Effect of fruit and vegetable intake on oxidative stress and inflammation in COPD: A randomised controlled trial

European Respiratory Journal

Volumn 39, Issue 6, 2012, Pages 1377-1384

  Baldrick, Francina R ^a   Elborn, J Stuart ^a,b   Woodside, Jayne V ^a   Treacy, Katherine ^b   Bradley, Judy M ^b,c   Patterson, Chris C ^a   Schock, Bettina C ^a   Ennis, Madeleine ^a   Young, Ian S ^a   McKinley, Michelle C ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b BELFAST CITY HOSPITAL   (United Kingdom)

^c UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

Chronic obstructive pulmonary disease; Fruit; Inflammation; Oxidative stress; Vegetables

Indexed keywords

8 ISOPROSTANE; ALPHA CAROTENE; ASCORBIC ACID; BETA CAROTENE; BETA CRYPTOXANTHIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERLEUKIN 8; LYCOPENE; MYELOPEROXIDASE; XANTHOPHYLL; ZEAXANTHIN;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DIETARY INTAKE; DISEASE SEVERITY; EXPLORATORY RESEARCH; FEMALE; FRUIT; HUMAN; MAJOR CLINICAL STUDY; MALE; OPEN STUDY; OXIDATIVE STRESS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFLAMMATION; SELF REPORT; VEGETABLE;

AGED; AGED, 80 AND OVER; ANTICARCINOGENIC AGENTS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; DIET; DINOPROST; FEMALE; FOOD HABITS; FRUIT; HUMANS; INFLAMMATION; INTERLEUKIN-8; MALE; MIDDLE AGED; OXIDATIVE STRESS; PATIENT COMPLIANCE; PEROXIDASE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SEVERITY OF ILLNESS INDEX; SPUTUM; VEGETABLES; XANTHOPHYLLS;

EID: 84861843704     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00086011     Document Type: Article

References (36)

1. Lopez AD, Murray CC. The global burden of disease, 1990-2020. Nat Med 1998; 4: 1241-1243.
2. Smit HA, Grievink L, Tabak C. Dietary influences on chronic obstructive lung disease and asthma: a review of the epidemiological evidence. Proc Nutr Soc 1999; 58: 309-319.
3. Romieu I, Trenga C. Diet and obstructive lung diseases. Epidemiol Rev 2001; 23: 268-287.
4. Tabak C, Smit HA, Heederik D, et al. Diet and chronic obstructive pulmonary disease: independent beneficial effects of fruits, whole grains, and alcohol (the MORGEN study). Clin Exp Allergy 2001; 31: 747-755.
5. Kelly Y, Sacker A, Marmot M. Nutrition and respiratory health in adults: findings from the Health Survey for Scotland. Eur Respir J 2003; 21: 664-671.
6. Carey IM, Strachan DP, Cook DG. Effects of changes in fresh fruit consumption on ventilatory function in healthy British adults. Am J Respir Crit Care Med 1998; 158: 728-733.
7. Walda IC, Tabak C, Smit HA, et al. Diet and 20-year chronic obstructive pulmonary disease mortality in middle-aged men from three European countries. Eur J Clin Nutr 2002; 56: 638-643.
8. Tsiligianni IG, van der Molen T. A systematic review of the role of vitamin insufficiencies and supplementation in COPD. Respir Res 2010; 11: 171.
9. Cerdá B, Soto C, Albaladejo MD, et al. Pomegranate juice supplementation in chronic obstructive pulmonary disease: a 5-week randomized, double-blind, placebo-controlled trial. Eur J Clin Nutr 2006; 60: 245-253.
10. Keranis E, Makris D, Rodopoulou P, et al. Impact of dietary shift to higher-antioxidant foods in COPD: a randomised trial. Eur Respir J 2010; 36: 774-780.
11. Baldrick FR, Woodside JV, Elborn JS, et al. Biomarkers of fruit and vegetable intake in human intervention studies: a systematic review. Crit Rev Food Sci Nutr 2011; 51: 795-815.
12. Watzl B, Kulling SE, Moseneder J, et al. A 4-wk intervention with high intake of carotenoid-rich vegetables and fruit reduces plasma C-reactive protein in healthy, nonsmoking men. Am J Clin Nutr 2005; 82: 1052-1058.
13. 2αexcretion is reduced in women by increased vegetable and fruit intake. Am J Clin Nutr 2005; 82: 768-776.
14. Sofi F, Ghiselli L, Cesari F, et al. Effects of short-term consumption of bread obtained by an old Italian grain variety on lipid, inflammatory, and hemorheological variables: an intervention study. J Med Food 2010; 13: 615-620.
15. Sofi F, Buccioni A, Cesari F, et al. Effects of a dairy product (pecorino cheese) naturally rich in cis-9, trans-11 conjugated linoleic acid on lipid, inflammatory and haemorheological variables: a dietary intervention study. Nutr Metab Cardiovasc Dis 2010; 20: 117-124.
16. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J 2005; 26: 319-338.
17. Knudson RJ, Lebowitz MD, Holberg CJ, et al. Changes in the normal maximal expiratory flow-volume curve with growth and aging. Am Rev Respir Dis 1983; 127: 725-734.
18. Kelly MG, Brown V, Martin SL, et al. Comparison of sputum induction using high-output and low-output ultrasonic nebulizers in normal subjects and patients with COPD. Chest 2002; 122: 955-959.
19. Vuilleumier JP, Keck E. Fluorometric assay of vitamin C in biological materials using a centrifugal analyser with fluorescence attachment. J Micronutr Anal 1989; 5: 25-34.
20. Craft NE. Carotenoid reversed-phase high-performance liquid chromatography methods: reference compendium. Methods Enzymol 1992; 213: 185-205.
21. Martin SL, Moffitt KL, McDowell A, et al. Association of airway cathepsin B and S with inflammation in cystic fibrosis. Pediatr Pulmonol 2010; 45: 860-868.
22. Bailey DM, Williams C, Betts JA, et al. Oxidative stress, inflammation and recovery of muscle function after damaging exercise: effect of 6-week mixed antioxidant supplementation. Eur J Appl Physiol 2011; 111: 925-936.
23. Wedzicha JA, Seemungal TA. COPD exacerbations: defining their cause and prevention. Lancet 2007; 370: 786-796.
24. Pauwels R, Calverley P, Buist AS, et al. COPD exacerbations: the importance of a standard definition. Respir Med 2002; 98: 99-107.
25. Gey KF. Vitamins E plus C and interacting conutrients required for optimal health. A critical and constructive review of epidemiology and supplementation data regarding cardiovascular disease and cancer. Biofactors 1998; 7: 113-174.
26. McCall DO, McGartland CP, McKinley MC, et al. Dietary intake of fruits and vegetables improves microvascular function in hypertensive subjects in a dose-dependent manner. Circulation 2009; 119: 2153-2160.
27. Cazzola M, MacNee W, Martinez FJ, et al. Outcomes for COPD pharmacological trials: from lung function to biomarkers. Eur Respir J 2008; 31: 416-468.
28. Stockley RA. Progression of chronic obstructive pulmonary disease: impact of inflammation, comorbidities and therapeutic intervention. Curr Med Res Opin 2009; 25: 1235-1245.
29. Gan WQ, Man SF, Senthilselvan A, et al. Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis. Thorax 2004; 59: 574-580.
30. Louhelainen N, Myllarniemi M, Rahman I, et al. Airway biomarkers of the oxidant burden in asthma and chronic obstructive pulmonary disease: current and future perspectives. Int J Chron Obstruct Pulmon Dis 2008; 3: 585-603.
31. McCall DO, McGartland CP, McKinley MC, et al. The effect of increased dietary fruit and vegetable consumption on endothelial activation, inflammation and oxidative stress in hypertensive volunteers. Nutr Metab Cardiovasc Dis 2011; 21: 658-664.
32. Esposito K, Marfella R, CiotolaM, et al. Effect of aMediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome. JAMA 2004; 292: 1440-1446.
33. Rallidis LS, Lekakis J, Kolomvotsou A, et al. Close adherence to a Mediterranean diet improves endothelial function in subjects with abdominal obesity. Am J Clin Nutr 2009; 90: 263-268.
34. Barnes PJ, Chowdhury B, Kharitonov SA, et al. Pulmonary biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006; 174: 6-14.
35. Kelly FJ. Vitamins and respiratory disease: antioxidant micronutrients in pulmonary health and disease. Proc Nutr Soc 2005; 64: 510-526.
36. Schock BC, Young IS, Brown V, et al. Antioxidants and protein carbonyls in bronchoalveolar lavage fluid of children: normal data. Pediatr Res 2001; 49: 155-161.