Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1

Molecular Pharmacology

Volumn 78, Issue 2, 2010, Pages 215-225

  Morrow, Matthew P ^a   Grant, Angela ^a   Mujawar, Zahedi ^a   Dubrovsky, Larisa ^a   Pushkarsky, Tatiana ^a   Kiselyeva, Yana ^b   Jennelle, Lucas ^a   Mukhamedova, Nigora ^c   Remaley, Alan T ^d   Kashanchi, Fatah ^a   Sviridov, Dmitri ^c   Bukrinsky, Michael ^a  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^d NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CHOLESTEROL; LIGAND; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL TYPE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; EX VIVO STUDY; EXPERIMENTAL INFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VIVO STUDY; LYMPHOID TISSUE; MACROPHAGE; NONHUMAN; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RNA INTERFERENCE; T LYMPHOCYTE; TANGIER DISEASE; TISSUE CULTURE; VIRION; VIRUS INFECTIVITY; VIRUS INHIBITION; VIRUS REPLICATION;

ANIMALS; ANIMALS, NEWBORN; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CHOLESTEROL; HIV-1; HUMANS; HYDROCARBONS, FLUORINATED; MICE; ORPHAN NUCLEAR RECEPTORS; RNA INTERFERENCE; SULFONAMIDES; VIRUS REPLICATION;

EID: 77954944601     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.065029     Document Type: Article

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