Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux

Lipids in Health and Disease

Volumn 11, Issue , 2012, Pages

  Jiang, Hong ^a   Badralmaa, Yunden ^a   Yang, Jun ^a   Lempicki, Richard ^a   Hazen, Allison ^a   Natarajan, Ven ^a  

^a SAIC FREDERICK INC   (United States)

Author keywords

ABCA1; ATRA; CD4+ T cells; cholesterol efflux; HIV 1; LXR; RAR; retinoic acid; RXR; TO 901317

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; RETINOIC ACID; T LYMPHOCYTE RECEPTOR;

ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG POTENTIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THERAPY EFFECT; UPREGULATION;

ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CD4-POSITIVE T-LYMPHOCYTES; CHOLESTEROL; DRUG SYNERGISM; HIV INFECTIONS; HIV-1; HUMANS; HYDROCARBONS, FLUORINATED; JURKAT CELLS; LIGANDS; ORPHAN NUCLEAR RECEPTORS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SULFONAMIDES; TRETINOIN; UP-REGULATION; VIRUS INTERNALIZATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84861857191     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-11-69     Document Type: Article

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