer
-
Nussenzweig A., Nussenzweig M.C. Origin of chromosomal translocations in lymphoid cancer. Cell 2010, 141:27-38.
-
(2010)
Cell
, vol.141
, pp. 27-38
-
-
Nussenzweig, A.1
Nussenzweig, M.C.2
-
9
-
-
79953032797
-
Mechanisms that promote and suppress chromosomal translocations in lymphocytes
-
Gostissa M., Alt F.W., Chiarle R. Mechanisms that promote and suppress chromosomal translocations in lymphocytes. Annu. Rev. Immunol. 2011, 29:319-350.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 319-350
-
-
Gostissa, M.1
Alt, F.W.2
Chiarle, R.3
-
10
-
-
16844381831
-
Mechanisms of B-cell lymphoma pathogenesis
-
Kuppers R. Mechanisms of B-cell lymphoma pathogenesis. Nat. Rev. Cancer 2005, 5:251-262.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 251-262
-
-
Kuppers, R.1
-
11
-
-
0021983551
-
Developmentally controlled and tissue-specific expression of unrearranged VH gene segments
-
Yancopoulos G.D., Alt F.W. Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell 1985, 40:271-281.
-
(1985)
Cell
, vol.40
, pp. 271-281
-
-
Yancopoulos, G.D.1
Alt, F.W.2
-
12
-
-
0037625160
-
Gene segment selection in V(D)J recombination: accessibility and beyond
-
Krangel M.S. Gene segment selection in V(D)J recombination: accessibility and beyond. Nat. Immunol. 2003, 4:624-630.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 624-630
-
-
Krangel, M.S.1
-
13
-
-
0022599997
-
Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching
-
Stavnezer-Nordgren J., Sirlin S. Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching. EMBO J. 1986, 5:95-102.
-
(1986)
EMBO J.
, vol.5
, pp. 95-102
-
-
Stavnezer-Nordgren, J.1
Sirlin, S.2
-
14
-
-
0023020765
-
Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching
-
Yancopoulos G.D., DePinho R.A., Zimmerman K.A., Lutzker S.G., Rosenberg N., Alt F.W. Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching. EMBO J. 1986, 5:3259-3266.
-
(1986)
EMBO J.
, vol.5
, pp. 3259-3266
-
-
Yancopoulos, G.D.1
DePinho, R.A.2
Zimmerman, K.A.3
Lutzker, S.G.4
Rosenberg, N.5
Alt, F.W.6
-
15
-
-
34249793250
-
The role of activation-induced deaminase in antibody diversification and chromosome translocations
-
Ramiro A., Reina San-Martin B., McBride K., Jankovic M., Barreto V., Nussenzweig A., Nussenzweig M.C. The role of activation-induced deaminase in antibody diversification and chromosome translocations. Adv. Immunol. 2007, 94:75-107.
-
(2007)
Adv. Immunol.
, vol.94
, pp. 75-107
-
-
Ramiro, A.1
Reina San-Martin, B.2
McBride, K.3
Jankovic, M.4
Barreto, V.5
Nussenzweig, A.6
Nussenzweig, M.C.7
-
16
-
-
33747849302
-
Accessibility control of V(D)J recombination
-
Cobb R.M., Oestreich K.J., Osipovich O.A., Oltz E.M. Accessibility control of V(D)J recombination. Adv. Immunol. 2006, 91:45-109.
-
(2006)
Adv. Immunol.
, vol.91
, pp. 45-109
-
-
Cobb, R.M.1
Oestreich, K.J.2
Osipovich, O.A.3
Oltz, E.M.4
-
17
-
-
0032858194
-
Molecular processes that regulate class switching
-
Stavnezer J. Molecular processes that regulate class switching. Curr. Top. Microbiol. Immunol. 2000, 245:127-168.
-
(2000)
Curr. Top. Microbiol. Immunol.
, vol.245
, pp. 127-168
-
-
Stavnezer, J.1
-
18
-
-
68049086918
-
Chromatin architecture and the generation of antigen receptor diversity
-
Jhunjhunwala S., van Zelm M.C., Peak M.M., Murre C. Chromatin architecture and the generation of antigen receptor diversity. Cell 2009, 138:435-448.
-
(2009)
Cell
, vol.138
, pp. 435-448
-
-
Jhunjhunwala, S.1
van Zelm, M.C.2
Peak, M.M.3
Murre, C.4
-
19
-
-
77955860807
-
Chromosome dynamics and the regulation of V(D)J recombination
-
Hewitt S.L., Chaumeil J., Skok J.A. Chromosome dynamics and the regulation of V(D)J recombination. Immunol. Rev. 2010, 237:43-54.
-
(2010)
Immunol. Rev.
, vol.237
, pp. 43-54
-
-
Hewitt, S.L.1
Chaumeil, J.2
Skok, J.A.3
-
20
-
-
70349571324
-
Molecular pathways and mechanisms regulating the recombination of immunoglobulin genes during B-lymphocyte development
-
Johnson K., Reddy K.L., Singh H. Molecular pathways and mechanisms regulating the recombination of immunoglobulin genes during B-lymphocyte development. Adv. Exp. Med. Biol. 2009, 650:133-147.
-
(2009)
Adv. Exp. Med. Biol.
, vol.650
, pp. 133-147
-
-
Johnson, K.1
Reddy, K.L.2
Singh, H.3
-
21
-
-
0038148400
-
Chromatin dynamics and locus accessibility in the immune system
-
Mostoslavsky R., Alt F.W., Bassing C.H. Chromatin dynamics and locus accessibility in the immune system. Nat. Immunol. 2003, 4:603-606.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 603-606
-
-
Mostoslavsky, R.1
Alt, F.W.2
Bassing, C.H.3
-
22
-
-
0033638506
-
Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA
-
Kwon J., Morshead K.B., Guyon J.R., Kingston R.E., Oettinger M.A. Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA. Mol. Cell 2000, 6:1037-1048.
-
(2000)
Mol. Cell
, vol.6
, pp. 1037-1048
-
-
Kwon, J.1
Morshead, K.B.2
Guyon, J.R.3
Kingston, R.E.4
Oettinger, M.A.5
-
23
-
-
50249154114
-
Activation of 12/23-RSS-dependent RAG cleavage by hSWI/SNF complex in the absence of transcription
-
Du H., Ishii H., Pazin M.J., Sen R. Activation of 12/23-RSS-dependent RAG cleavage by hSWI/SNF complex in the absence of transcription. Mol. Cell 2008, 31:641-649.
-
(2008)
Mol. Cell
, vol.31
, pp. 641-649
-
-
Du, H.1
Ishii, H.2
Pazin, M.J.3
Sen, R.4
-
24
-
-
85015069067
-
Controlling the double helix
-
Felsenfeld G., Groudine M. Controlling the double helix. Nature 2003, 421:448-453.
-
(2003)
Nature
, vol.421
, pp. 448-453
-
-
Felsenfeld, G.1
Groudine, M.2
-
25
-
-
36448949026
-
Multivalent engagement of chromatin modifications by linked binding modules
-
Ruthenburg A.J., Li H., Patel D.J., Allis C.D. Multivalent engagement of chromatin modifications by linked binding modules. Nat. Rev. Mol. Cell Biol. 2007, 8:983-994.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 983-994
-
-
Ruthenburg, A.J.1
Li, H.2
Patel, D.J.3
Allis, C.D.4
-
26
-
-
0035839136
-
Translating the histone code
-
Jenuwein T., Allis C.D. Translating the histone code. Science 2001, 293:1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
27
-
-
8844248619
-
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage
-
Sanders S.L., Portoso M., Mata J., Bahler J., Allshire R.C., Kouzarides T. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 2004, 119:603-614.
-
(2004)
Cell
, vol.119
, pp. 603-614
-
-
Sanders, S.L.1
Portoso, M.2
Mata, J.3
Bahler, J.4
Allshire, R.C.5
Kouzarides, T.6
-
28
-
-
30744465308
-
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals
-
Lou Z., Minter-Dykhouse K., Franco S., Gostissa M., Rivera M.A., Celeste A., Manis J.P., van Deursen J., Nussenzweig A., Paull T.T., Alt F.W., Chen J. MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. Mol. Cell 2006, 21:187-200.
-
(2006)
Mol. Cell
, vol.21
, pp. 187-200
-
-
Lou, Z.1
Minter-Dykhouse, K.2
Franco, S.3
Gostissa, M.4
Rivera, M.A.5
Celeste, A.6
Manis, J.P.7
van Deursen, J.8
Nussenzweig, A.9
Paull, T.T.10
Alt, F.W.11
Chen, J.12
-
29
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki M., Clapperton J.A., Mohammad D., Yaffe M.B., Smerdon S.J., Jackson S.P. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 2005, 123:1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
30
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan M.V., Lee J., Ward I.M., Kim J.E., Thompson J.R., Chen J., Mer G. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 2006, 127:1361-1373.
-
(2006)
Cell
, vol.127
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
31
-
-
0141705373
-
Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4
-
Morshead K.B., Ciccone D.N., Taverna S.D., Allis C.D., Oettinger M.A. Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:11577-11582.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 11577-11582
-
-
Morshead, K.B.1
Ciccone, D.N.2
Taverna, S.D.3
Allis, C.D.4
Oettinger, M.A.5
-
32
-
-
3042750473
-
Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition
-
Perkins E.J., Kee B.L., Ramsden D.A. Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition. Nucleic Acids Res. 2004, 32:1942-1947.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1942-1947
-
-
Perkins, E.J.1
Kee, B.L.2
Ramsden, D.A.3
-
33
-
-
33846019277
-
Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark
-
Ruthenburg A.J., Allis C.D., Wysocka J. Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol. Cell 2007, 25:15-30.
-
(2007)
Mol. Cell
, vol.25
, pp. 15-30
-
-
Ruthenburg, A.J.1
Allis, C.D.2
Wysocka, J.3
-
34
-
-
0344022572
-
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity
-
Ng H.H., Robert F., Young R.A., Struhl K. Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity. Mol. Cell 2003, 11:709-719.
-
(2003)
Mol. Cell
, vol.11
, pp. 709-719
-
-
Ng, H.H.1
Robert, F.2
Young, R.A.3
Struhl, K.4
-
35
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells
-
Guenther M.G., Levine S.S., Boyer L.A., Jaenisch R., Young R.A. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 2007, 130:77-88.
-
(2007)
Cell
, vol.130
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
37
-
-
33746324216
-
Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression
-
Shilatifard A. Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu. Rev. Biochem. 2006, 75:243-269.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 243-269
-
-
Shilatifard, A.1
-
38
-
-
65249105512
-
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
-
Kim J., Guermah M., McGinty R.K., Lee J.S., Tang Z., Milne T.A., Shilatifard A., Muir T.W., Roeder R.G. RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 2009, 137:459-471.
-
(2009)
Cell
, vol.137
, pp. 459-471
-
-
Kim, J.1
Guermah, M.2
McGinty, R.K.3
Lee, J.S.4
Tang, Z.5
Milne, T.A.6
Shilatifard, A.7
Muir, T.W.8
Roeder, R.G.9
-
39
-
-
37249041657
-
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination
-
Matthews A.G., Kuo A.J., Ramon-Maiques S., Han S., Champagne K.S., Ivanov D., Gallardo M., Carney D., Cheung P., Ciccone D.N., Walter K.L., Utz P.J., Shi Y., Kutateladze T.G., Yang W., Gozani O., Oettinger M.A. RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. Nature 2007, 450:1106-1110.
-
(2007)
Nature
, vol.450
, pp. 1106-1110
-
-
Matthews, A.G.1
Kuo, A.J.2
Ramon-Maiques, S.3
Han, S.4
Champagne, K.S.5
Ivanov, D.6
Gallardo, M.7
Carney, D.8
Cheung, P.9
Ciccone, D.N.10
Walter, K.L.11
Utz, P.J.12
Shi, Y.13
Kutateladze, T.G.14
Yang, W.15
Gozani, O.16
Oettinger, M.A.17
-
40
-
-
35349024178
-
A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement
-
Liu Y., Subrahmanyam R., Chakraborty T., Sen R., Desiderio S. A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity 2007, 27:561-571.
-
(2007)
Immunity
, vol.27
, pp. 561-571
-
-
Liu, Y.1
Subrahmanyam, R.2
Chakraborty, T.3
Sen, R.4
Desiderio, S.5
-
41
-
-
37649026007
-
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2
-
Ramon-Maiques S., Kuo A.J., Carney D., Matthews A.G., Oettinger M.A., Gozani O., Yang W. The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:18993-18998.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 18993-18998
-
-
Ramon-Maiques, S.1
Kuo, A.J.2
Carney, D.3
Matthews, A.G.4
Oettinger, M.A.5
Gozani, O.6
Yang, W.7
-
42
-
-
77951893700
-
The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci
-
Ji Y., Resch W., Corbett E., Yamane A., Casellas R., Schatz D.G. The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci. Cell 2010, 141:419-431.
-
(2010)
Cell
, vol.141
, pp. 419-431
-
-
Ji, Y.1
Resch, W.2
Corbett, E.3
Yamane, A.4
Casellas, R.5
Schatz, D.G.6
-
43
-
-
66749124789
-
H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations
-
Shimazaki N., Tsai A.G., Lieber M.R. H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations. Mol. Cell 2009, 34:535-544.
-
(2009)
Mol. Cell
, vol.34
, pp. 535-544
-
-
Shimazaki, N.1
Tsai, A.G.2
Lieber, M.R.3
-
44
-
-
78651089760
-
Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination
-
Grundy G.J., Yang W., Gellert M. Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:22487-22492.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 22487-22492
-
-
Grundy, G.J.1
Yang, W.2
Gellert, M.3
-
45
-
-
77951163493
-
Analysis of mutations from SCID and Omenn syndrome patients reveals the central role of the Rag2 PHD domain in regulating V(D)J recombination
-
Couedel C., Roman C., Jones A., Vezzoni P., Villa A., Cortes P. Analysis of mutations from SCID and Omenn syndrome patients reveals the central role of the Rag2 PHD domain in regulating V(D)J recombination. J. Clin. Invest. 2010, 120:1337-1344.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1337-1344
-
-
Couedel, C.1
Roman, C.2
Jones, A.3
Vezzoni, P.4
Villa, A.5
Cortes, P.6
-
46
-
-
0346362489
-
Transcription-coupled events associating with immunoglobulin switch region chromatin
-
Nambu Y., Sugai M., Gonda H., Lee C.G., Katakai T., Agata Y., Yokota Y., Shimizu A. Transcription-coupled events associating with immunoglobulin switch region chromatin. Science 2003, 302:2137-2140.
-
(2003)
Science
, vol.302
, pp. 2137-2140
-
-
Nambu, Y.1
Sugai, M.2
Gonda, H.3
Lee, C.G.4
Katakai, T.5
Agata, Y.6
Yokota, Y.7
Shimizu, A.8
-
47
-
-
77957239251
-
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5
-
Pavri R., Gazumyan A., Jankovic M., Di Virgilio M., Klein I., Ansarah-Sobrinho C., Resch W., Yamane A., Reina San-Martin B., Barreto V., Nieland T.J., Root D.E., Casellas R., Nussenzweig M.C. Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell 2010, 143:122-133.
-
(2010)
Cell
, vol.143
, pp. 122-133
-
-
Pavri, R.1
Gazumyan, A.2
Jankovic, M.3
Di Virgilio, M.4
Klein, I.5
Ansarah-Sobrinho, C.6
Resch, W.7
Yamane, A.8
Reina San-Martin, B.9
Barreto, V.10
Nieland, T.J.11
Root, D.E.12
Casellas, R.13
Nussenzweig, M.C.14
-
48
-
-
79551681406
-
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates
-
Basu U., Meng F.L., Keim C., Grinstein V., Pefanis E., Eccleston J., Zhang T., Myers D., Wasserman C.R., Wesemann D.R., Januszyk K., Gregory R.I., Deng H., Lima C.D., Alt F.W. The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell 2011, 144:353-363.
-
(2011)
Cell
, vol.144
, pp. 353-363
-
-
Basu, U.1
Meng, F.L.2
Keim, C.3
Grinstein, V.4
Pefanis, E.5
Eccleston, J.6
Zhang, T.7
Myers, D.8
Wasserman, C.R.9
Wesemann, D.R.10
Januszyk, K.11
Gregory, R.I.12
Deng, H.13
Lima, C.D.14
Alt, F.W.15
-
49
-
-
31344445404
-
AID-dependent histone acetylation is detected in immunoglobulin S regions
-
Wang L., Whang N., Wuerffel R., Kenter A.L. AID-dependent histone acetylation is detected in immunoglobulin S regions. J. Exp. Med. 2006, 203:215-226.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 215-226
-
-
Wang, L.1
Whang, N.2
Wuerffel, R.3
Kenter, A.L.4
-
50
-
-
7444234734
-
Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching
-
Li Z., Luo Z., Scharff M.D. Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:15428-15433.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15428-15433
-
-
Li, Z.1
Luo, Z.2
Scharff, M.D.3
-
51
-
-
57349114640
-
Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus
-
Chowdhury M., Forouhi O., Dayal S., McCloskey N., Gould H.J., Felsenfeld G., Fear D.J. Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:15872-15877.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 15872-15877
-
-
Chowdhury, M.1
Forouhi, O.2
Dayal, S.3
McCloskey, N.4
Gould, H.J.5
Felsenfeld, G.6
Fear, D.J.7
-
52
-
-
68149158825
-
S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination
-
Wang L., Wuerffel R., Feldman S., Khamlichi A.A., Kenter A.L. S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination. J. Exp. Med. 2009, 206:1817-1830.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1817-1830
-
-
Wang, L.1
Wuerffel, R.2
Feldman, S.3
Khamlichi, A.A.4
Kenter, A.L.5
-
53
-
-
65249129851
-
H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination
-
Kuang F.L., Luo Z., Scharff M.D. H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:5288-5293.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 5288-5293
-
-
Kuang, F.L.1
Luo, Z.2
Scharff, M.D.3
-
54
-
-
78650308767
-
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes
-
Yamane A., Resch W., Kuo N., Kuchen S., Li Z., Sun H.W., Robbiani D.F., McBride K., Nussenzweig M.C., Casellas R. Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes. Nat. Immunol. 2011, 12:62-69.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 62-69
-
-
Yamane, A.1
Resch, W.2
Kuo, N.3
Kuchen, S.4
Li, Z.5
Sun, H.W.6
Robbiani, D.F.7
McBride, K.8
Nussenzweig, M.C.9
Casellas, R.10
-
56
-
-
79961150210
-
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
-
Jeevan-Raj B.P., Robert I., Heyer V., Page A., Wang J.H., Cammas F., Alt F.W., Losson R., Reina-San-Martin B. Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination. J. Exp. Med. 2011, 208:1649-1660.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1649-1660
-
-
Jeevan-Raj, B.P.1
Robert, I.2
Heyer, V.3
Page, A.4
Wang, J.H.5
Cammas, F.6
Alt, F.W.7
Losson, R.8
Reina-San-Martin, B.9
-
57
-
-
33745829068
-
The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA
-
Bradley S.P., Kaminski D.A., Peters A.H., Jenuwein T., Stavnezer J. The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA. J. Immunol. 2006, 177:1179-1188.
-
(2006)
J. Immunol.
, vol.177
, pp. 1179-1188
-
-
Bradley, S.P.1
Kaminski, D.A.2
Peters, A.H.3
Jenuwein, T.4
Stavnezer, J.5
-
58
-
-
0027279628
-
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations
-
Thirman M.J., Gill H.J., Burnett R.C., Mbangkollo D., McCabe N.R., Kobayashi H., Ziemin-van der Poel S., Kaneko Y., Morgan R., Sandberg A.A., et al. Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N. Engl. J. Med. 1993, 329:909-914.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 909-914
-
-
Thirman, M.J.1
Gill, H.J.2
Burnett, R.C.3
Mbangkollo, D.4
McCabe, N.R.5
Kobayashi, H.6
Ziemin-van der Poel, S.7
Kaneko, Y.8
Morgan, R.9
Sandberg, A.A.10
-
59
-
-
76749139057
-
The histone demethylase UTX enables RB-dependent cell fate control
-
Wang J.K., Tsai M.C., Poulin G., Adler A.S., Chen S., Liu H., Shi Y., Chang H.Y. The histone demethylase UTX enables RB-dependent cell fate control. Genes Dev. 2010, 24:327-332.
-
(2010)
Genes Dev.
, vol.24
, pp. 327-332
-
-
Wang, J.K.1
Tsai, M.C.2
Poulin, G.3
Adler, A.S.4
Chen, S.5
Liu, H.6
Shi, Y.7
Chang, H.Y.8
-
60
-
-
0037672689
-
An epigenetic road map for histone lysine methylation
-
Lachner M., O'Sullivan R.J., Jenuwein T. An epigenetic road map for histone lysine methylation. J. Cell Sci. 2003, 116:2117-2124.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2117-2124
-
-
Lachner, M.1
O'Sullivan, R.J.2
Jenuwein, T.3
-
61
-
-
77955866537
-
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
-
Daniel J.A., Santos M.A., Wang Z., Zang C., Schwab K.R., Jankovic M., Filsuf D., Chen H.T., Gazumyan A., Yamane A., Cho Y.W., Sun H.W., Ge K., Peng W., Nussenzweig M.C., Casellas R., Dressler G.R., Zhao K., Nussenzweig A. PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. Science 2010.
-
(2010)
Science
-
-
Daniel, J.A.1
Santos, M.A.2
Wang, Z.3
Zang, C.4
Schwab, K.R.5
Jankovic, M.6
Filsuf, D.7
Chen, H.T.8
Gazumyan, A.9
Yamane, A.10
Cho, Y.W.11
Sun, H.W.12
Ge, K.13
Peng, W.14
Nussenzweig, M.C.15
Casellas, R.16
Dressler, G.R.17
Zhao, K.18
Nussenzweig, A.19
-
62
-
-
34547122520
-
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex
-
Cho Y.W., Hong T., Hong S., Guo H., Yu H., Kim D., Guszczynski T., Dressler G.R., Copeland T.D., Kalkum M., Ge K. PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. J. Biol. Chem. 2007, 282:20395-20406.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20395-20406
-
-
Cho, Y.W.1
Hong, T.2
Hong, S.3
Guo, H.4
Yu, H.5
Kim, D.6
Guszczynski, T.7
Dressler, G.R.8
Copeland, T.D.9
Kalkum, M.10
Ge, K.11
-
63
-
-
34848880490
-
The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex
-
Patel S.R., Kim D., Levitan I., Dressler G.R. The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex. Dev. Cell 2007, 13:580-592.
-
(2007)
Dev. Cell
, vol.13
, pp. 580-592
-
-
Patel, S.R.1
Kim, D.2
Levitan, I.3
Dressler, G.R.4
-
64
-
-
33847219608
-
Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth
-
Issaeva I., Zonis Y., Rozovskaia T., Orlovsky K., Croce C.M., Nakamura T., Mazo A., Eisenbach L., Canaani E. Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth. Mol. Cell. Biol. 2007, 27:1889-1903.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1889-1903
-
-
Issaeva, I.1
Zonis, Y.2
Rozovskaia, T.3
Orlovsky, K.4
Croce, C.M.5
Nakamura, T.6
Mazo, A.7
Eisenbach, L.8
Canaani, E.9
-
65
-
-
79953769946
-
Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locus
-
Schwab K.R., Patel S.R., Dressler G.R. Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locus. Mol. Cell. Biol. 2011, 31:1503-1511.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1503-1511
-
-
Schwab, K.R.1
Patel, S.R.2
Dressler, G.R.3
-
66
-
-
61849141219
-
Control of histone methylation and genome stability by PTIP
-
Munoz I.M., Rouse J. Control of histone methylation and genome stability by PTIP. EMBO Rep. 2009, 10:239-245.
-
(2009)
EMBO Rep.
, vol.10
, pp. 239-245
-
-
Munoz, I.M.1
Rouse, J.2
-
67
-
-
0034662007
-
PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin
-
Lechner M.S., Levitan I., Dressler G.R. PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin. Nucleic Acids Res. 2000, 28:2741-2751.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2741-2751
-
-
Lechner, M.S.1
Levitan, I.2
Dressler, G.R.3
-
68
-
-
0035024425
-
Swift is a novel BRCT domain coactivator of Smad2 in transforming growth factor beta signaling
-
Shimizu K., Bourillot P.Y., Nielsen S.J., Zorn A.M., Gurdon J.B. Swift is a novel BRCT domain coactivator of Smad2 in transforming growth factor beta signaling. Mol. Cell. Biol. 2001, 21:3901-3912.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3901-3912
-
-
Shimizu, K.1
Bourillot, P.Y.2
Nielsen, S.J.3
Zorn, A.M.4
Gurdon, J.B.5
-
69
-
-
0029998777
-
B cell lineage-specific activator protein (BSAP). A player at multiple stages of B cell development
-
Michaelson J.S., Singh M., Birshtein B.K. B cell lineage-specific activator protein (BSAP). A player at multiple stages of B cell development. J. Immunol. 1996, 156:2349-2351.
-
(1996)
J. Immunol.
, vol.156
, pp. 2349-2351
-
-
Michaelson, J.S.1
Singh, M.2
Birshtein, B.K.3
-
70
-
-
34247188078
-
Pax5: the guardian of B cell identity and function
-
Cobaleda C., Schebesta A., Delogu A., Busslinger M. Pax5: the guardian of B cell identity and function. Nat. Immunol. 2007, 8:463-470.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 463-470
-
-
Cobaleda, C.1
Schebesta, A.2
Delogu, A.3
Busslinger, M.4
-
71
-
-
0028196601
-
The B cell-specific transcription factor BSAP regulates B cell proliferation
-
Wakatsuki Y., Neurath M.F., Max E.E., Strober W. The B cell-specific transcription factor BSAP regulates B cell proliferation. J. Exp. Med. 1994, 179:1099-1108.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1099-1108
-
-
Wakatsuki, Y.1
Neurath, M.F.2
Max, E.E.3
Strober, W.4
-
72
-
-
65149092552
-
Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage
-
Gong Z., Cho Y.W., Kim J.E., Ge K., Chen J. Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage. J. Biol. Chem. 2009, 284:7284-7293.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 7284-7293
-
-
Gong, Z.1
Cho, Y.W.2
Kim, J.E.3
Ge, K.4
Chen, J.5
-
73
-
-
78650666372
-
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
-
Stanlie A., Aida M., Muramatsu M., Honjo T., Begum N.A. Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:22190-22195.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 22190-22195
-
-
Stanlie, A.1
Aida, M.2
Muramatsu, M.3
Honjo, T.4
Begum, N.A.5
-
74
-
-
67449161835
-
Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation
-
Rajagopal D., Maul R.W., Ghosh A., Chakraborty T., Khamlichi A.A., Sen R., Gearhart P.J. Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation. J. Exp. Med. 2009, 206:1237-1244.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1237-1244
-
-
Rajagopal, D.1
Maul, R.W.2
Ghosh, A.3
Chakraborty, T.4
Khamlichi, A.A.5
Sen, R.6
Gearhart, P.J.7
-
75
-
-
77956642100
-
Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome
-
Ng S.B., Bigham A.W., Buckingham K.J., Hannibal M.C., McMillin M.J., Gildersleeve H.I., Beck A.E., Tabor H.K., Cooper G.M., Mefford H.C., Lee C., Turner E.H., Smith J.D., Rieder M.J., Yoshiura K., Matsumoto N., Ohta T., Niikawa N., Nickerson D.A., Bamshad M.J., Shendure J. Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome. Nat. Genet. 2010, 42:790-793.
-
(2010)
Nat. Genet.
, vol.42
, pp. 790-793
-
-
Ng, S.B.1
Bigham, A.W.2
Buckingham, K.J.3
Hannibal, M.C.4
McMillin, M.J.5
Gildersleeve, H.I.6
Beck, A.E.7
Tabor, H.K.8
Cooper, G.M.9
Mefford, H.C.10
Lee, C.11
Turner, E.H.12
Smith, J.D.13
Rieder, M.J.14
Yoshiura, K.15
Matsumoto, N.16
Ohta, T.17
Niikawa, N.18
Nickerson, D.A.19
Bamshad, M.J.20
Shendure, J.21
more..
-
76
-
-
19944420858
-
Immune abnormalities are a frequent manifestation of Kabuki syndrome
-
Hoffman J.D., Ciprero K.L., Sullivan K.E., Kaplan P.B., McDonald-McGinn D.M., Zackai E.H., Ming J.E. Immune abnormalities are a frequent manifestation of Kabuki syndrome. Am. J. Med. Genet. A 2005, 135:278-281.
-
(2005)
Am. J. Med. Genet. A
, vol.135
, pp. 278-281
-
-
Hoffman, J.D.1
Ciprero, K.L.2
Sullivan, K.E.3
Kaplan, P.B.4
McDonald-McGinn, D.M.5
Zackai, E.H.6
Ming, J.E.7
-
77
-
-
80052269038
-
Analysis of the coding genome of diffuse large B-cell lymphoma
-
Pasqualucci L., Trifonov V., Fabbri G., Ma J., Rossi D., Chiarenza A., Wells V.A., Grunn A., Messina M., Elliot O., Chan J., Bhagat G., Chadburn A., Gaidano G., Mullighan C.G., Rabadan R., Dalla-Favera R. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat. Genet. 2011, 43:830-837.
-
(2011)
Nat. Genet.
, vol.43
, pp. 830-837
-
-
Pasqualucci, L.1
Trifonov, V.2
Fabbri, G.3
Ma, J.4
Rossi, D.5
Chiarenza, A.6
Wells, V.A.7
Grunn, A.8
Messina, M.9
Elliot, O.10
Chan, J.11
Bhagat, G.12
Chadburn, A.13
Gaidano, G.14
Mullighan, C.G.15
Rabadan, R.16
Dalla-Favera, R.17
-
78
-
-
80052029516
-
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
-
Morin R.D., Mendez-Lago M., Mungall A.J., Goya R., Mungall K.L., Corbett R.D., Johnson N.A., Severson T.M., Chiu R., Field M., Jackman S., Krzywinski M., Scott D.W., Trinh D.L., Tamura-Wells J., Li S., Firme M.R., Rogic S., Griffith M., Chan S., Yakovenko O., Meyer I.M., Zhao E.Y., Smailus D., Moksa M., Chittaranjan S., Rimsza L., Brooks-Wilson A., Spinelli J.J., Ben-Neriah S., Meissner B., Woolcock B., Boyle M., McDonald H., Tam A., Zhao Y., Delaney A., Zeng T., Tse K., Butterfield Y., Birol I., Holt R., Schein J., Horsman D.E., Moore R., Jones S.J., Connors J.M., Hirst M., Gascoyne R.D., Marra M.A. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature 2011, 476:298-303.
-
(2011)
Nature
, vol.476
, pp. 298-303
-
-
Morin, R.D.1
Mendez-Lago, M.2
Mungall, A.J.3
Goya, R.4
Mungall, K.L.5
Corbett, R.D.6
Johnson, N.A.7
Severson, T.M.8
Chiu, R.9
Field, M.10
Jackman, S.11
Krzywinski, M.12
Scott, D.W.13
Trinh, D.L.14
Tamura-Wells, J.15
Li, S.16
Firme, M.R.17
Rogic, S.18
Griffith, M.19
Chan, S.20
Yakovenko, O.21
Meyer, I.M.22
Zhao, E.Y.23
Smailus, D.24
Moksa, M.25
Chittaranjan, S.26
Rimsza, L.27
Brooks-Wilson, A.28
Spinelli, J.J.29
Ben-Neriah, S.30
Meissner, B.31
Woolcock, B.32
Boyle, M.33
McDonald, H.34
Tam, A.35
Zhao, Y.36
Delaney, A.37
Zeng, T.38
Tse, K.39
Butterfield, Y.40
Birol, I.41
Holt, R.42
Schein, J.43
Horsman, D.E.44
Moore, R.45
Jones, S.J.46
Connors, J.M.47
Hirst, M.48
Gascoyne, R.D.49
Marra, M.A.50
more..
|