Rapid desensitization of somatodendritic 5-HT 1A receptors by chronic administration of the high-efficacy 5-HT 1A agonist, F13714: A microdialysis study in the rat

British Journal of Pharmacology

Volumn 149, Issue 2, 2006, Pages 170-178

  Assie M B ^a   Lomenech, H ^a   Ravailhe, V ^a   Faucillon, V ^a   Newman Tancredi, A ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

5 HT 1A receptors; Chronic administration; Extracellular 5 HT concentration; F13714; Flesinoxan; Microdialysis; Osmotic pumps

Indexed keywords

3 CHLORO 4 FLUOROPHENYL [4 FLUORO 4 [(5 METHYL 6 METHYLAMINOPYRIDIN 2 YLMETHYL)AMINO]METHYL]PIPERIDIN 1 YLMETHANONE; ANTIDEPRESSANT AGENT; AUTORECEPTOR; BUSPIRONE; CITALOPRAM; F 13714; FLESINOXAN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PARTIAL AGONIST; PIPERIDINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ACUTE DRUG ADMINISTRATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; ELECTROCHEMICAL DETECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; MALE; MICRODIALYSIS; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; SEROTONIN RELEASE;

AMINOPYRIDINES; ANIMALS; BUSPIRONE; HIPPOCAMPUS; MALE; MICRODIALYSIS; PIPERAZINES; PIPERIDINES; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN; SEROTONIN 5-HT1 RECEPTOR AGONISTS; SEROTONIN AGONISTS; SEROTONIN RECEPTOR AGONISTS;

EID: 33748493597     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706859     Document Type: Article

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