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Volumn 1819, Issue 7, 2012, Pages 757-762

The ghosts in the machine: DNA methylation and the mystery of differentiation

Author keywords

DNA methylation; Embryogenesis; SNF2

Indexed keywords

DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; HELICASE; KRUPPEL LIKE FACTOR 4; LYMPHOID SPECIFIC HELICASE; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SNF; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

EID: 84861872488     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2012.02.013     Document Type: Review
Times cited : (10)

References (73)
  • 1
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modification: patterns and paradigms
    • Cedar H., Bergman Y. Linking DNA methylation and histone modification: patterns and paradigms. Nat. Rev. Genet. 2009, 10:295-304.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 2
    • 70350028850 scopus 로고    scopus 로고
    • Mammalian cytosine methylation at a glance
    • Ooi S.K., O'Donnell A.H., Bestor T.H. Mammalian cytosine methylation at a glance. J. Cell Sci. 2009, 122:2787-2791.
    • (2009) J. Cell Sci. , vol.122 , pp. 2787-2791
    • Ooi, S.K.1    O'Donnell, A.H.2    Bestor, T.H.3
  • 5
    • 77952355762 scopus 로고    scopus 로고
    • Genome-wide evolutionary analysis of eukaryotic DNA methylation
    • Zemach A., McDaniel I.E., Silva P., Zilberman D. Genome-wide evolutionary analysis of eukaryotic DNA methylation. Science 2010, 328:916-919.
    • (2010) Science , vol.328 , pp. 916-919
    • Zemach, A.1    McDaniel, I.E.2    Silva, P.3    Zilberman, D.4
  • 6
    • 73249144150 scopus 로고    scopus 로고
    • DNA methylation in early development
    • Geiman T.M., Muegge K. DNA methylation in early development. Mol. Reprod. Dev. 2010, 77:105-113.
    • (2010) Mol. Reprod. Dev. , vol.77 , pp. 105-113
    • Geiman, T.M.1    Muegge, K.2
  • 7
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 2007, 447:425-432.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 10
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E., Bestor T.H., Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69:915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 11
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M., Bell D.W., Haber D.A., Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 14
    • 80053144962 scopus 로고    scopus 로고
    • A decade of exploring the cancer epigenome-biological and translational implications
    • Baylin S.B., Jones P.A. A decade of exploring the cancer epigenome-biological and translational implications. Nat. Rev. Cancer 2011, 11:726-734.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 726-734
    • Baylin, S.B.1    Jones, P.A.2
  • 16
    • 77954842322 scopus 로고    scopus 로고
    • Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
    • Wu H., Coskun V., Tao J., Xie W., Ge W., Yoshikawa K., Li E., Zhang Y., Sun Y.E. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 2010, 329:444-448.
    • (2010) Science , vol.329 , pp. 444-448
    • Wu, H.1    Coskun, V.2    Tao, J.3    Xie, W.4    Ge, W.5    Yoshikawa, K.6    Li, E.7    Zhang, Y.8    Sun, Y.E.9
  • 17
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: the mark and its mediators
    • Klose R.J., Bird A.P. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 2006, 31:89-97.
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 22
    • 78049414227 scopus 로고    scopus 로고
    • Epigenetic reprogramming in plant and animal development
    • Feng S., Jacobsen S.E., Reik W. Epigenetic reprogramming in plant and animal development. Science 2010, 330:622-627.
    • (2010) Science , vol.330 , pp. 622-627
    • Feng, S.1    Jacobsen, S.E.2    Reik, W.3
  • 25
    • 0032534868 scopus 로고    scopus 로고
    • Characterization of gene expression, genomic structure, and chromosomal localization of Hells (Lsh)
    • Geiman T.M., Durum S.K., Muegge K. Characterization of gene expression, genomic structure, and chromosomal localization of Hells (Lsh). Genomics 1998, 54:477-483.
    • (1998) Genomics , vol.54 , pp. 477-483
    • Geiman, T.M.1    Durum, S.K.2    Muegge, K.3
  • 26
    • 0034712755 scopus 로고    scopus 로고
    • Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes
    • Geiman T.M., Muegge K. Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:4772-4777.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 4772-4777
    • Geiman, T.M.1    Muegge, K.2
  • 29
    • 2442564700 scopus 로고    scopus 로고
    • Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG
    • Sun L.Q., Lee D.W., Zhang Q., Xiao W., Raabe E.H., Meeker A., Miao D., Huso D.L., Arceci R.J. Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG. Genes Dev. 2004, 18:1035-1046.
    • (2004) Genes Dev. , vol.18 , pp. 1035-1046
    • Sun, L.Q.1    Lee, D.W.2    Zhang, Q.3    Xiao, W.4    Raabe, E.H.5    Meeker, A.6    Miao, D.7    Huso, D.L.8    Arceci, R.J.9
  • 31
    • 0032403109 scopus 로고    scopus 로고
    • Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha)
    • Reyes J.C., Barra J., Muchardt C., Camus A., Babinet C., Yaniv M. Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha). EMBO J. 1998, 17:6979-6991.
    • (1998) EMBO J. , vol.17 , pp. 6979-6991
    • Reyes, J.C.1    Barra, J.2    Muchardt, C.3    Camus, A.4    Babinet, C.5    Yaniv, M.6
  • 33
    • 0043136702 scopus 로고    scopus 로고
    • Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis
    • Fan T., Yan Q., Huang J., Austin S., Cho E., Ferris D., Muegge K. Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis. Cancer Res. 2003, 63:4677-4683.
    • (2003) Cancer Res. , vol.63 , pp. 4677-4683
    • Fan, T.1    Yan, Q.2    Huang, J.3    Austin, S.4    Cho, E.5    Ferris, D.6    Muegge, K.7
  • 35
    • 33751523649 scopus 로고    scopus 로고
    • Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells
    • De La Fuente R., Baumann C., Fan T., Schmidtmann A., Dobrinski I., Muegge K. Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells. Nat. Cell Biol. 2006, 8:1448-1454.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1448-1454
    • De La Fuente, R.1    Baumann, C.2    Fan, T.3    Schmidtmann, A.4    Dobrinski, I.5    Muegge, K.6
  • 37
    • 72849148752 scopus 로고    scopus 로고
    • Lsh participates in DNA methylation and silencing of stem cell genes
    • Xi S., Geiman T.M., Briones V., Guang Tao Y., Xu H., Muegge K. Lsh participates in DNA methylation and silencing of stem cell genes. Stem Cells 2009, 27:2691-2702.
    • (2009) Stem Cells , vol.27 , pp. 2691-2702
    • Xi, S.1    Geiman, T.M.2    Briones, V.3    Guang Tao, Y.4    Xu, H.5    Muegge, K.6
  • 39
    • 0141628697 scopus 로고    scopus 로고
    • Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin
    • Yan Q., Cho E., Lockett S., Muegge K. Association of Lsh, a regulator of DNA methylation, with pericentromeric heterochromatin is dependent on intact heterochromatin. Mol. Cell. Biol. 2003, 23:8416-8428.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8416-8428
    • Yan, Q.1    Cho, E.2    Lockett, S.3    Muegge, K.4
  • 40
    • 0141642008 scopus 로고    scopus 로고
    • Lsh, a modulator of CpG methylation, is crucial for normal histone methylation
    • Yan Q., Huang J., Fan T., Zhu H., Muegge K. Lsh, a modulator of CpG methylation, is crucial for normal histone methylation. EMBO J. 2003, 22:5154-5162.
    • (2003) EMBO J. , vol.22 , pp. 5154-5162
    • Yan, Q.1    Huang, J.2    Fan, T.3    Zhu, H.4    Muegge, K.5
  • 41
    • 0035890090 scopus 로고    scopus 로고
    • Lsh, a member of the SNF2 family, is required for genome-wide methylation
    • Dennis K., Fan T., Geiman T., Yan Q., Muegge K. Lsh, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev. 2001, 15:2940-2944.
    • (2001) Genes Dev. , vol.15 , pp. 2940-2944
    • Dennis, K.1    Fan, T.2    Geiman, T.3    Yan, Q.4    Muegge, K.5
  • 44
    • 0032907728 scopus 로고    scopus 로고
    • Maintenance of genomic methylation requires a SWI2/SNF2-like protein
    • Jeddeloh J.A., Stokes T.L., Richards E.J. Maintenance of genomic methylation requires a SWI2/SNF2-like protein. Nat. Genet. 1999, 22:94-97.
    • (1999) Nat. Genet. , vol.22 , pp. 94-97
    • Jeddeloh, J.A.1    Stokes, T.L.2    Richards, E.J.3
  • 45
    • 0037072666 scopus 로고    scopus 로고
    • Dependence of heterochromatic histone H3 methylation patterns on the Arabidopsis gene DDM1
    • Gendrel A.V., Lippman Z., Yordan C., Colot V., Martienssen R.A. Dependence of heterochromatic histone H3 methylation patterns on the Arabidopsis gene DDM1. Science 2002, 297:1871-1873.
    • (2002) Science , vol.297 , pp. 1871-1873
    • Gendrel, A.V.1    Lippman, Z.2    Yordan, C.3    Colot, V.4    Martienssen, R.A.5
  • 47
    • 34548603504 scopus 로고    scopus 로고
    • Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
    • Jia D., Jurkowska R.Z., Zhang X., Jeltsch A., Cheng X. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation. Nature 2007, 449:248-251.
    • (2007) Nature , vol.449 , pp. 248-251
    • Jia, D.1    Jurkowska, R.Z.2    Zhang, X.3    Jeltsch, A.4    Cheng, X.5
  • 49
    • 53649097070 scopus 로고    scopus 로고
    • Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
    • Arita K., Ariyoshi M., Tochio H., Nakamura Y., Shirakawa M. Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism. Nature 2008, 455:818-821.
    • (2008) Nature , vol.455 , pp. 818-821
    • Arita, K.1    Ariyoshi, M.2    Tochio, H.3    Nakamura, Y.4    Shirakawa, M.5
  • 50
    • 12844286057 scopus 로고    scopus 로고
    • Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters
    • Esteve P.O., Chin H.G., Pradhan S. Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:1000-1005.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 1000-1005
    • Esteve, P.O.1    Chin, H.G.2    Pradhan, S.3
  • 51
    • 0033919595 scopus 로고    scopus 로고
    • DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
    • Robertson K.D., Ait-Si-Ali S., Yokochi T., Wade P.A., Jones P.L., Wolffe A.P. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat. Genet. 2000, 25:338-342.
    • (2000) Nat. Genet. , vol.25 , pp. 338-342
    • Robertson, K.D.1    Ait-Si-Ali, S.2    Yokochi, T.3    Wade, P.A.4    Jones, P.L.5    Wolffe, A.P.6
  • 52
    • 0042132027 scopus 로고    scopus 로고
    • Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
    • Chen T., Ueda Y., Dodge J.E., Wang Z., Li E. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell. Biol. 2003, 23:5594-5605.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5594-5605
    • Chen, T.1    Ueda, Y.2    Dodge, J.E.3    Wang, Z.4    Li, E.5
  • 55
    • 70449723345 scopus 로고    scopus 로고
    • Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF
    • Bouazoune K., Miranda T.B., Jones P.A., Kingston R.E. Analysis of individual remodeled nucleosomes reveals decreased histone-DNA contacts created by hSWI/SNF. Nucleic Acids Res. 2009, 37:5279-5294.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 5279-5294
    • Bouazoune, K.1    Miranda, T.B.2    Jones, P.A.3    Kingston, R.E.4
  • 56
    • 0037428383 scopus 로고    scopus 로고
    • Deficient in DNA methylation 1 (DDM1) defines a novel family of chromatin-remodeling factors
    • Brzeski J., Jerzmanowski A. Deficient in DNA methylation 1 (DDM1) defines a novel family of chromatin-remodeling factors. J. Biol. Chem. 2003, 278:823-828.
    • (2003) J. Biol. Chem. , vol.278 , pp. 823-828
    • Brzeski, J.1    Jerzmanowski, A.2
  • 57
    • 37549061829 scopus 로고    scopus 로고
    • LSH cooperates with DNA methyltransferases to repress transcription
    • Myant K., Stancheva I. LSH cooperates with DNA methyltransferases to repress transcription. Mol. Cell. Biol. 2008, 28:215-226.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 215-226
    • Myant, K.1    Stancheva, I.2
  • 60
    • 0038813684 scopus 로고    scopus 로고
    • Genomics. Not junk after all
    • Makalowski W. Genomics. Not junk after all. Science 2003, 300:1246-1247.
    • (2003) Science , vol.300 , pp. 1246-1247
    • Makalowski, W.1
  • 65
    • 77949374305 scopus 로고    scopus 로고
    • Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation
    • Tao Y., Xi S., Briones V., Muegge K. Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation. PLoS One 2010, 5:e9163.
    • (2010) PLoS One , vol.5
    • Tao, Y.1    Xi, S.2    Briones, V.3    Muegge, K.4
  • 66
    • 34547747862 scopus 로고    scopus 로고
    • Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1
    • Saze H., Kakutani T. Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1. EMBO J. 2007, 26:3641-3652.
    • (2007) EMBO J. , vol.26 , pp. 3641-3652
    • Saze, H.1    Kakutani, T.2
  • 68
    • 83755185498 scopus 로고    scopus 로고
    • Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS
    • Tao Y., Liu S., Briones V., Geiman T.M., Muegge K. Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS. Nucleic Acids Res. 2011, 39:9508-9520.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 9508-9520
    • Tao, Y.1    Liu, S.2    Briones, V.3    Geiman, T.M.4    Muegge, K.5
  • 69
    • 65049091772 scopus 로고    scopus 로고
    • Regulation of Hox gene activity by transcriptional elongation in Drosophila
    • Chopra V.S., Hong J.W., Levine M. Regulation of Hox gene activity by transcriptional elongation in Drosophila. Curr. Biol. 2009, 19:688-693.
    • (2009) Curr. Biol. , vol.19 , pp. 688-693
    • Chopra, V.S.1    Hong, J.W.2    Levine, M.3


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