Synthesis and evaluation of 11C-labeled (S)-N-{[1-(2-phenylethyl) pyrrolidin-2-yl]methyl}-3-methylthiobenzamide as a PET 5-HT1A receptor ligand

Nuclear Medicine and Biology

Volumn 29, Issue 6, 2002, Pages 657-663

  Fujio, Masakazu ^a   Nagata, Shinji ^b,c   Kawamura, Kazunori ^b   Sugiyama, Naoki ^a   Tanaka, Hiroshi ^a   Uno, Kimiichi ^c   Ishiwata, Kiichi ^b  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c Nishidai Clinic   (Japan)

Author keywords

5 HT1A receptor; Carbon 11; Positron emission tomography; PPMMB

Indexed keywords

BENZAMIDE DERIVATIVE; DIMER; DISULFIDE; N [[1 (2 PHENYLETHYL)PYRROLIDIN 2 YL]METHYL] 3 METHYLTHIOBENZAMIDE C 11; RADIOLIGAND; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BRAIN REGION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; MALE; METHYLATION; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; REDUCTION;

ANIMALS; BENZAMIDES; BRAIN; MALE; MICE; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SULFIDES; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036701656     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(02)00305-0     Document Type: Article

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