Oxidative stress, inflammation and recovery of muscle function after damaging exercise: Effect of 6-week mixed antioxidant supplementation

European Journal of Applied Physiology

Volumn 111, Issue 6, 2011, Pages 925-936

  Bailey, David M ^a   Williams, Clyde ^a   Betts, James A ^b   Thompson, Dylan ^b   Hurst, Tina L ^c  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BATH   (United Kingdom)

^c UNILEVER RESEARCH   (United Kingdom)

Author keywords

Ascorbic acid; Cytokines; Muscle damage; RRR tocopherol

Indexed keywords

ANTIOXIDANT; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG COMBINATION; DRUG EFFECT; EXERCISE; HUMAN; INFLAMMATION; MALE; MUSCLE DISEASE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SKELETAL MUSCLE;

ADULT; ANTIOXIDANTS; CROSS-OVER STUDIES; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; EXERCISE; HUMANS; INFLAMMATION; MALE; MUSCLE, SKELETAL; MUSCULAR DISEASES; OXIDATIVE STRESS; PHYSICAL EXERTION; PLACEBOS; RECOVERY OF FUNCTION; YOUNG ADULT;

EID: 79958175116     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-010-1718-x     Document Type: Article

References (62)

1. HM Alessio AH Goldfarb G Cao 1997 Exercise-induced oxidative stress before and after vitamin C supplementation Int J Sport Nutr 7 1 9 9063760 1:CAS:528:DyaK2sXitVeis7o%3D
2. G Atkinson 2002 Analysis of repeated measurements in physical therapy research: multiple comparisons amongst level means and multifactorial designs Phys Ther Sport 3 191 203 10.1054/ptsp.2002.0123 (Pubitemid 35469965)
3. JA Betts RJ Toone KA Stokes D Thompson 2009 Systemic indices of skeletal muscle damage and recovery of muscle function after exercise: effect of combined carbohydrate-protein ingestion Appl Physiol Nutr Metab 34 773 784 19767814 10.1139/H09-070 1:CAS:528:DC%2BD1MXhtVSjsrrP
4. RJ Bloomer AH Goldfarb MJ McKenzie 2006 Oxidative stress response to aerobic exercise: comparison of antioxidant supplements Med Sci Sports Exerc 38 1098 1105 16775552 10.1249/01.mss.0000222839.51144.3e 1:CAS:528: DC%2BD28XlsFOmtbw%3D (Pubitemid 43902493)
5. RJ Bloomer MJ Falvo BK Schilling WA Smith 2007 Prior exercise and antioxidant supplementation: effect on oxidative stress and muscle injury J Int Soc Sports Nutr 4 9 17915021 10.1186/1550-2783-4-9 (Pubitemid 351819247)
6. G Borg 1973 Perceived exertion: a note on "history" and methods Med Sci Sports 5 90 93 4721012 1:STN:280:DyaE3s3isFKltw%3D%3D
7. R Brigelius-Flohe 2009 Commentary: oxidative stress reconsidered Genes Nutr 4 161 163 19609586 10.1007/s12263-009-0131-8 1:CAS:528:DC%2BD1MXhtlGgtLrK
8. SJ Brown RB Child AE Donnelly JM Saxton SH Day 1996 Changes in human muscle contractile function following stimulated eccentric exercise Eur J Appl Physiol 72 515 521 10.1007/BF00242284 1:STN:280:DyaK283ltlCktg%3D%3D (Pubitemid 26081023)
9. SK Calderwood SS Mambula PJ Gray Jr JR Theriault 2007 Extracellular heat shock proteins in cell signaling FEBS Lett 581 3689 3694 17499247 10.1016/j.febslet.2007.04.044 1:CAS:528:DC%2BD2sXotlaisLs%3D (Pubitemid 47081004)
10. JG Cannon SF Orencole RA Fielding M Meydani SN Meydani MA Fiatarone JB Blumberg WJ Evans 1990 Acute response in exercise: interaction of age and vitamin E on neutrophils and muscle enzyme release Am J Physiol 259 R1214 R1219 2175569 1:CAS:528:DyaK3MXnvFWrsA%3D%3D
11. JG Cannon SN Meydani RA Fielding MA Fiatarone M Meydani M Farhangmehr SF Orencole JB Blumberg WJ Evans 1991 Acute phase response in exercise II. Associations between vitamin E, cytokines, and muscle proteolysis Am J Physiol 260 R1235 R1240 1905495 1:CAS:528:DyaK3MXks12ktrk%3D
12. A Carr B Frei 1999 Does vitamin C act as a pro-oxidant under physiological conditions? FASEB J 13 1007 1024 10336883 1:CAS:528: DyaK1MXjsVOlurg%3D (Pubitemid 29249726)
13. PM Clarkson MJ Hubal 2002 Exercise-induced muscle damage in humans Am J Phys Med Rehabil 81 S52 S69 12409811 10.1097/00002060-200211001-00007 (Pubitemid 35192966)
14. DL Costill DD Pascoe WJ Fink RA Robergs SI Barr DR Pearson 1990 Impaired muscle glycogen resynthesis after eccentric exercise J Appl Physiol 69 46 50 2394662 1:CAS:528:DyaK3cXmtVyqsLk%3D (Pubitemid 20230941)
15. B Dawson GJ Henry C Goodman I Gillam JR Beilby S Ching V Fabian D Dasig P Morling BA Kakulus 2002 Effect of Vitamin C and E supplementation on biochemical and ultrastructural indices of muscle damage after a 21 km run Int J Sports Med 23 10 15 11774060 10.1055/s-2002-19273 1:CAS:528: DC%2BD38XhtVyrtr8%3D (Pubitemid 34033016)
16. JC Dekkers LJP van Doornen HCG Kemper 1996 The role of antioxidant vitamins and enzymes in the prevention of exercise-induced muscle damage Sports Med 21 213 238 8776010 10.2165/00007256-199621030-00005 1:STN:280: DyaK28znt1WrtQ%3D%3D (Pubitemid 26092730)
17. DB Dill DL Costill 1974 Calculation of percentage changes in volumes of blood, plasma and red cells in rehydration J Appl Physiol 37 247 248 4850854 1:STN:280:DyaE2c3pvV2ntw%3D%3D
18. CP Fischer NJ Hiscock M Penkowa S Basu B Vessby A Kallner LB Sjoberg BK Pedersen 2004 Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle J Physiol (Lond) 558 633 645 10.1113/jphysiol.2004.066779 1:CAS:528:DC%2BD2cXmtlKitbk%3D (Pubitemid 39117607)
19. J Friden RL Lieber 1992 Structural and mechanical basis of exercise-induced muscle injury Med Sci Sports Exerc 24 521 530 1569848 1:STN:280:DyaK383js1emsg%3D%3D
20. M Gleeson JD Robertson RJ Maughan 1987 Influence of exercise on ascorbic acid status in man Clin Sci (Lond) 73 501 505 1:CAS:528:DyaL2sXmtFKmsbs%3D (Pubitemid 18019697)
21. AH Goldfarb 1993 Antioxidants: role of supplementation to prevent exercise-induced oxidative stress Med Sci Sports Exerc 25 232 236 8450726 1:CAS:528:DyaK3sXitVCmsbY%3D (Pubitemid 23061985)
22. AH Goldfarb RJ Bloomer MJ McKenzie 2005 Combined antioxidant treatment effects on blood oxidative stress after eccentric exercise Med Sci Sports Exerc 37 234 239 15692318 10.1249/01.MSS.0000152887.87785.BE 1:CAS:528: DC%2BD2MXpsF2jtA%3D%3D (Pubitemid 40204629)
23. MC Gomez-Cabrera E Domenech M Romagnoli A Arduini C Borras FV Pallardo J Sastre J Vina 2008 Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance Am J Clin Nutr 87 142 149 18175748 1:CAS:528:DC%2BD1cXmt1amsw%3D%3D
24. B Halliwell S Chirico 1993 Lipid peroxidation: its mechanism, measurement, and significance Am J Clin Nutr 57 715S 724S 8475889 1:CAS:528:DyaK3sXltFCnsL0%3D
25. JN Hathcock A Azzi J Blumberg T Bray A Dickinson B Frei I Jialal CS Johnston FJ Kelly K Kraemer L Packer S Parthasarathy H Sies MG Traber 2005 Vitamins E and C are safe across a broad range of intakes Am J Clin Nutr 81 736 745 15817846 1:CAS:528:DC%2BD2MXjsFelt78%3D (Pubitemid 41724978)
26. V Herbert 1994 The antioxidant supplement myth Am J Clin Nutr 60 157 158 8030591 1:CAS:528:DyaK2MXosFOitg%3D%3D
27. D Hess HE Keller B Oberlin R Bonfanti W Schuep 1991 Simultaneous determination of retinol, tocopherols, carotenes and lycopene in plasma by means of high-performance liquid chromatography on reversed phase Int J Vitam Nutr Res 61 232 238 1794952 1:CAS:528:DyaK3MXmt1Ontr8%3D
28. WG Hopkins SW Marshall AM Batterham J Hanin 2009 Progressive statistics for studies in sports medicine and exercise science Med Sci Sports Exerc 41 3 13 19092709
29. G Howatson KA van Someren 2008 The prevention and treatment of exercise-induced muscle damage Sports Med 38 483 503 18489195 10.2165/00007256-200838060-00004 (Pubitemid 351704854)
30. Howatson G, McHugh MP, Hill JA, Brouner J, Jewell AP, van Someren KA, Shave RE, Howatson SA (2009) Influence of tart cherry juice on indices of recovery following marathon running. Scand J Med Sci Sports. doi: 10.1111/j.1600-0838.2009.01005.x
31. P Jakeman S Maxwell 1993 Effect of antioxidant vitamin supplementation on muscle function after eccentric exercise Eur J Appl Physiol 67 426 430 10.1007/BF00376459 1:STN:280:DyaK2c7jtVyktw%3D%3D (Pubitemid 23343674)
32. MM Kanter LA Nolte JO Holloszy 1993 Effects of an antioxidant vitamin mixture on lipid peroxidation at rest and post exercise J Appl Physiol 74 965 969 8458821 1:CAS:528:DyaK3sXisFert70%3D (Pubitemid 23078202)
33. M Khassaf A McArdle C Esanu A Vasilaki F McArdle RD Griffiths DA Brodie MJ Jackson 2003 Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle J Physiol (Lond) 549 645 652 10.1113/jphysiol.2003.040303 1:CAS:528:DC%2BD3sXlslWnt78%3D (Pubitemid 36701774)
34. JP Kirwan RC Hickner KE Yarasheski WM kohrt BV Wiethop JO Holloszy 1992 Eccentric exercise induces transient insulin resistance in healthy individuals J Appl Physiol 72 2197 2202 1629073 10.1063/1.351611 1:CAS:528:DyaK38Xlt1Gjs7w%3D
35. J Komulainen TE Takala V Vihko 1995 Does increased serum creatine kinase activity reflect exercise-induced muscle damage in rats? Int J Sports Med 16 150 154 7649704 10.1055/s-2007-972983 1:CAS:528:DyaK2MXntValt74%3D
36. 2-isoprostanes as a reliable index of oxidative stress in vivo using gas chromatography-mass spectrometry (GC-MS) method Free Radic Biol Med 47 1101 1107 19647073 10.1016/j.freeradbiomed.2009.07.028 1:CAS:528:DC%2BD1MXhtFGqsbjN
37. G Machefer C Groussard S Vincent H Zouhal H Faure J Cillard Z Radak A Gratas-Delamarche 2007 Multivitamin-mineral supplementation prevents lipid peroxidation during "the Marathon des Sables" J Am Coll Nutr 26 111 120 17536122 1:CAS:528:DC%2BD2sXot1eiu70%3D (Pubitemid 46911254)
38. I Margaritis F Tessier F Verdera S Bermon P Marconnet 1999 Muscle enzyme release does not predict muscle function impairment after triathlon J Sports Med Phys Fitness 39 133 139 10399422 1:CAS:528:DyaK1MXktlCgtrs%3D (Pubitemid 29283711)
39. A Mastaloudis JD Morrow DW Hopkins S Devaraj MG Traber 2004 Antioxidant supplementation prevents exercise-induced lipid peroxidation, but not inflammation, in ultramarathon runners Free Radic Biol Med 36 1329 1341 15110397 10.1016/j.freeradbiomed.2004.02.069 1:CAS:528:DC%2BD2cXjsVelsb0%3D (Pubitemid 38526325)
40. A Mastaloudis MG Traber K Carstensen JJ Widrick 2006 Antioxidants did not prevent muscle damage in response to an ultramarathon run Med Sci Sports Exerc 38 72 80 16394956 10.1249/01.mss.0000188579.36272.f6 1:CAS:528: DC%2BD28Xht1agsQ%3D%3D (Pubitemid 43062959)
41. JN Matthews DG Altman MJ Campbell P Royston 1990 Analysis of serial measurements in medical research Br Med J 300 230 235 10.1136/bmj.300.6719.230 1:STN:280:DyaK3c7otFKqsg%3D%3D (Pubitemid 20045528)
42. M Meydani WJ Evans G Handelman L Biddle RA Fielding SN Meydani J Burrill MA Fiatarone JB Blumberg JG Cannon 1993 Protective effect of vitamin E on exercise-induced oxidative damage in young and older adults Am J Physiol 264 R992 R998 8498608 1:CAS:528:DyaK3sXkslWnt78%3D
43. JP Morton L Croft JD Bartlett DP Maclaren T Reilly L Evans A McArdle B Drust 2009 Reduced carbohydrate availability does not modulate training-induced heat shock protein adaptations but does upregulate oxidative enzyme activity in human skeletal muscle J Appl Physiol 106 1513 1521 19265068 10.1152/ japplphysiol.00003.2009 1:CAS:528:DC%2BD1MXlvFOgsL8%3D
44. AV Ng JC Agre P Hanson MS Harrington FJ Nagle 1994 Influence of muscle length and force on endurance and pressor responses to isometric exercise J Appl Physiol 76 2561 2569 7928884 1:STN:280:DyaK2M%2Fhtl2hsA%3D%3D (Pubitemid 24184779)
45. CW Nicholas FE Nuttall C Williams 2000 The Loughborough intermittent shuttle test: a field test that simulates the activity pattern of soccer J Sports Sci 18 97 104 10718565 10.1080/026404100365162 1:STN:280: DC%2BD3c7otFCqsQ%3D%3D (Pubitemid 30098662)
46. H Onishi R Yagi M Oyama K Akasaka K Ihashi Y Handa 2002 EMG-angle relationship of the hamstring muscles during maximum knee flexion J Electromyogr Kinesiol 12 399 406 12223173 10.1016/S1050-6411(02)00033-0 (Pubitemid 35291942)
47. L Packer 1992 Interactions among antioxidants in health and disease: vitamin E and its redox cycle Proc Soc Exp Biol Med 200 271 276 1579593 1:STN:280:DyaK383ltlGqsQ%3D%3D
48. JM Peake K Suzuki M Hordern G Wilson K Nosaka JS Coombes 2005 Plasma cytokine changes in relation to exercise intensity and muscle damage Eur J Appl Physiol 95 514 521 16151834 10.1007/s00421-005-0035-2 1:CAS:528: DC%2BD2MXht1Gisr3P (Pubitemid 41762557)
49. EM Peters R Anderson DC Nieman H Fickl V Jogessar 2001 Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides following ultramarathon running Int J Sports Med 22 537 543 11590482 10.1055/s-2001-17610 1:CAS:528:DC%2BD3MXotlGisLk%3D (Pubitemid 32980390)
50. EW Petersen K Ostrowski T Ibfelt M Richelle E Offord J Halkjaer-Kristensen BK Pedersen 2001 Effect of vitamin supplementation on cytokine response and on muscle damage after strenuous exercise Am J Physiol 280 C1570 C1575 1:CAS:528:DC%2BD3MXksFKnu7c%3D
51. SK Powers AJ Smuder AN Kavazis MB Hudson 2010 Experimental guidelines for studies designed to investigate the impact of antioxidant supplementation on exercise performance Int J Sport Nutr Exerc Met 20 2 14 1:CAS:528: DC%2BC3cXksVGksbk%3D
52. DB Pyne 1994 Exercise-induced muscle damage and inflammation: a review Aust J Sci Med Sport 26 49 58 8665277 1:STN:280:DyaK283ktFSlsA%3D%3D
53. L Rokitzki E Logemann AN Sagredos M Murphy W Wetzel-Roth J Keul 1994 Lipid peroxidation and antioxidative vitamins under extreme endurance stress Acta Physiol Scand 151 149 158 7942049 10.1111/j.1748-1716.1994.tb09732.x 1:CAS:528:DyaK2cXlslKjs7Y%3D
54. H Schroder E Navarro A Tramullas J Mora D Galiano 2000 Nutrition antioxidant status and oxidative stress in professional basketball players: effects of a three compound antioxidative supplement Int J Sports Med 21 146 150 10727077 10.1055/s-2000-8870 1:CAS:528:DC%2BD3cXit12gt7g%3D (Pubitemid 30128561)
55. LL Smith 1991 Acute inflammation: the underlying mechanism in delayed onset muscle soreness? Med Sci Sports Exerc 23 542 551 2072832 1:STN:280:DyaK3MzgsVaktQ%3D%3D
56. K Suzuki J Peake K Nosaka M Okutsu CR Abbiss R Surriano D Bishop MJ Quod H Lee DT Martin PB Laursen 2006 Changes in markers of muscle damage, inflammation and HSP70 after an Ironman Triathlon race Eur J Appl Physiol 98 525 534 17031693 10.1007/s00421-006-0296-4 1:CAS:528:DC%2BD28Xht1WhsbnF (Pubitemid 44767092)
57. VH Teixeira HF Valente SI Casal AF Marques PA Moreira 2009 Antioxidants do not prevent postexercise peroxidation and may delay muscle recovery Med Sci Sports Exerc 41 1752 1760 19657294 10.1249/MSS.0b013e31819fe8e3 1:CAS:528:DC%2BD1MXhtVSitrnN
58. D Thompson CW Nicholas C Williams 1999 Muscular soreness following prolonged intermittent high-intensity shuttle running J Sports Sci 17 387 395 10413266 10.1080/026404199365902 1:STN:280:DyaK1MzjvFKisw%3D%3D (Pubitemid 29250940)
59. D Thompson C Williams SJ McGregor CW Nicholas F McArdle MJ Jackson JR Powell 2001 Prolonged vitamin C supplementation and recovery from demanding exercise Int J Sport Nutr Exerc Met 11 466 481 1:CAS:528:DC%2BD38Xns1Ortg%3D%3D
60. D Thompson DM Bailey J Hill T Hurst JR Powell C Williams 2004 Prolonged vitamin C supplementation and recovery from eccentric exercise Eur J Appl Physiol 92 133 138 15024666 10.1007/s00421-004-1064-y 1:CAS:528: DC%2BD2cXksVentr4%3D (Pubitemid 38885871)
61. JA Warren RR Jenkins L Packer EH Witt RB Armstrong 1992 Elevated muscle vitamin E does not attenuate eccentric exercise-induced muscle injury J Appl Physiol 72 2168 2175 1629069 1:CAS:528:DyaK38XlvV2ntLg%3D
62. C Yfanti T Akerstrom S Nielsen AR Nielsen R Mounier OH Mortensen J Lykkesfeldt AJ Rose CP Fischer BK Pedersen 2010 Antioxidant supplementation does not alter endurance training adaptation Med Sci Sports Exerc 42 1388 1395 20019626 1:CAS:528:DC%2BC3cXns1ylu70%3D