Metabolite profiling and pharmacokinetics of herbal compounds following oral administration of a cardiovascular multi-herb medicine (Qishen Yiqi Pills) in rat

Current Drug Metabolism

Volumn 13, Issue 5, 2012, Pages 510-523

  Zhang, Yufeng ^a   Shi, Peiying ^a   Yao, Hong ^a   Shao, Qing ^a   Fan, Xiaohui ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Chinese herbal medicine; Metabolism; Pharmacokinetics; Qishen yiqi pills

Indexed keywords

3 METHOXYL 3 SULFOOXY HIPPURIC ACID; 4 METHOXYL 3 SULFOOXY HIPPURIC ACID; 4' DEMETHYL CALYCOSIN 7 O BETA DEXTRO GLUCURONIDE; 8 HYDROXYL CALYCOSIN SULFATE; ASTRAGALOSIDE IV; CALYCOSIN 3' O BETA DEXTRO GLUCURONIDE; CALYCOSIN 7 O BETA DEXTRO GLUCURONIDE 3' SULFATE; CARDIOVASCULAR AGENT; CHINESE DRUG; DRUG METABOLITE; E NEROLIDOL; FORMONONETIN 7 SULFATE; GINSENOSIDE RB 1; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RG 1; HERBACEOUS AGENT; ISOFERULIC ACID 4 O SULFATE; ISOVANILLIC ACID 3' GLUCURONIDE; ISOVANILLIN GLUCURONIDE; PROTOCATECHUIC ACID SULFATE; QISHEN YIQI PILL; ROSMARINIC ACID; SALVIANOLIC ACID D; SALVIANOLIC ACID H; TANSHINOL; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANILLIC ACID 4' GLUCURONIDE; VANILLIN GLUCURONIDE; VANILLIN SULFATE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; ASTRAGALUS MEMBRANACEUS; BILE; BLOOD ANALYSIS; DALBERGIA; DALBERGIA ODORIFERA; DRUG CONCENTRATION; DRUG DETERMINATION; DRUG EXPOSURE; DRUG MEGADOSE; DRUG METABOLISM; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MALE; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PANAX NOTOGINSENG; RAT; SALVIA MILTIORRHIZA; TIME OF FLIGHT MASS SPECTROMETRY; URINALYSIS;

EID: 84861866755     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/1389200211209050510     Document Type: Article

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