메뉴 건너뛰기




Volumn 3, Issue , 2012, Pages

Biomarkers of therapeutic response in the IL-23 pathway in inflammatory bowel disease

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CALGRANULIN A; CALGRANULIN B; CELL PROTEIN; DELETED IN MALIGNANT TUMOR 1 PROTEIN; IMMUNOGLOBULIN G1 ANTIBODY; INTERLEUKIN 23 ANTIBODY; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 23 RECEPTOR MONOCLONAL ANTIBODY; INTERLEUKIN 23P19 MONOCLONAL ANTIBODY; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; MONOCLONAL ANTIBODY; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PANCREATITIS ASSOCIATED PROTEIN; REGENERATING PROTEIN 3BETA; REGENERATING PROTEIN 3GAMMA; UNCLASSIFIED DRUG;

EID: 84861872216     PISSN: None     EISSN: 2155384X     Source Type: Journal    
DOI: 10.1038/ctg.2012.2     Document Type: Article
Times cited : (50)

References (46)
  • 1
    • 43549099743 scopus 로고    scopus 로고
    • The Interleukin-23/Interleukin-17 axis in intestinal inflammation
    • DOI 10.1111/j.1365-2796.2008.01950.x
    • Maloy KJ. The interleukin-23/interleukin-17 axis in intestinal inflammation. J Intern Med 2008; 263: 584-590. (Pubitemid 351678587)
    • (2008) Journal of Internal Medicine , vol.263 , Issue.6 , pp. 584-590
    • Maloy, K.J.1
  • 2
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13: 715-725.
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3
  • 4
    • 33646397611 scopus 로고    scopus 로고
    • IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
    • Yen D, Cheung J, Scheerens H et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 2006; 116: 1310-1316.
    • (2006) J Clin Invest , vol.116 , pp. 1310-1316
    • Yen, D.1    Cheung, J.2    Scheerens, H.3
  • 5
    • 33646433989 scopus 로고    scopus 로고
    • Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
    • Chen Y, Langrish CL, McKenzie B et al. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J Clin Invest 2006; 116: 1317-1326.
    • (2006) J Clin Invest , vol.116 , pp. 1317-1326
    • Chen, Y.1    Langrish, C.L.2    McKenzie, B.3
  • 8
    • 33747089041 scopus 로고    scopus 로고
    • Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
    • Uhlig HH, McKenzie BS, Hue S et al. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity 2006; 25: 309-318.
    • (2006) Immunity , vol.25 , pp. 309-318
    • Uhlig, H.H.1    McKenzie, B.S.2    Hue, S.3
  • 9
    • 13944281011 scopus 로고    scopus 로고
    • Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis
    • DOI 10.1097/00054725-200501000-00003
    • Schmidt C, Giese T, Ludwig B et al. Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis. Inflamm Bowel Dis 2005; 11: 16-23. (Pubitemid 40340252)
    • (2005) Inflammatory Bowel Diseases , vol.11 , Issue.1 , pp. 16-23
    • Schmidt, C.1    Giese, T.2    Ludwig, B.3    Mueller-Molaian, I.4    Marth, T.5    Zeuzem, S.6    Meuer, S.C.7    Stallmach, A.8
  • 10
    • 56549104968 scopus 로고    scopus 로고
    • IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
    • Kobayashi T, Okamoto S, Hisamatsu T et al. IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease. Gut 2008; 57: 1682-1689.
    • (2008) Gut , vol.57 , pp. 1682-1689
    • Kobayashi, T.1    Okamoto, S.2    Hisamatsu, T.3
  • 12
    • 80053991071 scopus 로고    scopus 로고
    • Functional Studies on the IBD Susceptibility Gene IL23R implicate reduced receptor function in the protective genetic variant R381Q
    • Pidasheva S, Trifari S, Phillips A et al. Functional Studies on the IBD Susceptibility Gene IL23R implicate reduced receptor function in the protective genetic variant R381Q. PLoS One 2011; 6: e25038.
    • (2011) PLoS One , vol.6
    • Pidasheva, S.1    Trifari, S.2    Phillips, A.3
  • 13
    • 33646695671 scopus 로고    scopus 로고
    • Rationale and safety of anti-interleukin-23 and anti-interleukin-17A therapy
    • DOI 10.1191/0309133306pp482pr, PII 0000143220060600000005
    • Bowman EP, Chackerian AA, Cua DJ. Rationale and safety of anti-interleukin-23 and antiinterleukin-17A therapy. Curr Opin Infect Dis 2006; 19: 245-252. (Pubitemid 43740362)
    • (2006) Current Opinion in Infectious Diseases , vol.19 , Issue.3 , pp. 245-252
    • Bowman, E.P.1    Chackerian, A.A.2    Cua, D.J.3
  • 14
    • 38349090575 scopus 로고    scopus 로고
    • The state of innovation in drug development
    • Kola I. The state of innovation in drug development. Clin Pharmacol Ther 2008; 83: 227-230.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 227-230
    • Kola, I.1
  • 15
    • 0030273141 scopus 로고    scopus 로고
    • The SCID but not the RAG-2 gene product is required for Smu-S epsilon heavy chain class switching
    • DOI 10.1016/S1074-7613(00)80258-7
    • Rolink A, Melchers F, Andersson J. The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching. Immunity 1996; 5: 319-330. (Pubitemid 26366755)
    • (1996) Immunity , vol.5 , Issue.4 , pp. 319-330
    • Rolink, A.1    Melchers, F.2    Andersson, J.3
  • 16
    • 0034663766 scopus 로고    scopus 로고
    • + T cells requires CD40-CD40 ligand interactions for a sustained increase in mucosal IL-12
    • Cong Y, Weaver CT, Lazenby A, Elson CO. Colitis induced by enteric bacterial antigenspecific CD4+ T cells requires CD40-CD40 ligand interactions for a sustained increase in mucosal IL-12. J Immunol 2000; 165: 2173-2182. (Pubitemid 30643167)
    • (2000) Journal of Immunology , vol.165 , Issue.4 , pp. 2173-2182
    • Cong, Y.1    Weaver, C.T.2    Lazenby, A.3    Elson, C.O.4
  • 18
    • 26844499100 scopus 로고    scopus 로고
    • Comparative plasma proteome analysis of lymphoma-bearing SJL mice
    • Bhat VB, Choi MH, Wishnok JS, Tannenbaum SR. Comparative plasma proteome analysis of lymphoma-bearing SJL mice. J Proteome Res 2005; 4: 1814-1825.
    • (2005) J Proteome Res , vol.4 , pp. 1814-1825
    • Bhat, V.B.1    Choi, M.H.2    Wishnok, J.S.3    Tannenbaum, S.R.4
  • 19
    • 33947683926 scopus 로고    scopus 로고
    • Diagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy
    • von Roon AC, Karamountzos L, Purkayastha S et al. Diagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy. Am J Gastroenterol 2007; 102: 803-813.
    • (2007) Am J Gastroenterol , vol.102 , pp. 803-813
    • Von Roon, A.C.1    Karamountzos, L.2    Purkayastha, S.3
  • 20
    • 50149097975 scopus 로고    scopus 로고
    • IL-22 in mucosal immunity
    • Ouyang W, Valdez P. IL-22 in mucosal immunity. Mucosal Immunol 2008; 1: 335-338.
    • (2008) Mucosal Immunol , vol.1 , pp. 335-338
    • Ouyang, W.1    Valdez, P.2
  • 21
    • 0030981088 scopus 로고    scopus 로고
    • Tumour necrosis factor and Crohn's disease
    • Van Deventer SJ. Tumour necrosis factor and Crohn's disease. Gut 1997; 40: 443-448. (Pubitemid 27204920)
    • (1997) Gut , vol.40 , Issue.4 , pp. 443-448
    • Van Deventer, S.J.H.1
  • 22
    • 40049111515 scopus 로고    scopus 로고
    • Treatment of inflammatory bowel disease: A review of medical therapy
    • DOI 10.3748/wjg.14.354
    • Kozuch PL, Hanauer SB. Treatment of inflammatory bowel disease: a review of medical therapy. World J Gastroenterol 2008; 14: 354-377. (Pubitemid 351320845)
    • (2008) World Journal of Gastroenterology , vol.14 , Issue.3 , pp. 354-377
    • Kozuch, P.L.1    Hanauer, S.B.2
  • 23
    • 0036895299 scopus 로고    scopus 로고
    • Colonic epithelial cells are a major site of macrophage inflammatory protein 3alpha (MIP-3alpha) production in normal colon and inflammatory bowel disease
    • DOI 10.1136/gut.51.6.818
    • Kwon JH, Keates S, Bassani L et al. Colonic epithelial cells are a major site of macrophage inflammatory protein 3alpha (MIP-3alpha) production in normal colon and inflammatory bowel disease. Gut 2002; 51: 818-826. (Pubitemid 35408603)
    • (2002) Gut , vol.51 , Issue.6 , pp. 818-826
    • Kwon, J.H.1    Keates, S.2    Bassani, L.3    Mayer, L.F.4    Keates, A.C.5
  • 25
    • 68849124464 scopus 로고    scopus 로고
    • The role of the novel Th17 cytokine IL-26 in intestinal inflammation
    • Dambacher J, Beigel F, Zitzmann K et al. The role of the novel Th17 cytokine IL-26 in intestinal inflammation. Gut 2009; 58: 1207-1217.
    • (2009) Gut , vol.58 , pp. 1207-1217
    • Dambacher, J.1    Beigel, F.2    Zitzmann, K.3
  • 26
    • 84861913672 scopus 로고    scopus 로고
    • Serum and mucosal S100 proteins, calprotectin (S100A8/S100A9) and S100A12, are elevated at diagnosis in children with inflammatory bowel disease
    • Leach ST, Yang Z, Messina I et al. Serum and mucosal S100 proteins, calprotectin (S100A8/S100A9) and S100A12, are elevated at diagnosis in children with inflammatory bowel disease. Scand J Gastroenterol 21; 2007: 1-11.
    • (2007) Scand J Gastroenterol , vol.21 , pp. 1-11
    • Leach, S.T.1    Yang, Z.2    Messina, I.3
  • 31
    • 33645829078 scopus 로고    scopus 로고
    • IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
    • Brand S, Beigel F, Olszak T et al. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am J Physiol Gastrointest Liver Physiol 2006; 290: G827-G838.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Brand, S.1    Beigel, F.2    Olszak, T.3
  • 32
    • 39649121919 scopus 로고    scopus 로고
    • Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status
    • DOI 10.1002/ibd.20315
    • Schmechel S, Konrad A, Diegelmann J et al. Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status. Inflamm Bowel Dis 2008; 14: 204-212. (Pubitemid 351288041)
    • (2008) Inflammatory Bowel Diseases , vol.14 , Issue.2 , pp. 204-212
    • Schmechel, S.1    Konrad, A.2    Diegelmann, J.3    Glas, J.4    Wetzke, M.5    Paschos, E.6    Lohse, P.7    Goke, B.8    Brand, S.9
  • 33
    • 54349088988 scopus 로고    scopus 로고
    • IL-23/IL-17 immunity as a hallmark of Crohn's disease
    • Holtta V, Klemetti P, Sipponen T et al. IL-23/IL-17 immunity as a hallmark of Crohn's disease. Inflamm Bowel Dis 2008; 14: 1175-1184.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1175-1184
    • Holtta, V.1    Klemetti, P.2    Sipponen, T.3
  • 34
    • 33845868493 scopus 로고    scopus 로고
    • S100 proteins expressed in phagocytes: A novel group of damage-associated molecular pattern molecules
    • DOI 10.1189/jlb.0306170
    • Foell D, Wittkowski H, Vogl T, Roth J. S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules. J Leukoc Biol 2007; 81: 28-37. (Pubitemid 46021248)
    • (2007) Journal of Leukocyte Biology , vol.81 , Issue.1 , pp. 28-37
    • Foell, D.1    Wittkowski, H.2    Vogl, T.3    Roth, J.4
  • 38
    • 67650474246 scopus 로고    scopus 로고
    • STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
    • Pickert G, Neufert C, Leppkes M et al. STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing. J Exp Med 2009; 206: 1465-1472.
    • (2009) J Exp Med , vol.206 , pp. 1465-1472
    • Pickert, G.1    Neufert, C.2    Leppkes, M.3
  • 39
    • 48349136889 scopus 로고    scopus 로고
    • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    • Barrett JC, Hansoul S, Nicolae DL et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008; 40: 955-962.
    • (2008) Nat Genet , vol.40 , pp. 955-962
    • Barrett, J.C.1    Hansoul, S.2    Nicolae, D.L.3
  • 42
    • 50249185512 scopus 로고    scopus 로고
    • Inflammation, adenoma and cancer: Objective classification of colon biopsy specimens with gene expression signature
    • Galamb O, Gyorffy B, Sipos F et al. Inflammation, adenoma and cancer: objective classification of colon biopsy specimens with gene expression signature. Dis Markers 2008; 25: 1-16.
    • (2008) Dis Markers , vol.25 , pp. 1-16
    • Galamb, O.1    Gyorffy, B.2    Sipos, F.3
  • 45
    • 0030924448 scopus 로고    scopus 로고
    • Role of macrophage migration inhibitory factor in the regulation of the immune response
    • Metz CN, Bucala R. Role of macrophage migration inhibitory factor in the regulation of the immune response. Adv Immunol 1997; 66: 197-223. (Pubitemid 127702123)
    • (1997) Advances in Immunology , vol.66 , pp. 197-223
    • Metz, C.N.1    Bucala, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.