Influence of segmental and selected ion monitoring on quantitation of multi-component using high-pressure liquid chromatography-quadrupole mass spectrometry: Simultaneous detection of 16 saponins in rat plasma as a case

Journal of Chromatography A

Volumn 1217, Issue 26, 2010, Pages 4501-4506

  Liang, Yan ^a   Kang, An ^a   Xie, Tong ^a   Zheng, Xiao ^a   Dai, Chen ^a   Hao, Haiping ^a   A, Jiye ^a   Sheng, Longsheng ^a   Xie, Lin ^a   Wang, Guang Ji ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

LC Q MS; Saponins; Segmental and selected ion monitoring

Indexed keywords

ANALYTES; ANALYTICAL TOOL; CHINESE HERBAL MEDICINES; DYNAMIC RANGE; ENVIRONMENTAL MONITORING; HIGH-PRESSURE LIQUID; LOW COSTS; LOWER LIMITS; METABONOMICS; MULTI-COMPONENT ANALYSIS; MULTICOMPONENTS; QUADRUPOLE MASS SPECTROMETRY; QUADRUPOLES; QUANTITATIVE ANALYSIS; RAT PLASMA; SELECTED ION MONITORING; SIMULTANEOUS DETECTION; UPPER LIMITS;

HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONS; MASS SPECTROMETRY; MEDICINE; METABOLITES;

CHEMICAL ANALYSIS;

DIGOXIN; GINSENOSIDE F 1; GINSENOSIDE F 2; GINSENOSIDE NOTO R1; GINSENOSIDE RB 1; GINSENOSIDE RB 2; GINSENOSIDE RC; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RF; GINSENOSIDE RG 1; GINSENOSIDE RG 2; GINSENOSIDE RG 3; GINSENOSIDE RH 1; GINSENOSIDE RH 2; GINSENOSIDE RT 5; OPHIOPOGON D; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STRUCTURE; ENVIRONMENTAL MONITORING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION MONITORING; NONHUMAN; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY ANALYSIS; SIGNAL NOISE RATIO; VALIDATION PROCESS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MASS SPECTROMETRY; RATS; SAPONINS;

RATTUS;

EID: 77953503364     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2010.04.054     Document Type: Article

References (14)

1. Joo K.M., Lee J.H., Jeon H.Y., Park C.W., Hong D.K., Jeong H.J., Lee S.J., Lee S.Y., Lim K.M. J. Pharm. Biomed. Anal. 2010, 51:278.
2. Xia C.H., Sun J.G., Wang G.J., Shang L.L., Zhang X.X., Zhang R., Wang X.J., Hao H.P., Xie L. Chem. Biol. Interact. 2009, 180:440.
3. Vincken J.P., Heng L., de Groot A., Gruppen H. Phytochemistry 2007, 68:275.
4. Sparg S.G., Light M.E., Stadenvan J. J. Ethnopharmacol. 2004, 94:219.
5. Melek F.R., Toshio M., Abdel-Khalik S.M., Hetta M.H., Mahmoud I.I. Phytochemistry 2002, 60:185.
6. Lars P.C. Adv. Food Nutr. Res. 2009, 5:1.
7. Gui F.J., Yang X.W., Li L.Y., Tian J.M. J. Chromatogr. B 2007, 850:1.
8. Wang W., Wang G., Xie H., Sun J., Zhao S., Jiang X., Li H., Lv H., Xu M., Wang R. J. Chromatogr. B 2007, 852:8.
9. Gu Y., Wang G.J., Sun J.G., Jia Y.W., Wang W., Xu M.J., Lv T., Zheng Y.T., Sai Y. Food Chem. Toxicol. 2009, 47:2257.
10. Ji H.Y., Lee H.W. J. Pharm. Biomed. Anal. 2004, 35:207.
11. Xia C.H., Wang G.J., Sun J.G., Hao H.P., Xiong Y.Q., Gu S.H., Shang L.L., Zheng C.N. J. Chromatogr. B 2008, 862:72.
12. Herron W.J., Eadie J., Penman A.D. J. Chromatogr. A 1995, 712:55.
13. Li X., Wang G., Sun J., Hao H., Xiong Y., Yan B., Zheng Y., Sheng L. Biol. Pharm. Bull. 2007, 30:847.
14. Xu Q.F., Fang X.L., Chen D.F. Ethnopharmacology 2003, 84:187.